# numbuz:n Pantothenic B5 Active Soothing Serum for oily acne-prone skin

**Lovi Fit: Superior fit for oily acne-prone skin.**
Oily Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [numbuz:n](https://lovi.care/skincare/de/brands/numbuz-n)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for oily acne-prone skin.

## Why this fit

- Excellent suitability for your oily skin and acne concerns is provided by Panthenol Vitamin B5 and Centella Asiatica Extract, which soothe inflammation and help regulate oil production. Hyaluronic acid and glycerin further enhance barrier resilience and hydration, ensuring your skin remains comfortable and balanced. The formula is exceptionally safe for your skin, with no reported irritation risks due to the absence of harsh ingredients and the inclusion of calming agents like Panthenol Vitamin B5 and Centella Asiatica Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin): Superior (this page)

## Key ingredients

Pantothenic Acid Vitamin B5, Hyaluronic Acid, Centella Asiatica Extract, Allantoin, Niacinamide

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## What reviewers say

This serum is widely praised by users with oily, acne-prone, and dehydrated skin for its ability to deeply hydrate without clogging pores or leaving a greasy residue. While many report significant improvements in redness and oil control, results vary for those with dry skin or specific sensitivities, with some users finding it insufficiently moisturizing on its own.

- Liked: Lightweight & fast (mostly mentioned)
- Liked: Hydrating for oily (often mentioned)
- Liked: Soothing redness (often mentioned)
- Liked: Oil control (sometimes noted)
- Disliked: Not enough moisture (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Price per volume (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes numbuz:n Pantothenic B5 Serum one of the best fits for oily acne-prone skin?

This serum is an excellent fit for your oily acne-prone skin because Panthenol Vitamin B5 and Centella Asiatica Extract soothe redness and help balance oil. Hyaluronic acid and glycerin also keep your skin comfortably hydrated without feeling heavy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Panthenol Vitamin B5 and Centella Asiatica Extract make this serum a great fit because they soothe inflammation and help regulate oil production. Hyaluronic acid and glycerin also keep your oily skin comfortable and balanced by boosting hydration and strengthening your skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Pantothenic Acid do for oily acne-prone skin?

Pantothenic acid helps regulate sebum and reduce blemishes for oily acne-prone skin while improving hydration and calming redness. It is unlikely to cause irritation and is well tolerated by sensitive skin types.
Sources: [Dermatology and Therapy, 2014](https://pubmed.ncbi.nlm.nih.gov/24831048/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing, for simplicity and extra safety around sun exposure. Some serums can also be used in the morning or twice a day.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to keep your skin calm and comfortable. Panthenol Vitamin B5 and Centella Asiatica Extract help soothe potential irritation, while hyaluronic acid and glycerin support your skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

You can use this treatment in your evening routine, applying it after cleansing and toning and before moisturizing. Daily application is unlikely to cause irritation and helps keep your skin calm, comfortable, and balanced.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause breakouts on oily acne-prone skin because it contains calming agents like Panthenol Vitamin B5 and Centella Asiatica Extract that soothe inflammation without heavy, pore-blocking oils. The formula also has an excellent safety profile with no harsh ingredients that typically trigger irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this serum around the eyes or on my body?

You can safely use this moisturizing treatment on your body and the thin skin around your eyes because its gentle ingredients like Panthenol Vitamin B5 and Centella Asiatica Extract soothe irritation and hydrate without harsh additives. Studies show that panthenol and hydrating fluids improve skin comfort and barrier strength across various body regions without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/de/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — €15.99 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/de/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-acne-prone-skin) — High fit — €17.99 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/de/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/oily-acne-prone-skin) — High fit — €29.98 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/de/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon

## Where to buy

- Amazon.de: €18.50 (https://www.amazon.de/dp/B0D176VZP2?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €22.99 (https://www.lookfantastic.de/p/numbuzin-no.1-pantothenic-b5-active-soothing-serum-50ml/17027861/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Water, Panthenol Vitamin B5, Glycerin, Butylene Glycol, Hyaluronic Acid, Allantoin, Centella Asiatica Extract, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Beta-Glucan, Sodium Pca, Tocopherol Vitamin E, Caprylyl Glycol, Ethylhexylglycerin, 1,2-Hexanediol, Carbomer, Arginine, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin (this page)
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- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin