# Neutrogena Hydro Boost+ Niacinamide Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Neutrogena](https://lovi.care/skincare/de/brands/neutrogena)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your oily skin, this serum effectively addresses acne, blemishes, and breakouts by utilizing niacinamide and acetyl glucosamine to regulate oil production and reduce inflammation.
- The inclusion of glycerin provides excellent moisturizing benefits, smoothing skin texture and enhancing overall hydration without compromising your skin type.
- This formula is safe for your skin, as it contains no harsh ingredients and poses no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Niacinamide, Sodium Hyaluronate, Glycerin, Acetyl Glucosamine, Dimethicone

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## What reviewers say

This fragrance-free serum is widely praised for its lightweight, fast-absorbing texture that delivers immediate hydration without greasiness, making it suitable for both oily and dry skin types. Users frequently report improvements in skin texture and brightness, though results regarding dark spots and pore size can vary, with a small minority experiencing breakouts. Based on a very large amount of data, this should be definitely taken into account.

- Liked: Lightweight & fast (mostly mentioned)
- Liked: Effective hydration (often mentioned)
- Liked: Gentle & fragrance-free (often mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Evens skin tone (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Neutrogena Hydro Boost+ Niacinamide Serum a great fit for oily acne-prone skin?

Neutrogena Hydro Boost+ Niacinamide Serum is a great fit because it uses niacinamide and acetyl glucosamine to calm breakouts and control extra oil without feeling heavy. Glycerin and sodium hyaluronate add lightweight hydration to keep your skin smooth and comfortable. The formula is very safe and unlikely to cause any irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide and acetyl glucosamine make this serum a great fit for your oily acne-prone skin by helping to control oil and calm redness. Glycerin and sodium hyaluronate also add light hydration to keep your skin smooth without feeling greasy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and safe around sun exposure. It helps clear breakouts and hydrates your skin without feeling heavy.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use it with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to help keep your skin calm and hydrated. Using a barrier-supporting product alongside retinol may help reduce irritation and keep your skin smooth.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this serum?

You can use this serum in your evening routine for simplicity and extra safety around sun exposure. This formula is safe for your skin, as it contains no harsh ingredients and poses no risk of irritation.

### Can it clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is a great fit and is unlikely to cause breakouts or clog pores for your oily acne-prone skin. It contains ingredients that help control oil and reduce redness without irritation, though a few reviewers have reported minor breakouts.

### Can I use it around the eyes or on my body?

You can safely use this serum around the eyes and on your body because its gentle formula poses no risk of irritation. It provides great hydration and helps smooth skin texture without feeling heavy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/de/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/oily-acne-prone-skin) — Superior fit — €37.64 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/de/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — €15.99 at Amazon
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/de/p/isntree/green-tea-fresh-serum/for/oily-acne-prone-skin) — High fit — €12.56 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/de/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon

## Where to buy

- Amazon.de: €10.49 (https://www.amazon.de/dp/B0DYVL6M3S?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €12.50 (https://www.notino.de/neutrogena/hydro-boost-hydratisierendes-serum-mit-niacinamid/p-16298757/)
Prices checked 10 Oct – 5 Nov 2026.

## Ingredients

Water, Niacinamide, Glycerin, Acetyl Glucosamine, Pentylene Glycol, Dimethicone, Phenoxyethanol, Carbomer, Disodium Edta, Sodium Hyaluronate, Sodium Hydroxide, Ethylhexylglycerin, Dimethicone Vinyl Dimethicone Crosspolymer, Amodimethicone
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-acne-prone-skin