# NATURIUM Azelaic Topical Acid 10% for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [NATURIUM](https://lovi.care/skincare/de/brands/naturium)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this formula features potassium azeloyl diglycinate and niacinamide to help regulate sebum and repair your skin barrier, addressing your concerns about wrinkles and fine lines by promoting collagen production and antioxidant protection.
- Ethyl ascorbic acid further enhances skin tone evening and provides antioxidant benefits, complementing the primary ingredients.
- The product is safe for your skin, with no reported risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Niacinamide, Ethyl Ascorbic Acid Ascorbic Acid, Potassium Azeloyl Diglycinate, Sodium Hyaluronate

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical delivery of L-ascorbic acid derivatives via emulgels increased skin hydration and skin whitening potential without significantly altering TEWL or pH over a 30-day in vivo study. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36986679/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Most users report improved skin texture and a brighter complexion without experiencing irritation. A smaller number of users noted initial breakouts or found the scent to be unpleasant.

- Liked: Improves texture (mostly mentioned)
- Liked: Clears acne (often mentioned)
- Liked: Gentle and non-irritating (often mentioned)
- Liked: Reduces redness (often mentioned)
- Liked: Elegant texture (sometimes noted)
- Disliked: Unpleasant smell (sometimes noted)
- Disliked: Drying or sticky (rarely noted)
- Disliked: Initial breakouts (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Naturium Azelaic Topical Acid 10% a great fit for mature skin?

This formula is a great fit for mature skin because it uses niacinamide and potassium azeloyl diglycinate to help smooth wrinkles and fine lines by supporting collagen production and repairing your skin barrier. It also includes vitamin C derivatives to help even out your skin tone and provide antioxidant protection. The product is very safe for your skin, with no reported risks of irritation.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Which ingredients make this cream a good fit for mature skin?

This cream is a great fit for mature skin because it contains potassium azeloyl diglycinate and niacinamide to help repair your skin barrier and reduce wrinkles. Ethyl ascorbic acid and sodium hyaluronate further help smooth your skin and protect it against aging.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/), [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### What does Azelaic Acid do for mature skin?

Azelaic acid helps mature skin by targeting dark spots and uneven tone, while supporting smoother texture and a more youthful look. It provides antioxidant benefits that may reduce signs of aging and protect skin from environmental stress.
Sources: [Frontiers in Medicine, 2026](https://pubmed.ncbi.nlm.nih.gov/42023095/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/36056802/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this cream go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Treatments are placed in the evening for simplicity and extra safety around sun exposure.

### Can I use this cream with retinol, and in what order?

You can use this treatment alongside retinol, but to keep your skin calm, apply retinol on alternate nights or use it in your morning routine while saving this product for the evening. This helps prevent irritation while still giving you the smoothing and barrier-repairing benefits of both ingredients.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/), [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### How often should I use this cream?

This treatment is a great fit to use in your evening routine once a week to start, and you can carefully use it more often if your skin tolerates it well and shows good results. It is unlikely to cause irritation because it leaves out harsh or prohibited ingredients.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream has a low likelihood of causing initial breakouts for mature skin and is safe without harsh ingredients. It helps smooth lines while supporting your skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/), [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/de/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/de/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €169.99 at Amazon
- [La Prairie Skin Caviar Liquid Lift](https://lovi.care/skincare/de/p/la-prairie/skin-caviar-liquid-lift/for/mature-skin) — High fit — €730.48 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/de/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €14.00 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €51.50 at Amazon

## Where to buy

No store in Germany has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Potassium Azeloyl Diglycinate, Polyacrylate Crosspolymer-6, Niacinamide, Ethyl Ascorbic Acid, Caprylyl Glycol, Coffea Arabica Seed Extract Coffee Seed Extract, Sodium Hyaluronate, Phenylpropanol, Phenoxyethanol, Citric Acid, Potassium Chloride, Glycerin, Chlorphenesin, Tocopherol, Potassium Sorbate, Sodium Benzoate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/naturium/azelaic-topical-acid-10/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/mature-skin (this page)
- France: https://lovi.care/skincare/fr/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/naturium/azelaic-topical-acid-10/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/naturium/azelaic-topical-acid-10/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/naturium/azelaic-topical-acid-10/for/mature-skin