# MISSHA Super Aqua Ultra Hyalron Ampoule for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: Superior · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [MISSHA](https://lovi.care/skincare/de/brands/missha)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for mature skin.

## Why this fit

- Excellent suitability for your normal skin is provided by multiple forms of hyaluronic acid and glycerin, which offer superb humectant action and barrier support.
- This formula delivers excellent moisturizing treatment due to the presence of multiple forms of hyaluronic acid, such as sodium hyaluronate and hydrolyzed hyaluronic acid, in concentrations that provide deep hydration.
- The product is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

10x Hyaluronic Acid, Niacinamide, Avena Sativa Kernel Extract Oat Kernel Extract, Cynara Scolymus Leaf Extract, Beta-Glucan

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- A multiple W/O/W emulsion containing Rosmarinus officinalis L., Avena sativa L., and Linum usitatissimum L. extracts showed no irritant, phototoxic, inflammatory, or allergenic potential in human skin models and patch tests, establishing its safety as a cosmetic base. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34065623/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts. ([Clinical, Cosmetic and Investigational Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30519069/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))
- Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/))
- An artichoke extract cosmetic formulation enhanced skin roughness by 19.74% and elasticity by 11.45% in human subjects compared to a placebo cream, alongside exhibiting antioxidant, anti-inflammatory, and anti-aging cellular effects. ([Molecules, 2018](https://pubmed.ncbi.nlm.nih.gov/30360471/))
- Luteolin inhibited the mRNA expression of antimicrobial peptides and increased cornified envelope proteins in TNF-alpha/IL-17A/IFN-gamma-stimulated HaCaT cells by regulating the TRAF6/IkappaB/NF-kappaB signaling pathway. ([Food Science and Biotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40655288/))
- Antioxidants and luteolin topically applied decrease UV-B induced apoptosis and downregulate pro-inflammatory cytokines in kindler syndrome keratinocyte cultures. ([Human Molecular Genetics, 2016](https://pubmed.ncbi.nlm.nih.gov/27798104/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))

## What reviewers say

Users consistently praise this ampoule for its deep, non-sticky hydration and lightweight texture that absorbs quickly, making it highly suitable for sensitive, dehydrated, and dry skin types. While the majority report a "plumping" effect and a gentle experience, a small minority mention mild tingling or frustration with the dropper packaging when the product runs low.

- Liked: Deep hydration (mostly mentioned)
- Liked: Lightweight texture (mostly mentioned)
- Liked: Gentle formula (often mentioned)
- Liked: Generous size (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Mild irritation (rarely noted)
- Disliked: Price concerns (rarely noted)
- Disliked: Scent concerns (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes MISSHA Super Aqua Ultra Hyalron Ampoule a great fit for mature skin?

MISSHA Super Aqua Ultra Hyalron Ampoule is a great fit for mature skin because its multiple forms of hyaluronic acid and glycerin provide deep hydration and barrier support. It helps smooth dry areas and keeps skin looking plump and soft.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit because multiple forms of hyaluronic acid, glycerin, and niacinamide help deliver deep hydration, support the skin barrier, and keep mature skin feeling soft and smooth without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by significantly improving skin hydration, elasticity, and reducing the depth of wrinkles. Regular use of these formulations makes dry skin feel much softer and smoother while helping to diminish the appearance of fine lines over time.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. Putting serums and ampoules with active ingredients in the evening helps keep your routine simple and avoids extra safety concerns around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to give your skin deep hydration, followed by retinol once it absorbs. Using a hydrating product with barrier support helps reduce dryness and makes it easier for mature skin to tolerate retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

This serum fits into your evening routine as a treatment step, used once a day for simplicity and safety around sun exposure. Some serums can also be used in the morning or twice a day if your skin tolerates them well.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts for mature skin, as it has a very low risk of irritation and features a lightweight, hydrating formula. It uses multiple types of hyaluronic acid and glycerin to deeply quench dry skin without heavy, pore-clogging ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

Yes, you can safely use this moisturizing treatment on your body and around your eyes. Multiple forms of hyaluronic acid and glycerin deeply hydrate these areas while supporting the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene and linalool).

## Alternatives for mature skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/de/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/mature-skin) — Average fit — €17.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/de/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/mature-skin) — Average fit — €15.99 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/de/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/mature-skin) — Average fit — €29.98 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/de/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €14.00 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/de/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — €18.00 at Amazon

## Where to buy

- Amazon.de: €22.75 (https://www.amazon.de/dp/B0BNB38ZLT?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €22.50 (https://www.notino.de/missha/super-aqua-10x-ultra-hyalron-ampoule-intensives-feuchtigkeitsspendendes-gesichtsserum-mit-beruhigender-wirkung/p-16400748/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Water, Methylpropanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Niacinamide, Polyglycerin-3, Octyldodeceth-16, Ammonium Acryloyldimethyltaurate Vp Copolymer, Xanthan Gum, Ethylhexylglycerin, Pentylene Glycol, Adenosine, Methyl Diisopropyl Propionamide, Carbomer, Disodium Edta, Tromethamine, Cynara Scolymus Leaf Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Sodium Hyaluronate, Polyquaternium-51, Camellia Sinensis Leaf Water, Hydrogenated Lecithin, Beta-Glucan, Citrus Aurantium Dulcis Peel Oil, Bergamot Oil Fruit, Lavandula Angustifolia Oil Lavender Oil, Anthemis Nobilis Oil Flower, Tocopherol, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Propanediol, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Sodium Hyaluronate Crosspolymer, Magnesium Chloride, Potassium Hyaluronate, Glycine Soja Seed Extract Soybean Seed Extract, Tetrahydropiperine, Phloretin, Arginine, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin (this page)
- France: https://lovi.care/skincare/fr/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin