MISSHA Super Aqua Cell Renew Snail Hydro-Gel Face Mask for acne-prone skin

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Questions and answers

What the research says

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• Facial masks containing low-temperature extracted Portulaca oleracea protect sensitive skin from photothermal stimulation and improve skin barrier function during photorejuvenation.

  Cutaneous and Ocular Toxicology, 2025

• Portulaca oleracea extract ameliorated skin barrier damage and inflammation induced by combined exposure to glycolic acid and UVB in HaCaT cells.

  Cutaneous and Ocular Toxicology, 2022

• A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks.

  Journal of Cosmetic Dermatology, 2022

• HelixComplex snail mucus protected human keratinocytes and reconstructed human epidermis models from ozone-induced oxidative damage and pro-inflammatory response following exposure to 0.5 ppm ozone for 2 hours.

  PloS One, 2020

• Topical treatment with Snail Secretion Filtrate significantly improves the speed and percentage of wound area closure, enhances proliferation and tissue remodeling, and reduces inflammation in a full-thickness excisional wound model in mice compared to untreated controls.

  Veterinary Sciences, 2021

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical purslane at 5% and 10% concentrations achieved alleviation of symptoms and lesion remission comparable to topical 0.1% triamcinolone acetonide in 34 subjects with oral lichen planus over 90 days.

  BMC Oral Health, 2023

• Topical application of a crude extract of Portulaca oleracea accelerates wound healing by decreasing wound surface area and increasing tensile strength in Mus musculus JVI-1, with the greatest contraction achieved at a single dose of 50mg compared to other dosages.

  Journal of Ethnopharmacology, 2003

• A polysaccharide fraction (VPOP3) from Portulaca oleracea L. reduced reactive oxygen species and lipid peroxidation, inhibited UVB-induced apoptosis, and downregulated melanogenic signaling pathway proteins in cells and zebrafish.

  Phytomedicine, 2023

• Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream.

  International Journal of Molecular Medicine, 2016

• Topical chamomile oil combined with a night splint significantly improved the symptomatic and functional status of patients with severe carpal tunnel syndrome compared to placebo, while electrodiagnostic parameters showed no significant changes.

  Complementary Therapies in Clinical Practice, 2015

• German chamomile solution applied twice a day healed peristomal skin lesions significantly faster than once-a-day 1% hydrocortisone ointment in colostomy patients, with a mean healing time of 8.89 days versus 14.53 days.

  Ostomy/wound Management, 2011

Ingredients

Water, Glycerin, Snail Secretion Filtrate, 1,2-Hexanediol, Ceratonia Siliqua Gum, Portulaca Oleracea Extract, Centella Asiatica Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Sodium Hyaluronate, Potassium Hydroxide, Chondrus Crispus Extract, Phenoxyethanol, Peg-60 Hydrogenated Castor Oil, Hydrolyzed Collagen, Parfum, Dipotassium Glycyrrhizate, Methylparaben, Scutellaria Baicalensis Root Extract, Disodium Edta, Propylparaben, Carbomer, Camellia Sinensis Leaf Extract, Artemisia Princeps Leaf Extract, Houttuynia Cordata Extract, Caprylyl Glycol, Citrus Junos Fruit Extract, Lactobacillus Ferment, Ricinus Communis Seed Oil Castor Seed Oil

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.