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MEDIHEAL AGE-R for dry skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

MEDIHEAL AGE-R

Average

  • HighDry Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for dry skin; other serums fit it better.

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate skin firming for your dry skin due to collagen and peptides, which also provide emollient action and support barrier repair.
  • While the ingredients offer general skin conditioning, they are not specifically targeted to address dryness or flakiness.
  • The product is safe for your dry skin as it contains no prohibited or harsh ingredients, minimizing irritation risks.

How to apply

  • Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
  • Place the serum after cleansing and toner, but right before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
  • Apply the serum on slightly damp skin to help lock in extra moisture.
  • Avoid the eye area and do a patch test before your first use.

People Say

★4.4Overall rating based on 12.5k+ reviews

Based on a very large amount of data, users frequently achieve a 'glass skin' appearance and improved facial contouring, with many reporting enhanced product absorption and a more radiant complexion. While effective for dullness and mild sagging, results are highly dependent on consistent daily use, which some users find difficult to maintain. The device is also noted for improving skin texture and reducing pore visibility.

Highlights

  • Enhanced absorption Mostly Mentioned
    • “products absorb instantly”
    • “skincare feels supercharged”
    • “no sticky residue left”
    • “serums work better”
  • Glass skin glow Often Mentioned
    • “skin looks dewy”
    • “immediate glass skin”
    • “glow lasts all day”
    • “makeup sits better”
  • Time-consuming routine Often Mentioned
    • “hard to stick to”
    • “adds 10 mins to routine”
    • “gave up after a month”
    • “too much effort daily”
  • Improved texture Sometimes Noted
    • “bumps smoothed out”
    • “pores look smaller”
    • “texture is softer”
    • “makeup applies smoother”
  • Visible lifting Sometimes Noted
    • “jawline looks snatched”
    • “face feels tighter”
    • “reduced morning puffiness”
    • “cheekbones pop more”
  • High price point Sometimes Noted
    • “very pricey investment”
    • “gel is expensive”
    • “not worth the full price”
    • “wait for a sale”
  • Unpleasant sensation Sometimes Noted
    • “zaps hurt sensitive areas”
    • “teeth feel weird”
    • “muscle twitching is creepy”
    • “prickly sensation”
  • Potential irritation Rarely Noted
    • “caused small bumps”
    • “redness after use”
    • “broke me out”
    • “too harsh for sensitive skin”

Sources: lovi.care, medicube.us, amazon.com, youtube.com, reddit.com, cosmopolitan.com, and more

Questions and answers

How well does Mediheal AGE-R work for dry skin?

Mediheal AGE-R works reasonably well for dry skin, offering moderate firming and general conditioning with collagen and peptides, though it lacks ingredients specifically targeted at dryness and flakiness. A treatment for dry skin needs richly hydrating and soothing ingredients like propolis, ceramides, niacinamide, or bifida fermentation that specifically target hydration and skin barrier support.

Dermatology Practical & Conceptual, 2022Current Issues in Molecular Biology, 2024

Which ingredients make this cream a good fit for dry skin?

Collagen and peptides make this cream a fit for your dry skin because they help firm the skin and support barrier repair, though this skin needs ingredients that specifically target dryness and flakiness like propolis, niacinamide, ceramides, or vitamin C.

Dermatology Practical & Conceptual, 2022Current Issues in Molecular Biology, 2024

What does Glutathione do for dry skin?

Glutathione helps dry skin by improving moisture levels and smoothness while keeping the skin barrier strong against daily stress. Topical application of glutathione may also reduce water loss through the skin, helping your face feel softer and more hydrated.

Clinical, Cosmetic and Investigational Dermatology, 2014The Journal of Clinical and Aesthetic Dermatology, 2025

What does Collagen do for dry skin?

Collagen helps dry skin by boosting hydration, improving moisture levels, and supporting the skin barrier. This type of product may reduce water loss and keep skin feeling soft and smooth over time.

Current Issues in Molecular Biology, 2024International Journal of Molecular Sciences, 2021

Where does it go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though products of this type for dry skin work best when they also provide deep moisture and target flakiness using ingredients like hyaluronic acid or ceramides.

Can I use this cream with retinol, and in what order?

You can use this treatment with retinol, applying retinol first and following with this product to keep your skin safe. This treatment offers moderate firming with collagen and peptides, but to properly care for dry skin it needs richer moisturizing ingredients that directly target dryness and flakiness.

How often should I use it?

Use this treatment in your evening routine, applying it after cleansing and before moisturizing. While it helps firm and condition your dry skin, a product for this skin needs rich hydrating and moisturizing ingredients to properly target dryness and flakiness.

Dermatology Practical & Conceptual, 2022Current Issues in Molecular Biology, 2024

Can it clog pores, cause breakouts or purging for dry skin?

It is unlikely to clog pores or cause breakouts for dry skin since it has a safe formula with a low risk of irritation. However, because it is not specifically targeted to address dryness, a product for dry skin of this type needs rich moisturizing ingredients like ceramides or hyaluronic acid to properly comfort dry areas.

What the research says

  • Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen.

    Dermatology Practical & Conceptual, 2022

  • The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage.

    Current Issues in Molecular Biology, 2024

  • Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.

    Advanced Science, 2025

  • Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls.

    Journal of the European Academy of Dermatology and Venereology, 2024

  • Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2014

  • Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity.

    The Journal of Clinical and Aesthetic Dermatology, 2025

  • Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.

    Journal of Cosmetic Dermatology, 2022

  • Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.

    International Journal of Molecular Sciences, 2022

  • Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.

    Marine Drugs, 2023

Why other serums fit dry skin better

Ingredients

Glutathione, Collagen, Peptides

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

Scan your face, then any product.

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How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play