# Medicube Zero Pore One Day Serum for dry skin

**Lovi Fit: Low fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Medicube](https://lovi.care/skincare/de/brands/medicube)
Category: [Exfoliants](https://lovi.care/skincare/de/best/exfoliators)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for dry skin; the products alongside fit it better.

## Why this fit

- Offers moderate exfoliation for your dry skin due to gluconolactone and salicylic acid, which provide mild chemical exfoliation but may not be sufficient for significant hydration and could potentially exacerbate dryness.
- While glycerin and propanediol offer some humectant benefits, the formula lacks sufficient emollient and occlusive ingredients for optimal hydration for dry skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/dry-skin): Low (this page)
- [Combination skin](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Aha, Bha, Pha, Niacinamide, Salicylic Acid

## What the research says

- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## Why other products fit dry skin better

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))

## What reviewers say

Based on a very large amount of data, users with oily and combination skin frequently praise this serum for refining rough texture and minimizing enlarged pores, often describing a blurring effect that serves as a good makeup base. While the 'one day' claim is often viewed as marketing hyperbole, consistent use reportedly yields smoother skin and reduced sebum production, though the product's sticky finish is a polarizing feature.

- Liked: Smoothes texture (mostly mentioned)
- Disliked: Sticky finish (mostly mentioned)
- Liked: Tightens pores (often mentioned)
- Liked: Controls oil (sometimes noted)
- Liked: Hydrating formula (sometimes noted)
- Disliked: Causes irritation (sometimes noted)
- Disliked: Price vs quantity (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use this exfoliant as part of your PM routine once a week, increasing slowly to twice a week if your dry skin tolerates it well. Always remember to apply SPF every morning to protect your newly smoothed skin.
- Apply the exfoliant after cleansing and toning, but always before your rich moisturizer.
- Gently press 2-3 drops of the exfoliant into your skin and let it absorb for a minute. Avoid rubbing to prevent any irritation on flaky areas.
- Apply the product directly to dry clean skin to ensure the best possible tolerance for your dry type. This helps address flaky patches without causing extra stress.
- Avoid the sensitive eye area and do a quick patch test before your very first use. Do not mix this with other strong acids or retinoids on the same night.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### Why is Medicube Zero Pore One Day Serum a weak match for dry skin?

This serum is a weak match for dry skin because, while it offers mild exfoliation, it lacks enough heavy softening and sealing ingredients to keep dry skin comfortable and properly hydrated. An exfoliant treatment for dry skin needs deeply soothing and hydrating ingredients like ceramides, propolis, or peptides to nourish the skin barrier and prevent dryness.

### Which ingredients make this exfoliant a poor fit for dry skin?

This exfoliant is a weak match because gluconolactone and salicylic acid may not be enough for your dry skin and could potentially make dryness worse. This type of skin needs formulas rich in ceramides, vitamin C, peptides, or propolis for deep hydration and barrier support.

### What does Alpha Hydroxy Acid do for dry skin?

Alpha hydroxy acid helps smooth and hydrate dry skin by gently loosening dead surface skin cells and boosting natural moisture-locking lipids. Regular use makes dry skin feel softer and significantly improves rough patches.
Sources: [Cutis, 1998](https://pubmed.ncbi.nlm.nih.gov/9640557/), [Archives of Dermatological Research, 1996](https://pubmed.ncbi.nlm.nih.gov/8818186/)

### What does Bha do for dry skin?

BHA helps dry, flaking skin by gently clearing away dead buildup while improving moisture levels when paired with soothing hydrators like ceramides. Salicylic acid may help smooth rough patches, though dry skin types need to watch for irritation and support their skin barrier.
Sources: [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30681802/)

### Where does it go in a skincare routine for dry skin?

This exfoliant treatment goes in the evening routine once a week for dry skin, as treatments with active ingredients are used at night and exfoliating steps start slowly. This product is a weak match for dry skin because it lacks rich softening and sealing ingredients needed to keep dry skin comfortable and properly moisturized.

### Can I use this exfoliant with retinol, and in what order?

Using this exfoliant with retinol is not recommended for dry skin, as combining these strong treatments may easily trigger severe dryness, peeling, and irritation. When your skin is dry, an exfoliant of this type needs extra soothing ingredients, rich moisturizers, and barrier-protecting components to keep your skin soft and smooth.

### How often should I use it?

Start using this treatment once a week in the evening, as this lets you see how your skin reacts while avoiding extra dryness. A product for this skin needs rich moisturizers and skin-softening oils to keep it smooth and comfortable.

### Can this exfoliant clog pores, cause breakouts or purging for dry skin?

This exfoliant is unlikely to clog pores, but it may cause irritation and exacerbate dryness. An exfoliant for dry skin needs rich, moisturizing oils and butter ingredients to lock in hydration and keep the skin smooth.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €9.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/de/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/de/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €18.50 at Amazon

## Routine for dry skin

### AM

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €19.75 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/de/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — €12.59 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/de/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon
- SPF: [Australian Gold Botanical Sunscreen SPF 30](https://lovi.care/skincare/de/p/australian-gold/botanical-lotion-spf-30/for/dry-skin) — Superior fit — €21.04 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/de/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — €10.97 at Amazon
- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €19.75 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €9.99 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/de/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/de/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — €10.97 at Amazon
- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €19.75 at Amazon
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/de/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — €19.00 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €9.99 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/de/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

## Where to buy

- Amazon.de: €21.99 (https://www.amazon.de/dp/B09G267W27?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €15.50 (https://www.notino.de/medicube/zero-pore-one-day-serum-beruhigendes-und-hydratisierendes-serum-zur-verfeinerung-der-poren/p-16299735/)
Prices checked 16 Oct – 6 Nov 2026.

## Ingredients

Water, Gluconolactone, Methylpropanediol, Glycerin, Propanediol, Tromethamine, Polyglycerin-3, Niacinamide, 1,2-Hexanediol, Citric Acid, Dimethicone, Butylene Glycol, C12-14 Pareth-12, Hydroxyethylcellulose, Salicylic Acid, Ammonium Acryloyldimethyltaurate Vp Copolymer, Sodium Polyacryloyldimethyl Taurate, Lecithin, Allantoin, Lactic Acid, Glycolic Acid, Ethylhexylglycerin, Adenosine, Dextrin, Indigofera Tinctoria Extract, Sodium Hyaluronate, Sodium Citrate, Hemerocallis Fulva Flower Extract, Gardenia Fruit Extract, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Trisodium Phosphate, Of Myosotis Sylvatica Extract, Pentylene Glycol, Hydroxypropyltrimonium Hyaluronate, Sodium Acetylated Hyaluronate, Centella Asiatica Extract, Madecassoside, Lactobacillus Lysate Ferment, Dandelion Leaf Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/zero-pore-one-day-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-serum/for/dry-skin (this page)
- France: https://lovi.care/skincare/fr/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/zero-pore-one-day-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/zero-pore-one-day-serum/for/dry-skin