# medicube Exosome Cica Calming Toner for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [medicube](https://lovi.care/skincare/de/brands/medicube)
Category: [Toners](https://lovi.care/skincare/de/best/toners)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other toners fit it better.

## Why this fit

- Offers moderate hydration and soothing benefits for your dry and sensitive skin, as Centella Asiatica Extract and Glycerin provide supportive hydration and calming effects. Heart Leaf Extract further aids in reducing redness and irritation.
- The formula is generally safe for your dry and sensitive skin, as it lacks harsh ingredients and is free from irritants.
- While the glycerin offers humectant action, the product lacks sufficient emollient ingredients for optimal hydration for dry skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Exosome, Heart Leaf Extract

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Adjuvant application of human adipose tissue stem cell-derived exosomes gel following fractional CO2 laser significantly improved the reduction of acne scars (32.5% vs 19.9%, p < 0.01) and reduced erythema and downtime in 25 patients compared to the control gel. ([Acta Dermato-venereologica, 2020](https://pubmed.ncbi.nlm.nih.gov/33073298/))
- Topical mesenchymal stem cell-derived exosomes reduced Ocular Surface Disease Index scores, increased tear secretion, lowered fluorescein scores, prolonged tear-film break-up time, increased Epidermal Growth Factor and thrombospondin-1, and decreased interleukin-6 and Matrix metalloproteinase-9 in patients with Sjögren's syndrome-related dry eye compared to phosphate buffered saline control. ([BMC Ophthalmology, 2025](https://pubmed.ncbi.nlm.nih.gov/40394561/))
- Topical human platelet extract exosome serum improved skin health scores and reduced redness, wrinkles, and melanin production while enhancing luminosity and color evenness at 6 weeks. ([Aesthetic Surgery Journal, 2022](https://pubmed.ncbi.nlm.nih.gov/35689936/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))

## Why other toners fit dry sensitive skin better

- Topical 7% ectoine during serial 1064-nm Nd:YAG laser therapy produced a greater reduction in skin erythema, improved stratum corneum hydration, reduced transepidermal water loss, and decreased low-echogenic pixels in thirty participants compared to a vehicle control. ([Biomedicines, 2026](https://pubmed.ncbi.nlm.nih.gov/42792808/))
- Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream. ([International Journal of Molecular Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27279007/))

## What reviewers say

This toner is highly praised for its lightweight, watery texture that absorbs quickly without stickiness, making it suitable for oily and acne-prone skin. It is very effective at reducing redness and soothing irritation, with many users reporting improved skin balance. Some users noted concerns about the scent, price, and potential for fungal acne, though these were less common observations.

- Liked: Calms redness (mostly mentioned)
- Liked: Lightweight absorption (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Improves acne (sometimes noted)
- Disliked: Not fungal acne safe (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Scent preferences (rarely noted)
- Disliked: Unclear long-term benefits (rarely noted)

## How to apply

- You can use this soothing toner AM and PM every day. Always pair with SPF in the morning.
- Apply this soothing toner after your cleanser and before your moisturizer .
- Gently press 2-3 drops of the soothing toner into your skin and let it absorb. Avoid rubbing.
- Apply the soothing toner on slightly damp skin to help with absorption. This is great for dry skin.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does medicube Exosome Cica Calming Toner work for dry sensitive skin?

This toner works reasonably well for your dry sensitive skin, offering moderate hydration and calming benefits with Centella Asiatica Extract and glycerin. It is generally safe and lacks harsh irritants, but dry skin of this type needs additional softening ingredients to lock in optimal moisture.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this toner a good fit for dry sensitive skin?

Centella Asiatica Extract, glycerin, and heart leaf extract make this toner a good fit by offering supportive hydration and calming effects that help reduce redness and irritation in dry sensitive skin. However, because dry skin needs rich, softening ingredients to lock in moisture, a product of this type needs additional rich, softening ingredients for optimal hydration.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica Extract do for dry sensitive skin?

Centella asiatica extract helps calm dry sensitive skin by reducing irritation and improving moisture while protecting the skin barrier. Clinical studies show that regular use noticeably decreases redness and discomfort while keeping the skin soft and hydrated.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What do Exosomes do for dry sensitive skin?

Exosomes help calm dry sensitive skin by locking in moisture and repairing the outer skin barrier so it feels much smoother and less irritated. This type of care works best when it includes gentle, deeply soothing ingredients like ceramides and plant extracts to keep the skin soft and protected.
Sources: [Cells, 2020](https://pubmed.ncbi.nlm.nih.gov/32164386/), [Pharmaceutics, 2025](https://pubmed.ncbi.nlm.nih.gov/40430891/)

### Where does it go in a skincare routine for dry sensitive skin?

You can use this soothing toner in the morning after cleansing and before your moisturizing SPF, and again in the evening before your treatment and moisturizer. It helps calm your skin and provides moderate hydration, though dry skin generally needs richer creams with plenty of softening ingredients to lock in moisture.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this toner with retinol, and in what order?

You can use this toner with your retinol in the evening by applying the toner first to calm your skin and then following it with your treatment. While Centella Asiatica Extract and glycerin help provide supportive hydration and soothing benefits, this product lacks sufficient smoothing and softening ingredients that dry skin needs for optimal moisture alongside strong treatments.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

You can use this soothing toner twice a day in both your morning and evening routines. It helps calm dry and sensitive skin, though this skin type needs extra moisturizing ingredients to stay fully hydrated.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this toner clog pores, cause breakouts or purging for dry sensitive skin?

This toner is unlikely to clog pores or cause breakouts for dry sensitive skin, as it is generally safe and free from harsh ingredients and irritants.

## Alternatives for dry sensitive skin

- [La Roche-Posay Soothing Lotion Sensitive Skin Toner](https://lovi.care/skincare/de/p/la-roche-posay/soothing-lotion-sensitive-skin/for/dry-sensitive-skin) — Average fit — €20.95 at Amazon
- [COSRX Cica Toner](https://lovi.care/skincare/de/p/cosrx/cica-toner/for/dry-sensitive-skin) — High fit — €20.90 at Notino

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/de/p/torriden/dive-in-mild-sunscreen/for/dry-sensitive-skin) — Superior fit — €18.00 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/de/p/missha/ultra-hyalon-cleansing-cream/for/dry-sensitive-skin) — Superior fit — €10.97 at Amazon

## Where to buy

- Notino: €20.90 (https://www.notino.de/medicube/exosome-cica-toner-erfrischendes-gesichtstonikum-zur-beruhigung-der-haut/p-16359264/)
Prices checked 10 Oct 2026.

## Ingredients

Centella Asiatica Extract, Exosome, Heart Leaf Extract, Extract Tree, Glycerin, Butylene Glycol, Water
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin (this page)
- France: https://lovi.care/skincare/fr/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin