# Medicube EXOSOME CICA CALMING PAD for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Medicube](https://lovi.care/skincare/de/brands/medicube)
Category: [Toners](https://lovi.care/skincare/de/best/toners)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other toners fit it better.

## Why this fit

- Offers moderate soothing for your oily skin, as exosome cica and niacinamide help calm irritation and niacinamide offers some seboregulation.
- While these ingredients provide general calming benefits, they are not specialized for managing oily shine.
- The product is safe for your oily skin with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/oily-acne-prone-skin): Average

## Key ingredients

Exosome Cica, Tree, Niacinamide

## What the research says

- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Dermocosmetic loaded with plant extract significantly improved skin texture and surface parameters including roughness, scaliness, smoothness, and wrinkles compared to a base without extract in Asian male volunteers over three months. ([Pakistan Journal of Pharmaceutical Sciences, 2020](https://pubmed.ncbi.nlm.nih.gov/32276894/))
- A cosmetic cream containing Harungana madagascariensis plant extract induces similar anti-aging effects to a retinol-containing cream on 46 human subjects, improving wrinkles, ptosis, color homogeneity, smoothness, plumpness, firmness, and elasticity. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37155516/))
- An OTC topical formulation containing a plant extract complex improved skin extensibility and firmness significantly (P < 0.02) compared to placebo in 20 volunteers, with no adverse reactions. ([International Journal of Cosmetic Science, 2000](https://pubmed.ncbi.nlm.nih.gov/18503475/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## What reviewers say

Based on a very large amount of data, users with sensitive and acne-prone skin frequently praise these pads for their immediate cooling and redness-reducing effects, often noting significant relief from facial heat and irritation. While most find them highly hydrating and effective for smoothing skin texture, a minority of users felt they were less effective for active blemishes or found the pad material slightly rough.

- Liked: Rapid soothing cooling (mostly mentioned)
- Liked: Hydrating non-sticky (often mentioned)
- Liked: Generous essence (sometimes noted)
- Liked: Gentle exfoliation (sometimes noted)
- Liked: High adherence (sometimes noted)
- Disliked: High price point (rarely noted)
- Disliked: Ineffective on acne (rarely noted)
- Disliked: Pad texture rough (rarely noted)
- Disliked: Strong scent (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using your soothing toner 3 times a week and work up to daily use if your skin likes it.
- Apply your soothing toner after cleansing and before your moisturizer or SPF.
- Gently press 2-3 drops of the soothing toner into your skin with your hands. Let it absorb for a minute before moving on ⏱ to the next step.
- For the best results , apply your soothing toner to slightly damp skin to help it sink in better.
- Avoid the sensitive eye area and do a quick patch test before using the soothing toner for the very first time.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does medicube Exosome Cica Calming Pad work for oily skin?

This soothing toner offers moderate soothing for your oily skin, as exosome cica and niacinamide help calm irritation and niacinamide offers some seboregulation. While these ingredients provide general calming benefits, they are not specialized for managing oily shine, though the product is safe for your oily skin with no risks of irritation. A soothing toner for oily skin needs ingredients that help control excess oil and prevent breakouts while keeping the skin balanced and smooth.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Which ingredients make this toner a good fit for oily skin?

Exosome cica and niacinamide make this toner a moderate fit for oily skin because they help calm irritation and offer some oil control. However, this skin needs a soothing toner that controls excess oil and minimizes shine more specifically.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What do Exosomes do for oily skin?

Exosomes help balance oily skin by regulating sebum production and supporting cell activity. Because oily skin needs ingredients that control excess oil without causing irritation, this type of product should include soothing and balancing components.
Sources: [Biochimie, 2026](https://pubmed.ncbi.nlm.nih.gov/42833608/), [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37749255/)

### What does Tea Tree Oil do for oily skin?

Tea tree oil helps calm breakouts and keeps oily skin clear by reducing blemishes and redness. It works well against mild acne and is unlikely to irritate when used properly.
Sources: [Indian Journal of Dermatology, Venereology and Leprology, 2007](https://pubmed.ncbi.nlm.nih.gov/17314442/), [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/)

### Where does this toner go in a skincare routine for oily skin?

This soothing toner goes in your morning routine after cleansing and before your moisturizer and SPF, or in your evening routine after cleansing and before your treatment. Because it only offers moderate calming and lacks specialized oil control, oily skin needs products featuring stronger oil-balancing and shine-managing ingredients for a better fit.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Can I use this toner with retinol, and in what order?

You can use this toner with retinol by applying the toner first to calm your skin before your retinol treatment. This product is unlikely to cause irritation on oily skin, but an oily skin routine often needs specialized ingredients that control shine and balance oil production.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### How often should I use this toner?

You can use this soothing toner daily, as it is safe for oily skin and helps calm irritation without harsh risks. However, because it is not specialized for managing oily shine, oily skin also needs products with oil-controlling ingredients like salicylic acid or clay to keep excess oil in check.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Can this toner clog pores, cause breakouts or purging for oily skin?

This toner is unlikely to clog pores or cause breakouts for oily skin, as it has a safe profile with no harsh ingredients. However, it may not effectively manage oily shine or breakouts, as this skin type needs specialized ingredients for excess oil and blemishes.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

## Alternatives for oily skin

- [belif Problem Solution Toner](https://lovi.care/skincare/de/p/belif/problem-solution-toner/for/oily-skin) — Superior fit — €56.50 at Amazon
- [MEDIHEAL Tea Tree Biome Blemish Cica Pad](https://lovi.care/skincare/de/p/mediheal/tea-tree-biome-blemish-cica-pad/for/oily-skin) — High fit — €24.00 at Amazon
- [iUnik Tea Tree Relief Toner](https://lovi.care/skincare/de/p/iunik/tea-tree-relief-toner/for/oily-skin) — High fit — €19.59 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €11.75 at Amazon
- Moisturizer: [CeraVe CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/oily-skin) — Superior fit — €38.99 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/de/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — €32.80 at Amazon

## Where to buy

- Amazon.de: €35.00 (https://www.amazon.de/dp/B0DFG4MRC9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €26.50 (https://www.notino.de/medicube/exosome-cica-calming-pad-tonisierende-pads-mit-beruhigender-wirkung/p-16359263/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Exosome Cica, Tree, Niacinamide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/exosome-cica-calming-pad/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/oily-skin (this page)
- France: https://lovi.care/skincare/fr/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/exosome-cica-calming-pad/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/exosome-cica-calming-pad/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/exosome-cica-calming-pad/for/oily-skin