Le Mieux Bio Cell Rejuvenating Cream for oily skin
Sodium Hyaluronate
Squalane
Argan Oil
Acetyl Hexapeptide-8
Ceramide Np
Average
- AverageOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your oily skin, as Sodium Hyaluronate and Squalane provide essential hydration and emollient action without directly addressing concerns about oily shine.
- While the formula is generally supportive for oily skin, it lacks sufficient ingredients for strong oil control, and the inclusion of Shea Butter may not be ideal for managing excess sebum.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.
How to apply
- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
People Say
★4.9Overall rating based on 300+ reviewsThis moisturizer is widely celebrated for its rich, non-greasy formula that effectively targets dehydration, loss of firmness, and fine lines. It is particularly favored by users with dry or mature skin types who seek a product that leaves the complexion feeling soft, supple, and visibly rejuvenated.
Highlights
Deep hydration Mostly Mentioned
- “Leaves my skin feeling hydrated and dewy for hours.”
- “Provides immediate and lasting moisture.”
- “My skin feels soft, radiant, and hydrated.”
Radiant finish Often Mentioned
- “Leaves skin glowing.”
- “Gives me a glass glowing skin.”
- “Perfect for those seeking a radiant, youthful glow.”
Silky texture Often Mentioned
- “Melts into the skin quickly without greasy residue.”
- “Silky lotion/cream texture that feels amazing.”
- “Lightweight yet creamy, not too heavy.”
Improves lines Sometimes Noted
- “Helps improve the appearance of fine lines and wrinkles.”
- “Smooths the look of lines and wrinkles.”
- “Skin looks smoother and more youthful.”
Irritation risk Rarely Noted
- “There are some common irritants in this product.”
- “Ingredients might not have benefits for all skin.”
Price point Rarely Noted
- “If they're a little too expensive, I have other favorites.”
- “Not necessarily better than affordable options.”
Too rich Rarely Noted
- “It was too rich for even my dry skin.”
- “Might be too heavy for some skin types.”
- “Suggest it only for very dry, mature skin.”
Sources: lovi.care, skinbeautifulrx.com, skin-beauty.com, lemieuxpro.com, lemieuxskincare.com, artofskincare.com, and more
Questions and answers
How well does Bio Cell Rejuvenating Cream work for oily skin?
This cream offers moderate suitability for oily skin, providing hydration without directly addressing oily shine. It lacks strong oil control ingredients, and heavier components like shea butter may not be ideal for managing excess sebum. A product for oily skin needs lightweight textures, effective oil control ingredients, and a lack of heavy oils to prevent excess oiliness and breakouts.
Skin Pharmacology and Physiology, 2022International Journal of Dermatology, 2008
Which ingredients make this cream a good fit for oily skin?
Sodium hyaluronate and squalane make this cream a fit for oily skin by providing essential hydration without heavy oils, while ceramides support your skin barrier. Oily skin works best with products that control shine, maintain a lightweight texture, and avoid heavy butters.
International Journal of Dermatology, 2008Skin Pharmacology and Physiology, 2022
What does Hyaluronic Acid do for oily skin?
Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
What does Squalane do for oily skin?
Squalane helps keep oily skin soft and smooth without feeling heavy, though oxidized forms may sometimes trigger irritation. To work well for oily skin, this type of product needs lightweight, non-clogging ingredients that balance moisture without adding excess grease.
Where does this cream go in a skincare routine for oily skin?
This moisturizing treatment goes near the end of your evening routine, right before your moisturizer. It is generally safe for your skin, though it lacks strong oil control and contains shea butter, which may not be ideal for managing excess shine. Oily skin works best with lightweight hydrators and oil-controlling ingredients like niacinamide.
Can I use this cream with retinol, and in what order?
You can use this cream alongside retinol to help keep your skin comfortable and hydrated, applying the retinol first and following with the cream once it absorbs. Using a barrier-supporting moisturizer alongside active treatments is generally safe and helps reduce dryness without lowering the treatment's effectiveness.
How often should I use this cream?
You can use this moisturizing treatment twice daily as part of your morning and evening routine. It works for your oily skin by providing hydration, though oily skin types generally need formulas with strong oil control and lighter ingredients like niacinamide or salicylic acid instead of heavy butters.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for oily skin?
This cream is unlikely to cause irritation or breakouts on oily skin, though its richer texture may not actively help control excess shine. Oily skin often needs lightweight, oil-balancing ingredients and mattifying components to keep pores clear.
Can I use this cream around the eyes or on my body?
This cream is generally safe for the delicate skin around the eyes and on the body, though oily skin may benefit more from lightweight hydration and ingredients that control excess shine without heavy butters.
Surgical and Radiologic Anatomy, 2002International Journal of Dermatology, 2008
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022Peroxidated squalene induces an early activation of NF-kappaB, an increase in PPARalpha levels, and an upregulation of IL-6 production in HaCaT keratinocytes, which is subsequently counteracted by PPARalpha activation.
The Journal of Investigative Dermatology, 2006Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.
International Journal of Dermatology, 2008A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.
Lasers in Medical Science, 2025A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.
Skin Pharmacology and Physiology, 2022Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Topical application of an argan oil NLC-based hydrogel formulation increased skin hydration in healthy volunteers over a one-month period through a synergistic effect of NLC occlusion and argan oil hydration.
International Journal of Nanomedicine, 2014Incorporating allantoin into argan oil enriched liposomes improved its accumulation in the dermis (~8.7μg/cm(2)) and permeation through the skin (~33μg/cm(2)) compared to conventional liposomes, water dispersion, and a commercial gel.
International Journal of Pharmaceutics, 2016Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.
Journal of Cosmetic Dermatology, 2017
Why other moisturizers fit oily skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024
Ingredients
Sodium Hyaluronate, Acetyl Hexapeptide-8, Dipalmitoyl Hydroxyproline, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5, Ceramide Eop, Ceramide Np, Squalane, Cimicifuga Racemosa Root Extract Black Cohosh Root Extract, Saccharomyces Lysate Extract, Glyceryl Polymethacrylate, Jojoba Seed Oil, Argania Spinosa Oil Argan Oil, Plukenetia Volubilis Seed Oil, Butyrospermum Parkii Butter Shea Butter, Cetyl Alcohol, Tocotrienols Vitamin E, Tocopheryl Linoleate, Sodium Carboxymethyl Beta-Glucan, Vitis Vinifera Seed Extract Grape Seed Extract, Oenothera Biennis Oil, Rosa Canina Oil Rosehip Oil, Proprietary Blend Essential Oil, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.