# La Roche-Posay Toleriane Dermallergo Night Cream for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [La Roche-Posay](https://lovi.care/skincare/de/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your combination skin, this formula leverages niacinamide for seboregulation and glycerin for humectant action, effectively balancing oil production and hydration. Salicylic acid also offers moderate benefits for your acne, blemishes, and breakouts by supporting skin health.
- The presence of shea butter and squalane further enhances barrier function and provides excellent moisturizing effects, contributing to overall skin resilience.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/oily-acne-prone-skin): High

## Key ingredients

Thermal Water, Niacinamide, Squalane, Shea Butter, Allantoin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Users with ultra-sensitive, reactive, and allergy-prone skin frequently praise this night cream for its ability to instantly soothe redness and irritation without causing breakouts. While many appreciate the lightweight, gel-cream texture that absorbs quickly, those with extremely dry skin sometimes find it insufficiently moisturizing on its own, requiring an additional layer.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Safe for sensitive skin (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Hygienic packaging (sometimes noted)
- Disliked: Not hydrating enough (sometimes noted)
- Disliked: Adverse reactions (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Toleriane Dermallergo Night Cream a great fit for acne-prone skin?

This cream is a great fit because it balances oil production and keeps skin hydrated using niacinamide and glycerin. Ingredients like shea butter and squalane further help strengthen the skin barrier while offering great moisturizing effects with a very low risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for acne-prone skin?

This cream is a great fit for your skin because it features niacinamide to balance oil production along with squalane and shea butter to moisturize without feeling heavy. Its very safe formula is unlikely to cause any irritation.

### What does Thermal Water do for acne-prone skin?

Thermal water helps calm acne-prone skin by reducing irritation, redness, and dryness while supporting the skin barrier. It is unlikely to cause irritation and may improve overall skin comfort when used alongside your regular acne routine.
Sources: [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/), [Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37338719/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does it go in a skincare routine for acne-prone skin?

This moisturizing treatment is used at the end of your evening routine after your treatment step, and also as the final step in your morning routine before sunscreen. It helps hydrate and balance your skin while keeping the barrier strong, with virtually no risk of irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying the cream after your retinol step to help keep your skin calm and hydrated. This type of routine helps lower the chance of dryness and irritation while you use active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### How often should I use it?

You can use this moisturizing treatment daily in your evening routine. Regular application helps keep acne-prone skin balanced and hydrated without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is a great fit for acne-prone skin because it balances oil production and hydration while supporting the skin barrier with ingredients like niacinamide, squalane, and shea butter. It has an excellent safety profile without harsh ingredients, so it is unlikely to cause irritation or breakouts.

### Can I use it around the eyes or on my body?

This cream suits the thin skin around your eyes and your body well because its gentle ingredients keep the skin calm and safe from irritation. It is unlikely to cause any problems in these sensitive areas, maintaining good moisture without harsh effects.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €13.67 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/de/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — €36.14 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/de/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin) — High fit — €25.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €16.59 at Amazon
- SPF: [innisfree Daily UV Defense Mineral Sunscreen](https://lovi.care/skincare/de/p/innisfree/daily-uv-defense-mineral-sunscreen/for/acne-prone-skin) — Superior fit — €65.41 at Amazon

## Where to buy

- Amazon.de: €25.20 (https://www.amazon.de/dp/B0CNGTWLS7?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Water, Glycerin, Butylene Glycol, Propanediol, Butyrospermum Parkii Butter, Shea Butter, Pentylene Glycol, Squalane, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Pyridoxine Hcl, Polysorbate 20, Zea Mays Starch, Salvia Miltiorrhiza Root Extract, Allantoin, Glyceryl Acrylate, Acrylic Acid Copolymer, Sodium Hydroxide, Sphingomonas Extract Ferment, Hydroxyacetophenone, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Acetyl Dipeptide-1 Cetyl Ester, Xanthan Gum, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin
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- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/toleriane-dermallergo-night-cream/for/acne-prone-skin