# La Roche-Posay Toleriane Dermallergo Crème for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [La Roche-Posay](https://lovi.care/skincare/de/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your oily skin due to the presence of glycerin and hyaluronic acid, which hydrate and plump the skin, while niacinamide helps regulate sebum production and reduce inflammation, offering moderate benefits for acne, blemishes, and breakouts.
- The formula provides moderate suitability for oily skin by incorporating niacinamide for seboregulation and humectant action from glycerin, though it lacks stronger oil-controlling ingredients for optimal results.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Glycerin, Squalane, Niacinamide, Butyrospermum Parkii Butter Shea Butter, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other moisturizers fit oily acne-prone skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))

## What reviewers say

Users with dry, ultra-sensitive, and allergy-prone skin frequently praise this product for its deep hydration and immediate soothing of redness and irritation. It is also often noted as being safe for sensitive skin and absorbing quickly. Some users find the quantity to be small for the price and the packaging can be frustrating to empty completely.

- Liked: Calms redness (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Safe for sensitive skin (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Disliked: Expensive for quantity (sometimes noted)
- Disliked: Can feel drying (rarely noted)
- Disliked: Causes pilling (rarely noted)
- Disliked: Frustrating packaging (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Toleriane Dermallergo Crème work for oily acne-prone skin?

This moisturizer works moderately well for oily acne-prone skin, providing balanced hydration through glycerin and hyaluronic acid while niacinamide helps calm breakouts. It has a very safe formula with no irritation risks, though this skin type needs lighter, oil-controlling ingredients and barrier-supporting agents for optimal shine and blemish control.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Glycerin and hyaluronic acid hydrate your oily skin while niacinamide helps regulate oil production and calm blemishes. It is safe with no risk of irritation, but an oily acne-prone skin needs lighter oil-controlling ingredients and soothing extracts for optimal results.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Squalane do for oily acne-prone skin?

Squalane may help keep oily skin soft and smooth, but oxidized squalene can trigger inflammation in acne-prone skin. Because of this, oily acne-prone skin needs lightweight, non-greasy ingredients that balance moisture without clogging pores.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This cream goes as the third step in your morning routine after a cleanser and hydrating toner, and as the last step in your evening routine after makeup remover, cleanser, cleansing toner, and treatment. It provides moderate moisture and helps calm breakouts with ingredients like glycerin and niacinamide, though oily acne-prone skin often needs stronger oil-controlling ingredients for optimal results.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this cream with retinol, and it is best to apply the moisturizer after your retinol treatment to help soothe the skin. Using a moisturizer with retinol is unlikely to cause irritation and may help reduce dryness while supporting your skin barrier.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### How often should I use this cream?

You can use this cream twice a day as part of your morning and evening routine. Daily application helps keep your skin hydrated and is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to cause irritation or breakouts on your oily skin because it has a very safe formula with no harsh ingredients. However, to truly balance and manage oily acne-prone skin, a product needs stronger oil-controlling ingredients.

### Can I use this cream around the eyes or on my body?

You can use this cream around the eyes, though the skin there and on your body is much thinner than facial skin. The product is unlikely to cause irritation because it lacks harsh ingredients, but optimal results for thin areas may require targeted formulas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €13.67 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/de/p/belif/the-true-cream-aqua-bomb/for/oily-acne-prone-skin) — High fit — €36.14 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/de/p/anua/heartleaf-70-soothing-cream/for/oily-acne-prone-skin) — High fit — €25.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/de/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon

## Where to buy

- Amazon.de: €20.95 (https://www.amazon.de/dp/B09DPGJC3B?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €26.50 (https://www.notino.de/la-roche-posay/toleriane-dermallergo-feuchtigkeitscreme-fuer-empfindliche-haut/p-16095544/)
Prices checked 17 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Squalane, Pentylene Glycol, Butylene Glycol, Propanediol, Dimethicone, Niacinamide, Butyrospermum Parkii Shea Butter, Hyaluronic Acid, Polysorbate 20, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Citric Acid, Tocopherol, Ethylhexylglycerin, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin
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