# La Mer The Regenerating Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [La Mer](https://lovi.care/skincare/de/brands/la-mer)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your normal skin, as Algae Extract and Yeast Faex Extrait De Levure Extract support skin regeneration and provide antioxidant activity, but it lacks targeted ingredients to significantly address your redness and irritation concerns.
- The formulation includes beneficial ingredients like Saccharomyces Lysate Extract for skin renewal and soothing components such as Dipotassium Glycyrrhizate, which offer general hydration and comfort.
- The product is safe for your sensitive skin, containing no harsh ingredients and including soothing agents like Dipotassium Glycyrrhizate to minimize irritation risk.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Miracle Broth, Acetyl Hexapeptide-8, Niacinamide, Algae Extract, Glycerin

## What the research says

- Treatment with lipid algae extract reduced the level of oxidized proteins in human keratinocytes and stratum corneum skin cells. ([Annals of the New York Academy of Sciences, 2004](https://pubmed.ncbi.nlm.nih.gov/15247018/))
- Topical astaxanthin-loaded algae extract hydrogel and lipogel formulations exhibited the highest antioxidant activity and successful in vitro release, suggesting their potential as anti-aging formulations. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29745467/))
- Peptide fractions extracted from spent yeast waste streams are non-cytotoxic up to 500 µg/mL in HaCat and HDFa cells and positively modulate the production of skin metabolites including collagen, hyaluronic acid, fibronectin, and elastin. ([International Journal of Molecular Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/36768574/))
- A topical formulation containing panthenol, niacinamide, and dipotassium glycyrrhizate increased skin hydration by 74.1% and reduced transepidermal water loss by 13.5% at 28 days compared to baseline and untreated control in 35 individuals with xerosis. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Antarctic marine algae extracts increased cell viability, protected against inflammation, and enhanced the barrier integrity of human intestinal and keratinocyte cell lines damaged by lipopolysaccharide or ultraviolet radiation. ([Marine Drugs, 2022](https://pubmed.ncbi.nlm.nih.gov/36135751/))
- Treatment with bone marrow mesenchymal stem cells combined with Cystoseira algae extract significantly improved wound closure, tissue thickness, layer density, and skin elasticity while reducing oxidative indicators, pro-inflammatory cytokines, and immune markers in immunosuppressed rats compared to the control group. ([PloS One, 2024](https://pubmed.ncbi.nlm.nih.gov/38573954/))
- An algae extract prepared from Phaeodactylum tricornutum stimulated and protected proteasome peptidase activities and lowered protein oxidative damage in human keratinocytes exposed to UVA and UVB irradiation. ([Antioxidants & Redox Signaling, 2006](https://pubmed.ncbi.nlm.nih.gov/16487047/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))

## What reviewers say

Users with dry, mature, or sensitive skin frequently praise this serum for its immediate soothing and plumping effects, often noting a visible improvement in skin texture and radiance. Many experience hydration and a reduction in fine lines, though a significant portion of reviewers feel the anti-aging results do not justify the extremely high price point compared to other market alternatives.

- Liked: Deeply Hydrating (mostly mentioned)
- Disliked: Extremely High Price (mostly mentioned)
- Liked: Luxurious Feel (often mentioned)
- Liked: Smooths Skin Texture (often mentioned)
- Liked: Soothing & Calming (sometimes noted)
- Disliked: Poor Pump Design (sometimes noted)
- Disliked: Caused Breakouts/Irritation (rarely noted)
- Disliked: Strong Fragrance (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does La Mer The Regenerating Serum work for sensitive skin?

La Mer The Regenerating Serum works moderately well for sensitive skin, offering hydration and comfort with soothing components like dipotassium glycyrrhizate, but it lacks targeted ingredients to significantly address redness and irritation. To fit sensitive skin best, a treatment of this type needs effective ingredients that target redness and irritation, potent antioxidants, and hydrating components while posing no risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/), [International Journal of Molecular Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/36768574/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum fits sensitive skin because it contains soothing agents like dipotassium glycyrrhizate to help minimize irritation. To be a better fit for sensitive skin, a product of this type needs targeted ingredients that significantly address redness and irritation.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### What does Miracle Broth do for sensitive skin?

Miracle Broth is unlikely to irritate sensitive skin and helps keep it calm and comfortable. This type of product needs soothing ingredients and a gentle barrier-repairing formula to reduce redness and protect delicate skin.
Sources: [Marine Drugs, 2021](https://pubmed.ncbi.nlm.nih.gov/34436303/), [International Journal of Cosmetic Science, 2022](https://pubmed.ncbi.nlm.nih.gov/34813665/)

### What does Argireline do for sensitive skin?

Argireline is unlikely to cause irritation and is sometimes found in products designed to calm reactive skin. Studies show it helps smooth the look of wrinkles and decrease skin roughness when used consistently.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Pharmaceuticals, 2021](https://pubmed.ncbi.nlm.nih.gov/34451799/)

### Where does it go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Treatments with active ingredients are placed in the evening for simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to let it absorb, followed by your retinol. This product is unlikely to cause irritation on sensitive skin due to its soothing ingredients, though a product for this skin needs extra calming agents to properly manage redness.

### How often should I use it?

This treatment is applied in the evening as part of your routine for sensitive skin. Sensitive skin needs a product that includes calming agents and antioxidants to soothe irritation while supporting the skin.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin, as its safe formula includes soothing agents to minimize irritation. However, sensitive skin prone to breakouts or redness needs a treatment that includes targeted calming ingredients and oil-balancing components.

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, linalool, limonene, citronellol, and geraniol).

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/de/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/de/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/de/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €39.99 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/de/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €19.89 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/de/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — €18.00 at Amazon

## Where to buy

- Amazon.de: €387.00 (https://www.amazon.de/dp/B07X7NRNCY?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Algae Extract, Dimethicone, Hdi Trimethylol Hexyllactone Crosspolymer, Hydrogenated Polyisobutene, Caprylic Capric Myristic Stearic Triglyceride, Polysilicone-11, Peg-8 Dimethicone, Peg-10 Dimethicone, Yeast Faex Extrait De Levure Extract, Citrus Aurantifolia Peel Extract, Sigesbeckia Orientalis Extract, Polygonum Cuspidatum Root Extract, Saccharomyces Lysate Extract, Sesamum Indicum Seed Oil, Eucalyptus Globulus Oil Leaf Eucalyptus Oil Leaf, Sesamum Indicum Seed Powder, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake Sunflower Seedcake, Prunus Amygdalus Dulcis Seed Meal Seed, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Vitis Vinifera Seed Extract Grape Seed Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Punica Granatum Fruit Juice, Bupleurum Falcatum Root Extract, Citrus Reticulata Peel Extract Tangerine Peel Extract, Narcissus Tazetta Bulb Extract, Mimosa Tenuiflora Bark Extract, Betula Alba Bark Extract, Chlorella Vulgaris Extract, Humulus Lupulus Extract, Laureth-4, Corallina Officinalis Extract, Glycine Soja Seed Extract Soybean Seed Extract, Micrococcus Lysate, Whey Lactis Proteine Du Petit-Lait Protein, Tartaric Acid, Glycerin, Hydrolyzed Wheat Protein, Laureth-23, Butylene Glycol, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Sucrose, Coenzyme A, Acetyl Glucosamine, Caffeine, Dipalmitoyl Hydroxyproline, Linoleic Acid, Tetraacetylphytosphingosine, Alcaligenes Polysaccharides, Bifida Lysate Ferment, Pentylene Glycol, Dipotassium Glycyrrhizate, Palmitoyl Oligopeptide, Peg-8, Sorbitol, Tocopheryl Acetate, Eryngium Maritimum Extract, Sodium Hydroxide, Hydrogenated Lecithin, Hydroxypropyl Cyclodextrin, Nordihydroguaiaretic Acid, Cyclodextrin, Maltodextrin, Acetyl Hexapeptide-8, Glyceryl Polymethacrylate, Glycosaminoglycans, Gold, Tourmaline, Linolenic Acid, Silica, Ethylbisiminomethylguaiacol Manganese Chloride, Disodium Edta, Potassium Sorbate, Phenoxyethanol, Parfum, Hydroxycitronellal, Linalool, Limonene, Citronellol, Geraniol, Green 5 Ci 61570
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-mer/the-regenerating-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/sensitive-skin (this page)
- France: https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/la-mer/the-regenerating-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-mer/the-regenerating-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-mer/the-regenerating-serum/for/sensitive-skin