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HydroPeptide Power Serum for dry sensitive skin

HydroPeptide Power Serum
  • Palmitoyl Tripeptide-5
  • Hexapeptide-11
  • Acetyl Hexapeptide-30
  • Sodium Hyaluronate
  • Lemon Peel Extract

High

  • HighDry Skin Fit
  • HighEffectiveness
  • ExcellentSafety

A great choice for dry sensitive skin; a few serums fit it even better.

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Excellent for your dry and sensitive skin, this serum utilizes Hexapeptide-11 and Tetrahexyldecyl Ascorbate to effectively smooth texture and brighten your complexion. Glycerin and Sodium Hyaluronate are also included to provide essential hydration and support your skin's barrier function, addressing dryness and flakiness.
  • The inclusion of Tocopherol and various fruit extracts offers antioxidant protection and a soothing effect, further enhancing its suitability for sensitive skin.
  • This formula is safe for your skin, as it contains no harsh ingredients and is formulated with soothing components like Glycerin and Tocopherol.

How to apply

  • Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
  • Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
  • Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
  • Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
  • Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.

People Say

★4.8Overall rating based on 400+ reviews

Users consistently praise this serum as a lightweight, non-greasy anti-aging powerhouse that visibly plumps and smooths the skin. While it is highly effective for hydrating dry skin and softening fine lines without irritating sensitive complexions, the high price point and distinct scent are occasional points of contention.

Highlights

  • Lightweight texture Mostly Mentioned
    • “sinks right into skin”
    • “featherlight formula”
    • “perfect under makeup”
    • “no greasy residue”
  • Deep hydration Often Mentioned
    • “skin feels incredibly soft”
    • “visibly plumps”
    • “deeply hydrates without heaviness”
    • “glowing complexion”
  • Visible anti-aging Often Mentioned
    • “fine lines look reduced”
    • “skin feels firmer”
    • “years-younger appearance”
    • “unbelievable difference in 2 weeks”
  • High price point Often Mentioned
    • “a little pricey”
    • “worth the occasional splurge”
    • “wallet hurting”
  • Gentle on skin Sometimes Noted
    • “doesn't irritate my sensitive skin”
    • “calming peptides”
    • “no redness or breakouts”
    • “gentle formula”
  • Pleasant scent Sometimes Noted
    • “smells like heaven”
    • “hint of grapefruit”
    • “light and refreshing”
    • “smells like cucumbers”
  • Packaging size Rarely Noted
    • “1oz is too small”
    • “wish it was bigger”
    • “pump stopped working”
    • “expensive for the size”
  • Scent dislike Rarely Noted
    • “smell is a little off-putting”
    • “can't stand the scent”
    • “smells terrible”
    • “fragrance isn't for everyone”
  • Slow results Rarely Noted
    • “didn't see dramatic results”
    • “no huge difference”
    • “takes consistent use”
    • “wrinkles still there”

Sources: lovi.care, hydropeptide.com, dermstore.com, lovelyskin.com, youtube.com, wimj.com, and more

Questions and answers

What makes HydroPeptide Power Serum a great fit for dry sensitive skin?

HydroPeptide Power Serum is a great fit because it uses glycerin and sodium hyaluronate to bring in essential hydration and ease dryness and flakiness. It also features soothing ingredients and antioxidants like tocopherol to help calm sensitive skin while smoothing texture.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this serum a good fit for dry sensitive skin?

This serum is a great fit because it uses glycerin and sodium hyaluronate to quench dryness and flakiness, while hexapeptide-11 and tetrahexyldecyl ascorbic acid smooth texture and brighten your complexion. Tocopherol and fruit extracts add antioxidant protection and a soothing touch that keeps sensitive skin calm.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Palmitoyl Tripeptide-5 do for dry sensitive skin?

Palmitoyl Tripeptide-5 helps smooth fine lines and firms dry sensitive skin while boosting moisture. This ingredient is designed to improve how well the skin absorbs hydration and active ingredients safely.

Colloids and Surfaces. B, Biointerfaces, 2025

What does Hexapeptide-11 do for dry sensitive skin?

Hexapeptide-11 helps make dry, sensitive skin feel more firm and elastic by supporting its natural cellular repair and antioxidant defenses. Because it activates protective cell processes, it is unlikely to irritate easily, but dry skin of this type also needs rich soothing ingredients and gentle moisturizers to stay comfortable and smooth.

Redox Biology, 2015

Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in your evening routine after your cleansing and soothing steps, and before your moisturizer. Putting it in the evening helps provide extra safety around sun exposure.

Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it after your cleanser and soothing toner, and before your moisturizer. Using a soothing and hydrating serum like this one helps calm your skin and may reduce dryness and irritation from retinol.

Journal of Cosmetic Dermatology, 2024Clinical, Cosmetic and Investigational Dermatology, 2017

How often should I use this serum?

This serum is a great fit for your dry sensitive skin, and you can apply it in your evening routine. Using it then helps calm your skin and provides essential hydration while keeping your routine simple and safe around sun exposure.

Clinical, Cosmetic and Investigational Dermatology, 2017

Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts for dry sensitive skin. It features soothing ingredients like glycerin and tocopherol that help keep skin calm without heavy oils.

Clinical, Cosmetic and Investigational Dermatology, 2017

Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017
  • Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.

    Colloids and Surfaces. B, Biointerfaces, 2025
  • Hexapeptide-11 activated proteasome, autophagy, chaperones, and antioxidant response genes, protected fibroblasts against oxidative-stress-mediated premature cellular senescence, and improved skin elasticity in human subjects.

    Redox Biology, 2015
  • Hexapeptide-11 reversibly downregulated ATM and p53 protein expression in intrinsically aged fibroblasts, extrinsically aged fibroblasts, and extrinsically aged dermal papillae cells at concentrations between 0.1% and 1.0% in vitro, thereby influencing the onset of cellular senescence.

    Journal of Cosmetic Science, 2013
  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011
  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022
  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Butylene Glycol, Propanediol, Diethylhexyl Carbonate, Isopentyldiol, Pentylene Glycol, Diheptyl Succinate, Caprylyl Glycol, Hydroxyacetophenone, Olea Europaea Fruit Olive Fruit, Sodium Stearoyl Glutamate, Cetearyl Alcohol, Glyceryl Stearate, Potassium Olivoyl Hydrolyzed Oat Protein, Lysolecithin, Sclerotium Gum, Hexapeptide-11, Tetrahexyldecyl Ascorbate, 1,2-Hexanediol, Capryloyl Glycerin Sebacic Acid Copolymer, Phenylpropanol, Sorbitan Laurate, Pullulan, Xanthan Gum, Caprylic Capric Triglyceride, Glyceryl Oleate, Glycine Soja Seed Extract Soybean Seed Extract, Anogeissus Leiocarpus Bark Extract, Lemon Peel Extract, Palmitoyl Hexapeptide-19, Sodium Phytate, Hydroxyethylcellulose, Sodium Hyaluronate, Acetyl Dipeptide-1 Cetyl Ester, Citrus Aurantium Dulcis Peel Extract, Grapefruit Fruit Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Bergamot Fruit Extract, Citrus Aurantifolia Peel Extract, Citrus Nobilis Fruit Extract Mandarin Orange Fruit Extract, Tangerine Peel Extract, Acetyl Hexapeptide-30, Barosma Betulina Leaf Extract, Vanilla Planifolia Fruit Extract, Vitis Vinifera Fruit Extract Grape Fruit Extract, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Tocopherol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

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