# Good Molecules Niacinamide Serum for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Good Molecules](https://lovi.care/skincare/de/brands/good-molecules)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your dry and sensitive skin as niacinamide and glycerin provide hydration and barrier support, helping to improve skin texture and reduce the appearance of blemishes.
- The serum offers moderate pore-cleansing and skin-tone evening benefits, though it lacks sufficient emollient ingredients for optimal hydration for your dry skin.
- The safety profile is excellent due to the absence of harsh ingredients and the presence of soothing components like glycerin and betaine.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Glycerin, Dipropylene Glycol, Betaine, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine. ([Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/))
- A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical dry mouth products containing olive oil, betaine, and xylitol significantly increased unstimulated whole salivary flow rates, reduced xerostomia complaints, and improved quality of life in adults with polypharmacy-induced xerostomia compared to their normal routine care, with no clinically significant adverse events. ([Journal of Oral Rehabilitation, 2007](https://pubmed.ncbi.nlm.nih.gov/17824884/))
- Mixed surfactant systems of sodium dodecyl sulfate and dimethyl dodecyl amido betaine significantly reduce acute skin irritation potential in human volunteers compared with the individual surfactants, demonstrating that irritation potential cannot be predicted by simple summation. ([Food and Chemical Toxicology, 1998](https://pubmed.ncbi.nlm.nih.gov/9609395/))
- Polyhexanide/betaine may be nontoxic and effective in enhancing wound healing, whereas the majority of other topical cleaning agents are locally toxic and of limited or no proven efficacy. ([Advances in Skin & Wound Care, 2013](https://pubmed.ncbi.nlm.nih.gov/23507692/))

## Why other serums fit dry sensitive skin better

- Tocopherol succinate-loaded ethosomal gel increased skin deposition, stability, moisture, and mechanical properties in 13 human subjects compared to a control gel over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35274433/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))
- Hydrogels containing vitamin E-loaded nanostructured lipid carriers exhibited better occlusive properties and long-lasting effects, while vitamin E-loaded nanoemulsions performed a faster skin hydration effect and were selected as more attractive for skin application. ([Colloids and Surfaces. B, Biointerfaces, 2019](https://pubmed.ncbi.nlm.nih.gov/30974262/))

## What reviewers say

Based on a very large amount of data, this serum is highly regarded for its lightweight, non-sticky feel and its effectiveness in visibly reducing pores and smoothing skin texture, all at an accessible price. Many users found it beneficial for controlling oil and redness. A smaller number of users reported experiencing breakouts or irritation, indicating it might not be suitable for all sensitive skin types.

- Liked: Affordable price (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Minimizes pores (often mentioned)
- Liked: Controls oil/redness (sometimes noted)
- Liked: Elegant texture (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: No visible results (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Good Molecules Niacinamide work for dry sensitive skin?

Good Molecules Niacinamide Serum works moderately well for dry sensitive skin because niacinamide and glycerin help hydrate and support the skin barrier. While it is very safe and unlikely to cause irritation, a product of this type needs richer moisturizing and nourishing ingredients to provide optimal hydration and moisture retention for dry skin.
Sources: [Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Niacinamide and glycerin make this serum a good fit for dry sensitive skin by providing hydration and barrier support. Betaine further helps calm the skin and keeps irritation unlikely. To work best for dry skin, this type of product also needs richer smoothing ingredients for deep moisture.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### What does Glycerin do for dry sensitive skin?

Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in your evening routine after your toner and before your moisturizer. A product of this type needs extra rich and nourishing moisturizers to provide the deep hydration that dry skin needs.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol. Because this product is a moderate fit for dry sensitive skin, a routine for this skin type needs extra soothing and softening ingredients along with rich hydrating oils to keep your skin comfortable and fully moisturized.

### How often should I use this serum?

You can use this serum in the evening as part of your routine. This product works for your dry sensitive skin, though it lacks enough smoothing and softening ingredients for optimal hydration, so it needs extra rich moisturizers alongside it.

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

Good Molecules Niacinamide Serum may occasionally cause breakouts on dry sensitive skin, as some reviewers note, though its safety profile is otherwise good with soothing ingredients like glycerin and betaine. To truly prevent breakouts and keep dry skin comfortable, a product of this type needs richer, softening ingredients that lock in moisture and deeply nourish dry patches.
Sources: [Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/de/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — €169.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/de/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — €57.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — €9.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/de/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €19.89 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/de/p/torriden/dive-in-mild-sunscreen/for/dry-sensitive-skin) — Superior fit — €18.00 at Amazon

## Where to buy

- Amazon.de: €19.68 (https://www.amazon.de/dp/B08R994Q1L?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Niacinamide, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Betaine, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Ethylhexylglycerin, Polysorbate 60, Sorbitan Isostearate, Diphenyl Dimethicone, Disodium Edta, Triethylhexanoin, Polyglyceryl-10 Oleate, Hydrogenated Lecithin, Phenoxyethanol, Chlorphenesin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin (this page)
- France: https://lovi.care/skincare/fr/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin