# Good Molecules Gentle Retinol Cream for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Good Molecules](https://lovi.care/skincare/de/brands/good-molecules)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- This formulation offers moderate skin smoothing for your dry skin due to the presence of retinol and bakuchiol, which promote cell turnover and improve texture.
- Glycerin and Vitis Vinifera Seed Oil provide essential hydration and emollient actions, supporting dry or flaky skin without directly targeting the core issue.
- The product is safe for your dry skin, as it contains no prohibited or harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Bakuchiol, Glycerin, Acmella Oleracea Extract, Vitis Vinifera Seed Oil Grape Seed Oil

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- An all-natural anti-wrinkle emulsion serum containing Acmella oleracea extract demonstrated safe skin tolerability and reduced facial wrinkles in human volunteers after 2 weeks of application. ([International Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/34297422/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- Bakuchiol functions as an anti-aging compound through retinol-like regulation of gene expression, producing significant improvements in lines, wrinkles, pigmentation, elasticity, firmness, and photo-damage after 12 weeks of twice-a-day facial application without usual retinol therapy-associated undesirable effects. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24471735/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- An Acmella oleracea extract-loaded glycolipid emulsion serum applied topically demonstrated safety with no ocular irritation or systemic dermal absorption, alongside significant improvements in facial skin hydration, smoothness, and reductions in roughness, scaliness, and wrinkles. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39617635/))
- A novel formulation containing supramolecular retinol plus acmella oleracea extract significantly reduced dark circles by 13.8% in melanin index, decreased fine wrinkles, and increased skin firmness by 13.0% in 33 Chinese urban women after 6 weeks of use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34806292/))
- The optimized squalane-based spilanthol emulsion achieved a maximum skin retention of 118.71 μg/g and restored skin hydroxyproline content to 23.99 μg/g, outperforming positive and negative groups due to high drug release and miscibility driven by weak Van der Waals interactions. ([AAPS PharmSciTech, 2019](https://pubmed.ncbi.nlm.nih.gov/31222590/))
- Grapeseed oil-loaded dermocosmetic nanoemulgel applied on the cheeks of healthy volunteers significantly reduced skin melanin, erythema, sebum production, and pores while increasing moisture and elasticity compared to a placebo. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35713012/))
- Topical treatment with cranberry oil and grape oil improved wound healing in rats, with cranberry oil showing an 88.1% wound area reduction and grape oil showing 84.6% compared to 74.1% in controls and 78.4% in the mupirocin standard group on day 13. ([Phytotherapy Research, 2011](https://pubmed.ncbi.nlm.nih.gov/21305631/))
- An ionic liquid-based grapeseed oil emulsion increased transdermal penetration by 4.63-fold and improved skin hydration, firmness, elasticity, and facial wrinkles after 28 days of continuous use compared to ordinary emulsion. ([Pharmaceuticals, 2024](https://pubmed.ncbi.nlm.nih.gov/39458914/))

## What reviewers say

Based on a very large amount of data, this product is highly recommended as a gentle introduction to retinol, effectively improving skin texture and reducing fine lines without causing irritation. Users frequently report clearer skin and a more even tone. Some users find the formula too mild for significant anti-aging effects.

- Liked: Great price (mostly mentioned)
- Liked: Very gentle (mostly mentioned)
- Liked: Skin improvements (often mentioned)
- Liked: Clean ingredients (sometimes noted)
- Liked: Pleasant texture (sometimes noted)
- Disliked: Too mild (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Texture problems (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does the Gentle Retinol Cream work for dry skin?

This cream works moderately well for dry skin, as its retinol and bakuchiol smooth texture while glycerin and grape seed oil provide basic moisture. However, dry skin needs products rich in soothing, hydrating ingredients like niacinamide, ceramides, or peptides, along with barrier-supporting elements to keep it comfortable and nourished.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this cream a good fit for dry skin?

Glycerin and grape seed oil make this cream a good fit for dry skin by providing essential moisture and keeping flaky areas soft. To fit dry skin even better, a product of this type needs rich hydrating and barrier-supporting ingredients like ceramides, niacinamide, propolis, or peptides.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Retinol do for dry skin?

Retinol is a poor fit for dry skin because it frequently causes scaling, stinging, and dryness. To care for dry skin properly, a product needs gentle, hydrating ingredients like ceramides, glycerin, and hyaluronic acid to lock in moisture and keep the skin barrier calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### What does Bakuchiol do for dry skin?

Bakuchiol helps soothe sensitive dry skin while keeping it soft and smooth. It improves skin moisture content and barrier function while reducing redness and irritation.
Sources: [Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/), [Journal of Drugs in Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33346506/)

### Where does this cream go in a skincare routine for dry skin?

This cream goes in the evening routine after cleansing and before moisturizing, as treatments with active ingredients are best used then for simplicity and extra safety. To work best for dry skin, this type of product also needs rich hydrators and soothing oils to keep the skin soft and comfortable.

### Can I use this cream with vitamin C, and in what order?

You can use this cream and vitamin C in the same routine, but it is best to apply vitamin C in the morning and save this treatment for the evening to help prevent irritation. Because dry skin needs extra care when using active ingredients, this product needs added nourishing oils and rich hydrators to keep your skin smooth and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this cream?

You can use this treatment in the evening as part of your routine. This product type needs rich moisturizers and hydrating ingredients like hyaluronic acid or ceramides to properly care for dry skin.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to clog pores or cause breakouts for dry skin, and reviewers rarely mention any breakouts. However, ingredients like retinol may bring on mild temporary purging as they speed up cell renewal.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €9.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/de/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/de/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €18.50 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €19.75 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/de/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — €12.59 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/de/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

## Where to buy

- Amazon.de: €25.39 (https://www.amazon.de/dp/B09BST7MMP?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, C13-16 Isoparaffin, Glycerin, Diheptyl Succinate, Heptyl Undecylenate, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyglyceryl-10 Oleate, Propanediol, Vitis Vinifera Seed Oil Grape Seed Oil, Caprylic Capric Triglyceride, Bakuchiol, Tocopherol, Acmella Oleracea Extract, Butylene Glycol, Retinol, Allantoin, Helianthus Annuus Seed Oil Sunflower Seed Oil, Capryloyl Glycerin Sebacic Acid Copolymer, Ethylhexylglycerin, Willow Bark Extract, Camellia Sinensis Leaf Extract, Lilium Candidum Bulb Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/gentle-retinol-cream/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/good-molecules/gentle-retinol-cream/for/dry-skin (this page)
- France: https://lovi.care/skincare/fr/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/gentle-retinol-cream/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/good-molecules/gentle-retinol-cream/for/dry-skin