# Eucerin Hyaluron-Filler Epigenetic Serum for dry skin

**Lovi Fit: Warning fit for dry skin.**
Dry Skin Fit: Low · Effectiveness: Average · Safety: Risky.

Page: https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Eucerin](https://lovi.care/skincare/de/brands/eucerin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A poor match for dry skin; the moisturizers alongside fit it better.

## Why this fit

- Extremely low suitability for your dry skin due to the presence of alcohol denat, which can be drying, and a lack of sufficient emollient ingredients to counteract this effect.
- While glycerin and hyaluronic acid offer moderate hydration, the formula does not sufficiently address flakiness or provide specialized moisturizing ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin): Warning (this page)
- [Combination skin](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, users consistently report that the serum provides an immediate boost of hydration, leaving skin feeling significantly smoother, softer, and more radiant. While many observed a reduction in fine lines and a "plumped" effect within a few weeks, a small minority experienced skin irritation or felt the anti-aging results were not visible enough to justify the price.

- Liked: Lightweight, fast absorption (mostly mentioned)
- Liked: Layers well (often mentioned)
- Liked: Smoother, plumper skin (often mentioned)
- Liked: Pleasant, subtle scent (sometimes noted)
- Liked: Radiant, fresh glow (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Allergic reactions (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Scent too strong (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### Why does Lovi advise against Eucerin Hyaluron-Filler Epigenetic Serum for dry skin?

This serum has an extremely low suitability for dry skin due to alcohol denat, which can be drying, and a lack of enough rich, softening ingredients to counteract it. A moisturizing treatment for dry skin needs rich moisturizing agents and soothing ingredients like Centella Asiatica and Sodium Hyaluronate to effectively lock in moisture and address flakiness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a poor fit for dry skin?

Alcohol denat makes this serum a poor fit for dry skin because it can be drying. A moisturizing treatment for dry skin needs rich, nourishing ingredients and heavy moisturizers to lock in hydration and stop flakiness.

### What does Water do for dry skin?

Drinking more water helps increase skin hydration and may reduce clinical signs of dryness and roughness, particularly for individuals with lower prior water consumption.
Sources: [Skin Research and Technology, 2018](https://pubmed.ncbi.nlm.nih.gov/29392767/)

### What does Glycerin do for dry skin?

Glycerin helps dry skin by drawing in moisture and keeping it locked in, which makes the skin feel much softer and smoother. It also supports your natural skin barrier to stop water from escaping easily. A product for dry skin needs extra ingredients like hyaluronic acid and soothing plant extracts to truly calm and hydrate dry patches.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/)

### Where does it go in a skincare routine for dry skin?

This product is a poor fit for dry skin because it contains alcohol, which can be drying, and lacks enough softening ingredients to keep your skin smooth and comfortable. A moisturizer of this type needs rich, nourishing oils and barrier-protecting ingredients to combat flakiness and keep dry skin soft. When used in a routine despite this warning, it goes in the evening after cleansing and before your main moisturizer.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this serum with retinol, and in what order?

This serum is a poor match for dry skin because it contains drying alcohol and lacks enough rich, softening ingredients to keep your skin smooth and comfortable. If you still choose to use it with retinol, apply the serum before your retinol product at night, but follow up with a deeply nourishing moisturizer to protect your skin barrier.

### How often should I use it?

This product is a poor fit for your dry skin because it contains alcohol, which can be drying, and lacks enough rich softening ingredients to keep your skin smooth and comfortable. A good moisturizing treatment for dry skin needs rich, softening ingredients and soothing moisturizers that lock in hydration and stop flakiness.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores or cause breakouts on dry skin since its main hydrators do not block pores. However, because it contains drying alcohol and lacks rich rich moisturizers, dry skin needs products packed with heavy oils or butters to stay smooth and comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use it around the eyes or on my body?

This product is not ideal for the thin skin around the eyes or on the body when you have dry skin because it contains drying alcohol without enough rich, softening ingredients to soothe flakiness.

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for dry skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/de/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-skin) — High fit — €17.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/de/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-skin) — High fit — €15.99 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/de/p/kiehl-s/midnight-recovery-concentrate/for/dry-skin) — Average fit — €54.78 at Amazon

## Routine for dry skin

### AM

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €19.75 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/de/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — €12.59 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/de/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon
- SPF: [Australian Gold Botanical Sunscreen SPF 30](https://lovi.care/skincare/de/p/australian-gold/botanical-lotion-spf-30/for/dry-skin) — Superior fit — €21.04 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/de/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — €10.97 at Amazon
- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €19.75 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €9.99 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/de/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/de/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — €10.97 at Amazon
- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €19.75 at Amazon
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/de/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — €19.00 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €9.99 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/de/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

## Where to buy

- Amazon.de: €39.35 (https://www.amazon.de/dp/B0DFMNQ9R9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €39.50 (https://www.notino.de/eucerin/hyaluron-filler-epigenetic-verjuengendes-anti-aging-serum-kosmetiktaeschchen/p-16338720/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Water, Glycerin, Alcohol Denat, Hyaluronic Acid, Epicelline, Panthenol, Glyceryl Glucoside, Sodium Hydroxide, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin (this page)
- France: https://lovi.care/skincare/fr/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin