# DRMTLGY Peptide Night Cream for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [DRMTLGY](https://lovi.care/skincare/de/brands/drmtlgy)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for sensitive skin.

## Why this fit

- This product offers excellent moisturizing and barrier support for your normal skin, as ceramides and multiple peptides work to enhance resilience and smooth texture, directly addressing your redness and irritation.
- The inclusion of Palmitoyl Tetrapeptide-7 and Ceramide EOP specifically aids in soothing and reinforcing your skin's natural barrier.
- The safety profile is excellent, with no risks of irritation for your sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Peptides, Ceramides, Shea Butter, Tocopherol Vitamin E, Allantoin

## What the research says

- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on a very large amount of data, this fragrance-free night cream is highly regarded for its rich yet non-greasy texture, providing deep hydration and plumping effects. Users frequently report improvements in skin texture, reduced fine lines, and a strengthened moisture barrier, making it suitable for sensitive and aging skin types. Some users find the jar packaging unhygienic, and a few with very dry skin may require additional moisture, while others note it can be too heavy for daytime use. Availability can also be a concern due to frequent sell-outs.

- Liked: Deep hydration (mostly mentioned)
- Liked: Gentle formula (often mentioned)
- Liked: Non-greasy texture (often mentioned)
- Liked: Anti-aging benefits (sometimes noted)
- Liked: Value for money (sometimes noted)
- Disliked: Jar packaging (sometimes noted)
- Disliked: Availability issues (rarely noted)
- Disliked: Not rich enough (rarely noted)
- Disliked: Too heavy for day (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes DRMTLGY Peptide Night Cream a great fit for sensitive skin?

DRMTLGY Peptide Night Cream is a great fit because it provides deep moisture and barrier support through ceramides and multiple peptides that help calm redness and soothe irritation. It has an excellent safety profile, meaning it is very unlikely to cause irritation on sensitive skin due to the lack of harsh ingredients.
Sources: [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Which ingredients make this cream a good fit for sensitive skin?

This cream is a great fit for sensitive skin because it contains ceramides and multiple peptides that help calm redness and irritation while strengthening your skin barrier. The formula also has a very low chance of causing irritation since it leaves out harsh or prohibited ingredients.
Sources: [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### What do Peptides do for sensitive skin?

Peptides help support the skin barrier and improve the feel of sensitive skin by encouraging firmness and a smooth look. When paired with soothing and hydrating ingredients, peptide products are generally well tolerated and unlikely to cause irritation.
Sources: [Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/), [Journal of Biomedical Materials Research, 1998](https://pubmed.ncbi.nlm.nih.gov/9457557/)

### What do Ceramides do for sensitive skin?

Ceramides help calm and strengthen sensitive skin by improving moisture barriers and reducing discomfort. Topical use is well tolerated and may significantly increase skin hydration while easing stinging or sensitive sensations.
Sources: [Archives of Dermatological Research, 2018](https://pubmed.ncbi.nlm.nih.gov/29728858/), [Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/)

### Where does this cream go in a skincare routine for sensitive skin?

This cream goes in the evening routine as a moisturizing treatment, applied after your soothing toner and before your moisturizer. It is a great fit for sensitive skin because it contains ceramides and multiple peptides that help calm redness and irritation while reinforcing your natural barrier with very low likelihood of irritation.
Sources: [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Can I use it with retinol, and in what order?

Yes, you can use this product with retinol by applying the moisturizer after your retinol treatment to help soothe and protect your skin. Using a barrier-supporting moisturizer alongside retinoids is unlikely to cause irritation and helps improve skin recovery.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

This cream is a great fit for your sensitive skin and is designed to be used in your evening routine. Daily application helps keep your skin calm and hydrated while reinforcing its natural barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can it clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts on sensitive skin, as it has a very safe formula with no harsh or irritating ingredients. It helps keep skin calm and smooth without triggering reactions.
Sources: [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Can I use this cream around the eyes or on my body?

This cream is a great fit for your sensitive skin because it provides deep moisture and barrier support without harsh ingredients. It helps calm redness and irritation, and its gentle formula is safe to use on delicate areas like around the eyes or on the body.
Sources: [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/de/p/belif/the-true-cream-aqua-bomb/for/sensitive-skin) — High fit — €36.14 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/sensitive-skin) — High fit — €13.67 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/de/p/the-ordinary/natural-moisturizing-factors-ha/for/sensitive-skin) — High fit — €11.50 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €39.99 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/de/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €19.89 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/de/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — €18.00 at Amazon

## Where to buy

No store in Germany has a checked price for this product, so the page shows none.

## Ingredients

Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter Shea Butter, Caprylic Capric Triglyceride, Cetyl Alcohol, Dimethicone, Peg-100 Stearate, Ceramide Eop, Ceramide Ap, Palmitoyl Tetrapeptide-7, Ceramide Np, Palmitoyl Tripeptide-1, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Allantoin, Phytosphingosine, Cholesterol, Tridecane, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Glycol Distearate, Ethylhexylglycerin, Potassium Cetyl Phosphate, Carbomer, Sodium Hydroxide, Disodium Edta, Sodium Lauroyl Lactylate, Polysorbate 20, Dextran, Xanthan Gum, Phenoxyethanol, Magnesium Chloride
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/sensitive-skin (this page)
- France: https://lovi.care/skincare/fr/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/drmtlgy/peptide-night-cream/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/drmtlgy/peptide-night-cream/for/sensitive-skin