# DRMTLGY Peptide Night Cream for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [DRMTLGY](https://lovi.care/skincare/de/brands/drmtlgy)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your oily skin due to humectants like glycerin and propanediol, but lacks strong seboregulation for your primary concerns of acne, blemishes, and breakouts.
- The presence of ceramides and peptides enhances barrier resilience and provides excellent moisturizing benefits, supporting overall skin health.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Peptides, Ceramides, Shea Butter, Tocopherol Vitamin E, Allantoin

## What the research says

- Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A mixture of propanediol, xylitol, and caprylic acid demonstrated in vitro antimicrobial activity against C. acnes and S. aureus, reduced 5-alpha reductase expression, and decreased skin oiliness, porphyrin, and inflammatory lesions in participants over 28 days. ([Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## Why other moisturizers fit oily acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

Based on a very large amount of data, this fragrance-free night cream is highly regarded for its rich yet non-greasy texture, providing deep hydration and plumping effects. Users frequently report improvements in skin texture, reduced fine lines, and a strengthened moisture barrier, making it suitable for sensitive and aging skin types. Some users find the jar packaging unhygienic, and a few with very dry skin may require additional moisture, while others note it can be too heavy for daytime use. Availability can also be a concern due to frequent sell-outs.

- Liked: Deep hydration (mostly mentioned)
- Liked: Gentle formula (often mentioned)
- Liked: Non-greasy texture (often mentioned)
- Liked: Anti-aging benefits (sometimes noted)
- Liked: Value for money (sometimes noted)
- Disliked: Jar packaging (sometimes noted)
- Disliked: Availability issues (rarely noted)
- Disliked: Not rich enough (rarely noted)
- Disliked: Too heavy for day (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does DRMTLGY Peptide Night Cream work for oily acne-prone skin?

This cream works moderately well for oily skin since it provides good moisture, but it lacks oil-controlling ingredients to manage breakouts. An ideal product for this skin type needs lightweight hydration, barrier-supporting ingredients like ceramides, and blemish-clearing components that do not add excess oil.
Sources: [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Glycerin and propanediol make this cream a good fit for oily skin by providing moderate hydration and supporting the moisture barrier. However, because this product is an average fit, a product of this type for oily acne-prone skin needs powerful hydrating and repairing ingredients that clear blemishes without adding excess oil, along with ingredients that control oil and do not clog pores.
Sources: [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What do Peptides do for oily acne-prone skin?

Peptides help calm oily, acne-prone skin by targeting acne-causing bacteria and reducing redness and swelling. Advanced delivery methods like nanomicelles may also improve how deeply these helpful ingredients sink into the skin.
Sources: [Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/), [Bioorganic Chemistry, 2025](https://pubmed.ncbi.nlm.nih.gov/40925226/)

### What do Ceramides do for oily acne-prone skin?

Ceramides help restore the protective barrier of oily, acne-prone skin, which often lacks these vital lipids and suffers from moisture loss and irritation. Using products with ceramides supports skin hydration, calms redness, and improves overall texture while managing breakouts.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41749022/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37605504/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This moisturizing treatment goes at the end of your evening routine, right after your treatment step. Oily acne-prone skin needs a product of this type that also balances oil and targets blemishes.

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol in your evening routine by applying your retinol first and following it with the moisturizer. This cream helps keep your skin soft and comfortable while you use retinol, though oily acne-prone skin needs a moisturizer that also targets excess oil and breakouts.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this cream daily, applying it as part of your regular moisturizing routine. It helps keep your skin soft and comfortable while supporting your skin barrier, though oily skin of this type needs added oil-controlling ingredients and blemish-fighting actives to manage breakouts effectively.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to cause irritation or breakouts on your oily skin due to its gentle ingredients, but it may feel a bit heavy and lacks strong oil-control ingredients. For an ideal fit with oily acne-prone skin, a moisturizer needs ingredients that balance oil production and clear blemishes.

### Can I use this cream around the eyes or on my body?

You can use this cream around your eyes and on your body, as its gentle formula is well tolerated by different skin areas. While the thin skin around the eyes and various body regions benefit from rich moisturizers, oily skin generally needs a lighter texture and oil-controlling ingredients for targeted care in those areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €13.67 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/de/p/belif/the-true-cream-aqua-bomb/for/oily-acne-prone-skin) — High fit — €36.14 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/de/p/anua/heartleaf-70-soothing-cream/for/oily-acne-prone-skin) — High fit — €25.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/de/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon

## Where to buy

No store in Germany has a checked price for this product, so the page shows none.

## Ingredients

Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter Shea Butter, Caprylic Capric Triglyceride, Cetyl Alcohol, Dimethicone, Peg-100 Stearate, Ceramide Eop, Ceramide Ap, Palmitoyl Tetrapeptide-7, Ceramide Np, Palmitoyl Tripeptide-1, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Allantoin, Phytosphingosine, Cholesterol, Tridecane, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Glycol Distearate, Ethylhexylglycerin, Potassium Cetyl Phosphate, Carbomer, Sodium Hydroxide, Disodium Edta, Sodium Lauroyl Lactylate, Polysorbate 20, Dextran, Xanthan Gum, Phenoxyethanol, Magnesium Chloride
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/drmtlgy/peptide-night-cream/for/oily-acne-prone-skin