# CLIV PHA Mild Enzyme Powder for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: CLIV
Category: [Exfoliants](https://lovi.care/skincare/de/best/exfoliators)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few products fit it even better.

## Why this fit

- Offers excellent exfoliation for your acne and blemishes due to high concentrations of papain and bromelain, which provide enzymatic cleansing and texture smoothing, complemented by humectants like sodium hyaluronate and glycerin for hydration suitable for your combination skin.
- Lactobacillus Punica Granatum Extract Fruit Ferment and Portulaca Oleracea Extract offer additional soothing and antioxidant benefits, further supporting your skin's health.
- The formula is safe for your acne-prone skin, containing soothing ingredients like allantoin and sodium hyaluronate with no harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/oily-acne-prone-skin): High

## Key ingredients

Papain, Bromelain, Gluconolactone, Sodium Hyaluronate, Allantoin

## What the research says

- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Facial masks containing low-temperature extracted Portulaca oleracea protect sensitive skin from photothermal stimulation and improve skin barrier function during photorejuvenation. ([Cutaneous and Ocular Toxicology, 2025](https://pubmed.ncbi.nlm.nih.gov/41182319/))
- Portulaca oleracea extract ameliorated skin barrier damage and inflammation induced by combined exposure to glycolic acid and UVB in HaCaT cells. ([Cutaneous and Ocular Toxicology, 2022](https://pubmed.ncbi.nlm.nih.gov/35920724/))
- Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo. ([Wilderness & Environmental Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26827260/))
- Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/31991676/))
- Carica papaya leaf extracts obtained via supercritical fluid and conventional methods demonstrated antioxidant and cytoprotective effects on skin fibroblasts against oxidative stress, driven by their respective lipophilic and hydrophilic constituents. ([Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/33803330/))
- Oral bromelain slightly reduced pain compared to controls (mean difference -0.27) and topical bromelain reduced time to complete debridement by 6.89 days, with no major health risks reported. ([Nutrition and Health, 2023](https://pubmed.ncbi.nlm.nih.gov/37157782/))
- An upcycled pineapple leaf fibre crosspolymer forms a physical barrier that protects against environmental aggressors while providing antioxidant, anti-inflammatory, antipollution, UV protection, hydration, and hair benefits. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/41524117/))
- A coaxial electrospun core-shell nanofiber scaffold delivering bromelain and salvianolic acid B demonstrated sustained drug release, in vitro endothelial cell migration, increased capillary formation in an in ovo assay, and in vivo efficacy for skin regeneration and wound healing. ([Biomedical Materials, 2017](https://pubmed.ncbi.nlm.nih.gov/28580904/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects. ([The British Journal of Dermatology, 1997](https://pubmed.ncbi.nlm.nih.gov/9470910/))
- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on limited data, this enzyme powder is highly praised for its ability to gently exfoliate and deeply cleanse the skin without causing irritation or dryness. Users with sensitive and mixed skin types report that it effectively removes impurities and makeup, leaving the skin feeling exceptionally smooth, soft, and hydrated.

- Liked: Non-stripping cleanse (mostly mentioned)
- Liked: Gentle exfoliation (often mentioned)
- Liked: Skin texture improvement (often mentioned)
- Disliked: Limited availability (often mentioned)
- Liked: Suitable for sensitive skin (sometimes noted)
- Disliked: Price point (sometimes noted)
- Disliked: Messy application (rarely noted)
- Disliked: Potential irritants (rarely noted)

## How to apply

- Could be used as part of your weekly routine. Start by using the enzyme powder exfoliant once a week and increase only if your skin tolerates it well.
- Apply the enzyme powder exfoliant after cleansing and before using a hydrating toner or your mask. This ensures the product works effectively on clean skin.
- Mix the enzyme powder exfoliant with a little water in your hands to create a gentle foam . Gently massage it onto your face while avoiding any harsh rubbing.
- Apply the enzyme powder exfoliant on slightly damp skin to help with gentle activation and even distribution. Make sure to rinse thoroughly with lukewarm water afterwards.
- Always avoid the delicate eye area when applying the enzyme powder exfoliant. Do a patch test before your first use to check for any sensitivity.
- Video: https://storage.pora.ai/767f9b79c33b777aa28f84f66e309d62.mp4

## Questions and answers

### What makes CLIV PHA Mild Enzyme Powder a great fit for acne-prone skin?

CLIV PHA Mild Enzyme Powder is a great fit because it offers gentle yet effective cleansing for acne and blemishes using papain and bromelain to smooth texture. It also helps hydrate and calm the skin with sodium hyaluronate, glycerin, allantoin, and portulaca oleracea extract.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this exfoliant a good fit for acne-prone skin?

Papain and bromelain make this exfoliant a great fit for your acne-prone skin by providing gentle enzymatic cleansing and smoothing rough texture. They work alongside sodium hyaluronate and glycerin to hydrate, while allantoin and portulaca oleracea extract help soothe the skin.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Papain do for acne-prone skin?

Papain helps clear acne-prone skin by gently removing dead cells and targeting blemishes as part of a targeted treatment gel used daily. However, it may cause mild redness or irritation, and since it can disrupt the skin barrier, acne-prone skin also needs soothing, barrier-repairing ingredients to stay calm and protected.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [The Journal of Investigative Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25705851/)

### What does Bromelain do for acne-prone skin?

Bromelain helps calm acne-prone skin by reducing swelling and irritation. This ingredient may also support clearer skin through its anti-inflammatory properties.
Sources: [Molecular Carcinogenesis, 2012](https://pubmed.ncbi.nlm.nih.gov/21432909/), [Journal of Ethnopharmacology, 1988](https://pubmed.ncbi.nlm.nih.gov/3287010/)

### Where does this exfoliant go in a skincare routine for acne-prone skin?

Use this enzyme powder once a week in your evening routine after a makeup remover and cleanser, followed by a hydrating toner, treatment, and moisturizer. Start slowly once a week, and if your skin tolerates it well and shows good results, you may carefully use it more often.

### Can I use this exfoliant with retinol, and in what order?

Yes, you can use this exfoliant in your weekly routine, but avoid applying it on the same nights you use a strong retinol treatment to prevent irritation. Instead, use the enzyme powder on its designated weekly exfoliation night after cleansing, and follow with your regular hydrating toner and moisturizer.

### How often should I use this exfoliant?

You can start using this enzyme powder once a week as part of your routine. People who tolerate it well and see good results may carefully use it more often.

### Can this exfoliant clog pores, cause breakouts or purging for acne-prone skin?

This exfoliant is a great fit because it helps smooth texture and clear blemishes safely without clogging pores or causing harsh irritation. It includes soothing ingredients that help keep acne-prone skin calm and hydrated.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this exfoliant fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Dermalogica Daily Microfoliant](https://lovi.care/skincare/de/p/dermalogica/daily-microfoliant/for/acne-prone-skin) — Superior fit — €48.55 at Amazon
- [Good Molecules Pineapple Exfoliating Powder](https://lovi.care/skincare/de/p/good-molecules/pineapple-exfoliating-powder/for/acne-prone-skin) — High fit — €87.54 at Amazon
- [Dermalogica Daily Superfoliant](https://lovi.care/skincare/de/p/dermalogica/daily-superfoliant/for/acne-prone-skin) — High fit — €77.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €16.59 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €13.67 at Amazon

## Where to buy

No store in Germany has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Sodium Palmitate, Diglycerin, Allantoin, Maltodextrin, Papain, Bromelain, Gluconolactone, Sodium Hyaluronate, Lauryl Betaine, Sodium Chloride, Lactobacillus Punica Granatum Extract Fruit Ferment, Portulaca Oleracea Extract, Rosa Multiflora Fruit Extract, Ceratonia Siliqua Fruit Extract, Chenopodium Quinoa Seed Extract, Lens Esculenta Fruit Extract, Nelumbo Nucifera Seed Extract, Glycerin, 1,2-Hexanediol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin