# Caudalie Vinoperfect Radiance Serum for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: High · Safety: Low Risk.

Page: https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Caudalie](https://lovi.care/skincare/de/brands/caudalie)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your acne, blemishes, and breakouts due to Palmitoyl Grapevine Shoot Extract providing mild exfoliation and antioxidant support, while glycerin offers humectant action for your combination skin, though it lacks sufficient ingredients for optimal oil control on oily areas.
- The serum provides excellent brightening and evening of skin tone, enhancing your skin's radiance.
- The product is generally safe for your combination skin, with a low risk of irritation from citric acid.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Viniferine, Palmitoyl Grapevine Shoot Extract, Squalane, Glycerin, Tocopheryl Acetate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Daily treatment with a facial serum containing multiple acids reduced post-inflammatory hyperchromia lesion grade and number by 29.4% at 56 days, and decreased skin oiliness by 30.7% at 7 days in Brazilian patients with acne vulgaris. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/))
- A combination of Vitis vinifera shoot extract and a biotechnological extract demonstrated significant in vitro and in vivo antioxidant effects and improved clinical signs of photoaged skin in female subjects after a 4-week application. ([Journal of Drugs in Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17691204/))
- Pre-treatment with Vitis vinifera L. water extract (100 ΓΙg/mL) demonstrated antioxidant and scavenger activity against UV-A radiation and exerted an anti-mutagenic effect by maintaining apoptosis in UV-A and UV-B irradiated human keratinocytes (HaCaT). ([Journal of Photochemistry and Photobiology. B, Biology, 2020](https://pubmed.ncbi.nlm.nih.gov/32028189/))
- A water extract from grapevine leaves inhibited proinflammatory-induced interleukin-8 and vascular endothelial growth factor secretion in human keratinocytes compared to untreated challenged cells. ([Antioxidants, 2019](https://pubmed.ncbi.nlm.nih.gov/31100904/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))

## Why other serums fit acne-prone skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))

## What reviewers say

Based on a very large amount of data, this serum is highly regarded for its ability to gently brighten and even skin tone, making it a suitable option for sensitive skin and addressing concerns like dark spots and redness. Users frequently note its pleasant texture and hydrating finish, though it's important to note that consistent, long-term use is often required to see results. Some users also report a sticky sensation after application and find the product to be expensive.

- Liked: Brightens & evens tone (mostly mentioned)
- Liked: Gentle & non-irritating (mostly mentioned)
- Disliked: High price (mostly mentioned)
- Liked: Pleasant texture (often mentioned)
- Disliked: Slow results (often mentioned)
- Liked: Fresh scent (sometimes noted)
- Liked: Hydrating finish (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Rare breakouts (rarely noted)
- Disliked: Scent dislike (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Caudalie Vinoperfect Radiance Serum work for acne-prone skin?

Caudalie Vinoperfect Radiance Serum works moderately well for acne-prone skin by offering mild exfoliation and antioxidants, though it has a low risk of irritation and provides great brightening. To fit acne-prone skin best, a product of this type needs effective ingredients like niacinamide, zinc PCA, and propolis to balance oil and hydration.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/)

### Which ingredients make this serum a good fit for acne-prone skin?

Palmitoyl grapevine shoot extract helps by offering mild exfoliation and antioxidants for breakouts, and glycerin adds moisture for combination skin. To truly fit this skin well, a product of this type needs effective ingredients like niacinamide and zinc PCA to control oiliness while keeping skin balanced.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Viniferine do for acne-prone skin?

Viniferine helps calm acne-prone skin and fades dark spots left behind by breakouts. It is much gentler than vitamin C, making it less likely to cause irritation or redness on sensitive skin.

### Where does it go in a skincare routine for acne-prone skin?

Use this serum in the evening. It is generally safe for combination skin, though acne-prone skin needs ingredients for optimal oil control on oily areas.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol, but apply your retinol first and follow with this serum to help keep your skin comfortable. This product is generally safe for combination skin with a low risk of irritation, though acne-prone skin also needs ingredients for optimal oil control on oily areas.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use it?

You can use this treatment in your evening routine, applying it once a day or starting less often to see how your skin responds. A product of this type needs strong oil-controlling ingredients to properly balance acne-prone skin.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum works for acne-prone skin, though other products fit it better because it lacks sufficient ingredients for optimal oil control on oily areas. Acne-prone skin needs products with powerful oil-controlling and pore-clearing ingredients to stay clear.

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €9.99 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/de/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.29 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/de/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €16.59 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €13.67 at Amazon

## Where to buy

- Amazon.de: €63.90 (https://www.amazon.de/dp/B0D64WK4Z9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Coco-Caprylate Caprate, Squalane, Palmitoyl Grapevine Shoot Extract, Polyglyceryl-3 Distearate, Bisabolol, Glyceryl Stearate, Xanthan Gum, Caprylyl Glycol, Microcrystalline Cellulose, Polyacrylate Crosspolymer-6, Potassium Sorbate, Glyceryl Stearate Citrate, Citric Acid, Sodium Phytate, Sodium Hydroxide, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin