# Biossance Squalane + Copper Peptide Rapid Plumping Serum for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Biossance](https://lovi.care/skincare/de/brands/biossance)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for oily skin.

## Why this fit

- This serum offers excellent plumping for your oily skin, as sodium hyaluronate and copper tripeptide-1 provide deep hydration and improve elasticity without being occlusive. Acmella oleracea extract and ectoin further support skin hydration and resilience, beneficial for managing oily shine.
- The formula is highly compatible with oily skin due to humectants like glycerin and sodium hyaluronate, which hydrate without contributing to excess oiliness.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the inclusion of soothing agents like glycerin and Aloe Barbadensis Flower Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-acne-prone-skin): High

## Key ingredients

Squalane, Copper Peptides, Sodium Hyaluronate, Acmella Oleracea Extract, Panthenol

## What the research says

- An Acmella oleracea extract-loaded glycolipid emulsion serum applied topically demonstrated safety with no ocular irritation or systemic dermal absorption, alongside significant improvements in facial skin hydration, smoothness, and reductions in roughness, scaliness, and wrinkles. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39617635/))
- An all-natural anti-wrinkle emulsion serum containing Acmella oleracea extract demonstrated safe skin tolerability and reduced facial wrinkles in human volunteers after 2 weeks of application. ([International Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/34297422/))
- A novel formulation containing supramolecular retinol plus acmella oleracea extract significantly reduced dark circles by 13.8% in melanin index, decreased fine wrinkles, and increased skin firmness by 13.0% in 33 Chinese urban women after 6 weeks of use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34806292/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The optimized squalane-based spilanthol emulsion achieved a maximum skin retention of 118.71 μg/g and restored skin hydroxyproline content to 23.99 μg/g, outperforming positive and negative groups due to high drug release and miscibility driven by weak Van der Waals interactions. ([AAPS PharmSciTech, 2019](https://pubmed.ncbi.nlm.nih.gov/31222590/))
- Treatment with methanolic extract of Acmella oleracea leaves exerted potent antioxidant, anti-inflammatory, antimicrobial, and wound healing effects in vitro by reducing inflammatory mediators, scavenging free radicals, inhibiting bacterial growth, and enhancing fibroblast migration without inducing cytotoxicity. ([Journal of Ethnopharmacology, 2025](https://pubmed.ncbi.nlm.nih.gov/39357584/))
- Cellulose films incorporating Acmella oleracea depigmented extract and Achyrocline satureioides essential oil increased anesthesia time and wound contraction in in vivo tests compared to positive controls EMLA and allantoin, while also increasing collagen synthesis and epidermal thickening. ([Evidence-based Complementary and Alternative Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27777596/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))

## What reviewers say

Based on a very large amount of data, this serum is widely praised for its ability to deliver instant hydration and a visible plumping effect, making it a favorite for users with dry, dehydrated, or aging skin. The majority of users report a lightweight texture that absorbs well and improves skin bounce. A minority experience stickiness or find the high price point unjustifiable for the results achieved.

- Liked: Intense hydration (mostly mentioned)
- Liked: Elegant texture (often mentioned)
- Liked: Visible plumping (often mentioned)
- Liked: Improved texture (sometimes noted)
- Liked: Soothing properties (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Breakouts/Irritation (rarely noted)
- Disliked: Lack of results (rarely noted)
- Disliked: Paradoxical drying (rarely noted)
- Disliked: Sticky after-feel (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Biossance Squalane + Copper Peptide Rapid Plumping Serum a great fit for oily skin?

This serum is a great fit because sodium hyaluronate and copper tripeptide-1 provide deep hydration and elasticity without feeling heavy or greasy on oily skin. Glycerin and other humectants draw in moisture to keep your skin plump and smooth while helping to manage excess oily shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily skin?

This serum is a great fit for oily skin because sodium hyaluronate and glycerin hydrate deeply without feeling heavy or oily, while copper tripeptide-1 and acmella oleracea extract improve firmness and smoothness.
Sources: [International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39617635/), [International Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/34297422/)

### What does Squalane do for oily skin?

Squalane helps keep oily skin soft and smooth without feeling heavy, though oxidized forms may sometimes trigger irritation. To work well for oily skin, this type of product needs lightweight, non-clogging ingredients that balance moisture without adding excess grease.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### What do Copper Peptides do for oily skin?

Copper peptides help keep oily skin calm and balanced while improving firmness and smoothness. They support skin renewal and tissue repair, which may help reduce blemishes and large pores.
Sources: [International Journal of Molecular Sciences, 2018](https://pubmed.ncbi.nlm.nih.gov/29986520/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26091384/)

### Where does this serum go in a skincare routine for oily skin?

This serum goes in the evening routine, applied after cleansing and toning and before your moisturizer. Putting it in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate your oily skin and following it with retinol. This combination is unlikely to cause irritation because the formula is lightweight and free of heavy ingredients.

### How often should I use this serum?

You can use this serum in the evening as part of your routine. Some people may also use it in the morning or twice a day depending on how their skin feels and reacts. Daily application helps keep your skin hydrated and smooth while improving elasticity without adding extra oiliness.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts for your oily skin because it hydrates deeply without using heavy, pore-clogging ingredients. The formula's light hydrators and soothing agents keep your skin calm and balanced without adding extra shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

You can use this serum around the eyes, as its lightweight moisture and gentle ingredients are well tolerated on delicate skin, but it is typically reserved for facial use rather than the body. Studies show that similar hydrating and smoothing formulas are safe for the eye area and help reduce fine lines without irritation.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Allies of Skin Peptides & Antioxidants Firming Daily Treatment](https://lovi.care/skincare/de/p/allies-of-skin/peptides-and-antioxidants-firming-daily-treatment/for/oily-skin) — High fit — €92.00 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/de/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-skin) — High fit — €15.99 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/de/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-skin) — High fit — €17.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — €16.59 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/de/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — €32.80 at Amazon

## Where to buy

- Lookfantastic: €47.44 (https://www.lookfantastic.de/p/biossance-squalane-and-copper-peptide-rapid-plumping-serum-50ml/13643574/)
Prices checked 15 Oct 2026.

## Ingredients

Water, Glycerin, Propanediol, Squalane, Sodium Hyaluronate, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Copper Tripeptide-1, Acmella Oleracea Extract, Ectoin, Tetrapeptide-30, Palmitoyl Hexapeptide-52, Copper Pca, Panthenol, Sodium Polyglutamate, Camellia Sinensis Leaf Extract, Aloe Barbadensis Flower Extract, Passiflora Incarnata Flower Extract, Melia Azadirachta Leaf Extract, Solanum Melongena Fruit Extract, Curcuma Longa Root Extract, Ocimum Basilicum Leaf Extract Flower, Coccinia Indica Fruit Extract, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Citric Acid, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin (this page)
- France: https://lovi.care/skincare/fr/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
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- Netherlands: https://lovi.care/skincare/nl/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
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- Canada: https://lovi.care/skincare/ca/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/oily-skin