Biologique Recherche Crème Masque Vernix for acne-prone skin
Amniotic Fluid
Hydrolyzed Placental Protein
Ceramide Np
Squalane
Dimethylmethoxy Chromanol
Average
- AverageCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for acne-prone skin; other nourishing masks fit it better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- International Journal of Cosmetic Science, 2020
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your combination skin, as ingredients like Glycerin and Squalane provide essential hydration and emollient benefits, though it lacks strong seboregulation for your oily zones.
- The formulation provides general skincare benefits such as hydration and barrier enhancement through Amniotic Fluid and Lecithin, but it is not specifically targeted to address your acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.
How to apply
- You can use this creamy mask as part of your PM routine once a week. Start 3×/week if your skin tolerates it well.
- Apply the creamy mask after cleansing and toning, but always before your moisturizer .
- Smooth an even layer of the creamy mask over your face while avoiding any harsh rubbing. Let it sit ⏱ for the recommended time before rinsing.
- Apply the creamy mask on clean and dry skin for the best results against blemishes.
- Avoid the sensitive eye area and do a patch test before your very first use.
People Say
★4.0Overall rating based on 100+ reviewsBased on limited data, users describe this product as a "second birth" for the skin, effectively healing and repairing the moisture barrier for stressed, dry, or deficient complexions. The vegan formula plumps and shields the skin, though some users note it is less occlusive than the original version.
Highlights
Deep hydration Mostly Mentioned
- “Skin feels plump and nourished the next day”
- “Provides intense hydration for dry climates”
- “Leaves a soft, dewy finish”
Intense barrier repair Often Mentioned
- “Restores and strengthens the protective barrier”
- “Calms redness and irritation overnight”
- “Heals compromised skin barriers effectively”
Protective shield Often Mentioned
- “Acts like a protective shield against cold”
- “Feels like a seal locking everything in”
- “Perfect winter moisturizer”
Versatile application Often Mentioned
- “Great as an overnight sleeping mask”
- “Can be used as a daily moisturizer”
- “Works well applied thin or thick”
High price point Often Mentioned
- “Very expensive for the amount”
- “Hard to justify the price tag”
- “An investment product”
Sticky texture Often Mentioned
- “Feels sticky and tacky on the skin”
- “Can feel heavy if overapplied”
- “Leaves a greasy film”
Reformulation issues Sometimes Noted
- “Not as good as the original formula”
- “Miss the old animal-based version”
- “New VG formula feels different”
Unpleasant scent Sometimes Noted
- “Has a funky, yeasty smell”
- “Smell is peculiar but fades”
- “Not the best smelling product”
Sources: lovi.care, loshen.ca, aidabicaj.com, embassyofbeauty.co.uk, shoprescuespa.com, boutiqueskinenvie.com, and more
Questions and answers
How well does Crème Masque Vernix work for acne-prone skin?
Crème Masque Vernix is an average fit for acne-prone skin because while it provides good hydration and barrier support through ingredients like glycerin and squalane, it lacks targeted oil control and blemish-fighting properties. It has a very safe formula with no irritation risks, but acne-prone skin needs products of this type with soothing ingredients like niacinamide and centella asiatica to calm breakouts and balance oily zones.
Which ingredients make this cream a good fit for acne-prone skin?
This cream works for acne-prone skin because ingredients like Glycerin and Squalane provide essential hydration and barrier support, though other products fit it better. To provide a better fit for acne-prone skin, a product of this type needs soothing ingredients that address acne and breakouts, along with calming agents and ingredients like niacinamide or centella asiatica to manage blemishes without irritation.
What does Amniotic Fluid do for acne-prone skin?
Amniotic fluid is not a standard choice for acne-prone skin, as it may feel too heavy and risk clogging pores. Acne-prone skin generally needs lightweight ingredients that help clear blemishes and soothe irritation without adding excess oil.
What does Hydrolyzed Placental Protein do for acne-prone skin?
Hydrolyzed placental protein helps nourish skin cells and may support a clear, calm complexion without causing irritation. For acne-prone skin, a product of this type needs lightweight hydrators and soothing ingredients that do not clog pores.
Where does this cream go in a skincare routine for acne-prone skin?
This nourishing mask works for your skin, though other products fit it better because it lacks ingredients to control oil and breakouts. Acne-prone skin needs lightweight hydration, oil-balancing ingredients, and targeted blemish-fighting actives.
Can I use this cream with retinol, and in what order?
You can use this mask with retinol, applying it after your retinol treatment to help soothe dryness and keep your skin soft. This type of product needs ingredients that help balance oil and target breakouts to truly fit acne-prone skin.
How often should I use this cream?
This nourishing mask works for your acne-prone skin, though other products fit it better and it lacks targeted blemish control. To fit acne-prone skin well, a product of this type needs balancing ingredients that help control oil while keeping your skin calm.
Can this cream clog pores, cause breakouts or purging for acne-prone skin?
This cream is unlikely to cause irritation or make your acne-prone skin worse, as it has a very safe formula with no harsh ingredients. However, it is not specifically targeted to clear breakouts and lacks oil-controlling ingredients for oily zones, so acne-prone skin needs products with ingredients that balance oil and target blemishes.
Is this cream fragrance-free and alcohol-free?
It has no fragrance and contains drying alcohol (alcohol denat).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A novel water-in-oil emulsion with a lecithin-modified bentonite prevented epidermal degradation and inflammatory protein secretion induced by urban dust and cedar pollen more effectively than a conventional water-in-oil emulsion in a reconstructed human epidermis model.
International Journal of Cosmetic Science, 2020Purified and sterile human amniotic fluid successfully heals recalcitrant acne and sizeable abrasions of the face.
Annals of Case Reports, 2025Human amniotic fluid yields greater keratinocyte survival than saline and custodial solution in ex vivo full-thickness skin preservation at 4°C.
Annals of Plastic Surgery, 2013Amniotic fluid promotes accelerated re-epithelialisation in human skin wounds in vitro, an effect that is significantly impaired by the degradation of hyaluronic acid.
Journal of Plastic Surgery and Hand Surgery, 2013Topical placental extract increases epithelialisation by more than 50% in 67.5% of patients with chronic non-healing wounds compared to 23.3% in the control group over eight weeks.
Journal of Wound Care, 2004A cream containing horse placental extract significantly reduced the maximum wrinkle width and the number of wrinkles at the eye corners in healthy women compared to the untreated facial half over two weeks.
JMIR Dermatology, 2023Camellia japonica placenta extract treatment upregulated hair growth marker genes in human follicle dermal papilla cells in vitro and improved scalp moisture, sebum, keratin, and erythema in 42 adult female participants in vivo.
FEBS Open Bio, 2021Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Supplementation of a broad-spectrum sunscreen with Spirulina and dimethylmethoxy chromanol significantly improved skin pigmentation, reduced collagen degradation, and enhanced net elasticity in 44 healthy subjects after 84 days compared to sunscreen alone.
European Journal of Pharmaceutical Sciences, 2017
Why other nourishing masks fit acne-prone skin better
Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women.
Journal of Clinical Medicine, 2021
Ingredients
Water, Amniotic Fluid, Lecithin, Lanolin Oil, Propylene Glycol, Pentylene Glycol, Sodium Acrylates Copolymer, Glycerin, Alcohol Denat, Ethylhexyl Palmitate, Squalane, Raspberry Palm Aminopropanediol Esters Seed Oil Oil, Hydrolyzed Placental Protein, Hydrolyzed Gelatin, Yeast Extract, Hydrolyzed Ceratonia Siliqua Seed Extract, Phenoxyethanol, Sodium Lauroyl Lactylate, Sodium Dehydroacetate, Luffa Cylindrica Seed Oil, Tocopherol, Dimethylmethoxy Chromanol, Embryo Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Ethylhexylglycerin, Ceramide Np, Cholesterol, Potassium Sulfate, Ceramide Ap, Phytosphingosine, Papain, Xanthan Gum, Carbomer, Caprylyl Glycol, Diaminopropionoyl Tripeptide-33, Ceramide Eop
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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