# Biologique Recherche Crème Dermopurifiante for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Biologique Recherche](https://lovi.care/skincare/de/brands/biologique-recherche)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your combination skin, as niacinamide and enantia chlorantha bark extract help regulate sebum production to address oily shine.
- The formulation includes a variety of botanical extracts that provide soothing and anti-inflammatory benefits, though it may not offer the most potent treatment for all your concerns.
- The product is safe for your skin, with no indications of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Mimosa Tenuiflora Extract, Centella Asiatica Extract, Arnica Montana Extract, Salicylic Acid

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Chitosan/Mimosa tenuiflora bio-composite films exhibited improved thermal stability, increased water-uptake ability, antibacterial properties against Escherichia Coli and Micrococcus, and were non-toxic in cytotoxicity assays. ([International Journal of Biological Macromolecules, 2016](https://pubmed.ncbi.nlm.nih.gov/27693339/))
- Arabinogalactan-enriched fractions isolated from Mimosa tenuiflora bark significantly stimulated mitochondrial activity and proliferation in human primary dermal fibroblasts while having minor influence on HaCaT keratinocytes. ([Journal of Ethnopharmacology, 2009](https://pubmed.ncbi.nlm.nih.gov/19505559/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Gels containing 1% Arnica montana L. flower extract successfully enhanced the volume of the lips and face with a reduction of wrinkles in humans. ([International Journal of Cosmetic Science, 2023](https://pubmed.ncbi.nlm.nih.gov/35984685/))
- Topical application of Arnica montana ointment reduced the inflammatory response and oxidative damage in mice exposed to UVB radiation compared to untreated UVB-exposed skin. ([Cutaneous and Ocular Toxicology, 2020](https://pubmed.ncbi.nlm.nih.gov/32183539/))
- The protocol combining microcurrent with topical Arnica montana reduces inflammation, increases myofibroblast proliferation, and decreases macrophage presence in rats with skin lesions compared to controls. ([International Journal of Experimental Pathology, 2023](https://pubmed.ncbi.nlm.nih.gov/36752313/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))

## What reviewers say

Users with oily, acne-prone, and congested skin frequently report that this cream effectively regulates sebum and clears breakouts without causing dryness. The distinct, often-mentioned yeasty scent is a common drawback, but the majority of users find the balancing, purifying, and redness-reducing benefits outweigh this sensory aspect.

- Liked: Clears acne (mostly mentioned)
- Disliked: Unpleasant scent (mostly mentioned)
- Liked: Balances oil production (often mentioned)
- Disliked: High price (often mentioned)
- Liked: Hydrates without greasiness (sometimes noted)
- Liked: Refines texture (sometimes noted)
- Liked: Soothes redness (sometimes noted)
- Disliked: Initial reaction (rarely noted)
- Disliked: Reformulation concerns (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Biologique Recherche Crème Dermopurifiante work for combination skin?

Biologique Recherche Crème Dermopurifiante works moderately well for combination skin by helping regulate oily shine and calming the skin, though other products fit this skin type better. To achieve an ideal fit, combination skin needs effective balancing ingredients like niacinamide and zinc PCA that provide proper hydration without overwhelming oily areas or causing irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this cream a good fit for combination skin?

Niacinamide and enantia chlorantha bark extract make this cream a good fit for combination skin because they help regulate oiliness and manage shiny areas, while centella asiatica extract helps keep skin calm and hydrated. A treatment of this type needs a blend of balancing ingredients like niacinamide and zinc PCA to provide hydration without causing excess oiliness or dryness.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Mimosa Tenuiflora Extract do for combination skin?

Mimosa tenuiflora extract helps calm and repair dry or damaged areas on combination skin while supporting skin renewal. Because it is a weak fit for balanced combination zones, products for this skin type need lightweight hydrators and balancing ingredients to keep oily areas clear while soothing dry spots.
Sources: [Journal of Ethnopharmacology, 2009](https://pubmed.ncbi.nlm.nih.gov/19505559/), [Journal of Ethnopharmacology, 2007](https://pubmed.ncbi.nlm.nih.gov/17088036/)

### Where does this cream go in a skincare routine for combination skin?

This cream goes in your evening routine as a treatment step after cleansing and toning. Combination skin needs a product that helps balance oil production while keeping the skin calm with soothing botanical extracts.

### Can I use this cream with retinol, and in what order?

You can use this treatment alongside retinol by applying it after your retinol has fully absorbed into the skin. This helps minimize irritation while still allowing both products to work effectively.

### How often should I use this cream?

This treatment is used in the evening routine. A product of this type for combination skin needs ingredients like niacinamide and botanical extracts to help manage oily shine while keeping the skin calm and smooth.

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts on combination skin because it is safe and free of harsh ingredients. However, because it only offers moderate suitability, combination skin needs a treatment that combines sebum-regulating ingredients like niacinamide with potent botanical extracts to effectively balance oily shine without heavy textures.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — €9.99 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/de/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €35.29 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/de/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €333.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — €13.67 at Amazon

## Where to buy

No store in Germany has a checked price for this product, so the page shows none.

## Ingredients

Water, Propylene Glycol, Glycerin, Dicaprylyl Carbonate, Butylene Glycol, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Polyamide-5, Arctium Lappa Root Extract, Betula Alba Bark Extract, Enantia Chlorantha Bark Extract Moambe Jaune Bark Extract, Equisetum Arvense Extract, Mimosa Tenuiflora Bark Extract Acacia Decurrens Bark Extract, Hedera Helix Stem Extract Leaf, Fucus Vesiculosus Extract, Centella Asiatica Extract, Spiraea Ulmaria Extract, Arnica Montana Flower Extract, Rosa Canina Fruit Extract, Achillea Millefolium Extract Common Yarrow Extract, Aesculus Hippocastanum Seed Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Thymus Vulgaris Extract, Myrtus Communis Extract, Onion Bulb Extract, Commiphora Myrrha Extract Resin, Oleanolic Acid, Glycine Soja Oil Soybean Oil, Yeast Extract, Citric Acid, Tocopherol, Sodium Stearoyl Glutamate, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, Caprylyl Glycol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Sorbic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/combination-skin (this page)
- France: https://lovi.care/skincare/fr/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biologique-recherche/creme-dermopurifiante/for/combination-skin