BIOEFFECT EGF Serum for acne-prone skin
Rh-Oligopeptide-1
Glycerin
Sodium Hyaluronate
Hordeum Vulgare Seed Extract
Tromethamine
High
- HighCombination Skin Fit
- HighEffectiveness
- HighSafety
A great choice for acne-prone skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent skin regeneration for your acne, blemishes, and breakouts due to rh-oligopeptide-1 barley sh-oligopeptide-1 supporting skin regeneration and reducing inflammation.
- Highly suitable for your combination skin as glycerin and sodium hyaluronate provide humectant action, supporting hydration without exacerbating oiliness.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.
How to apply
- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.7Overall rating based on 600+ reviewsUsers with dry, mature, or dehydrated skin highly praise this serum for its deep hydration, plumping effects, and ability to reduce fine lines, resulting in a radiant complexion. Some users with oily or combination skin find the texture sticky or heavy.
Highlights
Hydrating and plumping Mostly Mentioned
- “Gives the skin an instant hydration boost! It's also great for plumping up the skin.”
- “It felt hydrating and plumping.”
- “Keeps my skin hydrated and plump.”
- “Thrilled with the glow and how well moisturized and smooth my skin looks.”
Radiant glow Often Mentioned
- “Gives my 62-year-old skin a beautiful glow!”
- “Skin looks radiant and is more resilient.”
- “Complexion has never looked more radiant or even-toned.”
- “As soon as the serum penetrates my skin, you can see the glow immediately.”
Reduces fine lines Often Mentioned
- “Visible minimizing effect on lines.”
- “Reduces the appearance of fine lines.”
- “Deep wrinkle under my eye that has pretty much disappeared!”
- “Visible improvement in the lines on my forehead.”
Expensive product Often Mentioned
- “Pity that it's so expensive, I'd definitely repurchase.”
- “Not the best for this price.”
- “Yes, it's an expensive product.”
- “Definitely an investment purchase.”
Improves texture Sometimes Noted
- “Skin looks more plumped, smooth and hydrated.”
- “Real difference in the texture of skin.”
- “Plumper, smoother and I can get away with minimal makeup.”
- “Makes my skin look so much smoother, even-toned and brighter.”
Sticky texture Sometimes Noted
- “It feels a bit sticky on the skin.”
- “Can still feel sticky on my skin.”
- “It feels like a film on my skin.”
- “Not absorbing during the night.”
Too heavy Rarely Noted
- “Might be too much for some skin types, especially during the warmer weather.”
- “Almost a little oily.”
- “I put it in the evening and it is not absorbing.”
Sources: lovi.care, dermstore.com, cultbeauty.com, bioeffect.com, beauty-detective.com, whowhatwear.com, and more
Questions and answers
What makes BIOEFFECT EGF Serum a great fit for acne-prone skin?
BIOEFFECT EGF Serum is a great fit because it helps regenerate skin and calm blemishes without causing irritation. Glycerin and sodium hyaluronate add hydration to the skin without making it oily.
Which ingredients make this serum a good fit for acne-prone skin?
This serum is a great fit for acne-prone skin because rh-oligopeptide-1 supports skin regeneration and helps reduce inflammation around breakouts. Additionally, glycerin and sodium hyaluronate provide hydration without adding extra oiliness, and the formula contains no harsh ingredients that might cause irritation.
What does EGF do for acne-prone skin?
EGF helps calm acne-prone skin by reducing both inflamed and non-inflamed breakouts. It supports skin healing and barrier repair, making it a useful option for improving overall skin texture.
What does Glycerin do for acne-prone skin?
Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
The British Journal of Dermatology, 2008International Journal of Toxicology, 2019
Where does it go in a skincare routine for acne-prone skin?
This treatment goes in the evening routine after cleansing and before moisturizing. Putting it at night keeps it simple and safe around sun exposure while helping your acne, blemishes, and breakouts.
Can I use this serum with retinol, and in what order?
Yes, you can use this serum with retinol by applying the serum first to support hydration and skin recovery, followed by your retinol. This approach helps maintain moisture and is unlikely to cause irritation on acne-prone skin.
How often should I use it?
Use this serum in the evening as part of your routine. It helps support skin regeneration and hydration without causing irritation or adding oiliness.
Can this serum clog pores, cause breakouts or purging for acne-prone skin?
This serum is unlikely to cause breakouts or clog pores on acne-prone skin because it relies on hydrating ingredients like glycerin and sodium hyaluronate that provide moisture without adding extra oiliness. It also features plant-based growth factors that help support skin renewal and calm inflammation safely.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Lidocaine at 20% and lidocaine 10% with trometamol provided effective pain control comparable to lidocaine/prilocaine in healthy adults after a 60-minute exposure, while propylene glycol did not accelerate the onset of analgesia.
Journal of Pain Research, 2017A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks.
Journal of Cosmetic Dermatology, 2020Ketorolac tromethamine poloxamer hydrogel provided sufficient bioavailability to reach the site of action with anti-inflammatory efficacy and no visual skin irritation in volunteers.
Pharmaceutical Research, 2017
Ingredients
Glycerin, Water, Sodium Hyaluronate, Tromethamine, Sodium Chloride, Hordeum Vulgare Seed Extract, Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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