# Anua PDRN Hyaluronic Acid Capsule 100 Serum for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Anua](https://lovi.care/skincare/de/brands/anua)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other moisturizers fit it better.

## Why this fit

- This serum offers excellent moisturizing benefits for your dry skin, with multiple forms of hyaluronic acid like Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate Crosspolymer providing deep hydration and improving elasticity.
- While Glycerin and other humectants support dry or flaky skin and sensitivity, specialized ingredients to directly target these concerns are not present.
- The product is safe for your dry and sensitive skin, as it lacks prohibited or harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-acne-prone-skin): High

## Key ingredients

Hydrolyzed Hyaluronic Acid, Niacinamide, Glutathione

## What the research says

- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Polyelectrolyte nanocomplexes of quaternized cyclodextrin grafted chitosan and low molecular weight hyaluronic acid improved skin texture and elasticity by increasing skin hydration in clinical evaluation. ([Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/))
- Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))

## Why other moisturizers fit dry sensitive skin better

- A dexpanthenol-containing cream accelerated skin barrier repair, increased stratum corneum hydration, reduced skin roughness, and decreased skin redness compared to vehicle and untreated controls in sodium lauryl sulphate-irritated skin. ([The Journal of Dermatological Treatment, 2002](https://pubmed.ncbi.nlm.nih.gov/19753737/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- A cream containing panthenol, prebiotics, and probiotic lysate improved facial sensitive skin symptoms and skin barrier function in 110 participants over 28 days. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38186043/))

## What reviewers say

Users consistently praise this serum for delivering the coveted "glass skin" look, offering deep hydration that plumps the skin without feeling heavy or greasy. While most find it excellent for barrier repair and instant glow, a minority feel it is simply a good hydrator rather than a "life-changing" treatment for the price.

- Liked: Deep hydration (mostly mentioned)
- Liked: Glass skin glow (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Makeup compatibility (sometimes noted)
- Liked: Soothing & repair (sometimes noted)
- Disliked: Price vs volume (sometimes noted)
- Disliked: Breakouts (rarely noted)
- Disliked: Runny consistency (rarely noted)
- Disliked: Subtle results (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Anua PDRN Hyaluronic Acid Capsule 100 Serum work for dry sensitive skin?

This serum works well to give your dry skin deep hydration, though a product of this type needs added soothing ingredients and barrier-supporting agents like pro vitamin B5 or ceramides to truly thrive.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Which ingredients make this serum a good fit for dry sensitive skin?

This serum fits your dry and sensitive skin because multiple forms of hyaluronic acid and glycerin provide deep hydration and help flaky areas stay soft and smooth. To be a better fit for this skin type, a product of this type needs additional soothing ingredients, ceramides, and pro vitamin B5 to strengthen the skin barrier and lock in moisture.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### What does Hydrolyzed Hyaluronic Acid do for dry sensitive skin?

Hydrolyzed hyaluronic acid helps keep dry sensitive skin hydrated and soft, while improving skin texture and comfort. Clinical studies show that regular use significantly boosts moisture levels and calms tightness with a very safe profile.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does it go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine after your toner and before your moisturizer. A product of this type needs soothing ingredients to calm irritation and rich moisturizers to properly care for dry skin.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it as your treatment step before your moisturizer in your evening routine. This helps keep your skin hydrated and is unlikely to cause irritation since the formula lacks harsh ingredients. A product of this type for dry sensitive skin needs soothing agents and barrier-strengthening ingredients to directly target sensitivity.

### How often should I use it?

You can use this serum in your evening routine daily. Daily application of moisturizers with hyaluronic acid helps keep dry skin hydrated and improves the skin barrier.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores, cause breakouts or trigger purging on your dry sensitive skin because it lacks harsh or irritating ingredients. It provides good basic hydration, though dry sensitive skin also needs specialized soothing ingredients and rich barrier-repairing elements to truly thrive.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Can I use it around the eyes or on my body?

You can use this serum around the eyes and on the body because its gentle formula is safe and unlikely to cause irritation. Products of this type need rich hydrators and soothing ingredients to properly comfort dry, sensitive skin.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/de/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-sensitive-skin) — Superior fit — €17.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/de/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-sensitive-skin) — High fit — €15.99 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/de/p/kiehl-s/midnight-recovery-concentrate/for/dry-sensitive-skin) — High fit — €54.78 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/de/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €19.89 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/de/p/torriden/dive-in-mild-sunscreen/for/dry-sensitive-skin) — Superior fit — €18.00 at Amazon

## Where to buy

- Amazon.de: €22.00 (https://www.amazon.de/dp/B0DSVF8HGZ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €18.40 (https://www.lookfantastic.de/p/anua-pdrn-hyaluronic-acid-capsule-100-serum-30ml/16674990/)
- Notino: €25.90 (https://www.notino.de/anua/pdrn-hyaluronic-acid-capsule-100-serum-feuchtigkeitsspendendes-serum-mit-ernaehrender-wirkung-mit-kollagen/p-16313399/)
Prices checked 16 Oct – 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Propanediol, Glycerin, Hydrolyzed Hyaluronic Acid, 1,2-Hexanediol, Niacinamide, Glyceryl Oleate, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Hydrogenated Lecithin, Glutathione, Hydrolyzed Collagen, Hyaluronic Acid, Coptis Japonica Root Extract, Adenosine, Sodium Dna, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Ocimum Sanctum Leaf Extract, Citric Acid, Curcuma Longa Root Extract, Corallina Officinalis Extract, Sodium Citrate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin (this page)
- France: https://lovi.care/skincare/fr/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin