# Phytosphingosine

Page: https://lovi.care/skincare/de/ingredients/phytosphingosine

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Phytosphingosine naturally clears breakouts, repairs the moisture barrier, and smooths fine lines for a healthy look. It suits dry skin and oily skin best, and comes in rich creams. This ingredient fits smoothly into a routine because it works well with [bio-placenta peptides](https://lovi.care/skincare/de/ingredients/bio-placenta-peptides), [hexapeptides](https://lovi.care/skincare/de/ingredients/hexapeptide), and [acetyl hexapeptide-3](https://lovi.care/skincare/de/ingredients/acetyl-hexapeptide-3).

[International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/) [Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/) [International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489360/)

This page shows phytosphingosine products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app.

### Popular phytosphingosine products

- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€8.85 at Amazon](https://www.amazon.de/dp/B07C5R51Q9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/dry-skin) — High fit — [€31.00 at Amazon](https://www.amazon.de/dp/B09YDCCJBJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/acne-prone-skin) — Superior fit — [€39.77 at Amazon](https://www.amazon.de/dp/B0CZD72G5W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Bioderma Atoderm Intensive Eye](https://lovi.care/skincare/de/p/bioderma/atoderm-intensive-eye/for/acne-prone-skin) — High fit — [€20.73 at Amazon](https://www.amazon.de/dp/B08562FW67?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/dry-sensitive-skin) — High fit
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/oily-skin) — High fit — [€83.90 at Amazon](https://www.amazon.de/dp/B01N5HLNB8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### Phytosphingosine creams

- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/dry-skin) — High fit — [€31.00 at Amazon](https://www.amazon.de/dp/B09YDCCJBJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/acne-prone-skin) — Superior fit — [€39.77 at Amazon](https://www.amazon.de/dp/B0CZD72G5W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/dry-sensitive-skin) — High fit
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/oily-skin) — High fit — [€83.90 at Amazon](https://www.amazon.de/dp/B01N5HLNB8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

## What reviewers say about popular phytosphingosine products

The highlight reviewers mention most for each popular phytosphingosine product on Lovi.

- CeraVe Hydrating Facial Cleanser Gentle and non-stripping ★4.6 · 85.0k+ reviews Hydrating formula Poor makeup removal “doesn't leave face tight” [What people say about Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/dry-skin)
- CeraVe PM Facial Moisturizing Lotion Lightweight & non-greasy ★4.6 · 60.0k+ reviews Fragrance-free & gentle Not moisturizing enough “Sinks right into your skin” [What people say about PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin)
- Aestura Atobarrier 365 Cream Long-lasting hydration ★4.7 · 3.0k+ reviews Soothing for sensitive Non-greasy finish “Skin still plump the next morning” [What people say about Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/dry-skin)
- Cetaphil Ceramide Serum Lightweight & non-greasy ★4.7 · 400+ reviews Effective hydration Soothing & gentle “absorbs beautifully without feeling greasy” [What people say about Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/acne-prone-skin)
- Bioderma Atoderm Intensive Eye Deeply hydrating ★4.7 · 300+ reviews Good makeup base Versatile use “Fixed my dry flaky eyelids” [What people say about Atoderm Intensive Eye](https://lovi.care/skincare/de/p/bioderma/atoderm-intensive-eye/for/acne-prone-skin)
- Obagi Rebalance Skin Barrier Recovery Cream Deeply hydrating ★4.6 · 400+ reviews Soothes irritated skin Great post-procedure “soaks right in” [What people say about Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/dry-sensitive-skin)

### Phytosphingosine for dry skin

- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€8.85 at Amazon](https://www.amazon.de/dp/B07C5R51Q9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/dry-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/dry-skin) — High fit — [€39.77 at Amazon](https://www.amazon.de/dp/B0CZD72G5W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/dry-skin) — High fit
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/dry-skin) — High fit — [€31.00 at Amazon](https://www.amazon.de/dp/B09YDCCJBJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/dry-skin) — High fit — [€83.90 at Amazon](https://www.amazon.de/dp/B01N5HLNB8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Bioderma Atoderm Intensive Eye](https://lovi.care/skincare/de/p/bioderma/atoderm-intensive-eye/for/dry-skin) — Average fit — [€20.73 at Amazon](https://www.amazon.de/dp/B08562FW67?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### Phytosphingosine for oily skin

- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/oily-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/oily-skin) — High fit — [€83.90 at Amazon](https://www.amazon.de/dp/B01N5HLNB8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/oily-skin) — High fit — [€39.77 at Amazon](https://www.amazon.de/dp/B0CZD72G5W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/oily-skin) — Average fit
- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/oily-skin) — Average fit — [€8.85 at Amazon](https://www.amazon.de/dp/B07C5R51Q9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Bioderma Atoderm Intensive Eye](https://lovi.care/skincare/de/p/bioderma/atoderm-intensive-eye/for/oily-skin) — Average fit — [€20.73 at Amazon](https://www.amazon.de/dp/B08562FW67?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/oily-skin) — Low fit — [€31.00 at Amazon](https://www.amazon.de/dp/B09YDCCJBJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### Phytosphingosine for combination skin

- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/combination-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/combination-skin) — High fit — [€39.77 at Amazon](https://www.amazon.de/dp/B0CZD72G5W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/combination-skin) — High fit — [€83.90 at Amazon](https://www.amazon.de/dp/B01N5HLNB8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/combination-skin) — High fit
- [Bioderma Atoderm Intensive Eye](https://lovi.care/skincare/de/p/bioderma/atoderm-intensive-eye/for/combination-skin) — Average fit — [€20.73 at Amazon](https://www.amazon.de/dp/B08562FW67?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/combination-skin) — Average fit — [€31.00 at Amazon](https://www.amazon.de/dp/B09YDCCJBJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/combination-skin) — Average fit — [€8.85 at Amazon](https://www.amazon.de/dp/B07C5R51Q9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### Phytosphingosine for sensitive skin

- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/sensitive-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/sensitive-skin) — Average fit
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/sensitive-skin) — Average fit — [€83.90 at Amazon](https://www.amazon.de/dp/B01N5HLNB8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/sensitive-skin) — Average fit — [€31.00 at Amazon](https://www.amazon.de/dp/B09YDCCJBJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/sensitive-skin) — Average fit — [€39.77 at Amazon](https://www.amazon.de/dp/B0CZD72G5W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Bioderma Atoderm Intensive Eye](https://lovi.care/skincare/de/p/bioderma/atoderm-intensive-eye/for/sensitive-skin) — Average fit — [€20.73 at Amazon](https://www.amazon.de/dp/B08562FW67?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/sensitive-skin) — Low fit — [€8.85 at Amazon](https://www.amazon.de/dp/B07C5R51Q9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### Phytosphingosine for acne-prone skin

- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/acne-prone-skin) — Superior fit — [€39.77 at Amazon](https://www.amazon.de/dp/B0CZD72G5W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Bioderma Atoderm Intensive Eye](https://lovi.care/skincare/de/p/bioderma/atoderm-intensive-eye/for/acne-prone-skin) — High fit — [€20.73 at Amazon](https://www.amazon.de/dp/B08562FW67?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/acne-prone-skin) — Average fit
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/acne-prone-skin) — Average fit — [€83.90 at Amazon](https://www.amazon.de/dp/B01N5HLNB8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/acne-prone-skin) — Average fit — [€8.85 at Amazon](https://www.amazon.de/dp/B07C5R51Q9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/acne-prone-skin) — Average fit — [€31.00 at Amazon](https://www.amazon.de/dp/B09YDCCJBJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### Phytosphingosine for mature skin

- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/mature-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/mature-skin) — High fit — [€39.77 at Amazon](https://www.amazon.de/dp/B0CZD72G5W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/mature-skin) — High fit — [€83.90 at Amazon](https://www.amazon.de/dp/B01N5HLNB8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Bioderma Atoderm Intensive Eye](https://lovi.care/skincare/de/p/bioderma/atoderm-intensive-eye/for/mature-skin) — High fit — [€20.73 at Amazon](https://www.amazon.de/dp/B08562FW67?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/de/p/obagi/rebalance-skin-barrier-recovery-cream/for/mature-skin) — High fit
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/de/p/aestura/atobarrier-365-cream/for/mature-skin) — Average fit — [€31.00 at Amazon](https://www.amazon.de/dp/B09YDCCJBJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/mature-skin) — Average fit — [€8.85 at Amazon](https://www.amazon.de/dp/B07C5R51Q9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

## What to combine phytosphingosine with

Ingredient Together How to use them

[Bio-placenta peptides](https://lovi.care/skincare/de/ingredients/bio-placenta-peptides) Works well Use them together in the same routine, applying the phytosphingosine first and following with the [bio-placenta peptides](https://lovi.care/skincare/de/ingredients/bio-placenta-peptides). [Phytosphingosine and bio-placenta peptides](https://lovi.care/skincare/de/ingredients/bio-placenta-peptides-and-phytosphingosine) [Hexapeptide](https://lovi.care/skincare/de/ingredients/hexapeptide) Works well Use them together by applying the [hexapeptide](https://lovi.care/skincare/de/ingredients/hexapeptide) first and the phytosphingosine right after, because lipids help the peptide absorb better. [Phytosphingosine and hexapeptide](https://lovi.care/skincare/de/ingredients/hexapeptide-and-phytosphingosine) [Acetyl hexapeptide-3](https://lovi.care/skincare/de/ingredients/acetyl-hexapeptide-3) Works well Use them together in the same routine, applying the peptide product first followed by the ceramide cream, for better barrier support. [Phytosphingosine and acetyl hexapeptide-3](https://lovi.care/skincare/de/ingredients/acetyl-hexapeptide-3-and-phytosphingosine) [Collagen peptide](https://lovi.care/skincare/de/ingredients/collagen-peptide) Works well Use them together in the same routine, applying the phytosphingosine first and the [collagen peptide](https://lovi.care/skincare/de/ingredients/collagen-peptide) right after for better skin absorption. [Phytosphingosine and collagen peptide](https://lovi.care/skincare/de/ingredients/collagen-peptide-and-phytosphingosine) [Copper peptide](https://lovi.care/skincare/de/ingredients/copper-peptide) Works well Use them together in the same routine, applying the [copper peptide](https://lovi.care/skincare/de/ingredients/copper-peptide) first and the phytosphingosine right after, because lipids help peptides absorb better. [Phytosphingosine and copper peptide](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-copper-peptide) [Hexapeptide-9](https://lovi.care/skincare/de/ingredients/hexapeptide-9) Works well Use them together in the same routine, applying the peptide first and following with the phytosphingosine. [Phytosphingosine and hexapeptide-9](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-hexapeptide-9) [Peptide-rich plasma](https://lovi.care/skincare/de/ingredients/peptide-rich-plasma) Works well Use them together in the same routine, applying the [peptide-rich plasma](https://lovi.care/skincare/de/ingredients/peptide-rich-plasma) first and the phytosphingosine right after to boost results. [Phytosphingosine and peptide-rich plasma](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-peptide-rich-plasma) [Triple peptide blend](https://lovi.care/skincare/de/ingredients/triple-peptide-blend) Works well Use them together in the same routine, applying the peptide blend first and the phytosphingosine right after to lock in moisture. [Phytosphingosine and triple peptide blend](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-triple-peptide-blend) [Palmitoyl pentapeptide-4](https://lovi.care/skincare/de/ingredients/palmitoyl-pentapeptide-4) Works well Use them together in the same routine, applying the peptide product first and following with the phytosphingosine cream, because they help each other repair the skin. [Phytosphingosine and palmitoyl pentapeptide-4](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-palmitoyl-pentapeptide-4) [Palmitoyl tripeptide-1](https://lovi.care/skincare/de/ingredients/palmitoyl-tripeptide-1) Works well Use them together in the same routine, applying the lipid component first followed by the peptide cream, because lipids help skin absorb peptides better. [Phytosphingosine and palmitoyl tripeptide-1](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-palmitoyl-tripeptide-1)

From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app.

## Questions and answers

### What does phytosphingosine do for the skin?

Phytosphingosine helps fight acne by reducing microbes and inflammation, and it may improve skin hydration and barrier recovery. It also helps repair photoaged skin by supporting [collagen](https://lovi.care/skincare/de/ingredients/collagen) production and reducing wrinkles.

[International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/) [Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/)

### How do you use phytosphingosine?

You can use phytosphingosine topically to help soothe the skin and repair its natural barrier. It works well when combined with various peptides in your routine, often applied either before or after depending on the specific peptide pairing.

[International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/) [Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/)

### Should you use phytosphingosine in the morning or at night?

You can use phytosphingosine in your routine day or night. It helps repair the skin barrier and soothe inflammation.

[International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/) [Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/)

### Can you use phytosphingosine every day?

Yes, you can use phytosphingosine every day because it helps repair the skin barrier and provides anti-inflammatory benefits.

[Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/) [International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/)

### Does phytosphingosine cause purging or irritation?

Phytosphingosine is unlikely to cause purging and helps calm irritation, as it demonstrates natural anti-inflammatory activity.

[International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/)

### Which skin types is phytosphingosine best for?

Phytosphingosine is a good fit for dry, oily, combination, sensitive, acne-prone, mature, and dark-spotted skin types, with Lovi giving top-tier ratings to products like CeraVe PM Facial Moisturizing Lotion and Cetaphil Ceramide [Serum](https://lovi.care/skincare/de/ingredients/serum).

[International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/) [Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/)

### Can you use phytosphingosine with bio-placenta peptides?

Yes, you can use phytosphingosine and [bio-placenta peptides](https://lovi.care/skincare/de/ingredients/bio-placenta-peptides) together in the same routine, applying the phytosphingosine first and following with the bio-placenta peptides.

## Research on phytosphingosine

- [Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/18489348/) Phytosphingosine · International Journal of Cosmetic Science, 2007
- [Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids](https://pubmed.ncbi.nlm.nih.gov/12482041/) Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002
- [Salicyloyl-phytosphingosine: a novel agent for the repair of photoaged skin](https://pubmed.ncbi.nlm.nih.gov/18489360/) Phytosphingosine · International Journal of Cosmetic Science, 2007

## Combining phytosphingosine

- Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/de/ingredients/acetyl-hexapeptide-3-and-phytosphingosine)
- Work well together: [Bio-placenta peptides and phytosphingosine](https://lovi.care/skincare/de/ingredients/bio-placenta-peptides-and-phytosphingosine)
- Work well together: [Collagen peptide and phytosphingosine](https://lovi.care/skincare/de/ingredients/collagen-peptide-and-phytosphingosine)
- Work well together: [Phytosphingosine and copper peptide](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-copper-peptide)
- Work well together: [Hexapeptide and phytosphingosine](https://lovi.care/skincare/de/ingredients/hexapeptide-and-phytosphingosine)
- Work well together: [Phytosphingosine and hexapeptide-9](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-hexapeptide-9)
- Work well together: [Phytosphingosine and palmitoyl pentapeptide-4](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-palmitoyl-pentapeptide-4)
- Work well together: [Phytosphingosine and palmitoyl tripeptide-1](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-palmitoyl-tripeptide-1)
- Work well together: [Phytosphingosine and peptide-rich plasma](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-peptide-rich-plasma)
- Work well together: [Phytosphingosine and triple peptide blend](https://lovi.care/skincare/de/ingredients/phytosphingosine-and-triple-peptide-blend)

## Brands with phytosphingosine

- Korean skincare: [Aestura](https://lovi.care/skincare/de/brands/aestura)
- American skincare: [CeraVe](https://lovi.care/skincare/de/brands/cerave)
- American skincare: [Elizabeth Arden](https://lovi.care/skincare/de/brands/elizabeth-arden)
- French skincare: [Bioderma](https://lovi.care/skincare/de/brands/bioderma)
- American skincare: [Cetaphil](https://lovi.care/skincare/de/brands/cetaphil)
- American skincare: [Obagi](https://lovi.care/skincare/de/brands/obagi)

## Related ingredients

- [Bio-placenta peptides](https://lovi.care/skincare/de/ingredients/bio-placenta-peptides)
- [Hexapeptide](https://lovi.care/skincare/de/ingredients/hexapeptide)
- [Acetyl hexapeptide-3](https://lovi.care/skincare/de/ingredients/acetyl-hexapeptide-3)
- [Collagen peptide](https://lovi.care/skincare/de/ingredients/collagen-peptide)
- [Copper peptide](https://lovi.care/skincare/de/ingredients/copper-peptide)
- [Hexapeptide-9](https://lovi.care/skincare/de/ingredients/hexapeptide-9)
- [Peptide-rich plasma](https://lovi.care/skincare/de/ingredients/peptide-rich-plasma)
- [Triple peptide blend](https://lovi.care/skincare/de/ingredients/triple-peptide-blend)
- [Palmitoyl pentapeptide-4](https://lovi.care/skincare/de/ingredients/palmitoyl-pentapeptide-4)
- [Palmitoyl tripeptide-1](https://lovi.care/skincare/de/ingredients/palmitoyl-tripeptide-1)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every ingredient with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this ingredient guide: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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