# Glycerin and hexapeptide Page: https://lovi.care/skincare/de/ingredients/glycerin-and-hexapeptide The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany. Work well together Use them together by applying your [glycerin](https://lovi.care/skincare/de/ingredients/glycerin) hydrating [serum](https://lovi.care/skincare/de/ingredients/serum) first, followed by your [hexapeptide](https://lovi.care/skincare/de/ingredients/hexapeptide) product, because hydration helps the peptides absorb better. Glycerin draws in moisture to plump your skin, while hexapeptides help smooth the look of fine lines and support firmness. You can adjust your routine by using a gentler hydrating product or waiting a minute between layers if your skin feels sensitive. [Effects of water activity and low molecular weight humectants on skin permeability and hydration dynamics - a double-blind, randomized and controlled study](https://pubmed.ncbi.nlm.nih.gov/24786192/) [The efficiency of humectants as skin moisturizers in the presence of oil](https://pubmed.ncbi.nlm.nih.gov/11301638/) - [All about glycerin](https://lovi.care/skincare/de/ingredients/glycerin) - [All about hexapeptide](https://lovi.care/skincare/de/ingredients/hexapeptide) ### [Glycerin](https://lovi.care/skincare/de/ingredients/glycerin) products - [CeraVe Moisturising Cream](https://lovi.care/skincare/de/p/cerave/moisturising-cream/for/dry-sensitive-skin) — Superior fit — [€16.50 at Amazon](https://www.amazon.de/dp/B07CHPWFXK?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€8.85 at Amazon](https://www.amazon.de/dp/B07C5R51Q9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [Rhode Glazing Milk](https://lovi.care/skincare/de/p/rhode/glazing-milk/for/dry-skin) — Superior fit — [€88.90 at Amazon](https://www.amazon.de/dp/B0HHFDBTB9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [La Roche-Posay Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit - [Cetaphil Gentle Skin Cleanser](https://lovi.care/skincare/de/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [€15.19 at Amazon](https://www.amazon.de/dp/B0GKQNQ5FK?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [€19.75 at Amazon](https://www.amazon.de/dp/B0052EM8L8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [Vanicream Daily Facial Moisturizer](https://lovi.care/skincare/de/p/vanicream/daily-facial-moisturizer/for/dry-skin) — Superior fit - [Neutrogena Hydro Boost Water Gel](https://lovi.care/skincare/de/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [€8.61 at Amazon](https://www.amazon.de/dp/B0849D9GB4?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/de/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [€52.26 at Amazon](https://www.amazon.de/dp/B007M81B4M?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [CeraVe Daily Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/daily-moisturizing-lotion/for/dry-skin) — Superior fit — [€9.75 at Amazon](https://www.amazon.de/dp/B07CG2TD9F?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [Kiehl's Ultra Facial Cream](https://lovi.care/skincare/de/p/kiehl-s/ultra-facial-cream/for/dark-spots) — Average fit — [€23.97 at Amazon](https://www.amazon.de/dp/B004JVSGWU?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/de/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [€38.99 at Amazon](https://www.amazon.de/dp/B0D9C55KBF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) ### [Hexapeptide](https://lovi.care/skincare/de/ingredients/hexapeptide) products - [SkinCeuticals P-TOX](https://lovi.care/skincare/de/p/skinceuticals/p-tox/for/mature-skin) — High fit — [€150.00 at Amazon](https://www.amazon.de/dp/B0FPFJ16KT?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) ## Questions and answers ### Can you use glycerin and hexapeptide together? Yes, [glycerin](https://lovi.care/skincare/de/ingredients/glycerin) and [hexapeptide](https://lovi.care/skincare/de/ingredients/hexapeptide) work well together because combining them enhances hydration and supports peptide delivery. Lovi gives this pairing a High fit rating. ### Which goes first, glycerin or hexapeptide? Glycerin goes first by layering a hydrating [serum](https://lovi.care/skincare/de/ingredients/serum) beneath your peptide product to enhance hydration and peptide delivery. This combination helps support barrier integrity for all skin types, especially dry and mature skin. ### Are glycerin and hexapeptide good for sensitive skin? Glycerin and hexapeptide work well together because combining them enhances hydration and peptide diffusion while supporting barrier integrity for all skin types. This pairing may improve skin comfort and help maintain moisture when used as directed. [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28371204/) ## Research on glycerin and hexapeptide - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Hexapeptide · American Journal of Clinical Dermatology, 2013 - [A randomized, single-blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face](https://pubmed.ncbi.nlm.nih.gov/28371204/) Hexapeptide · Journal of Cosmetic Dermatology, 2017 - [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Hexapeptide · Annals of Dermatology, 2019 ## Other combinations - Work well together: [Salicylic acid and glycerin](https://lovi.care/skincare/de/ingredients/salicylic-acid-and-glycerin) - Keep them apart: [Adapalene and hexapeptide](https://lovi.care/skincare/de/ingredients/adapalene-and-hexapeptide) - Keep them apart: [Hexapeptide and granactive retinoid](https://lovi.care/skincare/de/ingredients/hexapeptide-and-granactive-retinoid) - Keep them apart: [Hexapeptide and hydroxypinacolone retinoate](https://lovi.care/skincare/de/ingredients/hexapeptide-and-hydroxypinacolone-retinoate) - Keep them apart: [Hexapeptide and pro-retinol](https://lovi.care/skincare/de/ingredients/hexapeptide-and-pro-retinol) - Keep them apart: [Hexapeptide and retinal](https://lovi.care/skincare/de/ingredients/hexapeptide-and-retinal) - Keep them apart: [Hexapeptide and retinoid blend](https://lovi.care/skincare/de/ingredients/hexapeptide-and-retinoid-blend) - Depends on the strength: [Retinol and hexapeptide](https://lovi.care/skincare/de/ingredients/retinol-and-hexapeptide) - Keep them apart: [Tretinoin and hexapeptide](https://lovi.care/skincare/de/ingredients/tretinoin-and-hexapeptide) - Keep them apart: [Hexapeptide and vitamin A](https://lovi.care/skincare/de/ingredients/hexapeptide-and-vitamin-a) - Work well together: [Hexapeptide and liposome](https://lovi.care/skincare/de/ingredients/hexapeptide-and-liposome) - Work well together: [Hexapeptide and microcapsule](https://lovi.care/skincare/de/ingredients/hexapeptide-and-microcapsule) - Depends on the strength: [Vitamin C and hexapeptide](https://lovi.care/skincare/de/ingredients/vitamin-c-and-hexapeptide) - Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/de/ingredients/glycerin-and-acetyl-hexapeptide-3) - Work well together: [Glycerin and bio-placenta peptides](https://lovi.care/skincare/de/ingredients/glycerin-and-bio-placenta-peptides) - Work well together: [Glycerin and collagen peptide](https://lovi.care/skincare/de/ingredients/glycerin-and-collagen-peptide) - Work well together: [Glycerin and copper peptide](https://lovi.care/skincare/de/ingredients/glycerin-and-copper-peptide) - Work well together: [Hexapeptide and betaine](https://lovi.care/skincare/de/ingredients/hexapeptide-and-betaine) - Work well together: [Hexapeptide and hyaluronic acid](https://lovi.care/skincare/de/ingredients/hexapeptide-and-hyaluronic-acid) - Work well together: [Glycerin and hexapeptide-9](https://lovi.care/skincare/de/ingredients/glycerin-and-hexapeptide-9) - Work well together: [Glycerin and palmitoyl pentapeptide-4](https://lovi.care/skincare/de/ingredients/glycerin-and-palmitoyl-pentapeptide-4) - Work well together: [Glycerin and palmitoyl tripeptide-1](https://lovi.care/skincare/de/ingredients/glycerin-and-palmitoyl-tripeptide-1) - Work well together: [Glycerin and peptide-rich plasma](https://lovi.care/skincare/de/ingredients/glycerin-and-peptide-rich-plasma) - Work well together: [Glycerin and triple peptide blend](https://lovi.care/skincare/de/ingredients/glycerin-and-triple-peptide-blend) - Work well together: [AHA blend glycolic and citric acids and glycerin](https://lovi.care/skincare/de/ingredients/aha-blend-glycolic-and-citric-acids-and-glycerin) - Work well together: [Glycerin and citric acid](https://lovi.care/skincare/de/ingredients/glycerin-and-citric-acid) - Work well together: [Glycolic acid and glycerin](https://lovi.care/skincare/de/ingredients/glycolic-acid-and-glycerin) - Work well together: [Glycerin and lactic acid](https://lovi.care/skincare/de/ingredients/glycerin-and-lactic-acid) - Work well together: [Glycerin and mandelic acid](https://lovi.care/skincare/de/ingredients/glycerin-and-mandelic-acid) - Depends on the strength: [Niacinamide and hexapeptide](https://lovi.care/skincare/de/ingredients/niacinamide-and-hexapeptide) - Work well together: [Panthenol and hexapeptide](https://lovi.care/skincare/de/ingredients/panthenol-and-hexapeptide) - Work well together: [Glycerin and tri-ceramide complex](https://lovi.care/skincare/de/ingredients/glycerin-and-tri-ceramide-complex) - Work well together: [Bakuchiol and hexapeptide](https://lovi.care/skincare/de/ingredients/bakuchiol-and-hexapeptide) - Work well together: [Hexapeptide and arginine](https://lovi.care/skincare/de/ingredients/hexapeptide-and-arginine) - Work well together: [Hexapeptide and GABA](https://lovi.care/skincare/de/ingredients/hexapeptide-and-gaba) - Work well together: [Hexapeptide and silk amino acids](https://lovi.care/skincare/de/ingredients/hexapeptide-and-silk-amino-acids) - Work well together: [Hexapeptide and taurine](https://lovi.care/skincare/de/ingredients/hexapeptide-and-taurine) - Work well together: [Hexapeptide and theanine](https://lovi.care/skincare/de/ingredients/hexapeptide-and-theanine) - Keep them apart: [AHA blend glycolic and citric acids and hexapeptide](https://lovi.care/skincare/de/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide) - Keep them apart: [Hexapeptide and citric acid](https://lovi.care/skincare/de/ingredients/hexapeptide-and-citric-acid) - Keep them apart: [Glycolic acid and hexapeptide](https://lovi.care/skincare/de/ingredients/glycolic-acid-and-hexapeptide) - Keep them apart: [Hexapeptide and lactic acid](https://lovi.care/skincare/de/ingredients/hexapeptide-and-lactic-acid) - Keep them apart: [Hexapeptide and mandelic acid](https://lovi.care/skincare/de/ingredients/hexapeptide-and-mandelic-acid) - Work well together: [Coenzyme Q10 and hexapeptide](https://lovi.care/skincare/de/ingredients/coenzyme-q10-and-hexapeptide) - Work well together: [Green tea and hexapeptide](https://lovi.care/skincare/de/ingredients/green-tea-and-hexapeptide) - Work well together: [Vitamin E and hexapeptide](https://lovi.care/skincare/de/ingredients/vitamin-e-and-hexapeptide) - Work well together: [Hexapeptide and beta-sitosterol](https://lovi.care/skincare/de/ingredients/hexapeptide-and-beta-sitosterol) - Work well together: [Ceramide-building complex and hexapeptide](https://lovi.care/skincare/de/ingredients/ceramide-building-complex-and-hexapeptide) - Work well together: [Hexapeptide and cholesterol](https://lovi.care/skincare/de/ingredients/hexapeptide-and-cholesterol) - Work well together: [Hexapeptide and phytosphingosine](https://lovi.care/skincare/de/ingredients/hexapeptide-and-phytosphingosine) - Work well together: [Hexapeptide and phytosterol](https://lovi.care/skincare/de/ingredients/hexapeptide-and-phytosterol) - Work well together: [Hexapeptide and squalene](https://lovi.care/skincare/de/ingredients/hexapeptide-and-squalene) - Work well together: [Hexapeptide and tri-ceramide complex](https://lovi.care/skincare/de/ingredients/hexapeptide-and-tri-ceramide-complex) - Keep them apart: [Salicylic acid and hexapeptide](https://lovi.care/skincare/de/ingredients/salicylic-acid-and-hexapeptide) - Keep them apart: [Hexapeptide and baking soda](https://lovi.care/skincare/de/ingredients/hexapeptide-and-baking-soda) - Keep them apart: [Hexapeptide and bleach](https://lovi.care/skincare/de/ingredients/hexapeptide-and-bleach) - Keep them apart: [Hexapeptide and potassium hydroxide](https://lovi.care/skincare/de/ingredients/hexapeptide-and-potassium-hydroxide) - Keep them apart: [Hexapeptide and behenyl alcohol](https://lovi.care/skincare/de/ingredients/hexapeptide-and-behenyl-alcohol) - Keep them apart: [Hexapeptide and isopropyl alcohol](https://lovi.care/skincare/de/ingredients/hexapeptide-and-isopropyl-alcohol) - Keep them apart: [Hexapeptide and polyvinyl alcohol](https://lovi.care/skincare/de/ingredients/hexapeptide-and-polyvinyl-alcohol) - Keep them apart: [Hexapeptide and copper](https://lovi.care/skincare/de/ingredients/hexapeptide-and-copper) - Keep them apart: [Hexapeptide and magnesium](https://lovi.care/skincare/de/ingredients/hexapeptide-and-magnesium) - Keep them apart: [Hexapeptide and zinc](https://lovi.care/skincare/de/ingredients/hexapeptide-and-zinc) - Keep them apart: [Hexapeptide and zinc sulfate](https://lovi.care/skincare/de/ingredients/hexapeptide-and-zinc-sulfate) - Keep them apart: [Benzoyl peroxide and hexapeptide](https://lovi.care/skincare/de/ingredients/benzoyl-peroxide-and-hexapeptide) - Keep them apart: [Azelaic acid and hexapeptide](https://lovi.care/skincare/de/ingredients/azelaic-acid-and-hexapeptide) - Keep them apart: [Hexapeptide and protease](https://lovi.care/skincare/de/ingredients/hexapeptide-and-protease) - Keep them apart: [Hexapeptide and superoxide dismutase](https://lovi.care/skincare/de/ingredients/hexapeptide-and-superoxide-dismutase) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/glycerin-and-hexapeptide - United Kingdom: https://lovi.care/skincare/uk/ingredients/glycerin-and-hexapeptide - Ireland: https://lovi.care/skincare/ie/ingredients/glycerin-and-hexapeptide - Germany: https://lovi.care/skincare/de/ingredients/glycerin-and-hexapeptide (this page) - France: https://lovi.care/skincare/fr/ingredients/glycerin-and-hexapeptide - Italy: https://lovi.care/skincare/it/ingredients/glycerin-and-hexapeptide - Netherlands: https://lovi.care/skincare/nl/ingredients/glycerin-and-hexapeptide - Spain: https://lovi.care/skincare/es/ingredients/glycerin-and-hexapeptide - Canada: https://lovi.care/skincare/ca/ingredients/glycerin-and-hexapeptide - Australia: https://lovi.care/skincare/au/ingredients/glycerin-and-hexapeptide - Singapore: https://lovi.care/skincare/sg/ingredients/glycerin-and-hexapeptide - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/glycerin-and-hexapeptide - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/glycerin-and-hexapeptide