# Skinfix vs Natura Bissé

Page: https://lovi.care/skincare/de/compare/skinfix-vs-natura-bisse

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Skinfix and Natura Bissé are distinct skincare brands known for their nourishing moisturizers, scientifically targeted formulas, and advanced treatments. Skinfix suits dry, sensitive skin best through rich, restorative ingredients, while Natura Bissé suits mature, dry, and sensitive skin best with rich nourishing properties. Both brands offer standout products for acne-prone skin, namely the Barrier+ Triple Lipid-Peptide Cream and the Diamond Extreme, respectively. While the Canadian brand and the Spanish brand differ in their founding eras and [proprietary](https://lovi.care/skincare/de/ingredients/proprietary) approaches, each carefully crafted treatment works to restore balance and vitality to the complexion.

Skinfix is a Canadian skincare brand founded in 2014 and owned by Skinfix Inc..

[beautymatter.com](https://beautymatter.com/articles/skinfix-lands-minority-investment-from-stride-consumer-partners) [cosmeticsbusiness.com](https://cosmeticsbusiness.com/skinfix-receives-investment-from-stride-consumer-partners--180630) [pitchbook.com](https://pitchbook.com/profiles/company/64084-06) [tracxn.com](https://tracxn.com/d/companies/skinfix/__rnqx6Hpl126uCbS_SdRXV6LT-3OGmp-eFlZic9k9aZ0)

Natura Bissé is a Spanish skincare brand founded in 1979 and owned by Natura Bissé International, S.A..

[naturabisse.com](https://www.naturabisse.com/int/en/our-story.html) [tracxn.com](https://tracxn.com/d/accelerator-incubator/ushopal/__yjGH7DKhQGNWnINKarEuFce6tilrPzGJv0PnASFLfpg)

This page compares some of the most popular Skinfix and Natura Bissé products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg57049a3461).

### Popular Skinfix vs Natura Bissé products

#### Natura Bissé

- [Diamond Extreme](https://lovi.care/skincare/de/p/natura-bisse/diamond-extreme/for/mature-skin) — Superior fit — [€266.00 at Amazon](https://www.amazon.de/dp/B0BKLRMKZV?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### Skinfix

- [Barrier+ Triple Lipid-Peptide Cream](https://lovi.care/skincare/de/p/skinfix/barrier-triple-lipid-peptide-cream/for/dry-sensitive-skin) — High fit

### Skinfix vs Natura Bissé moisturizers

#### Natura Bissé

- [Diamond Extreme](https://lovi.care/skincare/de/p/natura-bisse/diamond-extreme/for/mature-skin) — Superior fit — [€266.00 at Amazon](https://www.amazon.de/dp/B0BKLRMKZV?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### Skinfix

- [Barrier+ Triple Lipid-Peptide Cream](https://lovi.care/skincare/de/p/skinfix/barrier-triple-lipid-peptide-cream/for/dry-sensitive-skin) — High fit

## Questions and answers

### Skinfix or Natura Bissé: which is better?

For mature skin, Natura Bissé offers Diamond Extreme, which achieves a Superior Lovi fit level. For dry or sensitive skin types, Skinfix products on this page maintain a High Lovi fit level and are fragrance-free.

### What is the difference between Skinfix and Natura Bissé?

Skinfix products on this page have no fragrance, whereas Natura Bisse includes fragrance in Diamond Extreme. For mature skin, Lovi rates Natura Bisse as Superior and Skinfix as High.

### Skinfix or Natura Bissé: which moisturizer is better?

For mature skin, Natura Bissé Diamond Extreme gets a Superior Lovi fit level, whereas Skinfix Barrier+ Triple Lipid-Peptide Cream achieves a High fit. Every product on the Skinfix page lists no fragrance, while the Natura Bissé moisturizer contains fragrance.

### Which is more affordable, Skinfix or Natura Bissé?

The products on this page do not list pricing information, so a comparison of affordability cannot be made between Skinfix and Natura Bissé.

### Which causes fewer breakouts, Skinfix or Natura Bissé?

Skinfix is a better fit for acne-prone skin than Natura Bisse, as the products on this page get an Average fit level for acne-prone skin compared to a Low fit level for Natura Bisse's Diamond Extreme.

### Which brand was founded earlier, Skinfix or Natura Bissé?

Natura Bissé was founded earlier, in 1979 in Spain, whereas Skinfix was founded later, in 2014 in Canada.

### Do Skinfix products contain fragrance?

Skinfix products on this page do not contain any fragrance in their ingredients.

### Which brand is from Spain, Skinfix or Natura Bissé?

Natura Bissé is from Spain, having been founded there in 1979.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Peptide complex · International Journal of Cosmetic Science, 2005
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum leaf extract flower · Genes, 2020
- [Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells](https://pubmed.ncbi.nlm.nih.gov/23093820/) Leontopodium alpinum leaf extract flower · Mediators of Inflammation, 2012
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function](https://pubmed.ncbi.nlm.nih.gov/35409270/) Rosamarinus officinalis leaf extract rosemary leaf extract · International Journal of Molecular Sciences, 2022
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Formulation and evaluation of exotic fat based cosmeceuticals for skin repair](https://pubmed.ncbi.nlm.nih.gov/20046792/) Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- Canadian skincare: [Skinfix](https://lovi.care/skincare/de/brands/skinfix)
- Spanish skincare: [Natura Bissé](https://lovi.care/skincare/de/brands/natura-bisse)

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- [The Ordinary vs Skinfix](https://lovi.care/skincare/de/compare/the-ordinary-vs-skinfix)
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- [CeraVe vs Skinfix](https://lovi.care/skincare/de/compare/cerave-vs-skinfix)
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- [La Roche-Posay vs Skinfix](https://lovi.care/skincare/de/compare/la-roche-posay-vs-skinfix)
- [La Roche-Posay vs Natura Bissé](https://lovi.care/skincare/de/compare/la-roche-posay-vs-natura-bisse)
- [Dr. Althea vs Skinfix](https://lovi.care/skincare/de/compare/dr-althea-vs-skinfix)
- [Dr. Althea vs Natura Bissé](https://lovi.care/skincare/de/compare/dr-althea-vs-natura-bisse)
- [Some By Mi vs Skinfix](https://lovi.care/skincare/de/compare/some-by-mi-vs-skinfix)
- [Some By Mi vs Natura Bissé](https://lovi.care/skincare/de/compare/some-by-mi-vs-natura-bisse)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/skinfix-vs-natura-bisse
- United Kingdom: https://lovi.care/skincare/uk/compare/skinfix-vs-natura-bisse
- Ireland: https://lovi.care/skincare/ie/compare/skinfix-vs-natura-bisse
- Germany: https://lovi.care/skincare/de/compare/skinfix-vs-natura-bisse (this page)
- France: https://lovi.care/skincare/fr/compare/skinfix-vs-natura-bisse
- Italy: https://lovi.care/skincare/it/compare/skinfix-vs-natura-bisse
- Netherlands: https://lovi.care/skincare/nl/compare/skinfix-vs-natura-bisse
- Spain: https://lovi.care/skincare/es/compare/skinfix-vs-natura-bisse
- Canada: https://lovi.care/skincare/ca/compare/skinfix-vs-natura-bisse
- Australia: https://lovi.care/skincare/au/compare/skinfix-vs-natura-bisse
- Singapore: https://lovi.care/skincare/sg/compare/skinfix-vs-natura-bisse
- Saudi Arabia: https://lovi.care/skincare/sa/compare/skinfix-vs-natura-bisse
- United Arab Emirates: https://lovi.care/skincare/ae/compare/skinfix-vs-natura-bisse
