# La Roche-Posay vs Medik8

Page: https://lovi.care/skincare/de/compare/la-roche-posay-vs-medik8

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

La Roche-Posay and Medik8 are established skincare brands offering distinct approaches to daily care. The French brand provides targeted [serums](https://lovi.care/skincare/de/ingredients/serum), nourishing moisturizers, gentle cleansers, and soothing eye products formulated with hydrating [glycerin](https://lovi.care/skincare/de/ingredients/glycerin), [mineral-rich thermal water](https://lovi.care/skincare/de/ingredients/thermal-water), and brightening [niacinamide](https://lovi.care/skincare/de/ingredients/niacinamide), while the British brand features serums, moisturizers, eye products, toners, and more built around [hyaluronic acid](https://lovi.care/skincare/de/ingredients/hyaluronic-acid). Both options suit dry skin, though the first also caters well to mature skin with comforting, moisture-binding properties, and the second fits sensitive skin best. They differ primarily in their core ingredient philosophies and geographical origins, with the former emphasizing barrier-restoring thermal water and the latter focusing on wrinkle-smoothing hyaluronic acid.

La Roche-Posay is a French skincare brand founded in 1975 and owned by L'Oréal S.A. since 1989.

[laroche-posay.com.au](https://www.laroche-posay.com.au/our-commitments/history.html) [fr.wikipedia.org](https://fr.wikipedia.org/wiki/L%27Or%C3%A9al)

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular La Roche-Posay and Medik8 products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg41d9f27fbd).

### Popular La Roche-Posay vs Medik8 products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/de/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [€102.00 at Amazon](https://www.amazon.de/dp/B0DYV9VSDV?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/de/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [€65.00 at Amazon](https://www.amazon.de/dp/B0DWN2WFLJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/de/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [€56.00 at Amazon](https://www.amazon.de/dp/B0DYV7HDTH?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/de/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€54.90 at Notino](https://www.notino.de/medik8/bakuchiol-peptides-serum-gegen-das-altern-und-hautmakel/p-16156037/)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/de/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [€53.00 at Amazon](https://www.amazon.de/dp/B0DWMZF2GT?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Oxy-R Peptides](https://lovi.care/skincare/de/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [€67.90 at Amazon](https://www.amazon.de/dp/B093R4NDJS?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/de/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [€60.00 at Amazon](https://www.amazon.de/dp/B0DVLQVYFT?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Hydr8 B5 Intense](https://lovi.care/skincare/de/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€73.46 at Amazon](https://www.amazon.de/dp/B0DWN2BL3T?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### La Roche-Posay

- [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit
- [Cicaplast Baume B5+](https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-baume-b5/for/sensitive-skin) — Superior fit — [€15.45 at Amazon](https://www.amazon.de/dp/B0BJFLVCZK?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Mela B3 Serum](https://lovi.care/skincare/de/p/la-roche-posay/mela-b3-serum/for/acne-prone-skin) — High fit — [€36.15 at Amazon](https://www.amazon.de/dp/B0CM4B43DZ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Retinol B3 Serum](https://lovi.care/skincare/de/p/la-roche-posay/retinol-b3-serum/for/dark-spots) — Average fit — [€32.99 at Amazon](https://www.amazon.de/dp/B07Z9Y4M3C?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin) — High fit — [€21.89 at Amazon](https://www.amazon.de/dp/B0GS9W926K?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Hyalu B5 Serum](https://lovi.care/skincare/de/p/la-roche-posay/hyalu-b5-serum/for/sensitive-skin) — High fit — [€41.99 at Amazon](https://www.amazon.de/dp/B0F1G1FLGX?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Lipikar AP+M Triple Repair Moisturizing Cream](https://lovi.care/skincare/de/p/la-roche-posay/lipikar-ap-m-triple-repair-moisturizing-cream/for/dry-skin) — High fit — [€24.99 at Amazon](https://www.amazon.de/dp/B0849KTG44?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Anthelios](https://lovi.care/skincare/de/p/la-roche-posay/anthelios/for/dark-spots) — Superior fit — [€17.49 at Amazon](https://www.amazon.de/dp/B09SLF5ZH8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

## People Say

La Roche-Posay

Medik8

- Sensitive Skin Relief and Gentle Formulas Mostly Mentioned Mostly Mentioned “Great retinol for beginners — La Roche-Posay Retinol B3 Serum” “Only cream that doesn't sting — La Roche-Posay Toleriane Dermallergo Eye Cream” “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum”
- Hydration and Moisture Mostly Mentioned Often Mentioned “absorbs instantly — La Roche-Posay Toleriane Double Repair Face Moisturizer” “skin feels plump — La Roche-Posay Hyalu B5 Serum” “Restores moisture — Medik8 Liquid Peptides” “Instantly quenched the skin — Medik8 Hydr8 B5 Intense”
- Skin Texture Improvement Often Mentioned Often Mentioned “smoother skin — Medik8 Surface Radiance Cleanse” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “skin feels baby soft — Medik8 CRYSTAL RETINAL 3” “Skin feels smoother — La Roche-Posay Retinol B3 Serum”
- Brightening and Glow Sometimes Noted Often Mentioned “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “immediate glow — Medik8 Super C Ferulic” “skin looks brighter — La Roche-Posay Mela B3 Serum”
- Pleasant Texture Rarely Noted Often Mentioned “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream” “Absorbs fast — Medik8 Liquid Peptides” “Texture is divine — Medik8 Bakuchiol Peptides” “lightweight and absorbs quickly — La Roche-Posay Mela B3 Serum”
- High Price and Value Concerns Sometimes Noted Often Mentioned “expensive for the size — La Roche-Posay Hyalu B5 Serum” “Too expensive for the size — La Roche-Posay Toleriane Dermallergo Eye Cream” “Tube is tiny for the price — La Roche-Posay Cicaplast Gel B5” “Expensive per bottle — Medik8 Liquid Peptides”
- Packaging and Pump Issues Often Mentioned Sometimes Noted “Glass bottle breaks easily — Medik8 Liquid Peptides” “hard to get last bit — Medik8 CRYSTAL RETINAL 3” “click mechanism tricky — Medik8 Oxy-R Peptides” “pump stops working — La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream”
- Product Pilling and Texture Issues Often Mentioned Rarely Noted “Can feel sticky if over-applied — Medik8 Liquid Peptides” “slightly sticky — Medik8 Total Moisture Daily Facial Cream” “too oily — Medik8 Super C Ferulic” “pills like crazy — La Roche-Posay Toleriane Double Repair Face Moisturizer”
- Stinging and Skin Irritation Sometimes Noted Rarely Noted “stinging sensation — Medik8 Super C Ferulic” “Caused stinging and redness — Medik8 Press & Glow” “swollen eyes — Medik8 Surface Radiance Cleanse” “burns my eyes — La Roche-Posay Anthelios”

### La Roche-Posay vs Medik8 routines for dry skin

#### Medik8-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [€19.75 at Amazon](https://www.amazon.de/dp/B0052EM8L8?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/de/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [€12.59 at Amazon](https://www.amazon.de/dp/B07B65NJLV?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/de/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€73.46 at Amazon](https://www.amazon.de/dp/B0DWN2BL3T?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Australian Gold Botanical Lotion SPF 30](https://lovi.care/skincare/de/p/australian-gold/botanical-lotion-spf-30/for/dry-skin) — Superior fit — [€21.04 at Amazon](https://www.amazon.de/dp/B0DV9RH665?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/de/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€10.97 at Amazon](https://www.amazon.de/dp/B084Q16G8D?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/de/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€54.90 at Notino](https://www.notino.de/medik8/bakuchiol-peptides-serum-gegen-das-altern-und-hautmakel/p-16156037/) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/de/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [€19.00 at Amazon](https://www.amazon.de/dp/B0DJ1D917P?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

#### La Roche-Posay-focused routine

- Cleanser: [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/dry-skin) — Average fit — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/de/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [€12.59 at Amazon](https://www.amazon.de/dp/B07B65NJLV?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Pure Vitamin C Cream](https://lovi.care/skincare/de/p/la-roche-posay/pure-vitamin-c-cream/for/dry-skin) — Superior fit — [€29.95 at Amazon](https://www.amazon.de/dp/B0038COKQ2?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/de/p/la-roche-posay/anthelios/for/dry-skin) — High fit — [€17.49 at Amazon](https://www.amazon.de/dp/B09SLF5ZH8?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Respectissime Waterproof Eye Makeup Remover](https://lovi.care/skincare/de/p/la-roche-posay/respectissime-waterproof-eye-makeup-remover/for/dry-skin) — High fit — [€17.75 at Amazon](https://www.amazon.de/dp/B000V3MGFS?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Cicaplast Baume B5+](https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-baume-b5/for/dry-skin) — High fit — [€15.45 at Amazon](https://www.amazon.de/dp/B0BJFLVCZK?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/de/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [€19.00 at Amazon](https://www.amazon.de/dp/B0DJ1D917P?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 99% fit](https://lovi.care/skincare/de/skin/dry-skin)

### La Roche-Posay vs Medik8 routines for oily skin

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€11.75 at Amazon](https://www.amazon.de/dp/B07C5XD33D?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€16.59 at Amazon](https://www.amazon.de/dp/B08125WDCF?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/de/p/medik8/hydr8-b5-intense/for/oily-skin) — High fit — [€73.46 at Amazon](https://www.amazon.de/dp/B0DWN2BL3T?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/de/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€32.80 at Amazon](https://www.amazon.de/dp/B0CF22FB86?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/de/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [€104.00 at Amazon](https://www.amazon.de/dp/B0DNJRC1L4?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/de/p/medik8/press-and-glow/for/oily-skin) — Average fit — [€83.00 at Amazon](https://www.amazon.de/dp/B0BHX9PXBQ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/de/p/medik8/oxy-r-peptides/for/oily-skin) — High fit — [€67.90 at Amazon](https://www.amazon.de/dp/B093R4NDJS?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/de/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€48.55 at Amazon](https://www.amazon.de/dp/B0D1YJN279?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Dr. Sebagh Deep Exfoliating Mask](https://lovi.care/skincare/de/p/dr-sebagh/deep-exfoliating-mask/for/oily-skin) — Superior fit — [€81.80 at Amazon](https://www.amazon.de/dp/B00ANF1K5Q?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

#### La Roche-Posay-focused routine

- Cleanser: [MELA B3 Facial Gel Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/mela-b3-facial-gel-cleanser/for/oily-skin) — High fit — [€17.65 at Amazon](https://www.amazon.de/dp/B0CZ3YFMWQ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€16.59 at Amazon](https://www.amazon.de/dp/B08125WDCF?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Toleriane Dermallergo Night Cream](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/oily-skin) — High fit — [€25.20 at Amazon](https://www.amazon.de/dp/B0CNGTWLS7?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/de/p/la-roche-posay/anthelios/for/oily-skin) — Superior fit — [€17.49 at Amazon](https://www.amazon.de/dp/B09SLF5ZH8?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Water Ultra](https://lovi.care/skincare/de/p/la-roche-posay/micellar-water-ultra/for/oily-skin) — Average fit — [€17.85 at Amazon](https://www.amazon.de/dp/B005EZSUS0?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/de/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [€16.90 at Amazon](https://www.amazon.de/dp/B0FJ8STLLW?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/oily-skin) — High fit — [€21.89 at Amazon](https://www.amazon.de/dp/B0GS9W926K?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/de/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€48.55 at Amazon](https://www.amazon.de/dp/B0D1YJN279?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Effaclar Mask](https://lovi.care/skincare/de/p/la-roche-posay/effaclar-mask/for/oily-skin) — Average fit — [€12.45 at Amazon](https://www.amazon.de/dp/B00ZY9MCM6?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 96% fit](https://lovi.care/skincare/de/skin/oily-skin)

### La Roche-Posay vs Medik8 routines for combination skin

#### Medik8-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [€39.99 at Amazon](https://www.amazon.de/dp/B0013522FC?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.de/dp/B07P7VZ2J9?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/de/p/medik8/hydr8-b5-intense/for/combination-skin) — High fit — [€73.46 at Amazon](https://www.amazon.de/dp/B0DWN2BL3T?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/de/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [€104.00 at Amazon](https://www.amazon.de/dp/B0DNJRC1L4?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/de/p/medik8/press-and-glow/for/combination-skin) — High fit — [€83.00 at Amazon](https://www.amazon.de/dp/B0BHX9PXBQ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/de/p/medik8/oxy-r-peptides/for/combination-skin) — High fit — [€67.90 at Amazon](https://www.amazon.de/dp/B093R4NDJS?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/de/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€48.55 at Amazon](https://www.amazon.de/dp/B0D1YJN279?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/de/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — [€28.50 at Amazon](https://www.amazon.de/dp/B0DV8YNCC5?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

#### La Roche-Posay-focused routine

- Cleanser: [MELA B3 Facial Gel Cleanser](https://lovi.care/skincare/de/p/la-roche-posay/mela-b3-facial-gel-cleanser/for/combination-skin) — High fit — [€17.65 at Amazon](https://www.amazon.de/dp/B0CZ3YFMWQ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.de/dp/B07P7VZ2J9?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Toleriane Dermallergo Night Cream](https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night-cream/for/combination-skin) — High fit — [€25.20 at Amazon](https://www.amazon.de/dp/B0CNGTWLS7?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/de/p/la-roche-posay/anthelios/for/combination-skin) — Superior fit — [€17.49 at Amazon](https://www.amazon.de/dp/B09SLF5ZH8?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Respectissime Waterproof Eye Makeup Remover](https://lovi.care/skincare/de/p/la-roche-posay/respectissime-waterproof-eye-makeup-remover/for/combination-skin) — Average fit — [€17.75 at Amazon](https://www.amazon.de/dp/B000V3MGFS?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/de/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€16.98 at Amazon](https://www.amazon.de/dp/B09V7Z4TJG?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Cicaplast Baume B5+](https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-baume-b5/for/combination-skin) — Average fit — [€15.45 at Amazon](https://www.amazon.de/dp/B0BJFLVCZK?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/de/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€48.55 at Amazon](https://www.amazon.de/dp/B0D1YJN279?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Effaclar Mask](https://lovi.care/skincare/de/p/la-roche-posay/effaclar-mask/for/combination-skin) — Average fit — [€12.45 at Amazon](https://www.amazon.de/dp/B00ZY9MCM6?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 96% fit](https://lovi.care/skincare/de/skin/combination-skin)

## Questions and answers

### La Roche-Posay or Medik8: which is better?

Both brands perform well, but Medik8 has a superior routine fit for dry, sensitive, mature, and combination skin on this page. La Roche-Posay is founded in France and owned by L'Oréal S.A., while Medik8 is from the United Kingdom and owned by L'Oréal Groupe.

### What is the difference between La Roche-Posay and Medik8?

Medik8 tends to outperform La Roche-Posay in skin texture improvement, brightening, and overall routine fit for dry, combination, sensitive, mature, and dry sensitive skin. Meanwhile, La Roche-Posay products on this page often come in at a lower price point than Medik8 items.

### La Roche-Posay or Medik8 for dry skin?

Medik8 is a superior fit for dry skin, whereas La Roche-Posay has a high fit for this skin type on this page. Topical [hyaluronic acid](https://lovi.care/skincare/de/ingredients/hyaluronic-acid) helps provide deep hydration and improve skin quality for dry skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### La Roche-Posay or Medik8: which cleanser is better?

Both brands offer effective options depending on your specific needs, with La Roche-Posay providing gentle cleansers like Effaclar Medicated Gel Cleanser and Medik8 featuring surface-renewing products like Surface Radiance Cleanse. Reviewers find that Medik8 excels in skin texture improvement and brightening, while La Roche-Posay offers extensive formulas suited for sensitive skin.

### Which is more affordable, La Roche-Posay or Medik8?

La Roche-Posay tends to be more affordable, whereas high price and value concerns are noted for Medik8 on the products on this page.

### How do the fragrance options differ between La Roche-Posay and Medik8 products on this page?

La Roche-Posay offers more variety, with 21 of 35 products on this page listing no fragrance and 14 including fragrance. In contrast, Medik8 has 11 of 12 products on this page listing no fragrance and only one product with fragrance.

### Which brand performs better for brightening and glow according to the review themes?

Medik8 performs better for brightening and glow according to the review themes.

### What are the founding years and corporate parent companies of La Roche-Posay and Medik8?

La Roche-Posay was founded in 1975 in France and has been owned by L'Oréal S.A. since 1989. Medik8 was founded in 2009 in the United Kingdom and is owned by L'Oréal Groupe.

### La Roche-Posay or Medik8 for oily skin?

Both La Roche-Posay and Medik8 offer products on this page with a High fit level for oily skin. Reviewers indicate that La Roche-Posay provides better value, while Medik8 excels in skin texture improvement and brightening.

### La Roche-Posay or Medik8: which moisturizer is better?

Medik8 helps provide deep hydration and plumping with products like Hydr8 B5 Intense, while La Roche-Posay helps soothe and nourish sensitive skin with options like Toleriane Double Repair Face Moisturizer and Cicaplast Baume B5+. Both brands offer high-performing moisturizers, though Medik8 reaches a Superior routine fit for dry skin compared to La Roche-Posay's High level.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### La Roche-Posay or Medik8 for sensitive skin?

Both La Roche-Posay and Medik8 fit sensitive skin well, with Lovi fit levels of High and Superior respectively. Reviewers indicate that both brands provide equal relief and gentle formulas for sensitive skin.

### La Roche-Posay or Medik8 for acne-prone skin?

Both brands are a strong choice for acne-prone skin, as Lovi rates the routine fit for acne-prone skin as High for La Roche-Posay and High for Medik8. Both brands offer products with ingredients that help improve skin texture and manage breakouts.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome](https://pubmed.ncbi.nlm.nih.gov/33526970/) Lactobacillus · International Journal of Medical Sciences, 2021
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Vesicular carriers containing phenylethyl resorcinol for topical delivery system; liposomes, transfersomes and invasomes](https://pubmed.ncbi.nlm.nih.gov/32104421/) Phenylethyl resorcinol · Asian Journal of Pharmaceutical Sciences, 2018
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ethosomes of Phenylethyl Resorcinol as Vesicular Delivery System for Skin Lightening Applications](https://pubmed.ncbi.nlm.nih.gov/28804723/) Phenylethyl resorcinol · BioMed Research International, 2017
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide-3, Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/35384257/) Lactobacillus · Journal of Cosmetic Dermatology, 2022
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene usp retinoid acne treatment, Adapalene · American Journal of Clinical Dermatology, 2018
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Adapalene, Adapalene usp retinoid acne treatment · American Journal of Clinical Dermatology, 2022
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene, Adapalene usp retinoid acne treatment · Archives of Dermatological Research, 2022
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc · Journal of Controlled Release, 2025
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide-3, Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Argilla · Forschende Komplementarmedizin, 2012
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Neurosensine · Journal of the European Academy of Dermatology and Venereology, 2016
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [2-Mercaptonicotinoyl glycine prevents UV-induced skin darkening and delayed tanning in healthy subjects: A randomized controlled clinical study](https://pubmed.ncbi.nlm.nih.gov/38372022/) 2-mercaptonicotinoyl glycine · Journal of Cosmetic Dermatology, 2024
- [A Bayesian network meta-analysis of 14 molecules inhibiting UV daylight-induced pigmentation](https://pubmed.ncbi.nlm.nih.gov/38433524/) 2-mercaptonicotinoyl glycine · Journal of the European Academy of Dermatology and Venereology, 2024
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Capryloyl salicylic acid, Citric acid · Journal of Cosmetic Dermatology, 2021
- [Amino acid complex (AAComplex) benefits in cosmetic products: In vitro and in vivo clinical studies](https://pubmed.ncbi.nlm.nih.gov/34694692/) Complex amino acid · Journal of Cosmetic Dermatology, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2008
- [Comparative benefit of two thermal spring waters after photodynamic therapy procedure](https://pubmed.ncbi.nlm.nih.gov/17348993/) La roche-posay thermal spring water · Journal of Cosmetic Dermatology, 2007
- [Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations](https://pubmed.ncbi.nlm.nih.gov/33561977/) Complex amino acid · International Journal of Molecular Sciences, 2021
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Comprehensive assessment of the efficacy and safety of a clay mask in oily and acne skin](https://pubmed.ncbi.nlm.nih.gov/38009030/) Argilla · Skin Research and Technology, 2023
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [A dermocosmetic formulation containing Vichy volcanic mineralizing water, Vitreoscilla filiformis extract, niacinamide, hyaluronic acid, and vitamin E regenerates and repairs acutely stressed skin](https://pubmed.ncbi.nlm.nih.gov/34979590/) Vitreoscilla ferment · Journal of the European Academy of Dermatology and Venereology, 2022
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- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) 2-mercaptonicotinoyl glycine · Frontiers in Pharmacology, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/22838094/) Micro-exfoliating lha · Cutis, 2012
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water · Journal of the European Academy of Dermatology and Venereology, 2020
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Capryloyl salicylic acid · Journal of Drugs in Dermatology, 2013
- [Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid](https://pubmed.ncbi.nlm.nih.gov/9603669/) Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study](https://pubmed.ncbi.nlm.nih.gov/38553920/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water, La roche-posay prebiotic thermal water, Thermal water · The Medical Journal of Malaysia, 2024
- [Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/36999489/) Micro-exfoliating lha · Journal of Cosmetic Dermatology, 2023
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study](https://pubmed.ncbi.nlm.nih.gov/41487026/) Zinc gluconate · Journal of Cosmetic Dermatology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate, Homosalate · Journal of Drugs in Dermatology, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Effects of an ultraviolet B radiation absorber on photocarcinogenesis in hairless albino mice](https://pubmed.ncbi.nlm.nih.gov/19365102/) Ethylhexyl triazone · Skin Pharmacology and Physiology, 2009
- [In vitro analysis of immunoprotective effects of topical sunscreens](https://pubmed.ncbi.nlm.nih.gov/20693002/) Ethylhexyl triazone · Toxicology in Vitro, 1994
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
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## The brands

- French skincare: [La Roche-Posay](https://lovi.care/skincare/de/brands/la-roche-posay)
- British skincare: [Medik8](https://lovi.care/skincare/de/brands/medik8)

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- [Medicube vs Medik8](https://lovi.care/skincare/de/compare/medicube-vs-medik8)
- [The Ordinary vs La Roche-Posay](https://lovi.care/skincare/de/compare/the-ordinary-vs-la-roche-posay)
- [The Ordinary vs Medik8](https://lovi.care/skincare/de/compare/the-ordinary-vs-medik8)
- [Beauty of Joseon vs La Roche-Posay](https://lovi.care/skincare/de/compare/beauty-of-joseon-vs-la-roche-posay)
- [Beauty of Joseon vs Medik8](https://lovi.care/skincare/de/compare/beauty-of-joseon-vs-medik8)
- [COSRX vs La Roche-Posay](https://lovi.care/skincare/de/compare/cosrx-vs-la-roche-posay)
- [COSRX vs Medik8](https://lovi.care/skincare/de/compare/cosrx-vs-medik8)
- [CeraVe vs La Roche-Posay](https://lovi.care/skincare/de/compare/cerave-vs-la-roche-posay)
- [CeraVe vs Medik8](https://lovi.care/skincare/de/compare/cerave-vs-medik8)
- [La Roche-Posay vs Dr. Althea](https://lovi.care/skincare/de/compare/la-roche-posay-vs-dr-althea)
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- [La Roche-Posay vs Purito](https://lovi.care/skincare/de/compare/la-roche-posay-vs-purito)
- [La Roche-Posay vs Cetaphil](https://lovi.care/skincare/de/compare/la-roche-posay-vs-cetaphil)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/la-roche-posay-vs-medik8
- United Kingdom: https://lovi.care/skincare/uk/compare/la-roche-posay-vs-medik8
- Ireland: https://lovi.care/skincare/ie/compare/la-roche-posay-vs-medik8
- Germany: https://lovi.care/skincare/de/compare/la-roche-posay-vs-medik8 (this page)
- France: https://lovi.care/skincare/fr/compare/la-roche-posay-vs-medik8
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- Netherlands: https://lovi.care/skincare/nl/compare/la-roche-posay-vs-medik8
- Spain: https://lovi.care/skincare/es/compare/la-roche-posay-vs-medik8
- Canada: https://lovi.care/skincare/ca/compare/la-roche-posay-vs-medik8
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- Saudi Arabia: https://lovi.care/skincare/sa/compare/la-roche-posay-vs-medik8
- United Arab Emirates: https://lovi.care/skincare/ae/compare/la-roche-posay-vs-medik8