# A+ vs NEOCUTIS Page: https://lovi.care/skincare/de/compare/a-vs-neocutis The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany. A+ and NEOCUTIS are skincare brands founded in India in 1990 and Switzerland in 2003, respectively. A+ is widely beloved for its gentle moisturizers and thoughtfully calibrated formulas that suit sensitive skin best, while the Swiss brand is known for its refined [serums](https://lovi.care/skincare/de/ingredients/serum) and moisturizers that suit mature, dry, and stressed skin best because of their deeply restorative properties. The Indian brand features the 345 Relief Cream as a standout product for acne-prone skin to reliably support daily moisture balance, whereas the other brand offers the Bio Serum Firm for acne-prone skin and the lumière for skin with dark spots. Both lines differ in their origins and target skin types, with the former focusing on mild composition and the latter providing balanced, gentle care through consistent application to help restore natural radiance. A+ is an Indian skincare brand founded in 1990. [pitchbook.com](https://pitchbook.com/profiles/company/554388-85) NEOCUTIS is a Swiss skincare brand founded in 2003 and owned by Merz Holding GmbH & Co. KG since 2013. [businesswire.com](https://www.businesswire.com/news/home/20260716926041/en/Merz-Completes-Inaugural-%E2%82%AC450-Million-Schuldschein-Loan-Issuance) [gcimagazine.com](https://www.gcimagazine.com/brands-products/skin-care/news/21870673/merz-to-purchase-neocutis) This page compares some of the most popular A+ and NEOCUTIS products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pga794b3a535). ### Popular A+ vs NEOCUTIS products #### NEOCUTIS - [Bio Serum Firm](https://lovi.care/skincare/de/p/neocutis/bio-serum-firm/for/mature-skin) — High fit - [lumière](https://lovi.care/skincare/de/p/neocutis/lumiere/for/dry-skin) — Average fit #### A+ - [345 Relief Cream](https://lovi.care/skincare/de/p/a/345-relief-cream/for/sensitive-skin) — Average fit — [€18.53 at Amazon](https://www.amazon.de/dp/B0FKGJYFC8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) ## Questions and answers ### A+ or NEOCUTIS: which is better? NEOCUTIS stands out as a better choice because Lovi rates Bio [Serum](https://lovi.care/skincare/de/ingredients/serum) Firm with High fit for mature, dry, and sensitive skin, whereas A+ products on this page have only Average or Low fit. ### What is the difference between A+ and NEOCUTIS? NEOCUTIS features products like Bio Serum Firm that achieve a High Lovi fit for mature skin, whereas A+ offers the 345 Relief Cream which has an Average Lovi fit for the same skin type. Every product from both brands on this page lists no fragrance in its ingredients. ### A+ or NEOCUTIS: which moisturizer is better? NEOCUTIS offers lumière, which Lovi rates as an Average fit for dry skin, while A+ offers 345 Relief Cream, which Lovi also rates as an Average fit for dry skin. ### Which is more affordable, A+ or NEOCUTIS? Neither brand is more affordable on this page because pricing details are not available for either A+ or NEOCUTIS. ### Which causes fewer breakouts, A+ or NEOCUTIS? NEOCUTIS Bio Serum Firm has an Average fit for acne-prone skin, while the products on this page by A+ also have an Average fit. ### Which brand has been on the market longer, A+ or NEOCUTIS? A+ has been on the market longer, having been founded in 1990 compared to NEOCUTIS, which was founded in 2003. ### Do any products from A+ or NEOCUTIS contain fragrance? Every product on this page from both A+ and NEOCUTIS lists no fragrance in its ingredients. ### How does the Lovi fit level for dry skin compare between NEOCUTIS Bio Serum Firm and A+ 345 Relief Cream? NEOCUTIS Bio Serum Firm has a High Lovi fit level for dry skin, while A+ 345 Relief Cream has an Average fit level. ## Research behind their key ingredients - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022 - [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002 - [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020 - [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008 - [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021 - [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017 - [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024 - [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023 - [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022 - [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1 acetate, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015 - [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019 - [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024 - [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025 - [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998 - [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025 - [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025 - [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 acetate, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026 - [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1 acetate · International Journal of Cosmetic Science, 2026 ## The brands - Indian skincare: [A+](https://lovi.care/skincare/de/brands/a) - Swiss skincare: [NEOCUTIS](https://lovi.care/skincare/de/brands/neocutis) ## More comparisons - [SKIN1004 vs A+](https://lovi.care/skincare/de/compare/skin1004-vs-a) - [SKIN1004 vs NEOCUTIS](https://lovi.care/skincare/de/compare/skin1004-vs-neocutis) - [Anua vs A+](https://lovi.care/skincare/de/compare/anua-vs-a) - [Anua vs NEOCUTIS](https://lovi.care/skincare/de/compare/anua-vs-neocutis) - [Medicube vs A+](https://lovi.care/skincare/de/compare/medicube-vs-a) - [Medicube vs NEOCUTIS](https://lovi.care/skincare/de/compare/medicube-vs-neocutis) - [The Ordinary vs A+](https://lovi.care/skincare/de/compare/the-ordinary-vs-a) - [The Ordinary vs NEOCUTIS](https://lovi.care/skincare/de/compare/the-ordinary-vs-neocutis) - [Beauty of Joseon vs A+](https://lovi.care/skincare/de/compare/beauty-of-joseon-vs-a) - [Beauty of Joseon vs NEOCUTIS](https://lovi.care/skincare/de/compare/beauty-of-joseon-vs-neocutis) - [COSRX vs A+](https://lovi.care/skincare/de/compare/cosrx-vs-a) - [COSRX vs NEOCUTIS](https://lovi.care/skincare/de/compare/cosrx-vs-neocutis) - [CeraVe vs A+](https://lovi.care/skincare/de/compare/cerave-vs-a) - [CeraVe vs NEOCUTIS](https://lovi.care/skincare/de/compare/cerave-vs-neocutis) - [La Roche-Posay vs A+](https://lovi.care/skincare/de/compare/la-roche-posay-vs-a) - [La Roche-Posay vs NEOCUTIS](https://lovi.care/skincare/de/compare/la-roche-posay-vs-neocutis) - [Dr. Althea vs A+](https://lovi.care/skincare/de/compare/dr-althea-vs-a) - [Dr. Althea vs NEOCUTIS](https://lovi.care/skincare/de/compare/dr-althea-vs-neocutis) - [Some By Mi vs A+](https://lovi.care/skincare/de/compare/some-by-mi-vs-a) - [Some By Mi vs NEOCUTIS](https://lovi.care/skincare/de/compare/some-by-mi-vs-neocutis) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/a-vs-neocutis - United Kingdom: https://lovi.care/skincare/uk/compare/a-vs-neocutis - Ireland: https://lovi.care/skincare/ie/compare/a-vs-neocutis - Germany: https://lovi.care/skincare/de/compare/a-vs-neocutis (this page) - France: https://lovi.care/skincare/fr/compare/a-vs-neocutis - Italy: https://lovi.care/skincare/it/compare/a-vs-neocutis - Netherlands: https://lovi.care/skincare/nl/compare/a-vs-neocutis - Spain: https://lovi.care/skincare/es/compare/a-vs-neocutis - Canada: https://lovi.care/skincare/ca/compare/a-vs-neocutis - Australia: https://lovi.care/skincare/au/compare/a-vs-neocutis - Singapore: https://lovi.care/skincare/sg/compare/a-vs-neocutis - Saudi Arabia: https://lovi.care/skincare/sa/compare/a-vs-neocutis - United Arab Emirates: https://lovi.care/skincare/ae/compare/a-vs-neocutis