# SK-II vs Endocare

Page: https://lovi.care/skincare/compare/sk-ii-vs-endocare

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

SK-II and Endocare are renowned skincare brands offering luxurious moisturizers, potent [serums](https://lovi.care/skincare/ingredients/serum), clarifying toners, and restorative masks. The Japanese brand is anchored by its signature ingredient, pitera, while the Spanish brand relies on advanced scientific formulations to support the skin. SK-II suits dry skin and acne-prone skin best, whereas Endocare suits mature skin and dry skin best. While both nurture the complexion, they differ in their foundational ingredients and specific target concerns.

SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.

[en.wikipedia.org](https://en.wikipedia.org/wiki/SK-II) [discoversk-ii.wixsite.com](https://discoversk-ii.wixsite.com/home/brand-history) [glossy.co](https://www.glossy.co/beauty/despite-strong-results-in-beauty-in-the-first-quarter-pg-will-eliminate-thousands-of-jobs/)

Endocare is a Spanish skincare brand founded in 1996 and owned by Cantabria Labs.

[pitchbook.com](https://pitchbook.com/profiles/company/267212-62) [endocare.com.tw](https://www.endocare.com.tw/)

This page compares some of the most popular SK-II and Endocare products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg19b218bd57).

### Popular SK-II vs Endocare products

#### SK-II

- [Facial Treatment Essence](https://lovi.care/skincare/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [$99.00 at Amazon](https://www.amazon.com/dp/B000H723LU?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Facial Treatment Mask](https://lovi.care/skincare/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [$100.00 at Amazon](https://www.amazon.com/dp/B078MQP5ZF?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Facial Treatment Clear Lotion](https://lovi.care/skincare/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit — [$80.00 at Amazon](https://www.amazon.com/dp/B072C3MCDH?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Skinpower Advanced Cream](https://lovi.care/skincare/p/sk-ii/skinpower-advanced-cream/for/mature-skin) — High fit — [$255.00 at Amazon](https://www.amazon.com/dp/B0GMLY2Z6D?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Genoptics Ultraura Essence](https://lovi.care/skincare/p/sk-ii/genoptics-ultraura-essence/for/acne-prone-skin) — Superior fit — [$265.00 at Amazon](https://www.amazon.com/dp/B0CVR58C7P?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Facial Treatment Cleansing Oil](https://lovi.care/skincare/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [$75.00 at Amazon](https://www.amazon.com/dp/B084M1R6RH?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Genoptics Spot Essence](https://lovi.care/skincare/p/sk-ii/genoptics-spot-essence/for/dark-spots) — Average fit

#### Endocare

- [Tensage Cream](https://lovi.care/skincare/p/endocare/tensage-cream/for/mature-skin) — Average fit

## Questions and answers

### SK-II or Endocare: which is better?

SK-II stands out as the better choice since the products on this page achieve High or Superior Lovi fits across multiple skin types, whereas Endocare offers only Average to Low fits. Furthermore, Pitera helps improve overall skin texture and condition as a key ingredient.

[Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### What is the difference between SK-II and Endocare?

SK-II offers a wide range of products on this page with High to Superior Lovi fit levels for dry, acne-prone, and oily skin, while Endocare features only one product with Average to Low fit levels. Both brands include no fragrance in their products on this page.

[Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### SK-II or Endocare: which moisturizer is better?

SK-II is the better choice for a moisturizer, as the products on this page achieve High fit levels for dry and mature skin, whereas Endocare rates only Average.

### Which is more affordable, SK-II or Endocare?

This page does not compare prices for SK-II and Endocare, so it is not possible to tell which brand is more affordable.

### Which causes fewer breakouts, SK-II or Endocare?

SK-II helps cause fewer breakouts, as the products on this page achieve high to superior Lovi fit levels for acne-prone skin while Endocare only features Tensage Cream with a low fit level for acne-prone skin.

[Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Which brand has been established longer, SK-II or Endocare?

SK-II has been established longer, having been founded in Japan in 1980 compared to Endocare, which was founded in Spain in 1996.

### Do SK-II and Endocare products contain fragrance?

Both SK-II and Endocare products on this page list no fragrance in their ingredients.

### Which brand offers a facial treatment mask on this page?

SK-II offers a facial treatment mask on this page, while Endocare does not list one.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Nicotinamide w, Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, D-pantothenyl alcohol · American Journal of Clinical Dermatology, 2002
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Periodontology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, D-pantothenyl alcohol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) D-pantothenyl alcohol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2021
- [The Effects of Filtrate of the Secretion of the Cryptomphalus Aspersa on Photoaged Skin](https://pubmed.ncbi.nlm.nih.gov/23652894/) Sca · Journal of Drugs in Dermatology, 2013
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide](https://pubmed.ncbi.nlm.nih.gov/19958429/) Undecylenoyl phenylalanine · Journal of Cosmetic Dermatology, 2009
- [The Moisturizing Efficacy of a Proprietary Dermo-Cosmetic Product( CLS02021) Versus Placebo in a 4-week Application Period](https://pubmed.ncbi.nlm.nih.gov/35774045/) Proprietary · Medical Archives, 2022
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2022
- [Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin](https://pubmed.ncbi.nlm.nih.gov/20883290/) Sodium salicylate · Journal of Cosmetic Dermatology, 2010
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, D-pantothenyl alcohol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Safety of a New Cosmeceutical Regimen Based on the Combination of Snail Secretion Filtrate and Snail Egg Extract to Improve Signs of Skin Aging](https://pubmed.ncbi.nlm.nih.gov/32308795/) Sca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin](https://pubmed.ncbi.nlm.nih.gov/41224059/) Xanthan gum · International Journal of Biological Macromolecules, 2025
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Galactomyces ferment filtrate, Pitera essence, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate, Pitera · Journal of Clinical Medicine, 2023
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A randomized placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/35763437/) Snail secretion filtrate sca growth factor technology filtrate · Journal of Cosmetic Dermatology, 2022
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Galactomyces ferment filtrate, Sk-ii pitera concentrate, Galactomyces ferment filtrate pitera ferment filtrate · Skinmed, 2021
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025

## The brands

- Japanese skincare: [SK-II](https://lovi.care/skincare/brands/sk-ii)
- Spanish skincare: [Endocare](https://lovi.care/skincare/brands/endocare)

## More comparisons

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- [SKIN1004 vs Endocare](https://lovi.care/skincare/compare/skin1004-vs-endocare)
- [Anua vs SK-II](https://lovi.care/skincare/compare/anua-vs-sk-ii)
- [Anua vs Endocare](https://lovi.care/skincare/compare/anua-vs-endocare)
- [Medicube vs SK-II](https://lovi.care/skincare/compare/medicube-vs-sk-ii)
- [Medicube vs Endocare](https://lovi.care/skincare/compare/medicube-vs-endocare)
- [The Ordinary vs SK-II](https://lovi.care/skincare/compare/the-ordinary-vs-sk-ii)
- [The Ordinary vs Endocare](https://lovi.care/skincare/compare/the-ordinary-vs-endocare)
- [Beauty of Joseon vs SK-II](https://lovi.care/skincare/compare/beauty-of-joseon-vs-sk-ii)
- [Beauty of Joseon vs Endocare](https://lovi.care/skincare/compare/beauty-of-joseon-vs-endocare)
- [COSRX vs SK-II](https://lovi.care/skincare/compare/cosrx-vs-sk-ii)
- [COSRX vs Endocare](https://lovi.care/skincare/compare/cosrx-vs-endocare)
- [CeraVe vs SK-II](https://lovi.care/skincare/compare/cerave-vs-sk-ii)
- [CeraVe vs Endocare](https://lovi.care/skincare/compare/cerave-vs-endocare)
- [La Roche-Posay vs SK-II](https://lovi.care/skincare/compare/la-roche-posay-vs-sk-ii)
- [La Roche-Posay vs Endocare](https://lovi.care/skincare/compare/la-roche-posay-vs-endocare)
- [Dr. Althea vs SK-II](https://lovi.care/skincare/compare/dr-althea-vs-sk-ii)
- [Dr. Althea vs Endocare](https://lovi.care/skincare/compare/dr-althea-vs-endocare)
- [Some By Mi vs SK-II](https://lovi.care/skincare/compare/some-by-mi-vs-sk-ii)
- [Some By Mi vs Endocare](https://lovi.care/skincare/compare/some-by-mi-vs-endocare)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sk-ii-vs-endocare (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/sk-ii-vs-endocare
- Ireland: https://lovi.care/skincare/ie/compare/sk-ii-vs-endocare
- Germany: https://lovi.care/skincare/de/compare/sk-ii-vs-endocare
- France: https://lovi.care/skincare/fr/compare/sk-ii-vs-endocare
- Italy: https://lovi.care/skincare/it/compare/sk-ii-vs-endocare
- Netherlands: https://lovi.care/skincare/nl/compare/sk-ii-vs-endocare
- Spain: https://lovi.care/skincare/es/compare/sk-ii-vs-endocare
- Canada: https://lovi.care/skincare/ca/compare/sk-ii-vs-endocare
- Australia: https://lovi.care/skincare/au/compare/sk-ii-vs-endocare
- Singapore: https://lovi.care/skincare/sg/compare/sk-ii-vs-endocare
- Saudi Arabia: https://lovi.care/skincare/sa/compare/sk-ii-vs-endocare
- United Arab Emirates: https://lovi.care/skincare/ae/compare/sk-ii-vs-endocare