# Sesderma vs Vasanti

Page: https://lovi.care/skincare/compare/sesderma-vs-vasanti

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Sesderma and Vasanti are established skincare brands from Spain and Canada, respectively. Sesderma is beloved for its advanced [serums](https://lovi.care/skincare/ingredients/serum) and botanical [extracts](https://lovi.care/skincare/ingredients/extract), while the Canadian brand is cherished for its gentle exfoliants and meticulously balanced formulas. The Spanish brand suits sensitive, hyperpigmented, and aging skin types best, whereas the latter suits balanced, combination, and sensitive skin types best. They differ primarily in their specialized formulations, with the Spanish line utilizing active compounds to refine texture and the other delivering reliable results through thoughtful exfoliation.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

Vasanti is a Canadian skincare brand founded in 1999.

[tracxn.com](https://tracxn.com/d/companies/vasanti-cosmetics/__jIiO3xGh6PV5d8sEl-fri-4BT-df5200B5pu4o-iyQk) [vasanticosmetics.com](https://vasanticosmetics.com/blogs/the-vasanti-blog/birth-of-vasanti-cosmetics)

This page compares some of the most popular Sesderma and Vasanti products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgfc92307bed).

### Popular Sesderma vs Vasanti products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [$60.00 at Amazon](https://www.amazon.com/dp/B00987RKWW?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

#### Vasanti

- [Brighten Up! Exfoliator](https://lovi.care/skincare/p/vasanti/brighten-up-exfoliator/for/dry-skin) — High fit

## Questions and answers

### Sesderma or Vasanti: which is better?

Neither brand is universally better, as Sesderma achieves a High Lovi fit for acne-prone skin and skin with dark spots with its Azelac RU [Serum](https://lovi.care/skincare/ingredients/serum), while Vasanti achieves a High Lovi fit specifically for dry skin with its Brighten Up! Exfoliator.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### What is the difference between Sesderma and Vasanti?

Sesderma was founded in Spain in 1989 and is owned by Grupo Sesderma, while Vasanti was founded in Canada in 1999 and is independently owned. On this page, Sesderma's Azelac RU Serum achieves a High fit for acne-prone, dark spots, and combination skin, whereas Vasanti's Brighten Up! Exfoliator achieves a High fit specifically for dry skin.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which is more affordable, Sesderma or Vasanti?

Neither Sesderma nor Vasanti shows pricing information on this page.

### Which causes fewer breakouts, Sesderma or Vasanti?

For acne-prone skin, Lovi gives Sesderma a High fit and Vasanti an Average fit. Both the products on this page include fragrance.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### In which countries were Sesderma and Vasanti founded?

Sesderma was founded in Spain, while Vasanti was founded in Canada.

### Do the products listed for Sesderma and Vasanti contain fragrance?

Yes, both brands include fragrance in the products listed on this page, as the Sesderma Azelac RU Serum and the Vasanti Brighten Up! Exfoliator both contain fragrance.

### What specific skin types does the Azelac RU Serum fit best according to its Lovi fit levels?

Lovi finds that Azelac RU Serum fits acne-prone skin, skin with dark spots, and combination skin with a High level. Its fit is Average for oily skin, oily acne-prone skin, sensitive skin, and mature skin, and Low for dry sensitive skin and dry skin.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres](https://pubmed.ncbi.nlm.nih.gov/25876142/) Papain · Giornale Italiano Di Dermatologia E Venereologia, 2015
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [The evaluation of aluminum oxide crystal microdermabrasion for photodamage](https://pubmed.ncbi.nlm.nih.gov/11737128/) Aluminum oxide · Dermatologic Surgery, 2001
- [Starch- and carboxymethyl cellulose-based films as active beauty masks with papain incorporation](https://pubmed.ncbi.nlm.nih.gov/36652986/) Carica papaya · International Journal of Biological Macromolecules, 2023
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024

## The brands

- Spanish skincare: [Sesderma](https://lovi.care/skincare/brands/sesderma)
- Canadian skincare: [Vasanti](https://lovi.care/skincare/brands/vasanti)

## More comparisons

- [SKIN1004 vs Sesderma](https://lovi.care/skincare/compare/skin1004-vs-sesderma)
- [SKIN1004 vs Vasanti](https://lovi.care/skincare/compare/skin1004-vs-vasanti)
- [Anua vs Sesderma](https://lovi.care/skincare/compare/anua-vs-sesderma)
- [Anua vs Vasanti](https://lovi.care/skincare/compare/anua-vs-vasanti)
- [Medicube vs Sesderma](https://lovi.care/skincare/compare/medicube-vs-sesderma)
- [Medicube vs Vasanti](https://lovi.care/skincare/compare/medicube-vs-vasanti)
- [The Ordinary vs Sesderma](https://lovi.care/skincare/compare/the-ordinary-vs-sesderma)
- [The Ordinary vs Vasanti](https://lovi.care/skincare/compare/the-ordinary-vs-vasanti)
- [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/compare/beauty-of-joseon-vs-sesderma)
- [Beauty of Joseon vs Vasanti](https://lovi.care/skincare/compare/beauty-of-joseon-vs-vasanti)
- [COSRX vs Sesderma](https://lovi.care/skincare/compare/cosrx-vs-sesderma)
- [COSRX vs Vasanti](https://lovi.care/skincare/compare/cosrx-vs-vasanti)
- [CeraVe vs Sesderma](https://lovi.care/skincare/compare/cerave-vs-sesderma)
- [CeraVe vs Vasanti](https://lovi.care/skincare/compare/cerave-vs-vasanti)
- [La Roche-Posay vs Sesderma](https://lovi.care/skincare/compare/la-roche-posay-vs-sesderma)
- [La Roche-Posay vs Vasanti](https://lovi.care/skincare/compare/la-roche-posay-vs-vasanti)
- [Dr. Althea vs Sesderma](https://lovi.care/skincare/compare/dr-althea-vs-sesderma)
- [Dr. Althea vs Vasanti](https://lovi.care/skincare/compare/dr-althea-vs-vasanti)
- [Some By Mi vs Sesderma](https://lovi.care/skincare/compare/some-by-mi-vs-sesderma)
- [Some By Mi vs Vasanti](https://lovi.care/skincare/compare/some-by-mi-vs-vasanti)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sesderma-vs-vasanti (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-vasanti
- Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-vasanti
- Germany: https://lovi.care/skincare/de/compare/sesderma-vs-vasanti
- France: https://lovi.care/skincare/fr/compare/sesderma-vs-vasanti
- Italy: https://lovi.care/skincare/it/compare/sesderma-vs-vasanti
- Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-vasanti
- Spain: https://lovi.care/skincare/es/compare/sesderma-vs-vasanti
- Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-vasanti
- Australia: https://lovi.care/skincare/au/compare/sesderma-vs-vasanti
- Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-vasanti
- Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-vasanti
- United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-vasanti