REN Clean Skincare vs Hanhoo

Questions and answers

Research behind their key ingredients

• The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study

  Melaleuca alternifolia tree oil leaf · Indian Journal of Dermatology, Venereology and Leprology, 2007

• Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations

  Melaleuca alternifolia tree oil leaf, Aloe barbadensis leaf extract · Clinical Pharmacology, 2018

• Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face study

  Melaleuca alternifolia tree oil leaf · Dermatology, 2014

• A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial

  Melaleuca alternifolia tree oil leaf · Archives of Dermatological Research, 2022

• Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris

  Triethyl citrate · The British Journal of Dermatology, 2007

• Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial

  Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022

• Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison

  Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2019

• Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract

  Salix nigra bark extract willow bark extract · Planta Medica, 2019

• An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging

  Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2010

• Tandem repeated irritation in aged skin induces distinct barrier perturbation and cytokine profile in vivo

  Toluene · The British Journal of Dermatology, 2012

• Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study

  Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026

• The tandem repeated irritation test: a new method to assess prevention of irritant combination damage to the skin

  Toluene · Acta Dermato-venereologica, 2002

• Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery

  Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022

• Protection from combination exposure

  Toluene · Current Problems in Dermatology, 2007

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.