# NIVEA vs Sesderma

Page: https://lovi.care/skincare/compare/nivea-vs-sesderma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

NIVEA and Sesderma are trusted European skincare lines known for gentle, effective formulations. The German brand, founded in 1911, is cherished for reliable sunscreens, targeted [serums](https://lovi.care/skincare/ingredients/serum), and nourishing moisturizers featuring hydrating [glycerin](https://lovi.care/skincare/ingredients/glycerin) that best suits oily and sensitive skin. Meanwhile, the Spanish brand, established in 1989, is beloved for advanced serums and meticulously engineered formulas tailored for sensitive, hyperpigmented, and aging skin. While both companies care deeply for delicate barriers, NIVEA relies on glycerin to improve stratum corneum hydration, whereas Sesderma employs botanical [extracts](https://lovi.care/skincare/ingredients/extract) and active compounds to refine texture and promote radiance.

NIVEA is a German skincare brand founded in 1911 and owned by maxingvest GmbH & Co. KGaA since 2004.

[beiersdorf.com](https://www.beiersdorf.com/about-us/our-history/founding-history) [en.wikipedia.org](https://en.wikipedia.org/wiki/Maxingvest_AG)

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

This page compares some of the most popular NIVEA and Sesderma products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgd2fb74ecb8).

### Popular NIVEA vs Sesderma products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [$60.00 at Amazon](https://www.amazon.com/dp/B00987RKWW?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

#### NIVEA

- [Creme](https://lovi.care/skincare/p/nivea/creme/for/dry-skin) — High fit — [$9.90 at Amazon](https://www.amazon.com/dp/B00DEG8N9W?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Soft](https://lovi.care/skincare/p/nivea/soft/for/dry-sensitive-skin) — Average fit — [$10.99 at Amazon](https://www.amazon.com/dp/B0B5YL9MZF?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [MEN](https://lovi.care/skincare/p/nivea/men/for/dark-spots) — Average fit
- [UV Deep Protect & Care Gel](https://lovi.care/skincare/p/nivea/uv-deep-protect-and-care-gel/for/combination-skin) — High fit
- [DERMA SKIN CLEAR](https://lovi.care/skincare/p/nivea/derma-skin-clear/for/acne-prone-skin) — High fit — [$13.40 at Amazon](https://www.amazon.com/dp/B0C17Q9FGS?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Express Hydration](https://lovi.care/skincare/p/nivea/express-hydration/for/dry-sensitive-skin) — Average fit
- [LUMINOUS630 ANTI-DARK SPOT SERUM](https://lovi.care/skincare/p/nivea/luminous630-anti-dark-spot-serum/for/sensitive-skin) — Average fit
- [Protect & Moisture Sun Lotion SPF50+](https://lovi.care/skincare/p/nivea/protect-and-moisture-sun-lotion-spf50/for/combination-skin) — High fit — [$18.90 at Amazon](https://www.amazon.com/dp/B07MTRSZVL?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

## Questions and answers

### NIVEA or Sesderma: which is better?

NIVEA is better suited for most shoppers on this page because it offers a wider range of products, with Lovi fit levels reaching High for oily, sensitive, and acne-prone skin. [Glycerin](https://lovi.care/skincare/ingredients/glycerin) helps provide intense deep hydration across the products on this page.

### What is the difference between NIVEA and Sesderma?

NIVEA is a German brand offering nine different moisturizers, sunscreens, and [serums](https://lovi.care/skincare/ingredients/serum) on this page, while Sesderma is a Spanish brand represented by only one serum called Azelac RU Serum. Glycerin is a key ingredient across the NIVEA products on this page.

### Which is more affordable, NIVEA or Sesderma?

Neither NIVEA nor Sesderma is explicitly rated for affordability by Lovi on this page. Price comparisons are not included in the provided brand facts.

### Which causes fewer breakouts, NIVEA or Sesderma?

NIVEA helps clear blemishes and gets high Lovi fit ratings for acne-prone skin on the products on this page, while Sesderma has an Azelac RU Serum that also fits acne-prone skin well. However, NIVEA reviewers sometimes note that some products may cause breakouts and acne.

### Which brand has been around longer, NIVEA or Sesderma?

NIVEA has been around longer, having been founded in Germany in 1911, whereas Sesderma was founded later in Spain in 1989.

### How many products are listed for Sesderma compared to NIVEA on the page?

Sesderma has only 1 product listed on this page, while NIVEA has 9 products available. This means shoppers have far more options to explore within the NIVEA range compared to Sesderma.

### Do both NIVEA and Sesderma products contain fragrance?

Yes, both NIVEA and Sesderma products contain fragrance on this page, as 6 of the 9 NIVEA products and the single Sesderma product list fragrance.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Effective reduction of post-inflammatory hyperpigmentation with the tyrosinase inhibitor isobutylamido-thiazolyl-resorcinol (Thiamidol)](https://pubmed.ncbi.nlm.nih.gov/33559186/) Isobutylamido thiazolyl resorcinol · International Journal of Cosmetic Science, 2021
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Exotic Vegetable Oils for Cosmetic O/W Nanoemulsions: In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/26927034/) Lanolin alcohol eucerit · Molecules, 2016
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate, Ethylhexyl methoxycinnamate · Archives of Dermatological Research, 2024
- [Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin](https://pubmed.ncbi.nlm.nih.gov/39138602/) Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025

## The brands

- German skincare: [NIVEA](https://lovi.care/skincare/brands/nivea)
- Spanish skincare: [Sesderma](https://lovi.care/skincare/brands/sesderma)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/nivea-vs-sesderma (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/nivea-vs-sesderma
- Ireland: https://lovi.care/skincare/ie/compare/nivea-vs-sesderma
- Germany: https://lovi.care/skincare/de/compare/nivea-vs-sesderma
- France: https://lovi.care/skincare/fr/compare/nivea-vs-sesderma
- Italy: https://lovi.care/skincare/it/compare/nivea-vs-sesderma
- Netherlands: https://lovi.care/skincare/nl/compare/nivea-vs-sesderma
- Spain: https://lovi.care/skincare/es/compare/nivea-vs-sesderma
- Canada: https://lovi.care/skincare/ca/compare/nivea-vs-sesderma
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- Singapore: https://lovi.care/skincare/sg/compare/nivea-vs-sesderma
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