# Menarini vs Mesoestetic

Page: https://lovi.care/skincare/compare/menarini-vs-mesoestetic

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Menarini and Mesoestetic are two respected skincare options offering advanced [serums](https://lovi.care/skincare/ingredients/serum) and thoughtful formulas that deliver reliable care. The first brand suits sensitive, dry, and combination skin best, featuring the A-Ret Gel as its standout solution for acne-prone skin, while the Spanish brand founded in 1984 suits mature, sensitive, and uneven skin best, relying on the Cosmelan 2 for stubborn blemishes. Both options provide gentle yet effective compositions that support a balanced and healthy complexion. They differ primarily in their specific target concerns and ingredient focuses, with each label tailoring its offerings to elevate daily routines with precision.

Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L..

[mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk)

This page compares some of the most popular Menarini and Mesoestetic products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg89a5682739).

### Popular Menarini vs Mesoestetic products

#### Menarini

- [A-Ret Gel](https://lovi.care/skincare/p/menarini/a-ret-gel/for/oily-skin) — High fit

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

### Menarini vs Mesoestetic [serums](https://lovi.care/skincare/ingredients/serum) and treatments

#### Menarini

- [A-Ret Gel](https://lovi.care/skincare/p/menarini/a-ret-gel/for/oily-skin) — High fit

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

## Questions and answers

### Menarini or Mesoestetic: which is better?

Menarini fits oily and acne-prone skin with High Lovi levels through A-Ret Gel, whereas Mesoestetic products on this page only reach Average levels for those skin types with Cosmelan 2. Both brands list no fragrance in the ingredients of their products on this page.

[The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/) [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/)

### What is the difference between Menarini and Mesoestetic?

Menarini's A-Ret Gel is rated High for oily and oily acne-prone skin on Lovi, whereas Mesoestetic's Cosmelan 2 is rated Average for those same skin types. Both brands offer products on this page that list no fragrance in their ingredients.

[The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/)

### Which is more affordable, Menarini or Mesoestetic?

The page facts do not provide pricing information to determine whether Menarini or Mesoestetic is more affordable.

### Which causes fewer breakouts, Menarini or Mesoestetic?

For oily acne-prone skin, Menarini has a High Lovi fit with A-Ret Gel, whereas Mesoestetic has an Average fit with Cosmelan 2. Both brands list no fragrance in the products on this page.

[The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/) [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/)

### How do the founding years of Menarini and Mesoestetic compare?

Menarini was founded in 1886, while Mesoestetic was established later in 1984.

### Do any of the skincare products from Menarini or Mesoestetic contain fragrance?

Every product from both Menarini and Mesoestetic on this page lists no fragrance in its ingredients.

### Which brand has a higher Lovi fit level for oily skin between A-Ret Gel by Menarini and Cosmelan 2 by Mesoestetic?

A-Ret Gel by Menarini has a High Lovi fit level for oily skin, whereas Cosmelan 2 by Mesoestetic has an Average fit level. [Tretinoin](https://lovi.care/skincare/ingredients/tretinoin) helps treat photodamaged skin and acne.

[The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/) [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/)

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid)](https://pubmed.ncbi.nlm.nih.gov/8336752/) Tretinoin · The New England Journal of Medicine, 1993
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne](https://pubmed.ncbi.nlm.nih.gov/32210603/) Tretinoin · Clinical, Cosmetic and Investigational Dermatology, 2020
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Efficacy assessments of tretinoin-loaded nano lipid carriers in acne vulgaris: a double blind, split-face randomized clinical study](https://pubmed.ncbi.nlm.nih.gov/34146120/) Tretinoin · Archives of Dermatological Research, 2022
- [Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/35620028/) Tretinoin · International Journal of Women's Dermatology, 2022
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023

## The brands

- Skincare: [Menarini](https://lovi.care/skincare/brands/menarini)
- Spanish skincare: [Mesoestetic](https://lovi.care/skincare/brands/mesoestetic)

## More comparisons

- [SKIN1004 vs Menarini](https://lovi.care/skincare/compare/skin1004-vs-menarini)
- [SKIN1004 vs Mesoestetic](https://lovi.care/skincare/compare/skin1004-vs-mesoestetic)
- [Anua vs Menarini](https://lovi.care/skincare/compare/anua-vs-menarini)
- [Anua vs Mesoestetic](https://lovi.care/skincare/compare/anua-vs-mesoestetic)
- [Medicube vs Menarini](https://lovi.care/skincare/compare/medicube-vs-menarini)
- [Medicube vs Mesoestetic](https://lovi.care/skincare/compare/medicube-vs-mesoestetic)
- [The Ordinary vs Menarini](https://lovi.care/skincare/compare/the-ordinary-vs-menarini)
- [The Ordinary vs Mesoestetic](https://lovi.care/skincare/compare/the-ordinary-vs-mesoestetic)
- [Beauty of Joseon vs Menarini](https://lovi.care/skincare/compare/beauty-of-joseon-vs-menarini)
- [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/compare/beauty-of-joseon-vs-mesoestetic)
- [COSRX vs Menarini](https://lovi.care/skincare/compare/cosrx-vs-menarini)
- [COSRX vs Mesoestetic](https://lovi.care/skincare/compare/cosrx-vs-mesoestetic)
- [CeraVe vs Menarini](https://lovi.care/skincare/compare/cerave-vs-menarini)
- [CeraVe vs Mesoestetic](https://lovi.care/skincare/compare/cerave-vs-mesoestetic)
- [La Roche-Posay vs Menarini](https://lovi.care/skincare/compare/la-roche-posay-vs-menarini)
- [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/compare/la-roche-posay-vs-mesoestetic)
- [Dr. Althea vs Menarini](https://lovi.care/skincare/compare/dr-althea-vs-menarini)
- [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/compare/dr-althea-vs-mesoestetic)
- [Some By Mi vs Menarini](https://lovi.care/skincare/compare/some-by-mi-vs-menarini)
- [Some By Mi vs Mesoestetic](https://lovi.care/skincare/compare/some-by-mi-vs-mesoestetic)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/menarini-vs-mesoestetic (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/menarini-vs-mesoestetic
- Ireland: https://lovi.care/skincare/ie/compare/menarini-vs-mesoestetic
- Germany: https://lovi.care/skincare/de/compare/menarini-vs-mesoestetic
- France: https://lovi.care/skincare/fr/compare/menarini-vs-mesoestetic
- Italy: https://lovi.care/skincare/it/compare/menarini-vs-mesoestetic
- Netherlands: https://lovi.care/skincare/nl/compare/menarini-vs-mesoestetic
- Spain: https://lovi.care/skincare/es/compare/menarini-vs-mesoestetic
- Canada: https://lovi.care/skincare/ca/compare/menarini-vs-mesoestetic
- Australia: https://lovi.care/skincare/au/compare/menarini-vs-mesoestetic
- Singapore: https://lovi.care/skincare/sg/compare/menarini-vs-mesoestetic
- Saudi Arabia: https://lovi.care/skincare/sa/compare/menarini-vs-mesoestetic
- United Arab Emirates: https://lovi.care/skincare/ae/compare/menarini-vs-mesoestetic