# La Roche-Posay vs Simple

Page: https://lovi.care/skincare/compare/la-roche-posay-vs-simple

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

La Roche-Posay and Simple are trusted skincare brands that offer gentle moisturizers, cleansers, and targeted treatments enriched with ingredients like [glycerin](https://lovi.care/skincare/ingredients/glycerin) and [niacinamide](https://lovi.care/skincare/ingredients/niacinamide). La Roche-Posay is a French brand loved for [serums](https://lovi.care/skincare/ingredients/serum), moisturizers, cleansers, eye products, and more utilizing [thermal water](https://lovi.care/skincare/ingredients/thermal-water), suiting dry skin and mature skin best. Simple is a British brand chosen for moisturizers, makeup removers, cleansers, and toners suiting acne-prone skin and oily skin best. They differ because the former French line relies additionally on thermal water for compromised moisture barriers, whereas the latter British line focuses on balanced formulations with niacinamide and glycerin.

La Roche-Posay is a French skincare brand founded in 1975 and owned by L'Oréal S.A. since 1989.

[laroche-posay.com.au](https://www.laroche-posay.com.au/our-commitments/history.html) [fr.wikipedia.org](https://fr.wikipedia.org/wiki/L%27Or%C3%A9al)

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

This page compares some of the most popular La Roche-Posay and Simple products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgd8ed8a9033).

### Popular La Roche-Posay vs Simple products

#### La Roche-Posay

- [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit — [$24.99 at Amazon](https://www.amazon.com/dp/B01N9SPQHQ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Cicaplast Baume B5+](https://lovi.care/skincare/p/la-roche-posay/cicaplast-baume-b5/for/sensitive-skin) — Superior fit — [$13.69 at Amazon](https://www.amazon.com/dp/B0060OUV5Y?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Mela B3 Serum](https://lovi.care/skincare/p/la-roche-posay/mela-b3-serum/for/acne-prone-skin) — High fit — [$44.99 at Amazon](https://www.amazon.com/dp/B0CM4B43DZ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Retinol B3 Serum](https://lovi.care/skincare/p/la-roche-posay/retinol-b3-serum/for/dark-spots) — Average fit — [$44.99 at Amazon](https://www.amazon.com/dp/B07Z9Y4M3C?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin) — High fit — [$18.99 at Amazon](https://www.amazon.com/dp/B00LO1DNXU?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Hyalu B5 Serum](https://lovi.care/skincare/p/la-roche-posay/hyalu-b5-serum/for/sensitive-skin) — High fit — [$39.99 at Amazon](https://www.amazon.com/dp/B075VX4QVM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Lipikar AP+M Triple Repair Moisturizing Cream](https://lovi.care/skincare/p/la-roche-posay/lipikar-ap-m-triple-repair-moisturizing-cream/for/dry-skin) — High fit — [$20.99 at Amazon](https://www.amazon.com/dp/B003QXZWYW?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Anthelios](https://lovi.care/skincare/p/la-roche-posay/anthelios/for/dark-spots) — Superior fit — [$20.99 at Amazon](https://www.amazon.com/dp/B01A0NT3D6?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

#### Simple

- [Micellar Water](https://lovi.care/skincare/p/simple/micellar-water/for/mature-skin) — Average fit — [$19.50 at Amazon](https://www.amazon.com/dp/B071XCT81N?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit — [$20.00 at Amazon](https://www.amazon.com/dp/B0G4DWBM9V?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Hydrating Light Moisturiser](https://lovi.care/skincare/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [$6.24 at Amazon](https://www.amazon.com/dp/B000LQX6XG?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [$7.90 at Amazon](https://www.amazon.com/dp/B000LQUA6M?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [$6.40 at Amazon](https://www.amazon.com/dp/B000LNHB6M?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit — [$15.64 at Amazon](https://www.amazon.com/dp/B076TBCFWR?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [$6.67 at Amazon](https://www.amazon.com/dp/B076V2D94Y?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

## People Say

La Roche-Posay

Simple

- Sensitive Skin Friendly Mostly Mentioned Mostly Mentioned “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water” “The only cleanser that doesn't turn my face red. — Simple Micellar Water” “no artificial perfume — Simple Hydrating Light Moisturiser” “Great retinol for beginners — La Roche-Posay Retinol B3 Serum”
- Hydration and Moisture Mostly Mentioned Mostly Mentioned “absorbs instantly — La Roche-Posay Toleriane Double Repair Face Moisturizer” “skin feels plump — La Roche-Posay Hyalu B5 Serum” “banished dryness within days — Simple Replenishing Rich Moisturiser” “sinks in instantly — Simple Water Boost Hydrating Gel Cream”
- Affordable Price Point and Value Not noted Often Mentioned “great value for money — Simple Kind to Skin Soothing Facial Toner” “super affordable — Simple Hydrating Light Moisturiser” “Can't beat the price for the quality. — Simple Micellar Water”
- Fragrance-Free and Gentle Formulas Rarely Noted Often Mentioned “Love that it has absolutely no scent. — Simple Micellar Water” “love that it's alcohol-free — Simple Kind to Skin Soothing Facial Toner” “No strong smell — Simple Refreshing Facial Wash” “zero scent — La Roche-Posay Toleriane Double Repair Face Moisturizer”
- Versatile Application and Makeup Compatibility Rarely Noted Sometimes Noted “makeup lays well — Simple Hydrating Light Moisturiser” “works well under foundation — Simple Replenishing Rich Moisturiser” “foundation sits beautifully on top — Simple Water Boost Hydrating Gel Cream” “Great for chapped lips — La Roche-Posay Cicaplast Baume B5+”
- Skin Texture and Clarity Improvement Often Mentioned Not noted “clears acne blemishes — La Roche-Posay Effaclar Medicated Gel Cleanser” “Skin feels smoother — La Roche-Posay Retinol B3 Serum” “Skin feels softer — La Roche-Posay Pure Vitamin C10 Serum”
- Product Pilling and Texture Issues Often Mentioned Rarely Noted “feels like a film — Simple Hydrating Light Moisturiser” “leaves a tacky film — Simple Kind to Skin Soothing Facial Toner” “pills like crazy — La Roche-Posay Toleriane Double Repair Face Moisturizer”
- Packaging and Pump Faults Often Mentioned Rarely Noted “Worried about the snap top bottle leaking when travelling. — Simple Micellar Cleansing Water” “The cap broke off immediately. — Simple Micellar Water” “hard to get last bit out — Simple Replenishing Rich Moisturiser” “pump stops working — La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream”
- Insufficient Moisture Rarely Noted Often Mentioned “skin felt tight later — La Roche-Posay Toleriane Double Repair Face Moisturizer” “Not moisturizing enough for winter — La Roche-Posay Toleriane Dermallergo Eye Cream” “Need a moisturizer on top for dry skin — La Roche-Posay Cicaplast Gel B5” “not moisturizing enough — Simple Hydrating Light Moisturiser”
- Breakouts and Acne Flare-ups Rarely Noted Sometimes Noted “Triggered cystic acne — La Roche-Posay Cicaplast Baume B5+” “clogged my pores — La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream” “Gave me tiny bumps on my forehead. — Simple Micellar Water”

### La Roche-Posay vs Simple routines for dry skin

#### La Roche-Posay-focused routine

- Cleanser: [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/dry-skin) — Average fit — [$24.99 at Amazon](https://www.amazon.com/dp/B01N9SPQHQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [$16.99 at Amazon](https://www.amazon.com/dp/B08Q6WZ6J1?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Pure Vitamin C Cream](https://lovi.care/skincare/p/la-roche-posay/pure-vitamin-c-cream/for/dry-skin) — Superior fit — [$54.97 at Amazon](https://www.amazon.com/dp/B0038COKQ2?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Micellar Water Ultra](https://lovi.care/skincare/p/la-roche-posay/micellar-water-ultra/for/dry-skin) — Average fit — [$14.99 at Amazon](https://www.amazon.com/dp/B005EZSUS0?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Cicaplast Baume B5+](https://lovi.care/skincare/p/la-roche-posay/cicaplast-baume-b5/for/dry-skin) — High fit — [$13.69 at Amazon](https://www.amazon.com/dp/B0060OUV5Y?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09XWPL5VN?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/p/simple/refreshing-facial-wash/for/dry-skin) — Low fit — [$7.90 at Amazon](https://www.amazon.com/dp/B000LQUA6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [$16.99 at Amazon](https://www.amazon.com/dp/B08Q6WZ6J1?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [$6.40 at Amazon](https://www.amazon.com/dp/B000LNHB6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [$15.99 at Amazon](https://www.amazon.com/dp/B0DKJ63Y6B?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/p/simple/micellar-cleansing-water/for/dry-skin) — High fit — [$20.00 at Amazon](https://www.amazon.com/dp/B0G4DWBM9V?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — [$39.00 at Amazon](https://www.amazon.com/dp/B08H4QPM19?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09XWPL5VN?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy La Roche-Posay routine · $147.63 · 88% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B01N9SPQHQ&Quantity.1=1&ASIN.2=B08Q6WZ6J1&Quantity.2=1&ASIN.3=B0038COKQ2&Quantity.3=1&ASIN.4=B005EZSUS0&Quantity.4=1&ASIN.5=B0060OUV5Y&Quantity.5=1&ASIN.6=B09XWPL5VN&Quantity.6=1&AssociateTag=lovi-care-web-routine-20) [Buy Simple routine · $128.28 · 83% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B08Q6WZ6J1&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B0DKJ63Y6B&Quantity.4=1&ASIN.5=B0G4DWBM9V&Quantity.5=1&ASIN.6=B08H4QPM19&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 99% fit](https://lovi.care/skincare/skin/dry-skin)

### La Roche-Posay vs Simple routines for oily skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/p/simple/refreshing-facial-wash/for/oily-skin) — Average fit — [$7.90 at Amazon](https://www.amazon.com/dp/B000LQUA6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [$15.60 at Amazon](https://www.amazon.com/dp/B08125WDCF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/p/simple/replenishing-rich-moisturiser/for/oily-skin) — Average fit — [$6.40 at Amazon](https://www.amazon.com/dp/B000LNHB6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B00F97FHAW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/p/simple/micellar-cleansing-water/for/oily-skin) — High fit — [$20.00 at Amazon](https://www.amazon.com/dp/B0G4DWBM9V?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [$28.42 at Amazon](https://www.amazon.com/dp/B00KH6QX08?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — [$39.00 at Amazon](https://www.amazon.com/dp/B08H4QPM19?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — [$79.00 at Amazon](https://www.amazon.com/dp/B0DQ5XJ5FK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### La Roche-Posay-focused routine

- Cleanser: [MELA B3 Facial Gel Cleanser](https://lovi.care/skincare/p/la-roche-posay/mela-b3-facial-gel-cleanser/for/oily-skin) — High fit — [$20.99 at Amazon](https://www.amazon.com/dp/B0CZ3YFMWQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [$15.60 at Amazon](https://www.amazon.com/dp/B08125WDCF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-skin) — High fit — [$24.99 at Amazon](https://www.amazon.com/dp/B01N9SPQHQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/p/la-roche-posay/anthelios/for/oily-skin) — Superior fit — [$20.99 at Amazon](https://www.amazon.com/dp/B01A0NT3D6?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Water Ultra](https://lovi.care/skincare/p/la-roche-posay/micellar-water-ultra/for/oily-skin) — Average fit — [$14.99 at Amazon](https://www.amazon.com/dp/B005EZSUS0?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [$28.42 at Amazon](https://www.amazon.com/dp/B00KH6QX08?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Effaclar Adapalene Gel 0.1% Acne Treatment](https://lovi.care/skincare/p/la-roche-posay/effaclar-adapalene-gel-0-1-acne-treatment/for/oily-skin) — Superior fit — [$39.99 at Amazon](https://www.amazon.com/dp/B07SQFQFXX?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Effaclar Mask](https://lovi.care/skincare/p/la-roche-posay/effaclar-mask/for/oily-skin) — Average fit — [$21.97 at Amazon](https://www.amazon.com/dp/B06XH1WJNR?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · $280.29 · 88% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B00F97FHAW&Quantity.4=1&ASIN.5=B0G4DWBM9V&Quantity.5=1&ASIN.6=B00KH6QX08&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B0DQ5XJ5FK&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [Buy La Roche-Posay routine · $256.94 · 86% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B0CZ3YFMWQ&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B01N9SPQHQ&Quantity.3=1&ASIN.4=B01A0NT3D6&Quantity.4=1&ASIN.5=B005EZSUS0&Quantity.5=1&ASIN.6=B00KH6QX08&Quantity.6=1&ASIN.7=B07SQFQFXX&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B06XH1WJNR&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 98% fit](https://lovi.care/skincare/skin/oily-skin)

### La Roche-Posay vs Simple routines for combination skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/p/simple/refreshing-facial-wash/for/combination-skin) — Average fit — [$7.90 at Amazon](https://www.amazon.com/dp/B000LQUA6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [$25.60 at Amazon](https://www.amazon.com/dp/B008EPPIQ4?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/p/simple/replenishing-rich-moisturiser/for/combination-skin) — Average fit — [$6.40 at Amazon](https://www.amazon.com/dp/B000LNHB6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B00F97FHAW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/p/simple/micellar-cleansing-water/for/combination-skin) — Average fit — [$20.00 at Amazon](https://www.amazon.com/dp/B0G4DWBM9V?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [$18.90 at Amazon](https://www.amazon.com/dp/B09V7Z4TJG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — [$39.00 at Amazon](https://www.amazon.com/dp/B08H4QPM19?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [$58.00 at Amazon](https://www.amazon.com/dp/B015RRNQCY?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### La Roche-Posay-focused routine

- Cleanser: [MELA B3 Facial Gel Cleanser](https://lovi.care/skincare/p/la-roche-posay/mela-b3-facial-gel-cleanser/for/combination-skin) — High fit — [$20.99 at Amazon](https://www.amazon.com/dp/B0CZ3YFMWQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [$25.60 at Amazon](https://www.amazon.com/dp/B008EPPIQ4?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Toleriane Dermallergo Night Cream](https://lovi.care/skincare/p/la-roche-posay/toleriane-dermallergo-night-cream/for/combination-skin) — High fit — [$31.97 at Amazon](https://www.amazon.com/dp/B01D2SVADM?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/p/la-roche-posay/anthelios/for/combination-skin) — Superior fit — [$20.99 at Amazon](https://www.amazon.com/dp/B01A0NT3D6?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Water Ultra](https://lovi.care/skincare/p/la-roche-posay/micellar-water-ultra/for/combination-skin) — Average fit — [$14.99 at Amazon](https://www.amazon.com/dp/B005EZSUS0?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [$18.90 at Amazon](https://www.amazon.com/dp/B09V7Z4TJG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Effaclar Adapalene Gel 0.1% Acne Treatment](https://lovi.care/skincare/p/la-roche-posay/effaclar-adapalene-gel-0-1-acne-treatment/for/combination-skin) — Superior fit — [$39.99 at Amazon](https://www.amazon.com/dp/B07SQFQFXX?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Effaclar Mask](https://lovi.care/skincare/p/la-roche-posay/effaclar-mask/for/combination-skin) — Average fit — [$21.97 at Amazon](https://www.amazon.com/dp/B06XH1WJNR?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · $259.77 · 87% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B00F97FHAW&Quantity.4=1&ASIN.5=B0G4DWBM9V&Quantity.5=1&ASIN.6=B09V7Z4TJG&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B015RRNQCY&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [Buy La Roche-Posay routine · $264.40 · 86% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B0CZ3YFMWQ&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B01D2SVADM&Quantity.3=1&ASIN.4=B01A0NT3D6&Quantity.4=1&ASIN.5=B005EZSUS0&Quantity.5=1&ASIN.6=B09V7Z4TJG&Quantity.6=1&ASIN.7=B07SQFQFXX&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B06XH1WJNR&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 97% fit](https://lovi.care/skincare/skin/combination-skin)

## Questions and answers

### La Roche-Posay or Simple: which is better?

Both brands are a High fit for all skin types, so neither is globally better than the other. Simple does better on sensitive skin friendliness, affordable price points, and fragrance-free formulas, whereas La Roche-Posay does better on skin texture and clarity improvement.

### What is the difference between La Roche-Posay and Simple?

Simple tends to be better for sensitive skin and affordable value, whereas La Roche-Posay does better for improving skin texture and clarity. Both brands provide a High routine fit across all skin types on this page.

### La Roche-Posay or Simple for dry skin?

Both La Roche-Posay and Simple fit dry skin well, with Lovi giving each brand a High routine fit level. La Roche-Posay offers products on this page that may help with dry skin through ingredients like [hyaluronic acid](https://lovi.care/skincare/ingredients/hyaluronic-acid), which studies show helps improve skin quality.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### La Roche-Posay or Simple: which cleanser is better?

Both La Roche-Posay and Simple offer effective cleansers, but La Roche-Posay provides a wider variety of specialized options tailored to specific skin concerns like acne and dryness. Simple focuses exclusively on gentle, fragrance-free cleansing formulas that are well-suited for sensitive skin types.

### Which is more affordable, La Roche-Posay or Simple?

Simple does better for affordable price point and value compared to La Roche-Posay.

### Between La Roche-Posay and Simple, which brand offers better fragrance-free and gentle formulas?

Simple does better for fragrance-free and gentle formulas, as every product on this page for the brand lists no fragrance. By contrast, La Roche-Posay includes fragrance in 21 of 35 products on this page.

### How do the companies behind La Roche-Posay and Simple differ in their origins and parent corporations?

La Roche-Posay was founded in 1975 in France and has been owned by L'Oréal S.A. since 1989. In comparison, Simple was founded in 1960 in the United Kingdom and is owned by Unilever PLC.

### Which brand performs better for skin texture and clarity improvement according to reviewers?

La Roche-Posay performs better for skin texture and clarity improvement according to reviewers. The products on this page help improve skin texture and clarity, whereas Simple is more noted for benefits like being sensitive-skin friendly.

### La Roche-Posay or Simple for oily skin?

Both La Roche-Posay and Simple fit oily skin at a High routine level. The products on this page from Simple feature fragrance-free formulas, while La Roche-Posay offers targeted options with ingredients like [niacinamide](https://lovi.care/skincare/ingredients/niacinamide) that helps control oil and improve skin texture.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### La Roche-Posay or Simple: which moisturizer is better?

Simple does better for sensitive skin friendly moisturizers, while the products on this page for La Roche-Posay help with lightweight and hydrating moisturizers.

### La Roche-Posay or Simple for sensitive skin?

Both brands are a High fit for sensitive skin, but Simple is rated better for being sensitive-skin friendly. Simple also features no fragrance across the products on this page, whereas La Roche-Posay includes fragrance in some of its formulas.

### La Roche-Posay or Simple for acne-prone skin?

Both brands offer High routine fit for acne-prone skin on the products on this page, but La Roche-Posay does better at skin texture and clarity improvement.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome](https://pubmed.ncbi.nlm.nih.gov/33526970/) Lactobacillus · International Journal of Medical Sciences, 2021
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Vesicular carriers containing phenylethyl resorcinol for topical delivery system; liposomes, transfersomes and invasomes](https://pubmed.ncbi.nlm.nih.gov/32104421/) Phenylethyl resorcinol · Asian Journal of Pharmaceutical Sciences, 2018
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ethosomes of Phenylethyl Resorcinol as Vesicular Delivery System for Skin Lightening Applications](https://pubmed.ncbi.nlm.nih.gov/28804723/) Phenylethyl resorcinol · BioMed Research International, 2017
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide-3, Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/35384257/) Lactobacillus · Journal of Cosmetic Dermatology, 2022
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene usp retinoid acne treatment, Adapalene · American Journal of Clinical Dermatology, 2018
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Adapalene, Adapalene usp retinoid acne treatment · American Journal of Clinical Dermatology, 2022
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene, Adapalene usp retinoid acne treatment · Archives of Dermatological Research, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract, Madecassoside · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc · Journal of Controlled Release, 2025
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide-3, Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Argilla · Forschende Komplementarmedizin, 2012
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Neurosensine · Journal of the European Academy of Dermatology and Venereology, 2016
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Ginkgo biloba extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [2-Mercaptonicotinoyl glycine prevents UV-induced skin darkening and delayed tanning in healthy subjects: A randomized controlled clinical study](https://pubmed.ncbi.nlm.nih.gov/38372022/) 2-mercaptonicotinoyl glycine · Journal of Cosmetic Dermatology, 2024
- [A Bayesian network meta-analysis of 14 molecules inhibiting UV daylight-induced pigmentation](https://pubmed.ncbi.nlm.nih.gov/38433524/) 2-mercaptonicotinoyl glycine · Journal of the European Academy of Dermatology and Venereology, 2024
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Capryloyl salicylic acid, Citric acid · Journal of Cosmetic Dermatology, 2021
- [Amino acid complex (AAComplex) benefits in cosmetic products: In vitro and in vivo clinical studies](https://pubmed.ncbi.nlm.nih.gov/34694692/) Complex amino acid · Journal of Cosmetic Dermatology, 2022
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2008
- [Comparative benefit of two thermal spring waters after photodynamic therapy procedure](https://pubmed.ncbi.nlm.nih.gov/17348993/) La roche-posay thermal spring water · Journal of Cosmetic Dermatology, 2007
- [Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations](https://pubmed.ncbi.nlm.nih.gov/33561977/) Complex amino acid · International Journal of Molecular Sciences, 2021
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Comprehensive assessment of the efficacy and safety of a clay mask in oily and acne skin](https://pubmed.ncbi.nlm.nih.gov/38009030/) Argilla · Skin Research and Technology, 2023
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [A dermocosmetic formulation containing Vichy volcanic mineralizing water, Vitreoscilla filiformis extract, niacinamide, hyaluronic acid, and vitamin E regenerates and repairs acutely stressed skin](https://pubmed.ncbi.nlm.nih.gov/34979590/) Vitreoscilla ferment · Journal of the European Academy of Dermatology and Venereology, 2022
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) 2-mercaptonicotinoyl glycine · Frontiers in Pharmacology, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/22838094/) Micro-exfoliating lha · Cutis, 2012
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water · Journal of the European Academy of Dermatology and Venereology, 2020
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Capryloyl salicylic acid · Journal of Drugs in Dermatology, 2013
- [Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid](https://pubmed.ncbi.nlm.nih.gov/9603669/) Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
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- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
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- [Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/36999489/) Micro-exfoliating lha · Journal of Cosmetic Dermatology, 2023
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## The brands

- French skincare: [La Roche-Posay](https://lovi.care/skincare/brands/la-roche-posay)
- British skincare: [Simple](https://lovi.care/skincare/brands/simple)

## More comparisons

- [SKIN1004 vs La Roche-Posay](https://lovi.care/skincare/compare/skin1004-vs-la-roche-posay)
- [SKIN1004 vs Simple](https://lovi.care/skincare/compare/skin1004-vs-simple)
- [Anua vs La Roche-Posay](https://lovi.care/skincare/compare/anua-vs-la-roche-posay)
- [Anua vs Simple](https://lovi.care/skincare/compare/anua-vs-simple)
- [Medicube vs La Roche-Posay](https://lovi.care/skincare/compare/medicube-vs-la-roche-posay)
- [Medicube vs Simple](https://lovi.care/skincare/compare/medicube-vs-simple)
- [The Ordinary vs La Roche-Posay](https://lovi.care/skincare/compare/the-ordinary-vs-la-roche-posay)
- [The Ordinary vs Simple](https://lovi.care/skincare/compare/the-ordinary-vs-simple)
- [Beauty of Joseon vs La Roche-Posay](https://lovi.care/skincare/compare/beauty-of-joseon-vs-la-roche-posay)
- [Beauty of Joseon vs Simple](https://lovi.care/skincare/compare/beauty-of-joseon-vs-simple)
- [COSRX vs La Roche-Posay](https://lovi.care/skincare/compare/cosrx-vs-la-roche-posay)
- [COSRX vs Simple](https://lovi.care/skincare/compare/cosrx-vs-simple)
- [CeraVe vs La Roche-Posay](https://lovi.care/skincare/compare/cerave-vs-la-roche-posay)
- [CeraVe vs Simple](https://lovi.care/skincare/compare/cerave-vs-simple)
- [La Roche-Posay vs Dr. Althea](https://lovi.care/skincare/compare/la-roche-posay-vs-dr-althea)
- [La Roche-Posay vs Some By Mi](https://lovi.care/skincare/compare/la-roche-posay-vs-some-by-mi)
- [La Roche-Posay vs Torriden](https://lovi.care/skincare/compare/la-roche-posay-vs-torriden)
- [La Roche-Posay vs celimax](https://lovi.care/skincare/compare/la-roche-posay-vs-celimax)
- [La Roche-Posay vs Purito](https://lovi.care/skincare/compare/la-roche-posay-vs-purito)
- [La Roche-Posay vs Cetaphil](https://lovi.care/skincare/compare/la-roche-posay-vs-cetaphil)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/la-roche-posay-vs-simple (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/la-roche-posay-vs-simple
- Ireland: https://lovi.care/skincare/ie/compare/la-roche-posay-vs-simple
- Germany: https://lovi.care/skincare/de/compare/la-roche-posay-vs-simple
- France: https://lovi.care/skincare/fr/compare/la-roche-posay-vs-simple
- Italy: https://lovi.care/skincare/it/compare/la-roche-posay-vs-simple
- Netherlands: https://lovi.care/skincare/nl/compare/la-roche-posay-vs-simple
- Spain: https://lovi.care/skincare/es/compare/la-roche-posay-vs-simple
- Canada: https://lovi.care/skincare/ca/compare/la-roche-posay-vs-simple
- Australia: https://lovi.care/skincare/au/compare/la-roche-posay-vs-simple
- Singapore: https://lovi.care/skincare/sg/compare/la-roche-posay-vs-simple
- Saudi Arabia: https://lovi.care/skincare/sa/compare/la-roche-posay-vs-simple
- United Arab Emirates: https://lovi.care/skincare/ae/compare/la-roche-posay-vs-simple