# Kiehl's vs Medik8

Page: https://lovi.care/skincare/compare/kiehl-s-vs-medik8

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Kiehl's and Medik8 are heritage and contemporary skincare lines celebrated for targeted formulations. Kiehl's offers dependable moisturizers, [serums](https://lovi.care/skincare/ingredients/serum), toners, eye products, and more featuring nourishing [glycerin](https://lovi.care/skincare/ingredients/glycerin) and squalane to suit mature skin and skin with dark spots best, whereas the British brand provides serums, moisturizers, eye products, toners, and more built around [hyaluronic acid](https://lovi.care/skincare/ingredients/hyaluronic-acid) for dry skin and dry sensitive skin. They differ primarily in their active ingredients and founding eras, with both utilizing distinct solutions like the [Calendula](https://lovi.care/skincare/ingredients/calendula) Herbal-Extract Toner, Surface Radiance Cleanse, Oxy-R Peptides, and Total Moisture Daily Facial Cream to address specific concerns.

Kiehl's is an American skincare brand founded in 1851 and owned by L'Oréal S.A. since 2000.

[loreal.com](https://www.loreal.com/en/press-release/group/loral-acquires-kiehls-deal-expands-lorals-role-in-prestige-market/) [en.wikipedia.org](https://en.wikipedia.org/wiki/L%27Or%C3%A9al)

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular Kiehl's and Medik8 products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg90d68f31e6).

### Popular Kiehl's vs Medik8 products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [$95.00 at Amazon](https://www.amazon.com/dp/B0DT1LYVZ6?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [$66.00 at Amazon](https://www.amazon.com/dp/B0BHX7NYJG?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [$78.00 at Amazon](https://www.amazon.com/dp/B0F8P1V9WQ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [$54.00 at Amazon](https://www.amazon.com/dp/B0C3473CYS?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Oxy-R Peptides](https://lovi.care/skincare/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [$67.00 at Amazon](https://www.amazon.com/dp/B0CKCMLNRK?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0D714LX6K?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Hydr8 B5 Intense](https://lovi.care/skincare/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [$72.00 at Amazon](https://www.amazon.com/dp/B0BHX5MJRG?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

#### Kiehl's

- [Ultra Facial Cream](https://lovi.care/skincare/p/kiehl-s/ultra-facial-cream/for/dark-spots) — Average fit — [$39.00 at Amazon](https://www.amazon.com/dp/B004JVSGWU?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Creamy Eye Treatment with Avocado](https://lovi.care/skincare/p/kiehl-s/creamy-eye-treatment-with-avocado/for/dry-skin) — Average fit — [$40.00 at Amazon](https://www.amazon.com/dp/B000S97MAY?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Clearly Corrective™ Dark Spot Solution](https://lovi.care/skincare/p/kiehl-s/clearly-correctivetm-dark-spot-solution/for/oily-skin) — High fit — [$35.00 at Amazon](https://www.amazon.com/dp/B09DGF5MSL?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Rare Earth Deep Pore Cleansing Masque](https://lovi.care/skincare/p/kiehl-s/rare-earth-deep-pore-cleansing-masque/for/oily-skin) — High fit — [$47.00 at Amazon](https://www.amazon.com/dp/B0FGXQRRC7?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Retinol Skin-Renewing Daily Micro-Dose Serum](https://lovi.care/skincare/p/kiehl-s/retinol-skin-renewing-daily-micro-dose-serum/for/mature-skin) — High fit — [$95.00 at Amazon](https://www.amazon.com/dp/B098TSRWLZ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Midnight Recovery Concentrate](https://lovi.care/skincare/p/kiehl-s/midnight-recovery-concentrate/for/dry-sensitive-skin) — High fit — [$139.00 at Amazon](https://www.amazon.com/dp/B00E1HJLEY?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Better Screen UV Serum](https://lovi.care/skincare/p/kiehl-s/better-screen-uv-serum/for/dark-spots) — High fit — [$45.00 at Amazon](https://www.amazon.com/dp/B0CVJ8M4ZQ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Super Multi-Corrective Cream](https://lovi.care/skincare/p/kiehl-s/super-multi-corrective-cream/for/dry-skin) — High fit — [$76.00 at Amazon](https://www.amazon.com/dp/B08KJ5F26D?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

## People Say

Kiehl's

Medik8

- Gentle on Sensitive Skin Often Mentioned Mostly Mentioned “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “experienced zero irritation — Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum”
- Deep Hydration and Moisture Mostly Mentioned Often Mentioned “Keeps skin moisturized for 24+ hours — Kiehl's Ultra Facial Cream” “Feels like a drink of water — Kiehl's Hydro-Plumping Serum Concentrate” “savior for dry patches — Kiehl's Creamy Eye Treatment with Avocado” “Restores moisture — Medik8 Liquid Peptides”
- Improves Skin Barrier and Texture Often Mentioned Often Mentioned “smoother skin — Medik8 Surface Radiance Cleanse” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “skin feels baby soft — Medik8 CRYSTAL RETINAL 3” “leaves skin feeling silky — Kiehl's Powerful-Strength Line-Reducing Concentrate”
- Lightweight and Non-Greasy Texture Often Mentioned Often Mentioned “feels like nothing — Kiehl's Better Screen UV Serum” “absorbs instantly without residue — Kiehl's Ultra Facial Oil-Free Gel Cream” “Absorbs quickly — Kiehl's Ultra Facial Cream” “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream”
- Fades Dark Spots and Brightens Sometimes Noted Often Mentioned “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “pigmentation lightened slightly — Medik8 Oxy-R Peptides” “Acne marks are gone — Kiehl's Clearly Corrective™ Dark Spot Solution”
- No White Cast and Glowing Finish Sometimes Noted Sometimes Noted “works on dark skin — Kiehl's Better Screen UV Serum” “doubles as moisturizer — Kiehl's Better Screen UV Serum” “Leaves skin looking glass-like and radiant — Medik8 Press & Glow” “brightens skin — Medik8 Surface Radiance Cleanse”
- High Price Point and Poor Value Mostly Mentioned Often Mentioned “Expensive per bottle — Medik8 Liquid Peptides” “very expensive for amount — Medik8 CRYSTAL RETINAL 3” “hefty price tag — Medik8 C-Tetra Serum” “pricy daily staple — Kiehl's Ultra Facial Cream”
- Ineffective or Slow Results Sometimes Noted Sometimes Noted “Did absolutely nothing — Kiehl's Clearly Corrective™ Dark Spot Solution” “Takes months to see — Kiehl's Clearly Corrective™ Dark Spot Solution” “Not as effective as retinol — Medik8 Bakuchiol Peptides” “no difference — Medik8 Oxy-R Peptides”
- Greasy or Oily Residue Sometimes Noted Rarely Noted “too oily for my combination skin — Medik8 C-Tetra Serum” “Oily texture unpleasant — Medik8 Bakuchiol Peptides” “too oily — Medik8 Super C Ferulic” “oil slick in summer — Kiehl's Ultra Facial Cream”

### Kiehl's vs Medik8 routines for dry skin

#### Medik8-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [$19.99 at Amazon](https://www.amazon.com/dp/B01N7T7JKJ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [$16.99 at Amazon](https://www.amazon.com/dp/B08Q6WZ6J1?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [$72.00 at Amazon](https://www.amazon.com/dp/B0BHX5MJRG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [$15.99 at Amazon](https://www.amazon.com/dp/B0DKJ63Y6B?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [$21.70 at Amazon](https://www.amazon.com/dp/B084Q16G8D?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/p/medik8/oxy-r-peptides/for/dry-skin) — High fit — [$67.00 at Amazon](https://www.amazon.com/dp/B0CKCMLNRK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09XWPL5VN?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Kiehl's-focused routine

- Cleanser: [Calendula Deep Cleansing Foaming Face Wash](https://lovi.care/skincare/p/kiehl-s/calendula-deep-cleansing-foaming-face-wash/for/dry-skin) — Average fit — [$39.00 at Amazon](https://www.amazon.com/dp/B00O19W9UA?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Ultra Facial Toner](https://lovi.care/skincare/p/kiehl-s/ultra-facial-toner/for/dry-skin) — High fit — [$26.00 at Amazon](https://www.amazon.com/dp/B00BBF8JA6?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydro-Plumping Serum Concentrate](https://lovi.care/skincare/p/kiehl-s/hydro-plumping-serum-concentrate/for/dry-skin) — Superior fit — [$82.00 at Amazon](https://www.amazon.com/dp/B00XDIHDDS?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Better Screen UV Serum](https://lovi.care/skincare/p/kiehl-s/better-screen-uv-serum/for/dry-skin) — Average fit — [$45.00 at Amazon](https://www.amazon.com/dp/B0CVJ8M4ZQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Midnight Recovery Botanical Cleansing Oil](https://lovi.care/skincare/p/kiehl-s/midnight-recovery-botanical-cleansing-oil/for/dry-skin) — High fit — [$38.00 at Amazon](https://www.amazon.com/dp/B01MCWXYGF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Powerful-Strength Line-Reducing Concentrate](https://lovi.care/skincare/p/kiehl-s/powerful-strength-line-reducing-concentrate/for/dry-skin) — Average fit — [$130.00 at Amazon](https://www.amazon.com/dp/B079X3RX47?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09XWPL5VN?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · $235.67 · 96% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B01N7T7JKJ&Quantity.1=1&ASIN.2=B08Q6WZ6J1&Quantity.2=1&ASIN.3=B0BHX5MJRG&Quantity.3=1&ASIN.4=B0DKJ63Y6B&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0CKCMLNRK&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine-20) [Buy Kiehl's routine · $382.00 · 82% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B00O19W9UA&Quantity.1=1&ASIN.2=B00BBF8JA6&Quantity.2=1&ASIN.3=B00XDIHDDS&Quantity.3=1&ASIN.4=B0CVJ8M4ZQ&Quantity.4=1&ASIN.5=B01MCWXYGF&Quantity.5=1&ASIN.6=B079X3RX47&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 99% fit](https://lovi.care/skincare/skin/dry-skin)

### Kiehl's vs Medik8 routines for oily skin

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [$15.97 at Amazon](https://www.amazon.com/dp/B01N1LL62W?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [$15.60 at Amazon](https://www.amazon.com/dp/B08125WDCF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/p/medik8/hydr8-b5-intense/for/oily-skin) — High fit — [$72.00 at Amazon](https://www.amazon.com/dp/B0BHX5MJRG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B00F97FHAW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0DNJKPSB8?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/p/medik8/press-and-glow/for/oily-skin) — Average fit — [$35.00 at Amazon](https://www.amazon.com/dp/B0BHX9PXBQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/p/medik8/oxy-r-peptides/for/oily-skin) — High fit — [$67.00 at Amazon](https://www.amazon.com/dp/B0CKCMLNRK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — [$79.00 at Amazon](https://www.amazon.com/dp/B0DQ5XJ5FK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Kiehl's-focused routine

- Cleanser: [Calendula Deep Cleansing Foaming Face Wash](https://lovi.care/skincare/p/kiehl-s/calendula-deep-cleansing-foaming-face-wash/for/oily-skin) — Superior fit — [$39.00 at Amazon](https://www.amazon.com/dp/B00O19W9UA?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Ultra Facial Toner](https://lovi.care/skincare/p/kiehl-s/ultra-facial-toner/for/oily-skin) — Average fit — [$26.00 at Amazon](https://www.amazon.com/dp/B00BBF8JA6?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Ultra Facial Oil-Free Gel Cream](https://lovi.care/skincare/p/kiehl-s/ultra-facial-oil-free-gel-cream/for/oily-skin) — High fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09TDHGRVG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Ultra Facial Cream](https://lovi.care/skincare/p/kiehl-s/ultra-facial-cream/for/oily-skin) — Low fit — [$39.00 at Amazon](https://www.amazon.com/dp/B004JVSGWU?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Midnight Recovery Botanical Cleansing Oil](https://lovi.care/skincare/p/kiehl-s/midnight-recovery-botanical-cleansing-oil/for/oily-skin) — Average fit — [$38.00 at Amazon](https://www.amazon.com/dp/B01MCWXYGF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [$28.42 at Amazon](https://www.amazon.com/dp/B00KH6QX08?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Clearly Corrective™ Dark Spot Solution](https://lovi.care/skincare/p/kiehl-s/clearly-correctivetm-dark-spot-solution/for/oily-skin) — High fit — [$35.00 at Amazon](https://www.amazon.com/dp/B09DGF5MSL?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Rare Earth Deep Pore Cleansing Masque](https://lovi.care/skincare/p/kiehl-s/rare-earth-deep-pore-cleansing-masque/for/oily-skin) — High fit — [$47.00 at Amazon](https://www.amazon.com/dp/B0FGXQRRC7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · $418.54 · 90% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B01N1LL62W&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B0BHX5MJRG&Quantity.3=1&ASIN.4=B00F97FHAW&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0BHX9PXBQ&Quantity.6=1&ASIN.7=B0CKCMLNRK&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B0DQ5XJ5FK&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [Buy Kiehl's routine · $343.42 · 80% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B00O19W9UA&Quantity.1=1&ASIN.2=B00BBF8JA6&Quantity.2=1&ASIN.3=B09TDHGRVG&Quantity.3=1&ASIN.4=B004JVSGWU&Quantity.4=1&ASIN.5=B01MCWXYGF&Quantity.5=1&ASIN.6=B00KH6QX08&Quantity.6=1&ASIN.7=B09DGF5MSL&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B0FGXQRRC7&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 98% fit](https://lovi.care/skincare/skin/oily-skin)

### Kiehl's vs Medik8 routines for combination skin

#### Medik8-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [$28.08 at Amazon](https://www.amazon.com/dp/B00AU9EBTC?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [$25.60 at Amazon](https://www.amazon.com/dp/B008EPPIQ4?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/p/medik8/hydr8-b5-intense/for/combination-skin) — High fit — [$72.00 at Amazon](https://www.amazon.com/dp/B0BHX5MJRG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B00F97FHAW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0DNJKPSB8?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/p/medik8/press-and-glow/for/combination-skin) — High fit — [$35.00 at Amazon](https://www.amazon.com/dp/B0BHX9PXBQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/p/medik8/oxy-r-peptides/for/combination-skin) — High fit — [$67.00 at Amazon](https://www.amazon.com/dp/B0CKCMLNRK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [$58.00 at Amazon](https://www.amazon.com/dp/B015RRNQCY?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Kiehl's-focused routine

- Cleanser: [Calendula Deep Cleansing Foaming Face Wash](https://lovi.care/skincare/p/kiehl-s/calendula-deep-cleansing-foaming-face-wash/for/combination-skin) — High fit — [$39.00 at Amazon](https://www.amazon.com/dp/B00O19W9UA?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Ultra Facial Toner](https://lovi.care/skincare/p/kiehl-s/ultra-facial-toner/for/combination-skin) — High fit — [$26.00 at Amazon](https://www.amazon.com/dp/B00BBF8JA6?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Ultra Facial Oil-Free Gel Cream](https://lovi.care/skincare/p/kiehl-s/ultra-facial-oil-free-gel-cream/for/combination-skin) — High fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09TDHGRVG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Better Screen UV Serum](https://lovi.care/skincare/p/kiehl-s/better-screen-uv-serum/for/combination-skin) — High fit — [$45.00 at Amazon](https://www.amazon.com/dp/B0CVJ8M4ZQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Midnight Recovery Botanical Cleansing Oil](https://lovi.care/skincare/p/kiehl-s/midnight-recovery-botanical-cleansing-oil/for/combination-skin) — High fit — [$38.00 at Amazon](https://www.amazon.com/dp/B01MCWXYGF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [$18.90 at Amazon](https://www.amazon.com/dp/B09V7Z4TJG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Clearly Corrective™ Dark Spot Solution](https://lovi.care/skincare/p/kiehl-s/clearly-correctivetm-dark-spot-solution/for/combination-skin) — High fit — [$35.00 at Amazon](https://www.amazon.com/dp/B09DGF5MSL?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Rare Earth Deep Pore Cleansing Masque](https://lovi.care/skincare/p/kiehl-s/rare-earth-deep-pore-cleansing-masque/for/combination-skin) — High fit — [$47.00 at Amazon](https://www.amazon.com/dp/B0FGXQRRC7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · $419.65 · 93% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B0BHX5MJRG&Quantity.3=1&ASIN.4=B00F97FHAW&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0BHX9PXBQ&Quantity.6=1&ASIN.7=B0CKCMLNRK&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B015RRNQCY&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [Buy Kiehl's routine · $339.90 · 83% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B00O19W9UA&Quantity.1=1&ASIN.2=B00BBF8JA6&Quantity.2=1&ASIN.3=B09TDHGRVG&Quantity.3=1&ASIN.4=B0CVJ8M4ZQ&Quantity.4=1&ASIN.5=B01MCWXYGF&Quantity.5=1&ASIN.6=B09V7Z4TJG&Quantity.6=1&ASIN.7=B09DGF5MSL&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B0FGXQRRC7&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 97% fit](https://lovi.care/skincare/skin/combination-skin)

## Questions and answers

### Kiehl's or Medik8: which is better?

Medik8 is often rated as superior for sensitive and acne-prone skin on the products on this page, while Kiehl's is frequently noted for deep hydration and lightweight textures. Both brands share high routines for mature skin and dark spots, though Medik8 may be better for a gentle, non-irritating experience.

### What is the difference between Kiehl's and Medik8?

Medik8 is founded in the UK and owned by L'Oréal Groupe, while Kiehl's is founded in the US and owned by L'Oréal S.A. Reviewers note that Medik8 does better on sensitive skin and fading dark spots, whereas Kiehl's is better known for deep hydration and lightweight textures.

### Kiehl's or Medik8 for dry skin?

Medik8 is a superior fit for dry skin on this page, offering targeted products like Hydr8 B5 Intense and Total Moisture Daily Facial Cream. [Hyaluronic acid](https://lovi.care/skincare/ingredients/hyaluronic-acid) helps provide deep hydration and moisture.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Kiehl's or Medik8: which cleanser is better?

Both Kiehl's and Medik8 offer top-tier cleansers, as Lovi rates the routine fit for the products on this page as Superior for oily skin, oily acne-prone skin, and acne-prone skin for both brands. Medik8 stands out for being more gentle on sensitive skin, while Kiehl's provides a lighter, non-greasy texture.

### Which is more affordable, Kiehl's or Medik8?

Medik8 is noted for having a high price point and poor value compared to Kiehl's.

### Between Kiehl's and Medik8, which brand is better for fading dark spots and brightening?

Medik8 does better for fading dark spots and brightening than Kiehl's according to the review themes on this page. Medik8 helps fade dark spots and brighten the skin effectively while remaining gentle.

### How do the fragrance-free options compare between Kiehl's and Medik8 products?

Kiehl's offers 26 fragrance-free products on this page, while Medik8 has 11 fragrance-free options. Both brands provide a wide selection of products that list no fragrance.

### Which brand performs better for improving skin texture according to review themes?

Medik8 performs better for improving skin texture according to review themes. Reviewers mention that Medik8 helps improve skin texture and supports the skin barrier.

### Kiehl's or Medik8 for oily skin?

Medik8 is superior for oily skin, offering better routine fit than Kiehl's. The products on this page help deliver deep hydration while maintaining a lightweight feel.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Kiehl's or Medik8: which moisturizer is better?

Medik8 helps provide superior dry skin and dry sensitive skin hydration on this page, while Kiehl's offers a high fit for dry skin alongside lightweight, non-greasy moisturizers. Hyaluronic acid helps provide deep hydration and plumping for skin quality.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Kiehl's or Medik8 for sensitive skin?

Medik8 provides a superior routine fit for sensitive skin compared to Kiehl's, and reviewers note that Medik8 does better at being gentle on sensitive skin. Medik8's Hydr8 B5 Intense helps provide deep hydration and plumping using hyaluronic acid.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Kiehl's or Medik8 for acne-prone skin?

Medik8 is a better fit for acne-prone skin, as Lovi rates its routine as Superior compared to an Average fit for Kiehl's. Reviewers on this page note that Medik8 offers gentle [serums](https://lovi.care/skincare/ingredients/serum) that may help improve skin texture without causing irritation.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Topical menthol--a human model for cold pain by activation and sensitization of C nociceptors](https://pubmed.ncbi.nlm.nih.gov/14985268/) Peppermint extract · Brain, 2004
- [Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/27213821/) Curcuma longa · Phytotherapy Research, 2016
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf juice · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/16778793/) Squalane · The Journal of Investigative Dermatology, 2006
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Psychophysical study of the effects of topical application of menthol in healthy volunteers](https://pubmed.ncbi.nlm.nih.gov/16527405/) Menthol · Pain, 2006
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin](https://pubmed.ncbi.nlm.nih.gov/28123324/) Panax ginseng root extract · Journal of Ginseng Research, 2017
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling](https://pubmed.ncbi.nlm.nih.gov/16890388/) Panax ginseng root extract · Journal of Ethnopharmacology, 2007
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Myristic acid reduces skin inflammation and nociception](https://pubmed.ncbi.nlm.nih.gov/34811755/) Myristic acid · Journal of Food Biochemistry, 2022
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Calendula extract: effects on mechanical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/21928714/) Calendula officinalis flower · Acta Poloniae Pharmaceutica, 2011
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia](https://pubmed.ncbi.nlm.nih.gov/23963768/) Menthol · European Journal of Pain, 2014
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Natural Arctium lappa fruit extract improves the clinical signs of aging skin](https://pubmed.ncbi.nlm.nih.gov/19146605/) Arctium lappa root extract · Journal of Cosmetic Dermatology, 2008
- [Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil](https://pubmed.ncbi.nlm.nih.gov/31957954/) Avocado oil · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Palmitoyl oligopeptide · Journal of Cosmetic Dermatology, 2015
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [Evaluation of the Antioxidant, Cytoprotective and Antityrosinase Effects of Schisandra chinensis Extracts and Their Applicability in Skin Care Product](https://pubmed.ncbi.nlm.nih.gov/36558009/) Schisandra chinensis fruit extract · Molecules, 2022
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [In vitro and in vivo studies with tetra-hydro-jasmonic acid (LR2412) reveal its potential to correct signs of skin ageing](https://pubmed.ncbi.nlm.nih.gov/23701744/) Jasmonic acid · Journal of the European Academy of Dermatology and Venereology, 2014
- [In vitro and in vivo anti-allergic effects of Arctium lappa L](https://pubmed.ncbi.nlm.nih.gov/18703753/) Arctium lappa root extract · Experimental Biology and Medicine, 2008
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis oil, Oenothera biennis evening primrose oil · Biomaterials Advances, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Capryloyl salicylic acid, Citric acid · Journal of Cosmetic Dermatology, 2021
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging](https://pubmed.ncbi.nlm.nih.gov/30373163/) Schisandra chinensis fruit extract · International Journal of Molecular Sciences, 2018
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Lipo-hydroxy acid · Journal of Cosmetic Dermatology, 2008
- [Damage and recovery of skin barrier function after glycolic acid chemical peeling and crystal microdermabrasion](https://pubmed.ncbi.nlm.nih.gov/15008867/) Alumina · Dermatologic Surgery, 2004
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Preparation, characterization, and application of polysaccharide-based emulsions incorporated with lavender essential oil for skin-friendly cellulosic support](https://pubmed.ncbi.nlm.nih.gov/34547316/) Lavender essential oil · International Journal of Biological Macromolecules, 2021
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry](https://pubmed.ncbi.nlm.nih.gov/16013388/) Myristic acid · Journal of Food Protection, 2005
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [The evaluation of aluminum oxide crystal microdermabrasion for photodamage](https://pubmed.ncbi.nlm.nih.gov/11737128/) Alumina · Dermatologic Surgery, 2001
- [Skin barrier changes induced by aluminum oxide and sodium chloride microdermabrasion](https://pubmed.ncbi.nlm.nih.gov/12030870/) Alumina · Dermatologic Surgery, 2002
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus cucumber fruit extract juice, Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Genotoxicity of micro- and nano-particles of kaolin in human primary dermal keratinocytes and fibroblasts](https://pubmed.ncbi.nlm.nih.gov/32322315/) Kaolin · Genes and Environment, 2020
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study](https://pubmed.ncbi.nlm.nih.gov/19146603/) Jojoba esters · Journal of Cosmetic Dermatology, 2008
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Capryloyl salicylic acid, Lipo-hydroxy acid · Journal of Drugs in Dermatology, 2013
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid](https://pubmed.ncbi.nlm.nih.gov/9603669/) Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998
- [Clinical and histologic changes determine optimal treatment regimens for microdermabrasion](https://pubmed.ncbi.nlm.nih.gov/19753741/) Alumina · The Journal of Dermatological Treatment, 2002
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Activated c, Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octocrylene · Archives of Dermatological Research, 2024
- [Clinical Assessment of a Novel Jasmonate Cosmeceutical, LR2412-Cx, for the Treatment of Skin Aging](https://pubmed.ncbi.nlm.nih.gov/26885790/) Jasmonic acid · Journal of Drugs in Dermatology, 2016
- [An integrated network pharmacology and molecular docking approach to reveal the role of Arctigenin against Cutibacterium acnes-induced skin inflammation by targeting the CYP19A1](https://pubmed.ncbi.nlm.nih.gov/39090783/) Arctium lappa root extract · Chemical Biology & Drug Design, 2024
- [Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/36999489/) Lipo-hydroxy acid · Journal of Cosmetic Dermatology, 2023
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Octisalate, Homosalate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration](https://pubmed.ncbi.nlm.nih.gov/41129958/) Sodium pca · Biomaterials Advances, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Preclinical Safety Evaluation of Dual Drug-Loaded Nanolipidic Carriers of Dissolvable Patches: In-Vitro and In-Vivo Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/41186117/) Tetrahydrodiferuloylmethane · Molecular Pharmaceutics, 2025
- [Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment](https://pubmed.ncbi.nlm.nih.gov/39339231/) Euterpe oleracea fruit extract · Pharmaceutics, 2024

## The brands

- American skincare: [Kiehl's](https://lovi.care/skincare/brands/kiehl-s)
- British skincare: [Medik8](https://lovi.care/skincare/brands/medik8)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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- United Arab Emirates: https://lovi.care/skincare/ae/compare/kiehl-s-vs-medik8
