# ISDIN vs ELIDEL

Page: https://lovi.care/skincare/compare/isdin-vs-elidel

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

ISDIN and ELIDEL are established skincare companies that provide gentle daily support for maintaining a healthy and balanced complexion. The Spanish brand is known for its elegant moisturizers, advanced sunscreens, restorative [serums](https://lovi.care/skincare/ingredients/serum), and targeted eye products, while the Swiss brand is beloved for its gentle moisturizers and soothing formulas. Both brands suit dry skin and sensitive skin best, providing reliable daily maintenance and dependable protection through carefully balanced compositions. They differ in their specific offerings, as the former features standout solutions like Fusion [Water](https://lovi.care/skincare/ingredients/water) for acne-prone skin, Eryfotona Actinica for dark spots, and K-Ox Eyes for mature skin, whereas the latter offers [Pimecrolimus](https://lovi.care/skincare/ingredients/pimecrolimus) for acne-prone skin.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

ELIDEL is a Swiss skincare brand founded in 2001 and owned by Viatris Inc. since 2016.

[myelidel.ca](https://myelidel.ca/en/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Viatris) [investor.mylan.com](https://investor.mylan.com/news-releases/news-release-details/mylan-completes-acquisition-meda) [sec.gov](https://www.sec.gov/Archives/edgar/data/1114448/000104746904022516/a2139722z6-k.htm)

This page compares some of the most popular ISDIN and ELIDEL products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg8f76247816).

### Popular ISDIN vs ELIDEL products

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [$46.00 at Amazon](https://www.amazon.com/dp/B0CV8716J5?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [$38.00 at Amazon](https://www.amazon.com/dp/B0DWXXJ9Q1?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/p/isdin/k-ox-eyes/for/dry-skin) — High fit — [$106.00 at Amazon](https://www.amazon.com/dp/B01BMLQ4JQ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Hyaluronic Concentrate](https://lovi.care/skincare/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [$115.00 at Amazon](https://www.amazon.com/dp/B01BMLQ086?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [$185.00 at Amazon](https://www.amazon.com/dp/B0CC9W3VWR?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

#### ELIDEL

- [Pimecrolimus](https://lovi.care/skincare/p/elidel/pimecrolimus/for/dry-sensitive-skin) — Average fit

## Questions and answers

### ISDIN or ELIDEL: which is better?

ISDIN is the better-fitting choice overall, as the products on this page achieve Superior and High Lovi fit levels across multiple skin types like dry, sensitive, and acne-prone skin, whereas ELIDEL only reaches Average fits. Reviewers also frequently praise ISDIN for its ultralight, makeup-friendly sunscreens.

### What is the difference between ISDIN and ELIDEL?

ISDIN offers a broad selection of products on the page with varying Lovi fit levels across skin types, whereas ELIDEL includes just one fragrance-free moisturizer with average to low fits. ISDIN products on the page are best suited for dry, sensitive, and acne-prone skin.

### ISDIN or ELIDEL: which moisturizer is better?

For moisturizers, the products on this page by ISDIN generally offer better fit levels for dry and sensitive skin than ELIDEL. Hyaluronic Concentrate by ISDIN helps hydrate sensitive skin with a High Lovi fit level, whereas [Pimecrolimus](https://lovi.care/skincare/ingredients/pimecrolimus) by ELIDEL only achieves an Average fit for dry and sensitive skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Which is more affordable, ISDIN or ELIDEL?

ELIDEL has only one product on this page, while ISDIN offers multiple products that reviewers note have a high price point.

### Which causes fewer breakouts, ISDIN or ELIDEL?

ELIDEL's Pimecrolimus moisturizer has a low fit for acne-prone skin on this page, whereas the products on this page from ISDIN feature several options with high fits for acne-prone skin, such as Fusion [Water](https://lovi.care/skincare/ingredients/water) and Flavo-C [Serum](https://lovi.care/skincare/ingredients/serum).

### Between ISDIN and ELIDEL, which brand offers a sunscreen suitable for dry sensitive skin?

Between the two, ISDIN offers sunscreens like Eryfotona Actinica and Fusion Water that have a Superior fit for dry sensitive skin, whereas ELIDEL does not feature any sunscreens on this page.

### How do the fragrance options differ across the product lines of ISDIN and ELIDEL?

When it comes to fragrance, the products on this page for ISDIN include added scent in five out of eight items, whereas every product on this page for ELIDEL lists no fragrance in its ingredients.

### Which brand has products specifically formulated for mature skin, ISDIN or ELIDEL?

ISDIN is the better choice for mature skin because the products on this page, such as Eryfotona Actinica and Fusion Water, achieve a Superior fit level for mature skin, whereas ELIDEL only reaches a Low fit level for mature skin.

## Research behind their key ingredients

- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types](https://pubmed.ncbi.nlm.nih.gov/40978887/) Cetyl alcohol · Cureus, 2025

## The brands

- Spanish skincare: [ISDIN](https://lovi.care/skincare/brands/isdin)
- Swiss skincare: [ELIDEL](https://lovi.care/skincare/brands/elidel)

## More comparisons

- [SKIN1004 vs ISDIN](https://lovi.care/skincare/compare/skin1004-vs-isdin)
- [SKIN1004 vs ELIDEL](https://lovi.care/skincare/compare/skin1004-vs-elidel)
- [Anua vs ISDIN](https://lovi.care/skincare/compare/anua-vs-isdin)
- [Anua vs ELIDEL](https://lovi.care/skincare/compare/anua-vs-elidel)
- [Medicube vs ISDIN](https://lovi.care/skincare/compare/medicube-vs-isdin)
- [Medicube vs ELIDEL](https://lovi.care/skincare/compare/medicube-vs-elidel)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/compare/the-ordinary-vs-isdin)
- [The Ordinary vs ELIDEL](https://lovi.care/skincare/compare/the-ordinary-vs-elidel)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/compare/beauty-of-joseon-vs-isdin)
- [Beauty of Joseon vs ELIDEL](https://lovi.care/skincare/compare/beauty-of-joseon-vs-elidel)
- [COSRX vs ISDIN](https://lovi.care/skincare/compare/cosrx-vs-isdin)
- [COSRX vs ELIDEL](https://lovi.care/skincare/compare/cosrx-vs-elidel)
- [CeraVe vs ISDIN](https://lovi.care/skincare/compare/cerave-vs-isdin)
- [CeraVe vs ELIDEL](https://lovi.care/skincare/compare/cerave-vs-elidel)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/compare/la-roche-posay-vs-isdin)
- [La Roche-Posay vs ELIDEL](https://lovi.care/skincare/compare/la-roche-posay-vs-elidel)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/compare/dr-althea-vs-isdin)
- [Dr. Althea vs ELIDEL](https://lovi.care/skincare/compare/dr-althea-vs-elidel)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/compare/some-by-mi-vs-isdin)
- [Some By Mi vs ELIDEL](https://lovi.care/skincare/compare/some-by-mi-vs-elidel)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/isdin-vs-elidel (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/isdin-vs-elidel
- Ireland: https://lovi.care/skincare/ie/compare/isdin-vs-elidel
- Germany: https://lovi.care/skincare/de/compare/isdin-vs-elidel
- France: https://lovi.care/skincare/fr/compare/isdin-vs-elidel
- Italy: https://lovi.care/skincare/it/compare/isdin-vs-elidel
- Netherlands: https://lovi.care/skincare/nl/compare/isdin-vs-elidel
- Spain: https://lovi.care/skincare/es/compare/isdin-vs-elidel
- Canada: https://lovi.care/skincare/ca/compare/isdin-vs-elidel
- Australia: https://lovi.care/skincare/au/compare/isdin-vs-elidel
- Singapore: https://lovi.care/skincare/sg/compare/isdin-vs-elidel
- Saudi Arabia: https://lovi.care/skincare/sa/compare/isdin-vs-elidel
- United Arab Emirates: https://lovi.care/skincare/ae/compare/isdin-vs-elidel