# Galderma vs Trilogy

Page: https://lovi.care/skincare/compare/galderma-vs-trilogy

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Galderma and Trilogy are distinct skincare lines, with the former offering targeted [serums](https://lovi.care/skincare/ingredients/serum) and the latter known for gentle cleansers and moisturizers. Galderma suits oily and acne-prone skin best, featuring formulas like Epiduo Gel and Benzac AC, while Trilogy fits dry, balanced, and sensitive skin types best through products such as its [Rosehip](https://lovi.care/skincare/ingredients/rosehip-oil) Cream Cleanser and [Vitamin C](https://lovi.care/skincare/ingredients/vitamin-c) Ceramide Night Cream. Both brands differ in their key ingredients and ideal skin types, giving shoppers clear choices based on their individual needs.

Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma)

This page compares some of the most popular Galderma and Trilogy products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg998b5803b7).

### Popular Galderma vs Trilogy products

#### Galderma

- [Epiduo Gel](https://lovi.care/skincare/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit — [$34.97 at Amazon](https://www.amazon.com/dp/B0GSSCQ6J2?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Benzac AC 5](https://lovi.care/skincare/p/galderma/benzac-ac-5/for/oily-acne-prone-skin) — High fit
- [Benzac AC Mild Strength 2.5% Acne Gel](https://lovi.care/skincare/p/galderma/benzac-ac-mild-strength-2-5-acne-gel/for/oily-acne-prone-skin) — High fit

#### Trilogy

- [Rosehip Cream Cleanser](https://lovi.care/skincare/p/trilogy/rosehip-cream-cleanser/for/sensitive-skin) — High fit
- [Line Smoothing Day Cream](https://lovi.care/skincare/p/trilogy/line-smoothing-day-cream/for/dry-skin) — High fit
- [Vitamin C Ceramide Night Cream](https://lovi.care/skincare/p/trilogy/vitamin-c-ceramide-night-cream/for/mature-skin) — High fit

## People Say

Galderma

Trilogy

- Hydrating Formulas and Deep Hydration Not noted Mostly Mentioned “Keeps skin moisturized — Trilogy Vitamin C Ceramide Night Cream” “Leaves skin thoroughly moisturised — Trilogy Line Smoothing Day Cream” “Feels moisturizing — Trilogy Rosehip Cream Cleanser”
- Acne Clearance and Prevention Mostly Mentioned Not noted “cleared up my skin — Galderma Benzac AC Mild Strength 2.5% Acne Gel” “cystic acne gone — Galderma Epiduo Gel” “stops new pimples — Galderma Epiduo Gel”
- Gentle and Sensitive Skin Care Sometimes Noted Mostly Mentioned “Doesn't irritate my sensitive skin — Trilogy Rosehip Cream Cleanser” “Nothing irritated my skin — Trilogy Line Smoothing Day Cream” “didn't burn my face — Galderma Benzac AC Mild Strength 2.5% Acne Gel”
- Creamy and Rich Textures Not noted Mostly Mentioned “Silky cream consistency — Trilogy Rosehip Cream Cleanser” “Luxuriously rich — Trilogy Vitamin C Ceramide Night Cream”
- Severe Dryness and Peeling Mostly Mentioned Not noted “skin flaking off — Galderma Epiduo Gel”
- Intense Burning and Stinging Mostly Mentioned Not noted “face on fire — Galderma Epiduo Gel”
- Initial Purging and Acne Breakouts Mostly Mentioned Not noted “got worse first — Galderma Epiduo Gel”
- Bleaching Fabrics Mostly Mentioned Not noted “bleached my towel — Galderma Benzac AC 5”

## Questions and answers

### Galderma or Trilogy: which is better?

Galderma is better for acne clearance, holding a High Lovi fit for oily and acne-prone skin, whereas Trilogy is better for hydration and sensitive skin care. Reviewers frequently note that Galderma delivers effective acne-clearing [serums](https://lovi.care/skincare/ingredients/serum) while Trilogy provides hydrating and brightening moisturizers.

### What is the difference between Galderma and Trilogy?

Galderma excels at acne clearance and prevention with effective serums, whereas Trilogy is better for hydrating formulas and gentle sensitive skin care. Galderma fits oily and acne-prone skin best, while the products on this page offer rich moisturizers like [vitamin C](https://lovi.care/skincare/ingredients/vitamin-c) creams.

[The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### Which is more affordable, Galderma or Trilogy?

The page facts do not mention the prices of Galderma or Trilogy products, so it is not possible to say which brand is more affordable.

### Which causes fewer breakouts, Galderma or Trilogy?

Galderma performs better for acne clearance and prevention on the products on this page, making it a stronger choice for minimizing breakouts compared to Trilogy. However, reviewers note that Galderma's acne-clearing serums may also cause severe dryness and peeling.

### Which brand has more products containing fragrance, Galderma or Trilogy?

Trilogy has more products containing fragrance, with two out of three products on this page listing fragrance, whereas every Galderma product on this page lists no fragrance.

### How does the Lovi fit level for dry skin compare between Epiduo Gel and Rosehip Cream Cleanser?

Epiduo Gel has a Low Lovi fit level for dry skin, whereas [Rosehip](https://lovi.care/skincare/ingredients/rosehip-oil) Cream Cleanser has a High fit level for dry skin.

### What are the main negative review themes associated with Galderma compared to Trilogy?

Galderma has negative review themes of severe dryness, peeling, irritation, and discomfort. Trilogy has negative review themes of complaints about product performance and formulation.

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide, Benzoyl peroxide 25mg g · The Cochrane Database of Systematic Reviews, 2020
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene · American Journal of Clinical Dermatology, 2018
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene · Archives of Dermatological Research, 2022
- [Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15](https://pubmed.ncbi.nlm.nih.gov/32224894/) Silicon dioxide · Antioxidants, 2020
- [Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection](https://pubmed.ncbi.nlm.nih.gov/32395645/) Silicon dioxide · Heliyon, 2020
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023
- [Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/37367119/) Carbomer 940 · Gels, 2023
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Topical Almond Oil for Prevention of Pressure Injuries: A Single-Blinded Comparison Study](https://pubmed.ncbi.nlm.nih.gov/32379165/) Prunus amygdalus dulcis oil · Journal of Wound, Ostomy, and Continence Nursing, 2020
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Monocentric, Vehicle-Controlled, Double-Blind Study to Assess the Short- and Long-Term Effects of a Ceramide NP C15-Containing Emollient on the Skin Microbiome and the Skin Barrier Function in Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/41758783/) Ceramide iii · Skin Pharmacology and Physiology, 2026

## The brands

- Swiss skincare: [Galderma](https://lovi.care/skincare/brands/galderma)
- Skincare: [Trilogy](https://lovi.care/skincare/brands/trilogy)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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