# Galderma vs ISDIN Isdinceutics

Page: https://lovi.care/skincare/compare/galderma-vs-isdin-isdinceutics

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Galderma and ISDIN Isdinceutics are two established international skincare houses offering specialized [serums](https://lovi.care/skincare/ingredients/serum), eye treatments, and targeted formulations. The Swiss brand, founded in 1981, is recognized for its acne and spot treatments, featuring key ingredients that best suit oily and acne-prone skin through products like Epiduo Gel and Benzac AC. Meanwhile, the Spanish brand, founded in 1975, is revered for its gentle yet effective advanced formulas, which suit mature, dry, and sensitive skin best with standout options like K-Ox Eyes. They differ primarily in their core focuses, with the former centering on blemish management and the latter emphasizing rested, smooth, and balanced complexions.

Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma)

ISDIN Isdinceutics is a Spanish skincare brand founded in 1975 and owned by Puig since 2027.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/)

This page compares some of the most popular Galderma and ISDIN Isdinceutics products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgfe2be2c050).

### Popular Galderma vs ISDIN Isdinceutics products

#### Galderma

- [Epiduo Gel](https://lovi.care/skincare/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit — [$34.97 at Amazon](https://www.amazon.com/dp/B0GSSCQ6J2?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Benzac AC 5](https://lovi.care/skincare/p/galderma/benzac-ac-5/for/oily-acne-prone-skin) — High fit
- [Benzac AC Mild Strength 2.5% Acne Gel](https://lovi.care/skincare/p/galderma/benzac-ac-mild-strength-2-5-acne-gel/for/oily-acne-prone-skin) — High fit

#### ISDIN Isdinceutics

- [K-Ox Eyes](https://lovi.care/skincare/p/isdin-isdinceutics/k-ox-eyes/for/dry-skin) — High fit

## Questions and answers

### Galderma or ISDIN Isdinceutics: which is better?

Galderma is better for oily and acne-prone skin, as the products on this page have a High Lovi fit for those skin types, though they may cause dryness and irritation. ISDIN Isdinceutics is better for dry and mature skin with its eye product, which achieves a High Lovi fit for those skin types.

[The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### What is the difference between Galderma and ISDIN Isdinceutics?

Galderma is a Swiss brand whose products on this page have a High Lovi fit for oily and acne-prone skin, whereas ISDIN Isdinceutics is a Spanish brand offering an eye product that has a High Lovi fit for dry, sensitive, and mature skin. Galderma [serums](https://lovi.care/skincare/ingredients/serum) help clear acne, but reviewers note they may cause severe dryness and peeling. [Benzoyl peroxide](https://lovi.care/skincare/ingredients/benzoyl-peroxide) decreases acne bacteria, and [adapalene](https://lovi.care/skincare/ingredients/adapalene) helps reduce acne scars.

[Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### Which is more affordable, Galderma or ISDIN Isdinceutics?

The products on this page for Galderma and ISDIN Isdinceutics do not include pricing information, so a direct comparison of affordability cannot be made.

### Which causes fewer breakouts, Galderma or ISDIN Isdinceutics?

Galderma is a better fit for oily and acne-prone skin, with Lovi fit levels rated High for its acne-clearing serums on this page, while ISDIN Isdinceutics only has an average fit for acne-prone skin. Benzoyl peroxide helps clear acne by decreasing bacteria, though reviewers mention that Galderma products may cause severe dryness and peeling.

[The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/)

### Which brand is older, Galderma or ISDIN Isdinceutics, and where were they founded?

ISDIN Isdinceutics is older, having been founded in Spain in 1975, whereas Galderma was founded in Switzerland in 1981.

### Do products from Galderma and ISDIN Isdinceutics contain fragrance?

Galderma products on this page list no fragrance in their ingredients, whereas the ISDIN Isdinceutics product on this page contains fragrance.

### What are the main negative reviews reported for Galderma products?

Shoppers most often report severe dryness and peeling, along with severe irritation and discomfort, when using the products on this page from Galderma.

## Research behind their key ingredients

- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage](https://pubmed.ncbi.nlm.nih.gov/21699266/) Chrysin · Journal of Agricultural and Food Chemistry, 2011
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide, Benzoyl peroxide 25mg g · The Cochrane Database of Systematic Reviews, 2020
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene · American Journal of Clinical Dermatology, 2018
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene · Archives of Dermatological Research, 2022
- [Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15](https://pubmed.ncbi.nlm.nih.gov/32224894/) Silicon dioxide · Antioxidants, 2020
- [Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection](https://pubmed.ncbi.nlm.nih.gov/32395645/) Silicon dioxide · Heliyon, 2020
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023
- [Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/37367119/) Carbomer 940 · Gels, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation](https://pubmed.ncbi.nlm.nih.gov/19566395/) Ascorbyl palmitate · Journal of Microencapsulation, 2010
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- Swiss skincare: [Galderma](https://lovi.care/skincare/brands/galderma)
- Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/brands/isdin-isdinceutics)

## More comparisons

- [SKIN1004 vs Galderma](https://lovi.care/skincare/compare/skin1004-vs-galderma)
- [SKIN1004 vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/skin1004-vs-isdin-isdinceutics)
- [Anua vs Galderma](https://lovi.care/skincare/compare/anua-vs-galderma)
- [Anua vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/anua-vs-isdin-isdinceutics)
- [Medicube vs Galderma](https://lovi.care/skincare/compare/medicube-vs-galderma)
- [Medicube vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/medicube-vs-isdin-isdinceutics)
- [The Ordinary vs Galderma](https://lovi.care/skincare/compare/the-ordinary-vs-galderma)
- [The Ordinary vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/the-ordinary-vs-isdin-isdinceutics)
- [Beauty of Joseon vs Galderma](https://lovi.care/skincare/compare/beauty-of-joseon-vs-galderma)
- [Beauty of Joseon vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/beauty-of-joseon-vs-isdin-isdinceutics)
- [COSRX vs Galderma](https://lovi.care/skincare/compare/cosrx-vs-galderma)
- [COSRX vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/cosrx-vs-isdin-isdinceutics)
- [CeraVe vs Galderma](https://lovi.care/skincare/compare/cerave-vs-galderma)
- [CeraVe vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/cerave-vs-isdin-isdinceutics)
- [La Roche-Posay vs Galderma](https://lovi.care/skincare/compare/la-roche-posay-vs-galderma)
- [La Roche-Posay vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/la-roche-posay-vs-isdin-isdinceutics)
- [Dr. Althea vs Galderma](https://lovi.care/skincare/compare/dr-althea-vs-galderma)
- [Dr. Althea vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/dr-althea-vs-isdin-isdinceutics)
- [Some By Mi vs Galderma](https://lovi.care/skincare/compare/some-by-mi-vs-galderma)
- [Some By Mi vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/some-by-mi-vs-isdin-isdinceutics)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/galderma-vs-isdin-isdinceutics (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/galderma-vs-isdin-isdinceutics
- Ireland: https://lovi.care/skincare/ie/compare/galderma-vs-isdin-isdinceutics
- Germany: https://lovi.care/skincare/de/compare/galderma-vs-isdin-isdinceutics
- France: https://lovi.care/skincare/fr/compare/galderma-vs-isdin-isdinceutics
- Italy: https://lovi.care/skincare/it/compare/galderma-vs-isdin-isdinceutics
- Netherlands: https://lovi.care/skincare/nl/compare/galderma-vs-isdin-isdinceutics
- Spain: https://lovi.care/skincare/es/compare/galderma-vs-isdin-isdinceutics
- Canada: https://lovi.care/skincare/ca/compare/galderma-vs-isdin-isdinceutics
- Australia: https://lovi.care/skincare/au/compare/galderma-vs-isdin-isdinceutics
- Singapore: https://lovi.care/skincare/sg/compare/galderma-vs-isdin-isdinceutics
- Saudi Arabia: https://lovi.care/skincare/sa/compare/galderma-vs-isdin-isdinceutics
- United Arab Emirates: https://lovi.care/skincare/ae/compare/galderma-vs-isdin-isdinceutics