# COSRX vs ISDIN Isdinceutics

Page: https://lovi.care/skincare/compare/cosrx-vs-isdin-isdinceutics

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

COSRX and ISDIN Isdinceutics are two distinct skincare brands offering specialized formulations for varied complexions. The Korean brand is beloved for its thoughtful array of [serums](https://lovi.care/skincare/ingredients/serum), moisturizers, cleansers, and masks featuring [hyaluronic acid](https://lovi.care/skincare/ingredients/hyaluronic-acid), [glycerin](https://lovi.care/skincare/ingredients/glycerin), and [niacinamide](https://lovi.care/skincare/ingredients/niacinamide), which suit oily and oily acne-prone skin best by balancing delicate moisture levels. Meanwhile, the Spanish brand is revered for its targeted eye products and advanced formulas that suit mature, dry, and sensitive skin best due to their gentle yet effective compositions. Ultimately, both differ primarily in their regional origins, primary ingredient concentrations, and the specific skin types they most naturally support.

COSRX is a Korean skincare brand founded in 2013 and owned by Amorepacific Group since 2024.

[koreajoongangdaily.com](https://www.koreajoongangdaily.com/business/amorepacific-ups-global-presence-with-cosrx/11570459) [beautymatter.com](https://beautymatter.com/articles/cosrx-becomes-an-amorepacific-subsidiary) [prnewswire.com](https://www.prnewswire.com/news-releases/amorepacific-incorporates-cosrx-as-a-subsidiary-through-additional-stake-acquisition-301972053.html)

ISDIN Isdinceutics is a Spanish skincare brand founded in 1975 and owned by Puig since 2027.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/)

This page compares some of the most popular COSRX and ISDIN Isdinceutics products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgf473591e63).

### Popular COSRX vs ISDIN Isdinceutics products

#### COSRX

- [Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/dry-skin) — Superior fit — [$15.88 at Amazon](https://www.amazon.com/dp/B00PBX3L7K?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Low pH Good Morning Gel Cleanser](https://lovi.care/skincare/p/cosrx/low-ph-good-morning-gel-cleanser/for/combination-skin) — High fit — [$11.90 at Amazon](https://www.amazon.com/dp/B016NRXO06?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [The 6 Peptide Skin Booster Serum](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/mature-skin) — Superior fit — [$17.50 at Amazon](https://www.amazon.com/dp/B0CCJ3SRB9?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [BHA Blackhead Power Liquid](https://lovi.care/skincare/p/cosrx/bha-blackhead-power-liquid/for/oily-acne-prone-skin) — Superior fit — [$18.94 at Amazon](https://www.amazon.com/dp/B00OZEJ8R8?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [The Hyaluronic Acid 3 Serum](https://lovi.care/skincare/p/cosrx/the-hyaluronic-acid-3-serum/for/combination-skin) — High fit — [$20.99 at Amazon](https://www.amazon.com/dp/B09ZYCVH8N?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Advanced Snail 92 All in One Cream](https://lovi.care/skincare/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — [$16.50 at Amazon](https://www.amazon.com/dp/B01LEJ5MSK?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [AHA/BHA Clarifying Treatment Toner](https://lovi.care/skincare/p/cosrx/aha-bha-clarifying-treatment-toner/for/oily-acne-prone-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B073P6BPF5?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [The Retinol 0.1 Cream](https://lovi.care/skincare/p/cosrx/the-retinol-0-1-cream/for/oily-skin) — High fit — [$22.00 at Amazon](https://www.amazon.com/dp/B0B5DKJ8TS?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

#### ISDIN Isdinceutics

- [K-Ox Eyes](https://lovi.care/skincare/p/isdin-isdinceutics/k-ox-eyes/for/dry-skin) — High fit

## Questions and answers

### COSRX or ISDIN Isdinceutics: which is better?

COSRX offers a much wider range of products that Lovi rates as Superior or High for various skin types, featuring key ingredients like [hyaluronic acid](https://lovi.care/skincare/ingredients/hyaluronic-acid) and [niacinamide](https://lovi.care/skincare/ingredients/niacinamide), whereas ISDIN Isdinceutics only lists a single product on this page.

### What is the difference between COSRX and ISDIN Isdinceutics?

COSRX offers a wide variety of products on this page tailored for oily, oily acne-prone, and combination skin, while ISDIN Isdinceutics is represented by only a single eye product.

### Which is more affordable, COSRX or ISDIN Isdinceutics?

This page does not provide pricing information to compare the affordability of COSRX and ISDIN Isdinceutics.

### Which causes fewer breakouts, COSRX or ISDIN Isdinceutics?

COSRX offers many products that help with acne-prone and oily acne-prone skin, whereas ISDIN Isdinceutics only lists an eye product on this page and does not focus on breakout control.

### How do the founding years and countries of origin compare between COSRX and ISDIN Isdinceutics?

COSRX was founded in South Korea in 2013, whereas ISDIN Isdinceutics originates from Spain, having been founded earlier in 1975.

### Which brand offers a wider variety of skincare products on this page, and how do their product categories differ?

COSRX offers a much wider variety of skincare products on this page, whereas ISDIN Isdinceutics features only a single eye product. The products on this page for COSRX span cleansers, toners, [serums](https://lovi.care/skincare/ingredients/serum), moisturizers, sunscreens, eye products, masks, and treatments.

### How does the use of fragrance differ in the products offered by COSRX versus ISDIN Isdinceutics?

COSRX offers mostly fragrance-free products on this page, whereas all of the ISDIN Isdinceutics products on this page include fragrance.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate, Hyaluronic acid · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Bifidobacterium longum lysate, a new ingredient for reactive skin](https://pubmed.ncbi.nlm.nih.gov/19624730/) 1 · Experimental Dermatology, 2010
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/17314442/) Melaleuca alternifolia tree oil leaf · Indian Journal of Dermatology, Venereology and Leprology, 2007
- [Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics](https://pubmed.ncbi.nlm.nih.gov/35223163/) Collagen · Dermatology Practical & Conceptual, 2022
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage](https://pubmed.ncbi.nlm.nih.gov/21699266/) Chrysin · Journal of Agricultural and Food Chemistry, 2011
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica leaf water, Madecassoside, Madecassic acid, Asiaticoside, Centella asiatica · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy](https://pubmed.ncbi.nlm.nih.gov/39458583/) Centella asiatica leaf water · Pharmaceutics, 2024
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Melaleuca alternifolia tree oil leaf, Aloe barbadensis extract, Propolis extract, Aloe barbadensis leaf water · Clinical Pharmacology, 2018
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Collagen · Current Issues in Molecular Biology, 2024
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face study](https://pubmed.ncbi.nlm.nih.gov/25228478/) Melaleuca alternifolia tree oil leaf · Dermatology, 2014
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Centella asiatica leaf water, Madecassoside, Asiaticoside · Journal of Alternative and Complementary Medicine, 2020
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) N-acetyl glucosamine, Acetyl glucosamine, N-acetyl glucosamine nag · The British Journal of Dermatology, 2010
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) N-acetyl glucosamine, N-acetyl glucosamine nag · Journal of Cosmetic Dermatology, 2007
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Bha beta hydroxy acid, Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Melaleuca alternifolia tree oil leaf · Archives of Dermatological Research, 2022
- [Snail Slime Extracted by a Cruelty Free Method Preserves Viability and Controls Inflammation Occurrence: A Focus on Fibroblasts](https://pubmed.ncbi.nlm.nih.gov/36770889/) Snail secretion filtrate · Molecules, 2023
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Saccharomyces ferment, Galactomyces ferment filtrate · Journal of Clinical Medicine, 2021
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Phyllanthus emblica L. (amla) branch: A safe and effective ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/34522633/) 1 · Journal of Traditional and Complementary Medicine, 2021
- [In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract](https://pubmed.ncbi.nlm.nih.gov/32812663/) Rice extract · International Journal of Cosmetic Science, 2020
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf water, Madecassoside, Centella asiatica · Molecules, 2023
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Bha beta hydroxy acid, Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [High-Payload Nanosuspension of Centella asiatica Extract for Improved Skin Delivery with No Irritation](https://pubmed.ncbi.nlm.nih.gov/34764648/) Asiaticoside · International Journal of Nanomedicine, 2021
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Bha beta hydroxy acid, Salicylic acid · Journal of Drugs in Dermatology, 2023
- [The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols](https://pubmed.ncbi.nlm.nih.gov/21585401/) 2-hexanediol · International Journal of Cosmetic Science, 2011
- [Effects of a lotion containing probiotic ferment lysate as the main functional ingredient on enhancing skin barrier: a randomized, self-control study](https://pubmed.ncbi.nlm.nih.gov/37803101/) 1 · Scientific Reports, 2023
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Pinus pinaster bark extract · Journal of Cosmetic Dermatology, 2022
- [Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: Invitro and invivo human studies](https://pubmed.ncbi.nlm.nih.gov/37681127/) Alpha-arbutin · Heliyon, 2023
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark water bark · Journal of Cosmetic Dermatology, 2010
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow water bark · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow water bark · Planta Medica, 2019
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Standardized extract of wild apple fruit in alkyl-polyglucoside-based cosmetic cream - estimation of stability, safety, antioxidant activity and efficiency](https://pubmed.ncbi.nlm.nih.gov/29723433/) Pyrus malus fruit water · International Journal of Cosmetic Science, 2018
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Asiatic acid · International Journal of Pharmaceutics, 2024
- [Effect of facial application of essence containing royal jelly extract on stratum corneum moisture content: A placebo-controlled, double-blind, parallel-group study](https://pubmed.ncbi.nlm.nih.gov/35778882/) Royal jelly extract · Journal of Cosmetic Dermatology, 2022
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) N-acetyl glucosamine nag · Advanced Pharmaceutical Bulletin, 2016
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of Panax ginseng formulation on skin microbiota: A randomized, split face comparative clinical study](https://pubmed.ncbi.nlm.nih.gov/35509819/) 2-hexanediol · Journal of Ginseng Research, 2022
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Safety of a New Cosmeceutical Regimen Based on the Combination of Snail Secretion Filtrate and Snail Egg Extract to Improve Signs of Skin Aging](https://pubmed.ncbi.nlm.nih.gov/32308795/) Snail secretion filtrate · The Journal of Clinical and Aesthetic Dermatology, 2020
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 3-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Galactomyces ferment filtrate · Journal of Clinical Medicine, 2022
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) 2-hexanediol · Cutaneous and Ocular Toxicology, 2009
- [Salicin and Hederacoside C-Based Extracts and UV-Absorbers Co-Loaded into Bioactive Lipid Nanocarriers with Promoted Skin Antiaging and Hydrating Efficacy](https://pubmed.ncbi.nlm.nih.gov/35889587/) Willow bark water bark · Nanomaterials, 2022
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use](https://pubmed.ncbi.nlm.nih.gov/30040516/) N-acetyl glucosamine nag · Journal of Cosmetic and Laser Therapy, 2019
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation](https://pubmed.ncbi.nlm.nih.gov/19566395/) Ascorbyl palmitate · Journal of Microencapsulation, 2010
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A randomized placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/35763437/) Snail secretion filtrate · Journal of Cosmetic Dermatology, 2022
- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Saccharomyces ferment, Galactomyces ferment filtrate · Journal of Clinical Medicine, 2023
- [Salicin regulates the expression of functional 'youth gene clusters' to reflect a more youthful gene expression profile](https://pubmed.ncbi.nlm.nih.gov/21449910/) Willow bark water bark · International Journal of Cosmetic Science, 2011
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects](https://pubmed.ncbi.nlm.nih.gov/31347768/) Arginine · Journal of Cosmetic Dermatology, 2020
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate, Octocrylene · Archives of Dermatological Research, 2024
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Investigating the Effects of a Manuka Honey, Royal Jelly, and Bee Venom-Derived Face Serum on Skin Health and Signs of Aging](https://pubmed.ncbi.nlm.nih.gov/40291268/) Royal jelly extract · Cureus, 2025
- [Skin moisturization by hydrogenated polyisobutene--quantitative and visual evaluation](https://pubmed.ncbi.nlm.nih.gov/19296892/) Polyisobutylene · Journal of Cosmetic Science, 2009
- [Clinical efficacy of biocellulose, carboxymethyl cellulose and normal saline dressing in epidermolysis bullosa](https://pubmed.ncbi.nlm.nih.gov/31600103/) Cellulose gum · Journal of Wound Care, 2019
- [Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu](https://pubmed.ncbi.nlm.nih.gov/42573538/) Copper tripeptide-1 · Skin Research and Technology, 2026
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Dipeptide diaminobutyroyl benzylamide diacetate · International Journal of Cosmetic Science, 2026
- [Effects of an ultraviolet B radiation absorber on photocarcinogenesis in hairless albino mice](https://pubmed.ncbi.nlm.nih.gov/19365102/) Ethylhexyl triazone · Skin Pharmacology and Physiology, 2009
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Galactomyces ferment filtrate · Skinmed, 2021
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## The brands

- Korean skincare: [COSRX](https://lovi.care/skincare/brands/cosrx)
- Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/brands/isdin-isdinceutics)

## More comparisons

- [SKIN1004 vs COSRX](https://lovi.care/skincare/compare/skin1004-vs-cosrx)
- [SKIN1004 vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/skin1004-vs-isdin-isdinceutics)
- [Anua vs COSRX](https://lovi.care/skincare/compare/anua-vs-cosrx)
- [Anua vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/anua-vs-isdin-isdinceutics)
- [Medicube vs COSRX](https://lovi.care/skincare/compare/medicube-vs-cosrx)
- [Medicube vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/medicube-vs-isdin-isdinceutics)
- [The Ordinary vs COSRX](https://lovi.care/skincare/compare/the-ordinary-vs-cosrx)
- [The Ordinary vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/the-ordinary-vs-isdin-isdinceutics)
- [Beauty of Joseon vs COSRX](https://lovi.care/skincare/compare/beauty-of-joseon-vs-cosrx)
- [Beauty of Joseon vs ISDIN Isdinceutics](https://lovi.care/skincare/compare/beauty-of-joseon-vs-isdin-isdinceutics)
- [COSRX vs CeraVe](https://lovi.care/skincare/compare/cosrx-vs-cerave)
- [COSRX vs La Roche-Posay](https://lovi.care/skincare/compare/cosrx-vs-la-roche-posay)
- [COSRX vs Dr. Althea](https://lovi.care/skincare/compare/cosrx-vs-dr-althea)
- [COSRX vs Some By Mi](https://lovi.care/skincare/compare/cosrx-vs-some-by-mi)
- [COSRX vs Torriden](https://lovi.care/skincare/compare/cosrx-vs-torriden)
- [COSRX vs celimax](https://lovi.care/skincare/compare/cosrx-vs-celimax)
- [COSRX vs Purito](https://lovi.care/skincare/compare/cosrx-vs-purito)
- [COSRX vs Cetaphil](https://lovi.care/skincare/compare/cosrx-vs-cetaphil)
- [COSRX vs Paula's Choice](https://lovi.care/skincare/compare/cosrx-vs-paula-s-choice)
- [COSRX vs Neutrogena](https://lovi.care/skincare/compare/cosrx-vs-neutrogena)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/cosrx-vs-isdin-isdinceutics (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/cosrx-vs-isdin-isdinceutics
- Ireland: https://lovi.care/skincare/ie/compare/cosrx-vs-isdin-isdinceutics
- Germany: https://lovi.care/skincare/de/compare/cosrx-vs-isdin-isdinceutics
- France: https://lovi.care/skincare/fr/compare/cosrx-vs-isdin-isdinceutics
- Italy: https://lovi.care/skincare/it/compare/cosrx-vs-isdin-isdinceutics
- Netherlands: https://lovi.care/skincare/nl/compare/cosrx-vs-isdin-isdinceutics
- Spain: https://lovi.care/skincare/es/compare/cosrx-vs-isdin-isdinceutics
- Canada: https://lovi.care/skincare/ca/compare/cosrx-vs-isdin-isdinceutics
- Australia: https://lovi.care/skincare/au/compare/cosrx-vs-isdin-isdinceutics
- Singapore: https://lovi.care/skincare/sg/compare/cosrx-vs-isdin-isdinceutics
- Saudi Arabia: https://lovi.care/skincare/sa/compare/cosrx-vs-isdin-isdinceutics
- United Arab Emirates: https://lovi.care/skincare/ae/compare/cosrx-vs-isdin-isdinceutics