# Clinique vs Simple

Page: https://lovi.care/skincare/compare/clinique-vs-simple

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Clinique and Simple are heritage skincare lines known for their reliable moisturizers and makeup removers formulated with [glycerin](https://lovi.care/skincare/ingredients/glycerin). The American brand pairs this ingredient with [hyaluronic acid](https://lovi.care/skincare/ingredients/hyaluronic-acid) and [caffeine](https://lovi.care/skincare/ingredients/caffeine) to suit dry, sensitive, and oily skin types, whereas the British brand incorporates [niacinamide](https://lovi.care/skincare/ingredients/niacinamide) to best care for acne-prone and oily complexions. Ultimately, the former offers targeted solutions for diverse aging and textural concerns, while the latter focuses on gentle, everyday maintenance.

Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Clinique) [elcompanies.com](https://www.elcompanies.com/en/who-we-are/our-heritage) [businesswire.com](https://www.businesswire.com/news/home/20261019083802/en/The-Este-Lauder-Companies-Appoints-Krista-Lee-Berger-Senior-Vice-President-Global-Marketing-Clinique) [glossy.co](https://www.glossy.co/beauty/glossy-pop-newsletter-clinique-launches-first-ever-creator-led-campaign/)

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

This page compares some of the most popular Clinique and Simple products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgee7b0566fb).

### Popular Clinique vs Simple products

#### Simple

- [Micellar Water](https://lovi.care/skincare/p/simple/micellar-water/for/mature-skin) — Average fit — [$19.50 at Amazon](https://www.amazon.com/dp/B071XCT81N?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit — [$20.00 at Amazon](https://www.amazon.com/dp/B0G4DWBM9V?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Hydrating Light Moisturiser](https://lovi.care/skincare/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [$6.24 at Amazon](https://www.amazon.com/dp/B000LQX6XG?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [$7.90 at Amazon](https://www.amazon.com/dp/B000LQUA6M?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [$6.40 at Amazon](https://www.amazon.com/dp/B000LNHB6M?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit — [$15.64 at Amazon](https://www.amazon.com/dp/B076TBCFWR?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [$6.67 at Amazon](https://www.amazon.com/dp/B076V2D94Y?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

#### Clinique

- [moisture surge](https://lovi.care/skincare/p/clinique/moisture-surge/for/sensitive-skin) — High fit
- [Take The Day Off Cleansing Balm](https://lovi.care/skincare/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [$58.00 at Amazon](https://www.amazon.com/dp/B09TWCDV9T?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Lotion+](https://lovi.care/skincare/p/clinique/dramatically-different-moisturizing-lotion/for/dry-skin) — Average fit — [$36.75 at Amazon](https://www.amazon.com/dp/B00JGLEQAO?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [All About Eyes](https://lovi.care/skincare/p/clinique/all-about-eyes/for/dry-skin) — High fit — [$66.00 at Amazon](https://www.amazon.com/dp/B001IZ0ZFQ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [$25.50 at Amazon](https://www.amazon.com/dp/B003JRI3OG?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [$109.00 at Amazon](https://www.amazon.com/dp/B09FG8TJDD?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Moisture Surge Overnight Mask](https://lovi.care/skincare/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [$47.00 at Amazon](https://www.amazon.com/dp/B00HSZRQQQ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Clarifying Lotion 2](https://lovi.care/skincare/p/clinique/clarifying-lotion-2/for/oily-acne-prone-skin) — Average fit — [$37.00 at Amazon](https://www.amazon.com/dp/B000H74MNW?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

## People Say

Clinique

Simple

- Sensitive Skin Friendly Mostly Mentioned Mostly Mentioned “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water” “The only cleanser that doesn't turn my face red. — Simple Micellar Water” “no artificial perfume — Simple Hydrating Light Moisturiser” “never irritated my eyes — Clinique All About Eyes”
- Hydration and Plumping Often Mentioned Mostly Mentioned “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+” “skin feels soft and smooth — Clinique Moisture Surge Overnight Mask” “banished dryness within days — Simple Replenishing Rich Moisturiser” “Instantly boosts skin's hydration... face doesn't feel dry and tight. — Simple Micellar Cleansing Water”
- Lightweight and Fast Absorbing Often Mentioned Often Mentioned “sinks in immediately — Clinique moisture surge” “sinks in instantly — Clinique Dramatically Different Moisturizing Gel” “sinks in instantly — Simple Water Boost Hydrating Gel Cream” “absorbs very quickly — Simple Hydrating Light Moisturiser”
- Good Makeup Base Often Mentioned Sometimes Noted “foundation glides on — Clinique moisture surge” “holds concealer in place — Clinique All About Eyes” “makeup lays well — Simple Hydrating Light Moisturiser” “works well under foundation — Simple Replenishing Rich Moisturiser”
- Value and Options Rarely Noted Often Mentioned “great value for money — Simple Kind to Skin Soothing Facial Toner” “super affordable — Simple Hydrating Light Moisturiser” “Can't beat the price for the quality. — Simple Micellar Water” “lasts forever — Clinique all about clean”
- Luxurious Texture and Glow Often Mentioned Rarely Noted “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum” “wake up glowing — Clinique Moisture Surge Overnight Mask” “absorbs quickly — Clinique Moisture Surge Overnight Mask” “removes last traces of makeup — Simple Kind to Skin Soothing Facial Toner”
- Causes Breakouts Sometimes Noted Sometimes Noted “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+” “gave me tiny bumps — Clinique moisture surge” “Gave me tiny bumps on my forehead. — Simple Micellar Water” “caused major breakouts — Simple Hydrating Light Moisturiser”
- Price and Value Complaints Often Mentioned Not noted “jar is too small for the cost — Clinique moisture surge”
- Insufficient Hydration Sometimes Noted Sometimes Noted “skin felt tight — Clinique Dramatically Different Moisturizing Gel” “skin felt tight after an hour — Clinique moisture surge” “not moisturizing enough — Simple Hydrating Light Moisturiser” “skin felt tight after an hour — Simple Water Boost Hydrating Gel Cream”

### Clinique vs Simple routines for dry skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/p/simple/refreshing-facial-wash/for/dry-skin) — Low fit — [$7.90 at Amazon](https://www.amazon.com/dp/B000LQUA6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [$16.99 at Amazon](https://www.amazon.com/dp/B08Q6WZ6J1?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [$6.40 at Amazon](https://www.amazon.com/dp/B000LNHB6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [$15.99 at Amazon](https://www.amazon.com/dp/B0DKJ63Y6B?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/p/simple/micellar-cleansing-water/for/dry-skin) — High fit — [$20.00 at Amazon](https://www.amazon.com/dp/B0G4DWBM9V?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — [$39.00 at Amazon](https://www.amazon.com/dp/B08H4QPM19?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09XWPL5VN?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [all about clean](https://lovi.care/skincare/p/clinique/all-about-clean/for/dry-skin) — Warning fit — [$43.00 at Amazon](https://www.amazon.com/dp/B002RBTB8C?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [$16.99 at Amazon](https://www.amazon.com/dp/B08Q6WZ6J1?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Smart Clinical Repair Lifting Face + Neck Cream](https://lovi.care/skincare/p/clinique/smart-clinical-repair-lifting-face-neck-cream/for/dry-skin) — High fit — [$80.25 at Amazon](https://www.amazon.com/dp/B0DFWJNR6P?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [$15.99 at Amazon](https://www.amazon.com/dp/B0DKJ63Y6B?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [$58.00 at Amazon](https://www.amazon.com/dp/B09TWCDV9T?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/dry-skin) — Average fit — [$109.00 at Amazon](https://www.amazon.com/dp/B09FG8TJDD?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Moisture Surge Overnight Mask](https://lovi.care/skincare/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [$47.00 at Amazon](https://www.amazon.com/dp/B00HSZRQQQ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · $128.28 · 83% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B08Q6WZ6J1&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B0DKJ63Y6B&Quantity.4=1&ASIN.5=B0G4DWBM9V&Quantity.5=1&ASIN.6=B08H4QPM19&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine-20) [Buy Clinique routine · $370.23 · 74% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B002RBTB8C&Quantity.1=1&ASIN.2=B08Q6WZ6J1&Quantity.2=1&ASIN.3=B0DFWJNR6P&Quantity.3=1&ASIN.4=B0DKJ63Y6B&Quantity.4=1&ASIN.5=B09TWCDV9T&Quantity.5=1&ASIN.6=B09FG8TJDD&Quantity.6=1&ASIN.7=B00HSZRQQQ&Quantity.7=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 99% fit](https://lovi.care/skincare/skin/dry-skin)

### Clinique vs Simple routines for oily skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/p/simple/refreshing-facial-wash/for/oily-skin) — Average fit — [$7.90 at Amazon](https://www.amazon.com/dp/B000LQUA6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [$15.60 at Amazon](https://www.amazon.com/dp/B08125WDCF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/p/simple/replenishing-rich-moisturiser/for/oily-skin) — Average fit — [$6.40 at Amazon](https://www.amazon.com/dp/B000LNHB6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B00F97FHAW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/p/simple/micellar-cleansing-water/for/oily-skin) — High fit — [$20.00 at Amazon](https://www.amazon.com/dp/B0G4DWBM9V?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [$28.42 at Amazon](https://www.amazon.com/dp/B00KH6QX08?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — [$39.00 at Amazon](https://www.amazon.com/dp/B08H4QPM19?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — [$79.00 at Amazon](https://www.amazon.com/dp/B0DQ5XJ5FK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [Redness Solutions Soothing Cleanser](https://lovi.care/skincare/p/clinique/redness-solutions-soothing-cleanser/for/oily-skin) — Average fit — [$32.00 at Amazon](https://www.amazon.com/dp/B0016LU1BK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [$15.60 at Amazon](https://www.amazon.com/dp/B08125WDCF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [$25.50 at Amazon](https://www.amazon.com/dp/B003JRI3OG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B00F97FHAW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/p/clinique/take-the-day-off-cleansing-balm/for/oily-skin) — Low fit — [$58.00 at Amazon](https://www.amazon.com/dp/B09TWCDV9T?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/p/clinique/clarifying-lotion-2/for/oily-skin) — Average fit — [$37.00 at Amazon](https://www.amazon.com/dp/B000H74MNW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-skin) — Average fit — [$109.00 at Amazon](https://www.amazon.com/dp/B09FG8TJDD?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — [$79.00 at Amazon](https://www.amazon.com/dp/B0DQ5XJ5FK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · $280.29 · 88% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B00F97FHAW&Quantity.4=1&ASIN.5=B0G4DWBM9V&Quantity.5=1&ASIN.6=B00KH6QX08&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B0DQ5XJ5FK&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [Buy Clinique routine · $440.07 · 78% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B0016LU1BK&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B003JRI3OG&Quantity.3=1&ASIN.4=B00F97FHAW&Quantity.4=1&ASIN.5=B09TWCDV9T&Quantity.5=1&ASIN.6=B000H74MNW&Quantity.6=1&ASIN.7=B09FG8TJDD&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B0DQ5XJ5FK&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 98% fit](https://lovi.care/skincare/skin/oily-skin)

### Clinique vs Simple routines for combination skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/p/simple/refreshing-facial-wash/for/combination-skin) — Average fit — [$7.90 at Amazon](https://www.amazon.com/dp/B000LQUA6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [$25.60 at Amazon](https://www.amazon.com/dp/B008EPPIQ4?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/p/simple/replenishing-rich-moisturiser/for/combination-skin) — Average fit — [$6.40 at Amazon](https://www.amazon.com/dp/B000LNHB6M?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B00F97FHAW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/p/simple/micellar-cleansing-water/for/combination-skin) — Average fit — [$20.00 at Amazon](https://www.amazon.com/dp/B0G4DWBM9V?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [$18.90 at Amazon](https://www.amazon.com/dp/B09V7Z4TJG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — [$39.00 at Amazon](https://www.amazon.com/dp/B08H4QPM19?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [$58.00 at Amazon](https://www.amazon.com/dp/B015RRNQCY?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [all about clean](https://lovi.care/skincare/p/clinique/all-about-clean/for/combination-skin) — Low fit — [$43.00 at Amazon](https://www.amazon.com/dp/B002RBTB8C?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [$25.60 at Amazon](https://www.amazon.com/dp/B008EPPIQ4?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/p/clinique/dramatically-different-moisturizing-gel/for/combination-skin) — Average fit — [$25.50 at Amazon](https://www.amazon.com/dp/B003JRI3OG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [$14.97 at Amazon](https://www.amazon.com/dp/B00F97FHAW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/p/clinique/take-the-day-off-cleansing-balm/for/combination-skin) — Low fit — [$58.00 at Amazon](https://www.amazon.com/dp/B09TWCDV9T?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/p/clinique/clarifying-lotion-2/for/combination-skin) — Average fit — [$37.00 at Amazon](https://www.amazon.com/dp/B000H74MNW?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/combination-skin) — Average fit — [$109.00 at Amazon](https://www.amazon.com/dp/B09FG8TJDD?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [$58.00 at Amazon](https://www.amazon.com/dp/B015RRNQCY?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · $259.77 · 87% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B00F97FHAW&Quantity.4=1&ASIN.5=B0G4DWBM9V&Quantity.5=1&ASIN.6=B09V7Z4TJG&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B015RRNQCY&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [Buy Clinique routine · $440.07 · 74% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B002RBTB8C&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B003JRI3OG&Quantity.3=1&ASIN.4=B00F97FHAW&Quantity.4=1&ASIN.5=B09TWCDV9T&Quantity.5=1&ASIN.6=B000H74MNW&Quantity.6=1&ASIN.7=B09FG8TJDD&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B015RRNQCY&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 97% fit](https://lovi.care/skincare/skin/combination-skin)

## Questions and answers

### Clinique or Simple: which is better?

Simple is better for value and options, whereas Clinique is noted for luxurious texture and glow, while both brands offer equal levels of hydration, lightweight absorption, and makeup base performance. Reviewers note that Simple offers budget-friendly moisturizers and sensitive-skin-friendly makeup removers, while Clinique features hydrating and fast-absorbing formulas.

### What is the difference between Clinique and Simple?

Simple tends to be more sensitive-skin friendly and offers better value with more options, while Clinique provides a more luxurious texture and glow. Both brands perform similarly for hydration, lightweight absorption, and use as a makeup base.

### Clinique or Simple for dry skin?

Simple is the better choice for dry skin because its routine fit is High, whereas Clinique is Average. Both brands offer products with no fragrance in their ingredients.

### Clinique or Simple: which cleanser is better?

Simple features a better cleanser on the products on this page, as the Refreshing Facial Wash achieves an average fit for acne-prone, sensitive, and oily skin types, whereas the Clinique all about clean cleanser receives warning and low fit levels for dry and sensitive skin. The products on this page for both brands list no fragrance in their ingredients.

### Which is more affordable, Clinique or Simple?

Simple is more affordable, as reviewers on the products on this page often mention complaints regarding the high price point of Clinique. Simple provides lightweight, value-friendly moisturizers.

### Which brand has fragrance-free products, Clinique or Simple?

Both Clinique and Simple have fragrance-free products, as every product listed on this page for both brands contains no fragrance in its ingredients.

### Clinique or Simple for oily skin?

Both Clinique and Simple are good options for oily skin, as the products on this page achieve a High fit level for this skin type in their brand-focused routines. Reviewers note that Clinique offers oil-controlling and smoothing moisturizers, while Simple provides lightweight, value-friendly moisturizers.

### Clinique or Simple: which moisturizer is better?

Simple offers better-fitting daily moisturizers on this page for most users, while Clinique provides higher-level targeted options for specific concerns like mature or dry sensitive skin. Reviewers note that Simple products tend to be more value-friendly, whereas Clinique is often associated with a higher price point.

### Clinique or Simple for sensitive skin?

Both Clinique and Simple achieve an equal Lovi fit level of High for sensitive skin. The products on this page for both brands list no fragrance in their ingredients, making them gentle choices.

### Clinique or Simple for acne-prone skin?

Both Clinique and Simple fit acne-prone skin well, as the products on this page achieve a High Lovi fit level for this skin type. Reviewers note that Simple offers value-friendly moisturizers, while Clinique provides hydrating and oil-controlling formulas.

### Clinique or Simple for dry sensitive skin?

Clinique is rated High for dry sensitive skin on this page, while Simple is also rated High. Both brands feature fragrance-free products, but Clinique offers targeted options like the Redness Solutions Soothing Cleanser, whereas Simple is noted for budget-friendly hydration.

### Clinique or Simple for mature skin?

Clinique is a better fit for mature skin, offering high-level product options and targeted anti-aging formulations on this page. Reviewers frequently note Clinique for its luxurious texture and glow, and its key ingredients include [hyaluronic acid](https://lovi.care/skincare/ingredients/hyaluronic-acid) and [caffeine](https://lovi.care/skincare/ingredients/caffeine), which help address signs of skin aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Skin Pharmacology and Physiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23075568/)

## Research behind their key ingredients

- [Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology](https://pubmed.ncbi.nlm.nih.gov/19169201/) Squalene · Molecules, 2009
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Micro-acid complex · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Protecting skin photoaging by NF-kappaB inhibitor](https://pubmed.ncbi.nlm.nih.gov/20540695/) Magnolia officinalis bark extract · Current Drug Metabolism, 2010
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf water, Aloe barbadensis · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Effect of 30% Supramolecular Salicylic Acid Peel on Skin Microbiota and Inflammation in Patients with Moderate-to-Severe Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/36350527/) Micro-acid complex · Dermatology and Therapy, 2023
- [Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy](https://pubmed.ncbi.nlm.nih.gov/36985709/) Polygonum cuspidatum root extract · Molecules, 2023
- [Role of Resveratrol in Regulating Cutaneous Functions](https://pubmed.ncbi.nlm.nih.gov/32382280/) Polygonum cuspidatum root extract · Evidence-based Complementary and Alternative Medicine, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB](https://pubmed.ncbi.nlm.nih.gov/17346696/) Magnolia officinalis bark extract · European Journal of Pharmacology, 2007
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results](https://pubmed.ncbi.nlm.nih.gov/39810881/) Probiotic technology · Journal of Experimental Pharmacology, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid, Micro-acid complex · Journal of Cosmetic Dermatology, 2024
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Dimethoxytolyl propylresorcinol · Journal of Cosmetic Dermatology, 2021
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Multi-peptides · Journal of Cosmetic Dermatology, 2010
- [Algae extract protection effect on oxidized protein level in human stratum corneum](https://pubmed.ncbi.nlm.nih.gov/15247018/) Algae extract · Annals of the New York Academy of Sciences, 2004
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate](https://pubmed.ncbi.nlm.nih.gov/21772026/) Sesamum indicum oil · International Journal of Toxicology, 2011
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride, Capric triglyceride · Life, 2023
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Effects of a Postbiotic Saccharomyces and Lactobacillus Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome](https://pubmed.ncbi.nlm.nih.gov/37767337/) Lactobacillus ferment · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Laminaria digitata extract · International Journal of Cosmetic Science, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Saccharide isomerate · Lasers in Medical Science, 2025
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Simmondsia chinensis (jojoba) cake fermentation: A new, sustainable technology for advanced skin and scalp care ingredients](https://pubmed.ncbi.nlm.nih.gov/42698229/) Lactobacillus ferment · International Journal of Cosmetic Science, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023

## The brands

- American skincare: [Clinique](https://lovi.care/skincare/brands/clinique)
- British skincare: [Simple](https://lovi.care/skincare/brands/simple)

## More comparisons

- [SKIN1004 vs Clinique](https://lovi.care/skincare/compare/skin1004-vs-clinique)
- [SKIN1004 vs Simple](https://lovi.care/skincare/compare/skin1004-vs-simple)
- [Anua vs Clinique](https://lovi.care/skincare/compare/anua-vs-clinique)
- [Anua vs Simple](https://lovi.care/skincare/compare/anua-vs-simple)
- [Medicube vs Clinique](https://lovi.care/skincare/compare/medicube-vs-clinique)
- [Medicube vs Simple](https://lovi.care/skincare/compare/medicube-vs-simple)
- [The Ordinary vs Clinique](https://lovi.care/skincare/compare/the-ordinary-vs-clinique)
- [The Ordinary vs Simple](https://lovi.care/skincare/compare/the-ordinary-vs-simple)
- [Beauty of Joseon vs Clinique](https://lovi.care/skincare/compare/beauty-of-joseon-vs-clinique)
- [Beauty of Joseon vs Simple](https://lovi.care/skincare/compare/beauty-of-joseon-vs-simple)
- [COSRX vs Clinique](https://lovi.care/skincare/compare/cosrx-vs-clinique)
- [COSRX vs Simple](https://lovi.care/skincare/compare/cosrx-vs-simple)
- [CeraVe vs Clinique](https://lovi.care/skincare/compare/cerave-vs-clinique)
- [CeraVe vs Simple](https://lovi.care/skincare/compare/cerave-vs-simple)
- [La Roche-Posay vs Clinique](https://lovi.care/skincare/compare/la-roche-posay-vs-clinique)
- [La Roche-Posay vs Simple](https://lovi.care/skincare/compare/la-roche-posay-vs-simple)
- [Dr. Althea vs Clinique](https://lovi.care/skincare/compare/dr-althea-vs-clinique)
- [Dr. Althea vs Simple](https://lovi.care/skincare/compare/dr-althea-vs-simple)
- [Some By Mi vs Clinique](https://lovi.care/skincare/compare/some-by-mi-vs-clinique)
- [Some By Mi vs Simple](https://lovi.care/skincare/compare/some-by-mi-vs-simple)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/clinique-vs-simple (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/clinique-vs-simple
- Ireland: https://lovi.care/skincare/ie/compare/clinique-vs-simple
- Germany: https://lovi.care/skincare/de/compare/clinique-vs-simple
- France: https://lovi.care/skincare/fr/compare/clinique-vs-simple
- Italy: https://lovi.care/skincare/it/compare/clinique-vs-simple
- Netherlands: https://lovi.care/skincare/nl/compare/clinique-vs-simple
- Spain: https://lovi.care/skincare/es/compare/clinique-vs-simple
- Canada: https://lovi.care/skincare/ca/compare/clinique-vs-simple
- Australia: https://lovi.care/skincare/au/compare/clinique-vs-simple
- Singapore: https://lovi.care/skincare/sg/compare/clinique-vs-simple
- Saudi Arabia: https://lovi.care/skincare/sa/compare/clinique-vs-simple
- United Arab Emirates: https://lovi.care/skincare/ae/compare/clinique-vs-simple