# Cetaphil vs ISDIN

Page: https://lovi.care/skincare/compare/cetaphil-vs-isdin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Cetaphil and ISDIN are well-regarded skincare brands originating from the United States and Spain, respectively. The American brand is widely loved for its thoughtful range of cleansers, moisturizers, [serums](https://lovi.care/skincare/ingredients/serum), sunscreens, and more, which are carefully formulated with nourishing ingredients like [glycerin](https://lovi.care/skincare/ingredients/glycerin), [niacinamide](https://lovi.care/skincare/ingredients/niacinamide), and [panthenol](https://lovi.care/skincare/ingredients/panthenol) to suit combination skin and acne-prone skin best. Conversely, the Spanish brand is loved by skincare enthusiasts for its elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products that suit dry skin and sensitive skin best by providing gentle daily comfort and dependable protection. While both offer standout solutions for specific concerns such as acne-prone skin, dark spots, and mature skin, they differ primarily in their core compositions and the specific skin types they target.

Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Cetaphil) [cetaphil.co.uk](https://www.cetaphil.co.uk/why-cetaphil/our-story.html)

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

This page compares some of the most popular Cetaphil and ISDIN products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgea35a0f0fd).

### Popular Cetaphil vs ISDIN products

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [$46.00 at Amazon](https://www.amazon.com/dp/B0CV8716J5?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [$38.00 at Amazon](https://www.amazon.com/dp/B0DWXXJ9Q1?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/p/isdin/k-ox-eyes/for/dry-skin) — High fit — [$106.00 at Amazon](https://www.amazon.com/dp/B01BMLQ4JQ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Hyaluronic Concentrate](https://lovi.care/skincare/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [$115.00 at Amazon](https://www.amazon.com/dp/B01BMLQ086?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [$185.00 at Amazon](https://www.amazon.com/dp/B0CC9W3VWR?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

#### Cetaphil

- [Gentle Skin Cleanser](https://lovi.care/skincare/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [$13.44 at Amazon](https://www.amazon.com/dp/B099N3NM61?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Moisturizing Cream](https://lovi.care/skincare/p/cetaphil/moisturizing-cream/for/dry-skin) — Average fit — [$13.47 at Amazon](https://www.amazon.com/dp/B00BMJTOZK?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Daily Facial Cleanser](https://lovi.care/skincare/p/cetaphil/daily-facial-cleanser/for/oily-skin) — Superior fit — [$11.88 at Amazon](https://www.amazon.com/dp/B09Y4HHY1P?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Moisturizing Lotion](https://lovi.care/skincare/p/cetaphil/moisturizing-lotion/for/sensitive-skin) — Average fit — [$10.49 at Amazon](https://www.amazon.com/dp/B0B4WMTYYK?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Gentle Exfoliating SA Cleanser](https://lovi.care/skincare/p/cetaphil/gentle-exfoliating-sa-cleanser/for/acne-prone-skin) — High fit — [$9.97 at Amazon](https://www.amazon.com/dp/B0CZDDGCQL?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Moisturising Cream](https://lovi.care/skincare/p/cetaphil/moisturising-cream/for/dry-sensitive-skin) — Average fit
- [Gentle Cleansing Bar](https://lovi.care/skincare/p/cetaphil/gentle-cleansing-bar/for/dry-skin) — High fit — [$18.48 at Amazon](https://www.amazon.com/dp/B08NWK2P1J?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Extra Gentle Daily Scrub](https://lovi.care/skincare/p/cetaphil/extra-gentle-daily-scrub/for/sensitive-skin) — Superior fit — [$9.47 at Amazon](https://www.amazon.com/dp/B0GVVV79RX?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

## People Say

Cetaphil

ISDIN

- Gentle for sensitive skin Mostly Mentioned Often Mentioned “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser” “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser” “cleans without stripping — Cetaphil Daily Facial Cleanser” “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- Lightweight and non-greasy Often Mentioned Mostly Mentioned “absorbs instantly — ISDIN Eryfotona Actinica” “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water” “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate” “absorbs instantly — Cetaphil Moisturizing Lotion”
- Hydrating and non-stripping Mostly Mentioned Mostly Mentioned “cleared up flaky skin — Cetaphil Moisturizing Cream” “healed my dry patches — Cetaphil Moisturising Cream” “Improved moisture and texture — ISDIN Hyaluronic Moisture” “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- Skin smoothing and texture improvements Sometimes Noted Rarely Noted “Skin felt softer after one use — Cetaphil Gentle Exfoliating SA Cleanser” “Micro-fine granules don't irritate — Cetaphil Extra Gentle Daily Scrub” “skin was much smoother — ISDIN Retinal Intense Serum”
- Versatile use and daily cleansing Often Mentioned Not noted “great for face and body — Cetaphil Moisturizing Cream” “recommended by my derm — Cetaphil Daily Facial Cleanser” “removes excess oil — Cetaphil Daily Facial Cleanser”
- Brightening and complexion benefits Rarely Noted Sometimes Noted “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum” “skin looks immediately luminous — ISDIN K-Ox Eyes” “skin looks more radiant — Cetaphil Vitamin C Serum”
- Packaging and price complaints Rarely Noted Mostly Mentioned “hate dipping fingers in — Cetaphil Moisturising Cream” “wish it had a pump — Cetaphil Moisturizing Cream” “expensive for drugstore — Cetaphil Moisturizing Cream” “very expensive — ISDIN Eryfotona Actinica”
- Strong scent or fragrance concerns Sometimes Noted Often Mentioned “Overpowering masking fragrance — Cetaphil Gentle Cleansing Bar” “Scent is overwhelmingly artificial. — Cetaphil Oily Skin Cleanser” “smell is overpowering — ISDIN Eryfotona Actinica”
- Formula changes and irritation Sometimes Noted Rarely Noted “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum” “slight peeling — ISDIN Retinal Intense Serum” “New version burns my face. — Cetaphil Gentle Skin Cleanser”

### Cetaphil vs ISDIN routines for dry skin

#### ISDIN-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [$19.99 at Amazon](https://www.amazon.com/dp/B01N7T7JKJ?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [$16.99 at Amazon](https://www.amazon.com/dp/B08Q6WZ6J1?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — [$22.00 at Amazon](https://www.amazon.com/dp/B0BTPGPK7H?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Fusion Water](https://lovi.care/skincare/p/isdin/fusion-water/for/dry-skin) — Superior fit — [$38.00 at Amazon](https://www.amazon.com/dp/B0DWXXJ9Q1?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [$21.70 at Amazon](https://www.amazon.com/dp/B084Q16G8D?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/dry-skin) — Average fit — [$115.00 at Amazon](https://www.amazon.com/dp/B01BMLQ086?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09XWPL5VN?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Cetaphil-focused routine

- Cleanser: [Gentle Skin Cleanser](https://lovi.care/skincare/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [$13.44 at Amazon](https://www.amazon.com/dp/B099N3NM61?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Healthy Radiance Brightness Refresh Toner](https://lovi.care/skincare/p/cetaphil/healthy-radiance-brightness-refresh-toner/for/dry-skin) — High fit — [$39.90 at Amazon](https://www.amazon.com/dp/B09C2CYDHD?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Rich Hydrating Night Cream](https://lovi.care/skincare/p/cetaphil/rich-hydrating-night-cream/for/dry-skin) — Superior fit — [$13.88 at Amazon](https://www.amazon.com/dp/B01MG4PVTR?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Sheer Mineral Sunscreen SPF 50](https://lovi.care/skincare/p/cetaphil/sheer-mineral-sunscreen-spf-50/for/dry-skin) — Superior fit — [$12.59 at Amazon](https://www.amazon.com/dp/B08HJKQP7X?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [$21.70 at Amazon](https://www.amazon.com/dp/B084Q16G8D?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Gentle Exfoliating SA Lotion](https://lovi.care/skincare/p/cetaphil/gentle-exfoliating-sa-lotion/for/dry-skin) — Caution fit — [$10.97 at Amazon](https://www.amazon.com/dp/B0CZDP1Q9H?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [$22.00 at Amazon](https://www.amazon.com/dp/B09XWPL5VN?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · $255.68 · 94% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B01N7T7JKJ&Quantity.1=1&ASIN.2=B08Q6WZ6J1&Quantity.2=1&ASIN.3=B0BTPGPK7H&Quantity.3=1&ASIN.4=B0DWXXJ9Q1&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B01BMLQ086&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine-20) [Buy Cetaphil routine · $134.48 · 83% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B099N3NM61&Quantity.1=1&ASIN.2=B09C2CYDHD&Quantity.2=1&ASIN.3=B01MG4PVTR&Quantity.3=1&ASIN.4=B08HJKQP7X&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0CZDP1Q9H&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 99% fit](https://lovi.care/skincare/skin/dry-skin)

### Cetaphil vs ISDIN routines for oily skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [$15.97 at Amazon](https://www.amazon.com/dp/B01N1LL62W?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [$15.60 at Amazon](https://www.amazon.com/dp/B08125WDCF?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — [$18.99 at Amazon](https://www.amazon.com/dp/B01CLTKI4A?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/p/isdin/eryfotona-actinica/for/oily-skin) — High fit — [$46.00 at Amazon](https://www.amazon.com/dp/B0CV8716J5?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0DNJKPSB8?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [$28.42 at Amazon](https://www.amazon.com/dp/B00KH6QX08?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/oily-skin) — High fit — [$115.00 at Amazon](https://www.amazon.com/dp/B01BMLQ086?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — [$79.00 at Amazon](https://www.amazon.com/dp/B0DQ5XJ5FK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Cetaphil-focused routine

- Cleanser: [Daily Facial Cleanser](https://lovi.care/skincare/p/cetaphil/daily-facial-cleanser/for/oily-skin) — Superior fit — [$11.88 at Amazon](https://www.amazon.com/dp/B09Y4HHY1P?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Healthy Radiance Brightness Refresh Toner](https://lovi.care/skincare/p/cetaphil/healthy-radiance-brightness-refresh-toner/for/oily-skin) — Average fit — [$39.90 at Amazon](https://www.amazon.com/dp/B09C2CYDHD?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Ceramide Serum](https://lovi.care/skincare/p/cetaphil/ceramide-serum/for/oily-skin) — High fit — [$13.99 at Amazon](https://www.amazon.com/dp/B0CZD72G5W?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Oil Control](https://lovi.care/skincare/p/cetaphil/oil-control/for/oily-skin) — Average fit — [$28.48 at Amazon](https://www.amazon.com/dp/B07GDM872R?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0DNJKPSB8?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [$28.42 at Amazon](https://www.amazon.com/dp/B00KH6QX08?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Gentle Exfoliating SA Lotion](https://lovi.care/skincare/p/cetaphil/gentle-exfoliating-sa-lotion/for/oily-skin) — Average fit — [$10.97 at Amazon](https://www.amazon.com/dp/B0CZDP1Q9H?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — [$79.00 at Amazon](https://www.amazon.com/dp/B0DQ5XJ5FK?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · $437.98 · 93% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B01N1LL62W&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B0CV8716J5&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B00KH6QX08&Quantity.6=1&ASIN.7=B01BMLQ086&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B0DQ5XJ5FK&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [Buy Cetaphil routine · $331.64 · 85% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B09Y4HHY1P&Quantity.1=1&ASIN.2=B09C2CYDHD&Quantity.2=1&ASIN.3=B0CZD72G5W&Quantity.3=1&ASIN.4=B07GDM872R&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B00KH6QX08&Quantity.6=1&ASIN.7=B0CZDP1Q9H&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B0DQ5XJ5FK&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 98% fit](https://lovi.care/skincare/skin/oily-skin)

### Cetaphil vs ISDIN routines for combination skin

#### ISDIN-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [$28.08 at Amazon](https://www.amazon.com/dp/B00AU9EBTC?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [$25.60 at Amazon](https://www.amazon.com/dp/B008EPPIQ4?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — [$18.99 at Amazon](https://www.amazon.com/dp/B01CLTKI4A?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/p/isdin/eryfotona-actinica/for/combination-skin) — High fit — [$46.00 at Amazon](https://www.amazon.com/dp/B0CV8716J5?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0DNJKPSB8?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [$18.90 at Amazon](https://www.amazon.com/dp/B09V7Z4TJG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/combination-skin) — High fit — [$115.00 at Amazon](https://www.amazon.com/dp/B01BMLQ086?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [$58.00 at Amazon](https://www.amazon.com/dp/B015RRNQCY?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

#### Cetaphil-focused routine

- Cleanser: [Daily Facial Cleanser](https://lovi.care/skincare/p/cetaphil/daily-facial-cleanser/for/combination-skin) — High fit — [$11.88 at Amazon](https://www.amazon.com/dp/B09Y4HHY1P?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Healthy Radiance Brightness Refresh Toner](https://lovi.care/skincare/p/cetaphil/healthy-radiance-brightness-refresh-toner/for/combination-skin) — High fit — [$39.90 at Amazon](https://www.amazon.com/dp/B09C2CYDHD?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Ceramide Serum](https://lovi.care/skincare/p/cetaphil/ceramide-serum/for/combination-skin) — High fit — [$13.99 at Amazon](https://www.amazon.com/dp/B0CZD72G5W?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Sheer Mineral Sunscreen SPF 50](https://lovi.care/skincare/p/cetaphil/sheer-mineral-sunscreen-spf-50/for/combination-skin) — Superior fit — [$12.59 at Amazon](https://www.amazon.com/dp/B08HJKQP7X?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0DNJKPSB8?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [$18.90 at Amazon](https://www.amazon.com/dp/B09V7Z4TJG?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Gentle Exfoliating SA Lotion](https://lovi.care/skincare/p/cetaphil/gentle-exfoliating-sa-lotion/for/combination-skin) — High fit — [$10.97 at Amazon](https://www.amazon.com/dp/B0CZDP1Q9H?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B071ZBJPH7?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [$58.00 at Amazon](https://www.amazon.com/dp/B015RRNQCY?tag=lovi-care-web-routine-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · $429.57 · 93% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B0CV8716J5&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B09V7Z4TJG&Quantity.6=1&ASIN.7=B01BMLQ086&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B015RRNQCY&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [Buy Cetaphil routine · $285.23 · 89% fit](https://www.amazon.com/gp/aws/cart/add.html?ASIN.1=B09Y4HHY1P&Quantity.1=1&ASIN.2=B09C2CYDHD&Quantity.2=1&ASIN.3=B0CZD72G5W&Quantity.3=1&ASIN.4=B08HJKQP7X&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B09V7Z4TJG&Quantity.6=1&ASIN.7=B0CZDP1Q9H&Quantity.7=1&ASIN.8=B071ZBJPH7&Quantity.8=1&ASIN.9=B015RRNQCY&Quantity.9=1&AssociateTag=lovi-care-web-routine-20) [See multi-brand routine · 97% fit](https://lovi.care/skincare/skin/combination-skin)

## Questions and answers

### Cetaphil or ISDIN: which is better?

Both brands are great choices depending on your skin goals, as Lovi rates their routines as High for Cetaphil and Superior for ISDIN across all skin types. Cetaphil is often preferred for gentle, non-stripping daily cleansing, while ISDIN is mostly known for its ultralight and makeup-friendly sunscreens.

### What is the difference between Cetaphil and ISDIN?

Cetaphil is an American brand that is exceptionally gentle on sensitive skin and focuses on versatile daily cleansing, whereas ISDIN is a Spanish brand known for ultralight, makeup-friendly sunscreens and lightweight moisturizers. Reviewers note that Cetaphil offers gentle cleansers and skin smoothing benefits, while ISDIN is praised for its ultralight sunscreens and brightening effects, though ISDIN tends to have a higher price point.

### Cetaphil or ISDIN for dry skin?

Both brands offer solid options for dry skin, with ISDIN achieving a Superior routine fit and Cetaphil reaching a High fit. ISDIN provides ultralight moisturizers and sunscreens, while Cetaphil is often noted for gentle, non-stripping cleansers and hydrating care.

### Cetaphil or ISDIN: which moisturizer is better?

Both brands offer moisturizers that help hydrate the skin, with Cetaphil providing options like its Rich Hydrating Night Cream and ISDIN featuring formulas such as Hyaluronic Moisture. Lovi rates Cetaphil's dry skin routine as High and ISDIN's routine as Superior, while reviewers note that ISDIN is known for lightweight moisturizers and Cetaphil is recognized for gentle, non-stripping hydration.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Which is more affordable, Cetaphil or ISDIN?

Cetaphil does better with pricing, while reviewers often complain about the high price point of ISDIN.

### Between Cetaphil and ISDIN, which brand has better options for brightening and complexion benefits?

ISDIN does better for brightening and complexion benefits, and the products on this page help improve skin tone. [Niacinamide](https://lovi.care/skincare/ingredients/niacinamide) also helps reduce pigmentation and suppress melanosome transfer.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### How do the fragrance options compare between Cetaphil and ISDIN products?

Cetaphil products on this page are generally fragrance-free, with 26 out of 27 listing no fragrance. In contrast, ISDIN products on this page more often include fragrance, as only 3 of their 8 products are fragrance-free.

### Which brand performs better for skin smoothing and texture improvements?

Cetaphil performs better for skin smoothing and texture improvements. Reviewers on this page frequently praise the products for helping refine skin texture.

### Cetaphil or ISDIN for oily skin?

For oily skin, both Cetaphil and ISDIN are well-suited options, as Lovi rates their routines as High and Superior, respectively. Reviewers frequently mention that Cetaphil offers gentle, non-stripping cleansers, while ISDIN is known for its ultralight sunscreens.

### Cetaphil or ISDIN: which sunscreen is better?

Both brands offer high-performing sunscreens on this page, with ISDIN featuring ultralight, makeup-friendly formulas and Cetaphil providing gentle options suitable for sensitive skin. Lovi rates the routine fit for both brands as Superior across all skin types.

### Cetaphil or ISDIN for sensitive skin?

Both brands are a good choice for sensitive skin, with Lovi giving Cetaphil a High fit and ISDIN a Superior fit. Cetaphil is known for being especially gentle with its largely fragrance-free range, while ISDIN offers ultralight sunscreens and lightweight moisturizers that reviewers like.

### Cetaphil or ISDIN for acne-prone skin?

Both brands are great choices for acne-prone skin, as Lovi rates the routine fit for this skin type as High for Cetaphil and Superior for ISDIN. Reviewers report that Cetaphil offers gentle, non-stripping cleansers while ISDIN provides ultralight, skin-friendly sunscreens.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide, Gentlebright complex · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Sodium ascorbyl phosphate ascorbic acid, Ascorbyl palmitate ascorbic acid · Experimental Dermatology, 2003
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Effects of menthol and cold on histamine-induced itch and skin reactions in man](https://pubmed.ncbi.nlm.nih.gov/7624016/) Peppermint leaf extract · Neuroscience Letters, 1995
- [Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/18489348/) Phytosphingosine · International Journal of Cosmetic Science, 2007
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Sodium ascorbyl phosphate ascorbic acid · Journal of Periodontology, 2009
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice powder · Clinical Pharmacology, 2018
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin](https://pubmed.ncbi.nlm.nih.gov/27349297/) Xylitol, Xylitylglucoside · Acta Dermato-venereologica, 2017
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin](https://pubmed.ncbi.nlm.nih.gov/25607907/) Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2015
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin](https://pubmed.ncbi.nlm.nih.gov/32657437/) Gentlebright complex · International Journal of Cosmetic Science, 2020
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum extract · Genes, 2020
- [Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study](https://pubmed.ncbi.nlm.nih.gov/34877760/) Sodium ascorbyl phosphate ascorbic acid · Dermatologic Therapy, 2022
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/38397772/) Ascorbyl palmitate ascorbic acid · Antioxidants, 2024
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [Structural characterization and in vivo evaluation of retinyl palmitate in non-ionic lamellar liquid crystalline system](https://pubmed.ncbi.nlm.nih.gov/21411295/) Retinyl palmitate · Colloids and Surfaces. B, Biointerfaces, 2011
- [A Dunaliella salina Extract Counteracts Skin Aging under Intense Solar Irradiation Thanks to Its Antiglycation and Anti-Inflammatory Properties](https://pubmed.ncbi.nlm.nih.gov/35200634/) Dunaliella salina extract · Marine Drugs, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol vitamin b5, Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Pha polyhydroxy acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract](https://pubmed.ncbi.nlm.nih.gov/32812663/) Rice extract lees extract · International Journal of Cosmetic Science, 2020
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Pha polyhydroxy acid · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity](https://pubmed.ncbi.nlm.nih.gov/27272074/) Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2016
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [In Vitro and Clinical Safety Assessment of the Multiple W/O/W Emulsion Based on the Active Ingredients from Rosmarinus officinalis L., Avena sativa L. and Linum usitatissimum L](https://pubmed.ncbi.nlm.nih.gov/34065623/) Avena sativa kernel extract oat kernel extract · Pharmaceutics, 2021
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome](https://pubmed.ncbi.nlm.nih.gov/37990616/) Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) Ascorbyl palmitate ascorbic acid · Frontiers in Pharmacology, 2025
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Modulation of lipid fluidity likely contributes to the fructose/xylitol-induced acceleration of epidermal permeability barrier recovery](https://pubmed.ncbi.nlm.nih.gov/30847563/) Xylitylglucoside · Archives of Dermatological Research, 2019
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites](https://pubmed.ncbi.nlm.nih.gov/23438139/) Retinyl palmitate · Journal of Cosmetic Dermatology, 2013
- [Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model](https://pubmed.ncbi.nlm.nih.gov/11867969/) Avena sativa kernel extract oat kernel extract · Skin Pharmacology and Applied Skin Physiology, 2002
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Xylitylglucoside · Molecules, 2021
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration](https://pubmed.ncbi.nlm.nih.gov/41129958/) Sodium pca · Biomaterials Advances, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
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- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
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- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026

## The brands

- American skincare: [Cetaphil](https://lovi.care/skincare/brands/cetaphil)
- Spanish skincare: [ISDIN](https://lovi.care/skincare/brands/isdin)

## More comparisons

- [SKIN1004 vs Cetaphil](https://lovi.care/skincare/compare/skin1004-vs-cetaphil)
- [SKIN1004 vs ISDIN](https://lovi.care/skincare/compare/skin1004-vs-isdin)
- [Anua vs Cetaphil](https://lovi.care/skincare/compare/anua-vs-cetaphil)
- [Anua vs ISDIN](https://lovi.care/skincare/compare/anua-vs-isdin)
- [Medicube vs Cetaphil](https://lovi.care/skincare/compare/medicube-vs-cetaphil)
- [Medicube vs ISDIN](https://lovi.care/skincare/compare/medicube-vs-isdin)
- [The Ordinary vs Cetaphil](https://lovi.care/skincare/compare/the-ordinary-vs-cetaphil)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/compare/the-ordinary-vs-isdin)
- [Beauty of Joseon vs Cetaphil](https://lovi.care/skincare/compare/beauty-of-joseon-vs-cetaphil)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/compare/beauty-of-joseon-vs-isdin)
- [COSRX vs Cetaphil](https://lovi.care/skincare/compare/cosrx-vs-cetaphil)
- [COSRX vs ISDIN](https://lovi.care/skincare/compare/cosrx-vs-isdin)
- [CeraVe vs Cetaphil](https://lovi.care/skincare/compare/cerave-vs-cetaphil)
- [CeraVe vs ISDIN](https://lovi.care/skincare/compare/cerave-vs-isdin)
- [La Roche-Posay vs Cetaphil](https://lovi.care/skincare/compare/la-roche-posay-vs-cetaphil)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/compare/la-roche-posay-vs-isdin)
- [Dr. Althea vs Cetaphil](https://lovi.care/skincare/compare/dr-althea-vs-cetaphil)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/compare/dr-althea-vs-isdin)
- [Some By Mi vs Cetaphil](https://lovi.care/skincare/compare/some-by-mi-vs-cetaphil)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/compare/some-by-mi-vs-isdin)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/cetaphil-vs-isdin (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/cetaphil-vs-isdin
- Ireland: https://lovi.care/skincare/ie/compare/cetaphil-vs-isdin
- Germany: https://lovi.care/skincare/de/compare/cetaphil-vs-isdin
- France: https://lovi.care/skincare/fr/compare/cetaphil-vs-isdin
- Italy: https://lovi.care/skincare/it/compare/cetaphil-vs-isdin
- Netherlands: https://lovi.care/skincare/nl/compare/cetaphil-vs-isdin
- Spain: https://lovi.care/skincare/es/compare/cetaphil-vs-isdin
- Canada: https://lovi.care/skincare/ca/compare/cetaphil-vs-isdin
- Australia: https://lovi.care/skincare/au/compare/cetaphil-vs-isdin
- Singapore: https://lovi.care/skincare/sg/compare/cetaphil-vs-isdin
- Saudi Arabia: https://lovi.care/skincare/sa/compare/cetaphil-vs-isdin
- United Arab Emirates: https://lovi.care/skincare/ae/compare/cetaphil-vs-isdin