# A+ vs ISDIN Isdinceutics

Page: https://lovi.care/skincare/compare/a-vs-isdin-isdinceutics

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

A+ and ISDIN Isdinceutics are two established international skincare brands offering gentle, thoughtfully calibrated formulas for various skin types. The Indian brand, founded in 1990, is widely beloved for its mild moisturizers that suit sensitive skin best and reliably support daily moisture balance, with the 345 Relief Cream standing out for acne-prone skin. Meanwhile, the Spanish brand, founded in 1975, is revered for its advanced formulas and targeted eye products that suit mature, dry, and sensitive skin, featuring the K-Ox Eyes cream to address dark circles and puffiness. While both brands emphasize gentle care, they differ in their heritage and specific product focus, with the former centering on daily moisture and the latter offering specialized solutions for a visibly rested complexion.

A+ is an Indian skincare brand founded in 1990.

[pitchbook.com](https://pitchbook.com/profiles/company/554388-85)

ISDIN Isdinceutics is a Spanish skincare brand founded in 1975 and owned by Puig since 2027.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/)

This page compares some of the most popular A+ and ISDIN Isdinceutics products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgecc24be0b0).

### Popular A+ vs ISDIN Isdinceutics products

#### ISDIN Isdinceutics

- [K-Ox Eyes](https://lovi.care/skincare/p/isdin-isdinceutics/k-ox-eyes/for/dry-skin) — High fit

#### A+

- [345 Relief Cream](https://lovi.care/skincare/p/a/345-relief-cream/for/sensitive-skin) — Average fit

## Questions and answers

### A+ or ISDIN Isdinceutics: which is better?

ISDIN Isdinceutics is the better fit for dry, sensitive, and mature skin, where Lovi rates its K-Ox Eyes product as High. However, A+ is the better choice if you want to avoid added fragrance, as every product on its page lists no fragrance.

### What is the difference between A+ and ISDIN Isdinceutics?

ISDIN Isdinceutics fits dry, sensitive, and mature skin at a High level with its eye product, while A+ fits most skin types on this page at an Average level with its moisturizer. Additionally, every product on the A+ page is fragrance-free, whereas the ISDIN Isdinceutics product on this page contains fragrance.

### Which is more affordable, A+ or ISDIN Isdinceutics?

Neither A+ nor ISDIN Isdinceutics is more affordable because the public page comparing them does not include price information for either brand.

### Which causes fewer breakouts, A+ or ISDIN Isdinceutics?

For acne-prone skin, Lovi rates A+ 345 Relief Cream as Average and ISDIN Isdinceutics K-Ox Eyes as Average.

### Which brand is older, A+ or ISDIN Isdinceutics?

A+ is older because it was founded in 1990, while ISDIN Isdinceutics was founded earlier in 1975.

### Do products from A+ or ISDIN Isdinceutics contain fragrance?

Every product on this page from A+ lists no fragrance in its ingredients, whereas ISDIN Isdinceutics includes fragrance in K-Ox Eyes, the only product from that brand on this page.

### Where were A+ and ISDIN Isdinceutics founded?

A+ was founded in India, and ISDIN Isdinceutics was founded in Spain.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage](https://pubmed.ncbi.nlm.nih.gov/21699266/) Chrysin · Journal of Agricultural and Food Chemistry, 2011
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation](https://pubmed.ncbi.nlm.nih.gov/19566395/) Ascorbyl palmitate · Journal of Microencapsulation, 2010
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- Indian skincare: [A+](https://lovi.care/skincare/brands/a)
- Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/brands/isdin-isdinceutics)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/a-vs-isdin-isdinceutics (this page)
- United Kingdom: https://lovi.care/skincare/uk/compare/a-vs-isdin-isdinceutics
- Ireland: https://lovi.care/skincare/ie/compare/a-vs-isdin-isdinceutics
- Germany: https://lovi.care/skincare/de/compare/a-vs-isdin-isdinceutics
- France: https://lovi.care/skincare/fr/compare/a-vs-isdin-isdinceutics
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- Netherlands: https://lovi.care/skincare/nl/compare/a-vs-isdin-isdinceutics
- Spain: https://lovi.care/skincare/es/compare/a-vs-isdin-isdinceutics
- Canada: https://lovi.care/skincare/ca/compare/a-vs-isdin-isdinceutics
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