# TIRTIR SOS Serum for mature skin

**Lovi Fit: Superior fit for mature skin.**
Normal Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [TIRTIR](https://lovi.care/skincare/ca/brands/tirtir)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for mature skin.

## Why this fit

- Excellent suitability for your normal skin is provided by the superb combination of humectant ingredients like Glycerin and Sodium Hyaluronate, alongside soothing agents such as Centella Asiatica Leaf Water and Chamomilla Recutita Flower Extract, which provide optimal hydration and calming benefits without overwhelming your skin.
- The targeted peptides, including Acetyl Hexapeptide-8 and Copper Tripeptide-1, work synergistically to promote collagen synthesis and enhance skin elasticity, effectively addressing your concerns with wrinkles and fine lines.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/mature-skin): Superior (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Leaf Water, Sodium Hyaluronate, Glycerin, Polyglutamic Acid, Allantoin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Curcumin-loaded polyglutamic acid and gum arabic electrospun nanofibers accelerated wound healing, increased TGF-beta1 and VEGF expression, reduced inflammatory factors, and enhanced re-epithelialization and tissue regeneration in a mouse model with acute full-thickness skin defects. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38554903/))
- Polyglutamic acid and polylysine composite hydrogels promote wound repair and hemostasis through high water absorption, bioadhesion, calcium ion-mediated coagulation factor activation, and inherent antibacterial properties in a deep skin defect model. ([Macromolecular Bioscience, 2021](https://pubmed.ncbi.nlm.nih.gov/33656254/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

This serum is widely praised as a "skin savior" for dehydrated, dull, and sensitive complexions, with users frequently reporting a "glass skin" glow and improved texture. While it excels at soothing redness and providing lightweight hydration for most, a small minority of users with very dry or reactive skin found it insufficiently moisturizing or experienced breakouts.

- Liked: Intense Hydration (mostly mentioned)
- Liked: Lightweight Texture (often mentioned)
- Liked: Soothing & Calming (often mentioned)
- Liked: Radiant Finish (sometimes noted)
- Liked: Makeup Compatibility (rarely noted)
- Disliked: Insufficient Moisture (rarely noted)
- Disliked: Lack of Results (rarely noted)
- Disliked: Price vs. Value (rarely noted)
- Disliked: Sensory Irritation (rarely noted)
- Disliked: Skin Reactions (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes TIRTIR SOS Serum one of the best fits for mature skin?

TIRTIR SOS Serum is one of the best fits for mature skin because it combines deeply hydrating ingredients like glycerin and sodium hyaluronate with calming botanical extracts to keep skin soft and comfortable. It also contains targeted peptides that help promote collagen production and improve elasticity, which effectively reduces the look of wrinkles and fine lines.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because it contains targeted peptides like Acetyl Hexapeptide-8 and Copper Tripeptide-1, which help boost collagen and smooth out fine lines. It also features a blend of Glycerin, Sodium Hyaluronate, and Centella Asiatica Leaf Water to provide deep hydration and calm the skin.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### What does Centella Asiatica Leaf Water do for mature skin?

Centella Asiatica Leaf Water helps calm mature skin and keeps it feeling soft and smooth by supporting moisture and protecting against daily irritation. Regular use may also improve skin firmness and elasticity while reducing the look of fine lines.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516082/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does it go in a skincare routine for mature skin?

This product goes in the evening routine as a treatment step after cleansing and before moisturizing, though some serums may also be used in the morning or twice a day. The formula relies on a blend of hydrating ingredients like glycerin and sodium hyaluronate alongside peptides to help improve fine lines and keep mature skin soft and smooth.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, applying the serum before your retinol or using it to help keep mature skin calm and hydrated during retinol use. A barrier-enhancing moisturizer helps improve skin comfort and supports your treatment routine.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

This treatment is a great fit for mature skin and is generally used in your evening routine, though some similar products can also be used in the morning or twice a day. Regular application helps keep skin hydrated and smooth while improving the look of fine lines and wrinkles.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can it clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores, cause breakouts, or lead to purging on mature skin because it features a safe, gentle formula built with calming extracts and hydrating ingredients. It is well-suited to keep dry or normal mature skin feeling smooth and comfortable without heavy or greasy oils.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

You can use this serum around the eyes, though the skin there is thin and delicate. It is unlikely to cause irritation due to its soothing ingredients and excellent safety profile, making it gentle enough for sensitive areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — CA$30.98 at Amazon
- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/ca/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — CA$199.19 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

- Amazon.ca: CA$33.64 (https://www.amazon.ca/dp/B08B1J1592?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Shoppers Drug Mart: CA$42.00 (https://www.shoppersdrugmart.ca/tirtir-sos-serum/p/BB_8809679690039?variantCode=8809679690039)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Centella Asiatica Leaf Water, Glycerin, Butylene Glycol, Witch Hazel Extract, 1,2-Hexanediol, Arginine, Carbomer, Cetyl Ethylhexanoate, Caprylyl Glycol, Sophora Flavescens Root Extract, Ficus Carica Fruit Extract, Ammonium Acryloyldimethyltaurate Vp Copolymer, C12-14 Pareth-12, Polyglyceryl-10 Laurate, Polyglyceryl-10 Myristate, Camellia Sinensis Leaf Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Betaine, Centella Asiatica Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Allantoin, Panthenol, Willow Bark Extract, Cucumis Sativus Fruit Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Disodium Edta, Chamaecyparis Obtusa Water, Spirodela Polyrhiza Extract, Alteromonas Extract Ferment, Illicium Verum Fruit Extract Anise Fruit Extract, Squalane, Phellinus Linteus Extract, Portulaca Oleracea Extract, Sodium Pca, Beta-Glucan, Sodium Hyaluronate, Xylitol, Polyglutamic Acid, Natto Gum, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/tirtir/sos-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/tirtir/sos-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/tirtir/sos-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/tirtir/sos-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/tirtir/sos-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/tirtir/sos-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/tirtir/sos-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/tirtir/sos-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/tirtir/sos-serum/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/tirtir/sos-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/tirtir/sos-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/tirtir/sos-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/tirtir/sos-serum/for/mature-skin