# The Ordinary Multi-Peptide + HA Serum for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [The Ordinary](https://lovi.care/skincare/ca/brands/the-ordinary)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for dry sensitive skin.

## Why this fit

- Excellent suitability for your dry and sensitive skin as multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 work synergistically with hydrating ingredients such as Sodium Hyaluronate Crosspolymer to plump and firm your skin.
- The inclusion of Allantoin and Glycerin further supports your skin barrier and provides essential moisture, addressing your dry or flaky skin concerns.
- The product is safe for your skin, containing no harsh ingredients and featuring soothing components that minimize irritation risk.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Multi-Peptides, Sodium Hyaluronate, Lactococcus Lysate Ferment, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Based on a very large amount of data, users with dry, mature, or dehydrated skin frequently praise this serum for its ability to plump the skin and smooth texture, often noting a reduction in fine dehydration lines. While many appreciate it as an affordable "all-in-one" anti-aging solution, a minority of users report breakouts or a lack of visible results regarding deeper wrinkles.

- Liked: Deeply hydrates (mostly mentioned)
- Liked: Great value (often mentioned)
- Liked: Smooths texture (often mentioned)
- Liked: Plumps and firms (sometimes noted)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Conflicts with actives (sometimes noted)
- Disliked: Unclear results (sometimes noted)
- Disliked: Allergic reactions (rarely noted)
- Disliked: Causes breakouts (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes The Ordinary Multi-Peptide + HA Serum a great fit for dry sensitive skin?

This serum is a great fit because multiple peptides work together with Sodium Hyaluronate to plump and firm dry skin. Glycerin and Allantoin support your skin barrier to provide essential moisture and help calm irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Which ingredients make this serum a good fit for dry sensitive skin?

This serum is a great fit for your dry sensitive skin because multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 work together with Sodium Hyaluronate Crosspolymer to plump and firm your skin. Additionally, Glycerin and Allantoin help support your skin barrier and provide essential moisture to soothe dry or flaky areas safely.
Sources: [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/)

### What do Peptides do for dry sensitive skin?

Peptides help hydrate dry sensitive skin while smoothing out the look of fine lines and improving overall stretchiness. Because some peptides have low skin penetration, products containing them often need extra supporting moisturizers and soothing ingredients to properly comfort very dry or reactive areas.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40565185/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in your evening routine, applied after cleansing and toning and before moisturizing. Putting treatments in the evening provides simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to give your dry and sensitive skin a boost of hydration, followed by your retinol. The soothing ingredients in this formula help keep irritation low while you use active treatments.

### How often should I use this serum?

You can use this serum in the evening as part of your routine. It is a great fit for your dry sensitive skin because hydrating ingredients like Sodium Hyaluronate Crosspolymer and soothing components like Allantoin help plump and calm your skin while minimizing irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts for dry sensitive skin, as its safety profile shows a very low likelihood of causing breakouts and contains soothing components to minimize irritation. Reviewers rarely report breakouts from using it.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-sensitive-skin) — High fit — CA$40.00 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-sensitive-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/dry-sensitive-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — CA$20.19 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/ca/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — CA$38.00 at Amazon

## Where to buy

- Amazon.ca: CA$23.50 (https://www.amazon.ca/dp/B0BLHW7JZM?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Sephora: CA$23.50 (https://www.sephora.com/ca/en/product/the-ordinary-deciem-buffet-P427420?skuId=2627198)
Prices checked 10 Oct – 3 Nov 2026.

## Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium Pca, Pca, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Ppg-26-Buteth-26, Peg-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin