# The INKEY List Mandelic Acid Treatment for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [The INKEY List](https://lovi.care/skincare/ca/brands/the-inkey-list)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate exfoliation for your combination skin, as mandelic acid and retinol work to regulate desquamation and address oily shine. This combination helps to gently refine skin texture and manage excess oil production.
- The presence of tocopherol ensures a soothing effect, making the formula generally well-tolerated for your skin type.
- The safety profile is excellent, with no harsh ingredients and a formulation designed to minimize irritation for combination skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/oily-acne-prone-skin): High

## Key ingredients

Mandelic Acid, Glycerin, Retinol, Ethyl Ferulate, Helianthus Annuus Seed Oil

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Treatment with 45% mandelic acid peel showed nearly equal overall efficacy as 30% salicylic acid peel in patients with mild-to-moderate facial acne vulgaris, but with fewer adverse effects. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31553119/))
- Chemical peels using 35% glycolic acid, 20% salicylic-10% mandelic acid, and phytic acid reduce acne scores by 70.55%, 74.14%, and 69.7% respectively, and significantly decline the postacne hyperpigmentation index in Asian patients with mild to moderate acne. ([Journal of Cutaneous and Aesthetic Surgery, 2019](https://pubmed.ncbi.nlm.nih.gov/31619887/))
- Commonly used chemical peels showed no significant differences in effectiveness for acne vulgaris in most comparisons, though combined salicylic and mandelic acid peeling was superior to glycolic acid and glycolic acid was superior to placebo, based on twelve randomized controlled trials. ([BMJ Open, 2018](https://pubmed.ncbi.nlm.nih.gov/29705755/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))

## What reviewers say

Users find this treatment effective for fading post-acne marks and hyperpigmentation, with a high frequency of positive comments noting its gentleness on sensitive skin. Many reviewers also appreciate its ability to improve skin texture and its affordable price point. A significant number of users mention that visible results require patience and consistent daily use over several weeks, and some find the natural scent unpleasant or the product size small.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Gentle on skin (often mentioned)
- Disliked: Slow to show results (often mentioned)
- Liked: Affordable price (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Small product size (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Sticky texture (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Mandelic Acid Treatment work for combination skin?

This treatment works reasonably well for your combination skin by providing moderate exfoliation and helping to manage oily shine. It is generally well-tolerated, though treatments that use ingredients like niacinamide, propolis, or zinc PCA often fit combination skin better by balancing moisture and oil without excess risk of imbalance.

### Which ingredients make this treatment a good fit for combination skin?

Mandelic acid and retinol help refine your skin and manage oily shine, while glycerin and tocopherol keep your skin soft and calm. To work even better for combination skin, a treatment of this type needs soothing and balancing ingredients like niacinamide, zinc PCA, and propolis to deliver optimal hydration and keep oiliness under control.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### What does mandelic acid do for combination skin?

Mandelic acid helps clear acne and smooth out uneven skin tone while being gentle enough to cause fewer side effects than other acids. It is well tolerated by various skin types and may help keep your face clear and calm.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31553119/), [BMJ Open, 2018](https://pubmed.ncbi.nlm.nih.gov/29705755/)

### What does glycerin do for combination skin?

Glycerin helps keep combination skin hydrated by drawing moisture into the skin and supporting the skin barrier. It is unlikely to irritate, making it useful for both dry and oily areas without feeling heavy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/)

### Where does this treatment go in a skincare routine for combination skin?

This treatment goes in the evening routine, after cleansing and before moisturizing. A product of this type needs gentle exfoliating acids and soothing hydrators to refine texture and manage excess oil on combination skin.

### Can I use this treatment with niacinamide, and in what order?

You can use this treatment with niacinamide by applying niacinamide first and following with this treatment once it absorbs, or by using niacinamide in the morning and this treatment at night. This helps keep combination skin smooth and balanced while minimizing any irritation. To work best for combination skin, this type of product needs soothing ingredients like glycerin and tocopherol along with gentle exfoliants.

### How often should I use this treatment?

Start by using this treatment once a week in the evening, and if your skin feels comfortable and you see good results, you can carefully use it more often. Combination skin of this type needs a treatment with hydrating ingredients and gentle exfoliants to help manage oily shine and keep the texture smooth without irritation.

### Can this treatment clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to clog pores or cause breakouts for your combination skin, as it has a very safe formula designed to avoid irritation and manage excess oil. A treatment of this type needs gentle exfoliating acids and soothing ingredients to refine texture without causing congestion.

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for combination skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — CA$24.44 at Amazon
- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/combination-skin) — High fit — CA$27.99 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/combination-skin) — Average fit — CA$33.98 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — CA$29.98 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Mandelic Acid, Coco-Caprylate Caprate, Cetearyl Alcohol, Glycerin, Sodium Hydroxide, Caprylic Capric Triglyceride, Glyceryl Stearate, Candelilla Jojoba Rice Bran Polyglyceryl-3 Esters, Sodium Stearoyl Glutamate, Phenoxyethanol, Sodium Stearoyl Lactylate, Benzyl Alcohol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Carnauba Cera, Retinol, Polysorbate 20, Ethylhexylglycerin, Dehydroacetic Acid, Helianthus Annuus Seed Oil, Trisodium Ethylenediamine Disuccinate, 1,2-Hexanediol, Caprylyl Glycol, Disodium Cocoamphodiacetate, Tocopherol, Xanthan Gum, Ethyl Ferulate, Humulus Lupulus Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- France: https://lovi.care/skincare/fr/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin (this page)
- Australia: https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin