# The History of Whoo Bichup Self-Generating Anti-Aging Concentrate for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: The History of Whoo
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few serums fit it even better.

## Why this fit

- High suitability for your dry and sensitive skin is offered by glycerin and biosaccharide gum-1, which provide humectant action to hydrate and soothe. Oligopeptides and acetyl hexapeptide-8 further contribute to minimizing fine lines and wrinkles, addressing your anti-aging goals.
- The inclusion of panthenol and shea butter offers additional hydration and soothing benefits, supporting your dry or flaky skin concerns.
- The product is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Ceramide Np, Panax Ginseng Root Extract, Copper Tripeptide-1, Hydrolyzed Soy Protein

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects. ([Rejuvenation Research, 2015](https://pubmed.ncbi.nlm.nih.gov/25867599/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline. ([Journal of Toxicology and Environmental Health. Part A, 2020](https://pubmed.ncbi.nlm.nih.gov/32564709/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))

## What reviewers say

Many users report plumper, firmer skin with diminished fine lines. However, some find the texture sticky and the floral fragrance overpowering.

- Liked: Deep hydration (often mentioned)
- Liked: Radiant glow (often mentioned)
- Disliked: Strong fragrance (often mentioned)
- Liked: Plumping effect (sometimes noted)
- Liked: Soothing & healing (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Awkward packaging (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes The History of Whoo Self-Generating Anti-Aging Concentrate a great fit for dry sensitive skin?

This treatment is a great fit because glycerin and biosaccharide gum-1 help hydrate and soothe dry, sensitive skin, while panthenol and shea butter provide extra comfort and relief from flakiness. Peptides also help minimize fine lines and wrinkles to support your anti-aging goals without irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Glycerin, biosaccharide gum-1, panthenol, and shea butter make this serum a great fit for your dry and sensitive skin by providing deep hydration and soothing benefits. These ingredients help keep your skin soft and comfortable while minimizing flaky patches.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### What do Ceramides do for dry sensitive skin?

Ceramides help hydrate dry sensitive skin and strengthen its outer barrier to reduce water loss and calm irritation. Using a product with ceramides often improves skin comfort and makes the skin feel much softer.
Sources: [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/), [Skin Pharmacology and Physiology, 2016](https://pubmed.ncbi.nlm.nih.gov/27251427/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment goes in your evening routine after your toner and before your moisturizer. Putting treatments in the evening helps keep your routine simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment after your toner and before your moisturizer in your evening routine, or right before your night cream. Using soothing ingredients like glycerin and panthenol helps keep dry sensitive skin comfortable and minimizes potential irritation from your routine.

### How often should I use this serum?

This treatment is intended for evening use as part of your routine. It is a great fit for your dry sensitive skin, helping to hydrate and soothe while minimizing fine lines.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores, cause breakouts or purging for your dry sensitive skin. Its formulation focuses on providing deep hydration and soothing benefits while maintaining a safe profile without harsh ingredients that typically trigger irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl salicylate, citronellol, geraniol, limonene, and linalool).

## Alternatives for dry sensitive skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-sensitive-skin) — High fit — CA$40.00 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-sensitive-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/dry-sensitive-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — CA$20.19 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/ca/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — CA$38.00 at Amazon

## Where to buy

- Amazon.ca: CA$105.91 (https://www.amazon.ca/dp/B007FG6IQM?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Dipropylene Glycol, Peg Ppg Polybutylene Glycol-8 5 3 Glycerin, Glyceryl Polymethacrylate, Biosaccharide Gum-1, Dimethicone, 1,2-Hexanediol, Peg-150, Propylene Glycol, Phenyl Trimethicone, Panthenol, Methyl Trimethicone, Cordyceps Sinensis Extract, Nelumbo Nucifera Extract, Nuphar Japonicum Root Extract, Panax Ginseng Root Extract, Ophiopogon Japonicus Root Extract, Rehmannia Chinensis Root Extract, Poria Cocos Extract, Dioscorea Japonica Root Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Typha Angustifolia Spike Extract, Paeonia Albiflora Extract, Scutellaria Baicalensis Root Extract, Angelica Gigas Extract, Saposhnikovia Divaricata Root Extract, Atractylodes Japonica Root Extract, Cinnamomum Cassia Bark Extract, Zingiber Officinale Root Extract, Ziziphus Jujuba Fruit Extract, Angelica Acutiloba Root Extract, Cornus Officinalis Fruit Extract, Velvet Extract, Theobroma Cacao Extract, Thymus Vulgaris Extract, Hydroxyproline, Ceramide Np, Cholesterol, Arbutin, Oligopeptide-1, Oligopeptide-2, Oligopeptide-4, Hydrolyzed Soy Protein, Acetyl Hexapeptide-8, Copper Tripeptide-1, Arginine, Cystine, Histidine Hcl, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, Tyrosine, Valine, Biotin, Folic Acid, Inositol, Niacinamide, Calcium Pantothenate, Pyridoxine Hcl, Riboflavin, Thiamine Hcl, Cyanocobalamin, Glycosphingolipids, Beta-Glucan, Hydrogenated Lecithin, Peg-10 Rapeseed Sterol, Glyceryl Stearate, Glycereth-20, C14-22 Alcohols, Phytosqualane, Macadamia Ternifolia Seed Oil, Triethylhexanoin, Arachidyl Glucoside, Butyrospermum Parkii Butter Shea Butter, Stearic Acid, Peg-100 Stearate, Polymethylsilsesquioxane, Cyclopentasiloxane, Dimethiconol, Butylene Glycol, Peg-60 Hydrogenated Castor Oil, Carbomer, Algin, Sodium Polyacrylate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sunset Yellow Fcf, Tartrazine, Tromethamine, Trisodium Edta, Alpha-Isomethyl Ionone, Benzyl Salicylate, Citronellol, Geraniol, Hydroxycitronellal, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin