Tatcha The Silk Serum for skin with dark spots

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Diglucosyl gallic acid exhibits stronger tyrosinase inhibition than VC with an IC50 of 2.68 mg/mL, and its application as a cosmetic ingredient improves skin brightness while reducing ultraviolet spots, melanin, and erythema in human volunteers.

  International Journal of Cosmetic Science, 2022

• Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.

  Experimental Dermatology, 2009

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• Bacterial cellulose wound dressing containing silk sericin and PHMB improved wound quality and reduced pain compared to Bactigras in patients with split-thickness skin graft donor-site wounds.

  Archives of Dermatological Research, 2018

• A bacterial nanocellulose wound dressing incorporating polyhexamethylene biguanide and sericin showed no skin irritation in healthy volunteers and significantly promoted wound healing with lower wound size and higher collagen formation in full-thickness rat wounds compared to controls.

  Archives of Dermatological Research, 2016

• Topical application of sericin gels increased skin intrinsic moisturization, hydroxyproline content, and epidermal hydration while decreasing transepidermal water loss and skin impedance in healthy human volunteers.

  Journal of Cosmetic Dermatology, 2005

• Daily application of a cream containing niosomes loaded with purple glutinous rice extract in 20 human volunteers for 28 days resulted in a significant decrease in melanin index and skin roughness by -14.05% and -9.95%, and increases in skin hydration and elastic recovery by +48.73% and +35.98% compared to initial values.

  International Journal of Cosmetic Science, 2020

• The iontophoretic delivery of hyaluronic acid nanogel-loaded Saccharomyces/Rice Ferment Filtrate significantly reduced advanced glycation end products and mitigated skin stiffening in an ex vivo skin tissue glycation model.

  International Journal of Nanomedicine, 2025

• Red rice extract suppressed UVB-induced inflammation and skin aging in human skin fibroblasts by inhibiting the MAPK signaling pathway, leading to decreased NF-kappa B and AP-1 activation, reduced ECM degradation, and increased ECM synthesis compared to UVB-irradiated controls.

  Natural Product Communications, 2016

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

Ingredients

Water, Saccharomyces Rice Ferment Filtrate, Glycerin, Betaine, Pentylene Glycol, Caprylic Capric Triglyceride, Propanediol, Cranberry Fruit Extract, Crithmum Maritimum Extract, Camellia Sinensis Leaf Extract, Cladosiphon Okamuranus Extract, Squalane, Sericin, Morus Alba Leaf Extract, Hydrolyzed Silk, Carthamus Tinctorius Seed Oil, Tetrapeptide-4, Polyglyceryl-10 Stearate, Diglucosyl Gallic Acid, Helianthus Annuus Seed Oil Sunflower Seed Oil, Hydrolyzed Conchiolin Protein, Caprylyl Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Prunus Amygdalus Dulcis Oil, Bergamot Oil Fruit, Lemon Peel Oil, Citrus Latifolia Peel Oil, Lavandula Angustifolia Oil Lavender Oil, Ocimum Basilicum Oil, Eucalyptus Globulus Oil Leaf, Juniperus Virginiana Oil, Amyris Balsamifera Oil Bark, 1,2-Hexanediol, Butylene Glycol, Sodium Citrate, Citric Acid, Disodium Edta, Potassium Hydroxide, Synthetic Fluorphlogopite, Tin Oxide, Citral, Limonene, Linalool, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide Ci 77891

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.